Clinical trials: Wound Closure
Skin Closure of Surgical Incisions by Tissue Glue vs Suture
Tissue Glue (Cyanoacrylate) Versus Conventional Suture in Kidney Donors
By means of a prospective, randomised trial the investigators want to examine skin closure in living donors - subjected to laparoscopic, hand-assisted nephrectomy - by tissue glue (Cyanoacrylate (Liquiband)) versus conventional…
- Trial name
- TG-CYANO (NCT01521871)
- Testing
- Skin wound closure by tissue glue, Skin wound closure by conventional suture + dressing
- Where
- Norway
- Volunteers
- 64 people
- Sponsor
- Oslo University Hospital
Wound Healing
Comparison of Two Methods of Securing Skin Grafts Using Negative Pressure Wound Therapy: Vacuum Assisted Closure (VAC) and Gauze Suction (GSUC)
The purpose of this study is to compare how well two methods (VAC and G-SUC) of securing skin grafts using negative pressure wound therapy work.
- Trial name
- NCT00952120
- Testing
- GSUC, VAC
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of Chicago
CSF Leak
The Paediatric EVICEL® Neuro Study
The purpose of this study is to evaluate the safety and efficacy of EVICEL® when used for suture-line sealing in dura-mater closure in elective or urgent paediatric cranial neurosurgery to provide intraoperative watertight…
- Trial name
- NCT02309645
- Testing
- EVICEL® Fibrin Sealant, Sutures Only
- Where
- 7 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- Ethicon, Inc.
Wound Closure Technique
A Comparison of Polyglactin 910 and Chromic Gut Suture in the Closure of Punch Biopsy Sites
Some Dermatologists prefer absorbable suture to non-absorbable suture in the closure of punch biopsy sites. The reason these are often preferred is because patients do not have to pay for another visit to get the suture material…
- Trial name
- NCT01722994
- Testing
- Polyglactin 910 sterile synthetic absorbable suture (Ethicon), Chromic Gut Sterile absorbable Suture (Ethicon)
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- University of Mississippi Medical Center
Surgical Wound
A Clinical Trial of Subcuticular Staples Versus Subcuticular Suture for Cesarean Section Skin Closure
Currently, the way doctors close the skin during cesarean section is different between surgeons and there is little evidence to support the use of one kind of closure over the other.
- Trial name
- NCT01753518
- Testing
- Subcuticular suture, Subcuticular staple
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Margaret L. Dow, M.D.
Surgical Incision
Secondary Versus Tertiary Wound Closure in High Risk Gynecologic Abdominal Surgical Incisions
The purpose of this research study is to determine if closing a surgical wound differently is better than the procedure that is currently used.
- Trial name
- NCT03861065
- Testing
- Tertiary Wound Closure, Historical Wound Closure
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Wake Forest University Health Sciences
Wound Closure
Symmetric on Total Knee Arthroplasty (TKA)
A post-marketing prospective, multicenter, randomized controlled study to evaluate the wound closure efficiency of STRATAFIX™ Symmetric PDS™ Plus Knotless Tissue Control Device (STRATAFIX Symmetric PDS Plus) compared to…
- Trial name
- SFX (NCT03305887)
- Testing
- "STRATAFIX™ Symmetric" Knotless Tissue, VICRYL® PLUS, "STRATAFIX Spiral" sutures
- Where
- 7 sites in China
- Volunteers
- 184 people
- Sponsor
- Johnson & Johnson Medical, China
Burns
Oleogel-S10 Versus Standard of Care in Healing of Grade 2a Burn Wounds
The main goal of this phase III clinical trial is to show safety and efficacy of Oleogel-S10 in the acceleration of wound healing of grade 2a burn wounds.
- Trial name
- NCT01657292
- Testing
- Oleogel-S10 ointment, Octenilin® wound gel
- Where
- 9 sites in Germany, Sweden and 2 more
- Volunteers
- 61 people
- Sponsor
- Birken AG
Cesarean Section, Complication
A Skin Glue Versus Subcuticular Suture for Cesarean Closure Study
The aim of this study is to compare cesarean incision outcomes between patients with incision closed with the Dermabond Prineo system compared to standard subcuticular suture.
- Conditions
- Cesarean Section, Complication, Wound
- Trial name
- NCT05903547
- Testing
- Dermabond Prineo, Suture
- Where
- United States
- Volunteers
- 151 people
- Sponsor
- Columbia University
Surgical Wound
The Closer Trial: A Safety and Efficacy Study of the Rex Medical Vascular Sealing System
The objective of this trial is to demonstrate the safety and effectiveness of the Rex Medical Closer Vascular Sealing System in sealing femoral arterial access sites.
- Trial name
- Closer (NCT02136004)
- Testing
- Closer VSS
- Where
- 12 sites in United States
- Volunteers
- 220 people
- Sponsor
- Rex Medical
Wounds and Injuries, Compartment Syndrome
Closure of Fasciotomy Wounds: A Prospective, Observational Study of a Continuous External Tissue Expander
Fasciotomy wounds are rarely able to be closed at the time of index surgery. They often require multiple returns to surgery for closure, and occasionally require skin grafting (i.e. they are never completely closed).
