Clinical trials: Wound Closure Technique
Cesarean Section, Wound Dehiscence
A New Technique for Uterine Incision Closure at The Time of Cesarean Section: Does it Make a Difference
The purpose of this study was to compare the short term operative outcomes of three different surgical techniques for uterine incision closure during cesarean section (CS).
- Trial name
- NCT04681378
- Testing
- double layer step up-step down technique
- Volunteers
- 120 people
- Sponsor
- Menoufia University
Total Knee Arthroplasty
Perfusion Assessment of Wound Closure Techniques in Primary Total Knee Arthroplasty
This study will assess which of the three most common methods of wound closure in primary total knee arthroplasty (staples, interrupted vertical mattress, or running subcuticular suture) provide the best wound vascular perfusion.
- Trial name
- NCT01924403
- Testing
- Staple Closure, Vertical Mattress Closure, Running Subcuticular Closure
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Wound Closure Techniques
Undermining During Cutaneous Wound Closure
The purpose of this study is to determine whether undermining during cutaneous surgery improves scar cosmesis compared to wound closure without undermining.
- Trial name
- NCT02289859
- Testing
- Wound Closure with Undermining, Wound Closure without Undermining
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Wound Complication
Comparing Wound Complications After Elective Abdominal Surgery Using Two Closure Techniques
Wound complications, increased hospital stays and post-operative morbidity are all common following abdominal surgery. Abdominal closure complications are strongly associated with the closure technique and material used.
- Trial name
- COFACTOR (NCT03527433)
- Testing
- New closure technique
- Where
- Lebanon
- Volunteers
- 274 people
- Sponsor
- American University of Beirut Medical Center
Injury of Abdominal Wall
Effect of Stitch Technique on the Occurrence of Incisional Hernia After Abdominal Wall Closure
The major long term complication of abdominal wall closure after a median laparotomy is the development of an incisional hernia.
- Trial name
- ESTOIH (NCT01965249)
- Testing
- Long stitch, Short Stitch
- Where
- 9 sites in Austria, Germany
- Volunteers
- 425 people
- Sponsor
- Aesculap AG
Dehiscence of Laparotomy Wound, Surgical Wound Infection
Short Stitch Monomax®
A number of studies identifies abdominal hernia as the most frequent postoperative complication following laparotomy with percentages of 9-20% - depending on duration of follow-up.
- Trial name
- Short-Stitch (NCT01938222)
- Testing
- Short Stitch
- Where
- Germany
- Volunteers
- 351 people
- Sponsor
- Diakonie-Klinikum Schwäbisch Hall gGmbH
Laparotomy, Incisional Hernia
Clinical Performance and Safety of Suture-TOOL
The goal of this single arm intervention study is to investigate the safety and performance of a suturing device for closure of the midline incision after open abdominal surgery.
- Conditions
- Laparotomy, Incisional Hernia, Wound Infection, Closure Technique
- Trial name
- NCT05695157
- Testing
- Suture-TOOL
- Where
- Sweden
- Volunteers
- 38 people
- Sponsor
- Suturion AB
Stoma Reversal Procedure
Comparison of Outcome of Purse-string Versus Conventional Linear Wound Closure Techniques in Patients Undergoing Stoma Reversal
To compare outcomes of purse-string skin closure and conventional linear skin closure techniques in patients undergoing stoma reversal
- Trial name
- NCT07605403
- Testing
- Purse-string wound closure, Conventional linear wound closure
- Where
- Pakistan
- Volunteers
- 108 people
- Sponsor
- Children Hospital Faisalabad
Spinal Injuries
Wound Closure Techniques in Primary Spine Surgery
The Researchers are trying to determine if there is a difference in blood flow around a wound site when comparing three different types of wound closure techniques.
- Trial name
- NCT04396613
- Testing
- Closure technique
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Surgical Site Infection (SSI), Ileostomy Closure
Linear Versus Purse String Skin Closure at Loop Ileostomy Reversal.
This study is a randomized controlled trial designed to compare two commonly used skin closure techniques-linear closure and purse-string closure-after loop ileostomy reversal surgery.
- Conditions
- Surgical Site Infection (SSI), Ileostomy Closure, Surgical Technique Comparison
- Trial name
- NCT07573423
- Testing
- Linear Skin Closure, Purse-String Skin Closure
- Where
- Pakistan
- Volunteers
- 252 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar
Gynecologic Cancers, Surgical Wound Closure Techniques
Effect of Skin Closure Techniques on Body Image in Women Undergoing Gynecologic Surgery
This randomized clinical trial investigates the impact of two different skin closure techniques on body image and mood in women undergoing surgery for gynecologic cancers.
