Clinical trials: Wound Dehiscence, open to volunteers
Cesarean Section, Surgical Wound Infection
Timing of Cesarean Wound Dressing Removal on Wound Healing in Women With BMI ≥ 30 kg/m²
Cesarean delivery is one of the most common surgical procedures in obstetric care. Women with obesity (body mass index [BMI] of 30 kg/m² or higher) are at increased risk for postoperative wound complications, including surgical…
- Conditions
- Cesarean Section, Surgical Wound Infection, Wound Healing, Obesity
- Trial name
- NCT07846930
- Volunteers
- 726 people
- Sponsor
- Assiut University
Diabetic Foot Ulcer (DFU), Pressure Ulcer (PU)
PAW-Hydrogel for Chronic Wound Healing
The goal of this randomized controlled trial is to evaluate the efficacy and safety of a novel hydrogel made of Carbopol® 940 functionalized with Plasma-Activated Water (PAW) in patients with chronic wounds (diabetic foot ulcers…
- Conditions
- Diabetic Foot Ulcer (DFU), Pressure Ulcer (PU), Wound Dehiscence, Venous Leg Ulcer
- Trial name
- NCT07541196
- Testing
- PAW-Functionalized Carbopol® 940 Hydrogel, Standard Advanced Wound Care
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- Benjamín Gonzalo Rodríguez Méndez
Wound Dehiscence, Surgical
The Comparison of Interrupted Modified Smead-Jones Versus Conventional Continuous Suturing Technique for Closure of Rectus Sheath in Patients Undergoing Laparotomy for Hollow Viscus Perforation.
After taking approval from Board of Studies, IRB \& ASRB of KEMU, 108 patients fulfilling inclusion criteria will be admitted in Department of General Surgery, East Surgical Ward, Mayo Hospital Lahore through Emergency…
- Trial name
- Farrukh 24 (NCT06697067)
- Testing
- modified smead jones, conventional comtinuous suture techniques
- Where
- Pakistan
- Volunteers
- 108 people
- Sponsor
- King Edward Medical University
Insufficient Bone Volume Prior to Implant Surgery
The Tooth Collar Technique
The aim of this study is to evaluate wound healing after the application of the Tooth Collar Technique (TCT) for bone augmentation in the upper or lower jaw.
- Trial name
- TCTechnique (NCT07753525)
- Testing
- Tooth Collar Technique
- Where
- 4 sites in Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cesarean Section; Complications, Wound, Dehiscence
Effect of Bioptron Light Therapy on Wound Healing After Caesarean Section
The purpose of this study is to investigate the effect of Bioptron light therapy on wound healing after caesarean section.
- Trial name
- NCT07693478
- Testing
- Standard Postoperative Medical Care, Bioptron Light Therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Cesarean Section, Surgical Site Infection
Steri-Strip Application Versus Standard Wound Closure for Cesarean Section Incisions
This study is evaluating whether Steri-Strips® provide additional benefits when used after cesarean section (C-section) surgery.
- Conditions
- Cesarean Section, Surgical Site Infection, Wound Dehiscence, Seroma
- Trial name
- STRIP-CS (NCT07686913)
- Testing
- Steri-Strip™ Skin Closures, Standard Cesarean Wound Closure
- Where
- United States
- Volunteers
- 610 people
- Sponsor
- Riverside University Health System Medical Center
Cerebral Palsy
Knotless Versus Conventional Sutures for Wound Closure in Cerebral Palsy Multilevel Surgery
This study compares two standard ways of closing surgical incisions in children and adults with cerebral palsy who are having multilevel surgery on both legs (single-event multilevel surgery, or SEMLS).
