Clinical trials: Wound; Knee
Kinesiophobia, ACL Injury
Kinesiophobia After Anterior Cruciate Ligament Reconstruction.
Anterior cruciate ligament (ACL) rupture is a serious trauma with long-term consequences to the athlete. Psychological and physiological factors may negatively affect patient recovery and increase reinjury rate after anterior…
- Trial name
- NCT05762809
- Testing
- Tampa Scale of Kinesiophobia (TSK-17), Knee injury and Osteoarthritis Outcome Score (KOOS), Oxford Knee Score (OKS) scoring
- Where
- Estonia
- Volunteers
- 144 people
- Sponsor
- Tartu University Hospital
Knee Osteoarthritis, Postoperative Pain
Ultrasound-Guided PASC Block vs Femoral-Sciatic Nerve Block for Postoperative Analgesia After Total Knee Arthroplasty
This randomized, double-blind comparative study evaluates postoperative analgesic efficacy and motor effects of ultrasound-guided para-sartorial compartments (PASC) block versus ultrasound-guided combined femoral-sciatic nerve…
- Conditions
- Knee Osteoarthritis, Postoperative Pain, Total Knee Arthroplasty
- Trial name
- NCT07320833
- Testing
- Ultrasound-Guided Femoral Nerve Block plus Sciatic Nerve Block, Ultrasound-Guided Para-sartorial Compartments Block
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Ain Shams University
ACL Surgery, ACL Injuries
Developing and Validating the Risk-taking Intention and Sport Engagement After ACL Reconstruction (RISE-ACL) Scale
Psychological factors play a critical role in recovery following anterior cruciate ligament (ACL) reconstruction. While tools such as the ACL - Return to Sport after Injury (ACL-RSI) focus on psychological readiness, emphasizing…
- Conditions
- ACL Surgery, ACL Injuries, ACL Reconstruction
- Trial name
- RISE-ACL (NCT06748066)
- Testing
- RISE-ACL development, RISE-ACL scale validation
- Where
- France
- Volunteers
- 162 people
- Sponsor
- University Hospital, Caen
Proximal Tibia Fracture
The Efficacy and Cost Effectiveness of Preoperative and Postoperative Cryotherapy in Proximal Tibia Fractures
Consenting patients with proximal tibia fractures will be randomized to 10 degree or 21 degree cryotherapy sleeves. Time to discharge and complications will be monitored.
- Trial name
- ARCTIC CAT (NCT01104831)
- Testing
- Cryotherapy, Room temperature cuff
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Tear
Utilization of a 3D Printed Customized Knee Extender and At-Home Rehabilitation Program on Patient Outcomes Following ACL Surgery
The purpose of this study is to explore patient outcomes associated with, the use of a 3D printed knee extender device, in conjunction with an at-home rehabilitation program, for patients who are performing knee rehabilitation…
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Tear, Anterior Cruciate Ligament Rupture
- Trial name
- NCT06524349
- Testing
- 3D printed knee extender device
- Where
- 2 sites in United States
- Volunteers
- 45 people
- Sponsor
- Sanford Health
Chondral Defect, Articular Cartilage Defect
A Comparison of JointRep® and Microfracture in Repair of Cartilage Lesions on the Femoral Condyle or Trochlea,
The aim of the study is to compare whether JointRep® plus microfracture is more effective than microfracture alone when treating symptomatic focal articular cartilage lesions in the knee (femoral condyles or trochlea).
- Conditions
- Chondral Defect, Articular Cartilage Defect, Articular Cartilage Disorder of Knee
- Trial name
- JMAC (NCT04840147)
- Testing
- JointRep®, Microfracture
- Where
- 8 sites in Australia, Canada
- Volunteers
- 185 people
- Sponsor
- Oligo Medic Pty Ltd
Anterior Cruciate Ligament Injuries
Prolonged Preoperative Rehabilitation in ACL Rupture.
Rupture of the anterior cruciate ligament is a serious and common injury. In young athletes, surgical reconstruction of the anterior cruciate ligament by autograft with hamstrings or patellar ligament is widely used.
- Trial name
- ISO-LCA-PREOP (NCT04888052)
- Testing
- Acute ACL injury
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Lille
Anterior Cruciate Ligament Rupture, Donor Site Complication
BTB Graft Harvest and Donor Site Morbidity After ACL Reconstruction
The aim of this observational study is to examine the connection between bone-tendinous defects after BTB graft harvest and the development of anterior knee pain.
- Trial name
- NCT06030791
- Testing
- MRI
- Where
- Serbia
- Volunteers
- 60 people
- Sponsor
- Clinical Center of Vojvodina
Knee Ligament Injury
Predictive Factors of Good Results After Multiligamentar Knee Reconstruction (MLKR)
Multiligamentar knee injury has consequences on knee function (instability, arthritis, life disagreement). Surgical reconstructions have known recent evolutions.
- Trial name
- NCT06024850
- Testing
- Datas collected
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Anterior Cruciate Ligament Injuries
Efficacy of the NXSignal Device for the Treatment of Anterior Cruciate Ligament Injuries
Injury to the anterior cruciate ligament (ACL) is very common among sports professionals and the general population [. Unlike other joint injuries, it is reversible, but it can damage adjacent tissues, particularly the meniscus…
- Trial name
- NCT05207943
- Testing
- Non-invasive Neuromodulation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Las Palmas de Gran Canaria
Patellar Luxation, Patellar Instability
Clinical Outcome of the Dynamic Reconstruction of the Medial Patellofemoral Ligament (MPFL)
In a single surgical center, 213 consecutive patients with 221 knees were surgically treated for recurrent lateral patellar dislocation between 07/2010 and 12/2016.
