Clinical trials: Wound; Knee
PCL
Rehabilitation of Patient With Acute Isolated PCL Rupture
The posterior cruciate ligament injuries (PCL) is rare and rehabilitation methods are varying. The purpose of the study is to explore if one rehabilitation option is preferable to one other for patients with acute PCL injury, by…
- Trial name
- NCT02974205
- Testing
- Jack brace, Rehabilitation, össur brace
- Where
- 2 sites in Norway
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Anterior Cruciate Ligament Tear
Dynamic Knee Laxity Measurement Coupled to MRI in Cases of Suspected Partial Anterior Cruciate Ligament Tear
Anterior cruciate ligament (ACL) tear is frequent, but the diagnosis of partial tears is difficult. Standard MRI may be used but is of limited diagnostic value.
- Trial name
- LaxIRM (NCT02787096)
- Testing
- LaxIRM
- Where
- France
- Volunteers
- 151 people
- Sponsor
- Hospices Civils de Lyon
Ligament; Laxity, Knee, Rupture of Anterior Cruciate Ligament
Anterior Cruciate Ligament-reconstruction: Quadriceps Tendon or Hamstrings Tendon? A Prospective Trial
The purpose of this study is to determine whether there is a difference in muscle strength after anterior cruciate ligament comparing 2 surgery technics. Using either autograft hamstrings tendon or a autograft quadriceps tendon.
- Trial name
- NCT02173483
- Testing
- Quadriceps graft
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Aarhus University Hospital
Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Rupture
Altering Bone Microarchitecture and Mechanics by Off-label Pharmaceutical Intervention Following an Acute Knee Injury
The purpose of this study is to assess if a zoledronic acid injection can alter the trajectory of joint degeneration following an acute anterior cruciate ligament (ACL) injury.
- Conditions
- Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Injuries, Osteo Arthritis Knee
- Trial name
- ZAPOA (NCT05204836)
- Testing
- Zoledronic Acid Injection
- Where
- Canada
- Volunteers
- 4 people
- Sponsor
- University of Calgary
Anterior Cruciate Ligament Injuries
Operant Conditioning After ACL Reconstruction
The purpose of this study is to examine if the changes in corticospinal function that accompany ACL reconstruction can be improved through a form of mental coaching and encouragement, known as operant conditioning.
- Trial name
- NCT05519345
- Testing
- Operant Conditioning, Control
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Michigan
Anterior Cruciate Ligament Rupture
Initial Graft Tension and ACL Surgery
The anterior cruciate ligament (ACL) is one of four strong ligaments connecting the bones of the knee joint. If overstretched, the ACL can tear. Reconstruction of a torn ACL is now a common surgical procedure.
- Trial name
- NCT00434837
- Testing
- Initial graft tension during ACL reconstruction surgery
- Where
- 2 sites in United States
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
ACL - Anterior Cruciate Ligament Rupture
SharkScrew ACL RCT
This prospective, randomized controlled trial will compare three tibial interference screw types used for graft fixation during primary anterior cruciate ligament (ACL) reconstruction: a polyetheretherketone (PEEK) screw, a…
- Trial name
- NCT07830953
- Testing
- ACL Reconstruction with a Biocomposite Screw, ACL Reconstruction using a PEEK Screw, ACL Reconstruction using an Allograft Screw
- Where
- Austria
- Volunteers
- 33 people
- Sponsor
- Austrian Workers Compensation Board Styria
Iliotibial Band Syndrome
Clamshell and Frog Pump Exercises on Pain, Range of Motion, and Functional Disability
The study will be randomized clinical trial. This study will be conducted at the University of Lahore Teaching Hospital, Lahore, Pakistan.
- Trial name
- NCT07118371
- Testing
- Clamshell exercise, Frog pump exercises
- Where
- Pakistan
- Volunteers
- 92 people
- Sponsor
- University of Lahore
Osteoarthritis, Knee, Anterior Cruciate Ligament Injuries
Development of Computational Models to Predict the Short-, Medium- and Long-term Cartilage Degeneration and Pain for Patients With Early-stage Osteoarthritis or Anterior Cruciate Ligament Injury
Knee osteoarthritis is a complex condition, and selecting effective non-drug treatments like orthoses or exercise is often difficult and imprecise.
- Trial name
- MathKOA (NCT07134244)
- Where
- 2 sites in Denmark
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Anterior Cruciate Ligament Rupture
Assessing the Efficacy of a Preoperative Navigation System in Anterior Cruciate Ligament Reconstruction
The ACL surgery robot features a preoperative navigation system that enhances the precision of bone tunnel placement. As the first dual-bundle reconstruction surgical robot developed in China, it integrates advanced technology to…
- Trial name
- NCT06858930
- Testing
- ACL footprint localization after preoperative navigation executed by robotic arm, ACL footprint localization after preoperative navigation executed by rmanual execution
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Amputation, Traumatic, Gait
The Effect of Microprocessor Controlled Prostheses on Walking Pattern and Energy Consumption
The aim of this study was to investigate MIC and non-MIC prostheses in terms of gait pattern and energy consumption in above-the-knee amputee patients.