- Trial name
- NCT01171534
- Testing
- DermaClose fasciotomy closure, Vessel loop
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Missouri-Columbia
Pelvic Fractures, Acetabular Fractures
Role of Vacuum Assisted Closure (VAC) Device in Postoperative Management of Pelvic and Acetabular Fractures
The purpose of this research is to study the efficacy and cost effectiveness of the VAC device in comparison to traditional gauze wound dressing in pelvic, acetabular and hip fractures, specifically to see if there is a reduction…
- Conditions
- Pelvic Fractures, Acetabular Fractures, Hip Fractures
- Trial name
- NCT00635479
- Testing
- VAC device, Gauze dressing
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Missouri-Columbia
Breast Ptosis, Obesity
Evaluation of Dermal Closure With an Absorbable Barbed Suture as Compared to a Conventional Absorbable Suture
The objective of this study is to evaluate the use of an absorbable barbed suture as compared to a conventional absorbable suture when used for dermal closure during certain body contouring procedures.
- Trial name
- NCT00959374
- Testing
- V-Loc 180/90 Wound Closure Device, 3-0 Monocryl Absorbable Sutures
- Where
- 8 sites in United States, Germany
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Operative Time, Wound Heal
Subcuticular Absorbable Staples Versus Conventional Skin Closure in Women Undergoing Cesarean Delivery
Despite the high numbers of cesareans being performed, scientific evidence behind which surgical techniques are best remains uncertain.
- Trial name
- NCT05112640
- Testing
- INSORB: subcuticular stapling device, Subcuticular monocryl suture manufactured by Ethicon
- Where
- United States
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Open Abdomen
ABRA Abdominal Closure System in Open Abdomen Management
For the last 20 to 30 years, damage control laparotomy and decompressive laparotomy have emerged as part of the armamentariums for treatment of complex abdominal trauma, abdominal compartment syndrome, and critically ill surgical…
- Trial name
- ABRA (NCT00754156)
- Testing
- ABRA Abdominal Closure System, V.A.C. Therapy, KCI ABThera
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Anna Rockich
Linear Cutaneous Wound
Effectiveness of Embrace Scar Therapy Device After Cutaneous Wound Closure
The purpose of this study is to determine whether the use of the embrace device after repair of linear cutaneous surgery wounds improves scar cosmesis.
- Trial name
- NCT03294863
- Testing
- Embrace Scar Therapy Device, Standard of Care
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- University of California, Davis
Macromastia
Study of Prineo (Dermabond Protape) Versus Sutures in Breast Procedures
This is a prospective, controlled, randomized, multi-center clinical study of up to 80 patients with full thickness surgical incisions associated with bi-lateral breast procedures.
- Trial name
- NCT00558246
- Testing
- Dermabond Protape (Prineo), Suture
- Where
- 5 sites in Belgium, Germany and 2 more
- Volunteers
- 79 people
- Sponsor
- Ethicon, Inc.
Wounds and Injuries, Lacerations
A Clinical Study to Compare MAR-CUTIS With Dermabond Advanced
This was a randomized, open-label, multicenter, comparator-controlled clinical study to compare MAR-CUTIS with Dermabond Advanced in closure of surgical incisions and lacerations less than or equal to (<=)15 centimeter (cm).
- Conditions
- Wounds and Injuries, Lacerations, Surgical Incision
- Trial name
- NCT03688880
- Testing
- MAR-CUTIS, Dermabond Advanced
- Where
- 19 sites in France, Germany and 2 more
- Volunteers
- 107 people
- Sponsor
- Grünenthal GmbH
Fracture of Calcaneus, Pilon or Tibial Plateau
Vacuum Assisted Closure as a Treatment for Soft Tissue Injuries
This project is designed as a prospective, randomized, comparative study evaluating the use of a negative pressure vacuum device in treating soft tissue injuries and the surgical incision following open reduction and internal…
- Trial name
- VAC-ST (NCT00582998)
- Testing
- Standard Wound Dressing, Vacuum Assisted Closure Device
- Where
- United States
- Volunteers
- 249 people
- Sponsor
- University of Alabama at Birmingham
Surgical Wound, Shoulder Arthritis
Dermabond PRINEO for Total Shoulder Arthroplasty
This is a research study to find out whether wound closure (the process of closing the surgical wound after the procedure is complete) with Dermabond PRINEO Skin Closure System (PRINEO) will be faster and improve wound healing…
- Conditions
- Surgical Wound, Shoulder Arthritis, Surgical Incision
- Trial name
- NCT03860181
- Testing
- Subcuticular Sutures - Surgeon 1, Metal Staples - Surgeon 2, PRINEO - Surgeon 1
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Medical University of South Carolina