- Trial name
- NCT04438109
- Where
- Germany
- Volunteers
- 152 people
- Sponsor
- Hannover Medical School
Meniscal Degeneration, Osteoarthritis of Knee
Evaluation of Clinical and Radiographic Outcomes of Meniscal Lesion Treatment Using Collagen Scaffolds (CMI)
Meniscal lesions represent the most frequently encountered joint pathology in the adult population and can cause pain symptoms, mechanical blockages, and recurrent effusions.
- Conditions
- Meniscal Degeneration, Osteoarthritis of Knee, Meniscus Injury
- Trial name
- SUPER CMI (NCT06597357)
- Testing
- Arthroscopy & saline irrigation alone
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Istituto Ortopedico Rizzoli
Knee Injuries, Knee Arthritis
Kinematic Parameters to Predict Knee Diseases.
There is no study to explore the prediction of knee diseases using kinematic parameters of knee during gait. The aim of this study is to explore the possibility of predicting knee diseases by gait parameters.
- Trial name
- NCT03130400
- Testing
- Observational gait analysis procedure
- Where
- China
- Volunteers
- 1,914 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Anterior Cruciate Ligament Injury
Motor Imagery to Facilitate Sensorimotor Relearning After ACL Injury
Anterior cruciate ligament injury is a common issue in sports involving cutting and jumping. Treatment may include surgical intervention followed by physical therapy, or no surgical intervention with the main treatment being…
- Trial name
- MOTIFS (NCT03473821)
- Testing
- MOTIFS
- Where
- Sweden
- Volunteers
- 106 people
- Sponsor
- Lund University
Arthritis, Osteoarthritis
The SOAR (Stop OsteoARthritis) Program Proof-of-Concept Study
Adolescents and young adults who hurt their knees playing sports or doing recreational activities can develop joint damage, muscle weakness, inactivity, and weight gain which might lead to an increased risk of osteoarthritis…
- Conditions
- Arthritis, Osteoarthritis, Arthritis Knee, Osteo Arthritis Knee
- Trial name
- SOARPOC (NCT04956393)
- Testing
- Immediate 8-Week SOAR Program, Delayed 8-Week SOAR Program
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
ACL Reconstruction, Tenodesis
Clinical and Biomechanical Outcomes of Anterior Cruciate Ligament (ACL) Reconstruction Associated With Lateral Extra-articular Tenodesis (LET)
The anterior cruciate ligament (ACL) is one of the main stabilizers of the knee joint, and its injury is among the most common soft tissue injuries of the knee.
- Conditions
- ACL Reconstruction, Tenodesis, ACL Injuries
- Trial name
- LETOTT (NCT07049484)
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- Stefano Zaffagnini
ACL - Anterior Cruciate Ligament Rupture
Comparison of Arthrogenic Muscle Inhibition (AMI) After ACL Reconstruction in Patients With Conventional Rehabilitation or Conventional Rehabilitation Combined With Digital Therapy
Traumatic injury to the knee joint, such as rupture of the anterior cruciate ligament (ACL), can compromise the voluntary activation capacity of the quadriceps despite the anatomical integrity of the nerve and muscle structures…
- Trial name
- AMITHENUM (NCT07030764)
- Testing
- DOCT'UP, Physiotherapy
- Where
- France
- Volunteers
- 448 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Clinical Practice Guidelines, Lower Limb Amputation Above Knee (Injury)
TeleEducation for Implementing a Clinical Practice Guideline For Amputees
The publication of a Clinical Practice Guideline (CPG) is often not enough for its correct use in the field of health care. There are barriers to the implementation of the CPG recommendations, including those related to the lack…
- Conditions
- Clinical Practice Guidelines, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury), Lower Limb Amputation Knee
- Trial name
- TEFICA (NCT05601349)
- Testing
- Telehealth-based strategy
- Where
- Colombia
- Volunteers
- 7 people
- Sponsor
- Grupo Rehabilitacion en Salud
Cerebral Palsy, Muscular Dystrophy
Evaluating Long-term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children With Movement Disorders
Background: People with cerebral palsy, spina bifida, muscular dystrophy, or spinal cord injury often have muscle weakness and problems controlling how their legs move. This can affect how they walk.
- Conditions
- Cerebral Palsy, Muscular Dystrophy, Spina Bifida, Incomplete Spinal Cord Injury
- Trial name
- NCT05726591
- Testing
- EA-KAFO
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Knee Osteoarthritis, Arthritis
Inflammatory Response Conventional Total Knee Replacement Versus Mako Total Knee Replacement
Total knee Arthroplasty (TKA) is a highly effective treatment for knee osteoarthritis. Mid- to long-term follow-up studies have shown good clinical outcomes following TKA; despite these results, there is a high incidence of…
- Conditions
- Knee Osteoarthritis, Arthritis, Surgery
- Trial name
- NCT04192006
- Testing
- Total Knee Arthroplasty
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University College, London
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