- Trial name
- NCT05786690
- Testing
- Interventions
- Volunteers
- 34 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Anterior Cruciate Ligament Rupture
Anterior Cruciate Ligament Reconstruction With a Periosteal - Patellar Tendon - Bone Autograft - The Kocabey Press-Fit Technique
This study aims to evaluate the clinical and radiological outcomes of patients undergoing anatomical single-bundle anterior cruciate ligament reconstruction with periosteal-patellar tendon-bone autograft and press-fit tibial…
- Trial name
- NCT06190223
- Testing
- Anterior cruciate ligament (ACL) reconstruction with a periost-patellar-tendon-bone (PPTB) autograft and a tibial press-fit technique
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Ankara City Hospital Bilkent
Osteoarthritis, Knee Cutaneous Suture, Dermabond, Subcuticular Suture
Comparison of Postoperative Wound Between Dermabond Prineo(2-octyl Cyanoacrylate Adhesive and Polyester Mesh) and Subcuticular Suture in Simultaneous Total Knee Arthroplasty
This study aims to compare the clinical results of postoperative wound between Dermabond PRINEO™(2-octyl Cyanoacrylate adhesive and polyester mesh) and subcuticular suture in simultaneous total knee arthroplasty There is previous…
- Trial name
- NCT04506580
- Testing
- DERMABOND™ PRINEO™(2-octyl Cyanoacrylate Adhesive and Polyester Mesh) vs subcuticular nylon suture
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- The Catholic University of Korea
Patella Fracture
High-Strength Suture vs. Traditional Tension Band for Patellar Fractures
This prospective cohort study aims to evaluate the clinical efficacy of high-strength suture modified tension band fixation in treating patellar fractures and compare it with traditional screw-cable tension band fixation.
- Trial name
- NCT07248982
- Testing
- High-Strength Suture Modified Tension Band Fixation, Screw-Cable Tension Band Fixation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Fuzhou University Affiliated Provincial Hospital
Osteoarthritis, Knee, Post-traumatic Osteoarthritis
Preventing Injured Knees From osteoArthritis: Severity Outcomes
This study is being done to find out if metformin is effective at reducing pain by delaying the onset of post-traumatic osteoarthritis (PTOA) after anterior cruciate ligament (ACL) reconstruction.
- Conditions
- Osteoarthritis, Knee, Post-traumatic Osteoarthritis, ACL Tear
- Trial name
- PIKASO (NCT06096259)
- Testing
- Metformin
- Where
- 9 sites in United States
- Volunteers
- 512 people
- Sponsor
- Brigham and Women's Hospital
Knee Injuries
Establishing the Clinical Significance Values of the Lysholm Knee Score
The goal of this observational study is to learn about patients who will undergo anterior cruciate ligament reconstruction. The main questions it aims to answer are: What is the minimal clinically important difference value of…
- Trial name
- NCT06571227
- Testing
- Anterior cruciate ligament reconstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Kırklareli University
ATTR Amyloidosis, Cardiopathy
Orthopaedic Specimen Pathology and Early Diagnosis of ATTR Cardiopathy (ATTR-ORTHO)
The goal of this observational study is to learn about the frequency of ATTR amyloid, cardiac involvement and associated features, in 150 patients aged 50 or more years, and operated for an idiopathic carpal tunnel syndrome…
- Conditions
- ATTR Amyloidosis, Cardiopathy, Carpal Tunnel Syndrome, Lumbar Spine Stenosis
- Trial name
- ATTR-ORTHO (NCT06367842)
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Institut Mutualiste Montsouris
Anterior Cruciate Ligament Injury, Knee Injuries
Bone Tunnel Widening Following ACL Reconstruction
Hypothesis 1: There is less tunnel-widening with bone-patella tendon-bone graft compared with the hamstring graft when the same fixation method is used.
- Trial name
- NCT00198042
- Testing
- Surgical reconstruction of the ACL
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
ACL Reconstruction
Psychological and Physiological Parameters for Return-to-sport After ACL Reconstruction
Injuries to the anterior cruciate ligament are common and are usually treated with reconstruction and subsequent rehabilitation. Many people succeed in return to sport (RTS), but not to the original level.
- Trial name
- ACL-RTS (NCT07259083)
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Johannes Kepler University of Linz
Anterior Cruciate Ligament Rupture
Pain Relief Results After Anterior Cruciate Ligament (ACL) Reconstruction
Anterior cruciate ligament (ACL) reconstruction is surgery that is done to repair a damaged ligament in the knee. In this study we will look at whether the femoral nerve block, a commonly used method for pain relief after ACL…
- Trial name
- NCT00022854
- Testing
- Single-injection femoral nerve block, Femoral nerve block 60-hour continuous injection, Saline (control) injection into femoral nerve envelope
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of Pittsburgh
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