Clinical trials: Wound; Knee
Knee Osteoarthritis (Knee OA)
Knee OsteoArthritis Long-term Assessment
The goal of this clinical study is to learn if Hydrogel OA 2% injection is safe and whether it works to improve symptoms of diagnosed knee osteoarthritis in adults when compared to Hyaluronic Acid (Durolane), a treatment that is…
- Trial name
- KOALA (NCT06839222)
- Testing
- Hydrogel OA 2%, Hyaluronic Acid (Durolane)
- Where
- 5 sites in Belgium
- Sponsor
- Allegro NV/SA
Fracture of Patella
Clinical Outcome After Treatment of Patellar Fractures With Locking Plates
Depending on the fracture pattern of patellar fractures tension band wiring, interfragmentary screw fixation or combinations are common treatments.
- Trial name
- NCT02015975
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Diakoniekrankenhaus Friederikenstift
Behavior, Amputation
Self-Management for Amputee Rehabilitation Using Technology.
Lower Limb Amputations (LLAs) are a substantial burden on the Canadian health services with nearly 50,000 cases reported between 2006 and 2011.
- Conditions
- Behavior, Amputation, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury)
- Trial name
- SMART (NCT04953364)
- Testing
- SMART, Control
- Where
- Canada
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
ACL Injury, Pain
Effect of Biophysical Stimulation on Intraspongious Bone Edema in Anterior Cruciate Ligament Reconstruction
The following study has as main objective to evaluate whether the use of I-ONE® therapy can reduce post-operative pain thanks to the modulation of inflammation in patients with bone bruise on the knee after anterior cruciate…
- Conditions
- ACL Injury, Pain, Magnetic Field Exposure
- Trial name
- NCT04255407
- Testing
- I-ONE® therapy, Anti-inflammatory drug
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Istituto Ortopedico Rizzoli
Anterior Cruciate Ligament Injuries
Operant Conditioning After ACL Reconstruction
The purpose of this study is to examine if the changes in corticospinal function that accompany ACL reconstruction can be improved through a form of mental coaching and encouragement, known as operant conditioning.
- Trial name
- NCT05519345
- Testing
- Operant Conditioning, Control
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Michigan
Wound of Knee
Wound Closure After Total Knee Replacement
To compare the wound healing after total knee replacement wound closure with staples versus subcuticular prolene suture.
- Trial name
- NCT03788239
- Testing
- Staples versus sutures
- Where
- Pakistan
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Indus Hospital and Health Network
Patellofemoral Pain Syndrome, Medial Tibial Stress Syndrome
Do Simple Running Technique Changes Reduce Pain and Change Injury Causing Mechanics
This project aims to investigate whether an increase in step rate can be used to reduce pain and injury causing movement patterns in runners who are currently experiencing achilles tendonopathy, iliotibial band syndrome…
- Conditions
- Patellofemoral Pain Syndrome, Medial Tibial Stress Syndrome, Iliotibial Band Syndrome, Achilles Tendinopathy
- Trial name
- NCT03067545
- Testing
- Step rate increase
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Salford
Fracture of Tibia Proximal Plateau
Immediate Versus Late Weight Bearing After Tibial Plateau Fractures Internal Fixation
Postoperative rehabilitation for tibial plateau fracture generally involves prolonged non-weight bearing time while other protocols use partial weight-bearing and bracing before full weight-bearing is recommended at 9 to 12 weeks…
- Trial name
- NCT05502679
- Testing
- Weight bearing as tolerated, Pragmatic Exercise protocol
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Assiut University
Anterior Cruciate Ligament Rupture
Are Clinical Outcomes Unchanged by ALL Fixation at 0° or 30° of Knee Flexion in Combined ACL-ALL Reconstruction? Despite Numerous Technical Descriptions of Anterolateral Procedures, There is Limited Knowledge Regarding the Effect of Knee Flexion Angle During Graft Fixation.
This study evaluates whether the knee flexion angle used during fixation of the anterolateral ligament (ALL) affects clinical outcomes in patients undergoing combined anterior cruciate ligament (ACL) and ALL reconstruction.
- Trial name
- ACL ALL (NCT07451743)
- Testing
- anterolateral ligament reconstruction
- Volunteers
- 100 people
- Sponsor
- ASL Lecce
Meniscus Tears, Loose Bodies
Clinical Efficacy Study Comparing VisionScope Imaging (VSI) to Magnetic Resonance Imaging (MRI) in Injuries of the Knee
The purpose of the study is to accumulate efficacy data on VisionScope Imaging (VSI) for pre-operative diagnosis of certain knee injuries (meniscal and articular cartilage injuries).