- Conditions
- Gynecologic Cancers, Surgical Wound Closure Techniques, Body Image
- Trial name
- BISGO (NCT07327125)
- Testing
- Continuous Subcuticular Suture, Interrupted Skin Closure
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Suture, Suture Dermatologic
Effect of Petrolatum Coating on Fast-absorbing Gut Suture
This study is designed to evaluate the effect of using petrolatum to coat gut suture. This coating is commonly performed to make the suture more easy to handle; however, it was unknown if it affects the absorption rate of the…
- Conditions
- Suture, Suture Dermatologic, Mohs Micrographic Surgery, Suture Techniques
- Trial name
- NCT07127029
- Testing
- Petrolatum coating of fast-absorbing gut suture
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- San Antonio Uniformed Services Health Education Consortium
Surgical Wound Closure Technique
Evaluation of Aesthetic Surgical Wound Closure by a Single Layer in Comparison With Traditional Multi-layer Closure
the study is comparing the results of aesthetic surgery wound closure by a single layer versus the traditional multi-layer closure as regards the wound healing time, local wound complications, and the scar formed.
- Trial name
- NCT05166681
- Testing
- surgical wound suturing
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Abouqir General Hospital
Open Abdomen, Temporary Abdominal Closure
Randomized Pilot Study Comparing Two Vacuum-wound-dressings for Open Abdomen Treatment
The primary purpose of the study is to determine whether two vacuum-wound-dressing techniques (the so called "abdominal dressing" versus "vacuum-pack-technique") are equally effective in the treatment of open abdomen.
- Trial name
- ABDOVAC (NCT00834314)
- Testing
- Vacuum-Pack-technique for temporary abdominal closure, Abdominal-dressing-technique for temporary abdominal closure
- Where
- Germany
- Volunteers
- 3 people
- Sponsor
- Universitätsmedizin Mannheim
Tonsillectomy, Children
Closure Method Study Following Tonsillectomy in Children
This is a children's study evaluating the effects of a tonsillectomy with tonsillar fossae closure compared to without closure of the operative wound.
- Trial name
- NCT00730340
- Testing
- Closure of the Tonsillar Fossa, Tonsillectomy with open fossa
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Oklahoma
Appendicitis, Surgical Wound Infection
Primary Versus Delayed Wound Closure in Complicated Appendectomy (The HIEDI-Yemen Trial)
The goal of this clinical trial is to compare primary wound closure (PC) versus delayed primary closure (DPC) after standardized wound decontamination using the High-Efficiency Incision and Drainage with Irrigation (HIEDI)…
- Conditions
- Appendicitis, Surgical Wound Infection, Postoperative Complications, Wound Healing
- Trial name
- HIEDI-Yemen (NCT07688109)
- Testing
- Primary Closure with HIEDI, Delayed Primary Closure with HIEDI
- Where
- 3 sites in Yemen
- Volunteers
- 200 people
- Sponsor
- Sana'a University
Pterygium
Alcohol 20% for Separation of Pterygium and Comparison of Different Wound Closure Methods
Purpose of this study is to evaluate efficiency and safety of Alcohol 20% for peeling pterygium and to compare 3 different methods of operative wound closure: Bare sclera, Sliding flap, Amniotic membrane + biological glue
- Trial name
- NCT00704977
- Testing
- pterygium surgery using alcohol 20% for tissue separation and bare sclera as wound closure technique
- Where
- 2 sites in Israel
- Volunteers
- 150 people
- Sponsor
- Soroka University Medical Center
Wound Closure Techniques
Use of 2-octylcyanoacrylate (Dermabond) Versus 5-0 Fast Absorbing Gut During Cutaneous Wound Closure
The purpose of this study is to determine whether the use of 2-octylcyanoacrylate during repair of linear cutaneous surgery wounds improves scar cosmesis compared to wound closure with 5-0 fast absorbing gut.
- Trial name
- NCT02547077
- Testing
- Wound Closure with 2-octylcyanoacrylate, Wound Closure with 5-0 Fast Absorbing Gut Sutures
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Cesarean Section
Effect of Subcutaneous Tissue Closure on Wound Complications
Only a small number of research studies evaluated the impact of various subcutaneous tissue and skin closure methods at cesarean section.
- Trial name
- NCT03354078
- Testing
- interrupted sutures, continous sutures
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Postoperative Wound Infection
Wick vs. No Wick: Does Method of Closure Affect Rate of Wound Infection?
Countless children undergo surgery annually for management of what clinicians consider to be a "dirty wound". One frequently encountered example is the ostomy reversal.
- Trial name
- NCT01691352
- Testing
- Wick dressing, No Wick
- Where
- United States
- Sponsor
- Children's Healthcare of Atlanta