- Conditions
- Meniscus Tears, Loose Bodies, Articular Osteoarthritis, Articular or Capsular Trauma
- Trial name
- VSI-001 (NCT01695720)
- Testing
- VisionScope Imaging (VSI) Exam
- Where
- 7 sites in United States
- Volunteers
- 105 people
- Sponsor
- VisionScope Technologies
ACL Tear
Readiness Outcomes Affecting Return to Sport 2.0: An Intervention Feasibility & Pilot Study
This study aims to determine the feasibility of implementing a mental skills training intervention for adolescent athletes who tear their ACL and undergo ACL reconstruction surgery alongside receiving standard-of-care clinical…
- Trial name
- ROAR 2:Pilot (NCT05338385)
- Testing
- Mental Skills Coaching
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Boston Children's Hospital
Knee Injuries, Anterior Cruciate Ligament Rupture
Stopping OsteoARthritis After an ACL Tear
By 2040, 25% of Canadians will have osteoarthritis, a disabling joint condition. Most people think osteoarthritis only affects older adults, but 50% of the 700,000 Canadian youth who hurt their knee playing sports annually will…
- Conditions
- Knee Injuries, Anterior Cruciate Ligament Rupture, Osteoarthritis, Knee
- Trial name
- SOAR (NCT06195423)
- Testing
- Stop OsteoARthritis (SOAR) program, Living Well after ACLR program
- Where
- 2 sites in Canada
- Volunteers
- 210 people
- Sponsor
- University of British Columbia
Pain, Postoperative, Anterior Cruciate Ligament Injuries
IPACK on Early Pain Scores After ACL Reconstruction
The goal of this clinical trial is to learn whether using an anesthetic technique called IPACK block will control pain after ACL reconstruction surgery.
- Conditions
- Pain, Postoperative, Anterior Cruciate Ligament Injuries, Analgesics, Opioid
- Trial name
- NCT05985629
- Testing
- IPACK
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Loyola University
Hamstring Tightness, Hamstring Injury Prevention
The Effectiveness of Muscle Energy Technique and Friction Massage in Hamstring Tightness Amongst Young Athletes of Pakistan
The ability of an individual to move smoothly depends on his flexibility, an attribute that enhances both safety and optimal physical activity.
- Trial name
- NCT03680300
- Testing
- Post Facilitation Stretch, Post Isometric Relaxation, Friction Massage
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Isra University
Iliotibial Band Syndrome
Exercise Program for ITB Syndrome
Patients with diagnosed iliotibial band (ITB) syndrome indicated for non-operative management will be randomized to individualized exercise program or standard physical therapy over the course of 3 months to determine any…
- Trial name
- NCT06269757
- Testing
- Individualized Exercise Program, Standard Physical Therapy
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Reconstruction
Comparison of Kinematic Movements Between ACL Deficiency With ACL Reconstruction and Healthy People
Comparison of kinematic movements between patients with anterior cruciate ligament rupture and post-operative patients and normal people using a mobile dynamic X-ray device.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Reconstruction, Healthy People
- Trial name
- NCT05619393
- Testing
- Mobilie Bi-planar X-ray Imaging system
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Wang Joon Ho
ACL Reconstruction
Psychological and Physiological Parameters for Return-to-sport After ACL Reconstruction
Injuries to the anterior cruciate ligament are common and are usually treated with reconstruction and subsequent rehabilitation. Many people succeed in return to sport (RTS), but not to the original level.
- Trial name
- ACL-RTS (NCT07259083)
- Where
- Austria
- Volunteers
- 30 people
- Sponsor
- Johannes Kepler University of Linz
Anterior Cruciate Ligament Injuries, Quadriceps Muscle Atrophy
The Effect of PEMF for Patients With Quadriceps Muscle Weakness After ACLR
In Hong Kong, over 3000 Anterior Cruciate Ligament Reconstructions (ACLR) are performed each year in order to restore knee function after an ACL injury. The ultimate goal of ACLR is to fulfil the return-to-play (RTP) criteria.
- Trial name
- NCT05184023
- Testing
- Pulse Electromagnetic Field
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Chinese University of Hong Kong
ACL Injury, ACL - Anterior Cruciate Ligament Rupture
Improving ACL Reconstruction Outcomes: CBPT
The overall objective of this study is to conduct a two-group randomized trial to examine the efficacy of cognitive-behavioral based physical therapy (CBPT) for improving knee function, return to sport, and quality of life…
- Conditions
- ACL Injury, ACL - Anterior Cruciate Ligament Rupture, ACL Sprain, ACL Tear
- Trial name
- NCT03243162
- Testing
- CBPT-ACLR, Education
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Vanderbilt University Medical Center
Knee Osteoarthritis
Hydrolyzed Collagen Formulation vs Placebo in Knee Osteoarthritis
The aim of the study is to compare the 6 months clinical outcome of the treatment with a single intra-articular collagen injection versus a single placebo (saline solution) infiltration in the infiltrative treatment of knee…
- Trial name
- NCT04998188
- Testing
- Collagen
- Where
- Italy
- Volunteers
- 204 people
- Sponsor
- Istituto Ortopedico Rizzoli
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