- Trial name
- NCT07880197
- Testing
- Knotless barbed suture, Conventional suture
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Los Angeles
Fracture of Tibia, Wound Heal
Incisional Negative Pressure Wound Therapy to Reduce Infection and Complications in High-Risk Fractures
This is a multi-center, pragmatic, parallel arm randomized controlled trial (RCT) of 352 patients with high-risk open or closed tibial plateau fracture, high-risk open or closed tibial pilon fracture, or open tibial shaft…
- Conditions
- Fracture of Tibia, Wound Heal, Infected Wound, Wound Complication
- Trial name
- iVAC (NCT06337292)
- Testing
- Incisional Negative Pressure Wound Therapy (NPWT)
- Where
- 6 sites in United States
- Volunteers
- 352 people
- Sponsor
- Major Extremity Trauma Research Consortium
Pelvic Floor Dysfunction, Perineal Laceration
Perineal Protection Device for Reducing Perineal Trauma During Vaginal Delivery in First-time Mothers: a Multicenter Randomized Controlled Trial
The goal of this clinical trial is to determine whether using a soft perineal protection device (BabySlide®) in addition to standard manual perineal support during vaginal delivery can reduce the risk of perineal trauma in…
- Conditions
- Pelvic Floor Dysfunction, Perineal Laceration, Wound Dehiscence, Anal Incontinence
- Trial name
- PeriPROTECT (NCT07862660)
- Testing
- Perineal protection device, BabySlide, Standard manual perineal support
- Where
- Sweden
- Volunteers
- 4,226 people
- Sponsor
- Region Skane
Wound Healing, Wound Healing Complication
Association Between Female Hormonal Profile and Wound Healing
The goal of this observational study is to assess the relationship between female hormonal status and postoperative wound healing in reduction mammaplasty. The main questions it aims to answer are: 1.
- Conditions
- Wound Healing, Wound Healing Complication, Estradiol
- Trial name
- FEMHEAL (NCT07724145)
- Where
- Switzerland
- Volunteers
- 84 people
- Sponsor
- University Hospital, Geneva
Laparotomy, Dehiscence Wound
Barbed Suture vs Non-Barbed Closure for Emergency Exploratory Laparotomy RCT
This randomized control trial aims to compare the efficacy of triclosan-coated barbed suture (TCB) versus conventional non-barbed polydioxanone (PDS) suture in the closure of the abdominal fascia after emergency exploratory…
- Conditions
- Laparotomy, Dehiscence Wound, Surgical Site Infections, Trauma Abdomen
- Trial name
- NCT06043414
- Testing
- triclosan-coated barbed suture, triclosan-coated non-barbed suture, Non-coated non-barbed suture
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Southern California
Pilonidal Sinus Disorder
Factors Affecting Wound Dehiscence in Pilonidal Sinus Surgery (ORIPIS)
The goal of this multicenter, prospective, observational study is to investigate factors associated with wound dehiscence following pilonidal sinus surgery.
- Trial name
- NCT07370714
- Testing
- No intervention (observational study)
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Ankara Etlik City Hospital
Surgical Site Infection (SSI), Wound Healing Complication
Prophylactic Use of ciNPWT in Gynecologic Laparotomy
This is a prospective, open-label, non-randomized interventional feasibility study with a nested qualitative analysis. The study exploratively verifies the feasibility of targeted prophylactic closed incision negative pressure…
- Conditions
- Surgical Site Infection (SSI), Wound Healing Complication, Seroma, Hematoma
- Trial name
- NCT07645547
- Testing
- closed incision negative pressure wound therapy (ciNPWT)
- Volunteers
- 30 people
- Sponsor
- University Hospital Hradec Kralove
Surgical Complication
The Effect of Local Application of Tranexamic Acid Versus Placebo on Postoperative Complications in Plastic Surgery
Study objective: This is a study to investigate whether applying the drug tranexamic acid (TXA) onto a surgical wound surface may affect the incidence of surgical complications such as re-bleeding needing intervention, wound…
- Trial name
- TRANOP (NCT06270407)
- Testing
- Tranexamic Acid 100 MG/ML, 0.9%sodium chloride
- Where
- 11 sites in Denmark, Finland and 1 more
- Volunteers
- 3,000 people
- Sponsor
- St. Olavs Hospital
Chronic Pain, Wound Dehiscence
Comparing Polyglactin vs Polypropylene Sutures for Rectus Sheath Closure
This randomized controlled trial aims to compare the outcomes of Polyglactin (Vicryl) versus Polypropylene (Prolene) sutures for rectus sheath closure in patients undergoing midline laparotomy.
- Conditions
- Chronic Pain, Wound Dehiscence, Surgical Site Infection (SSI), Incisional Hernia
- Trial name
- PolySuture (NCT07280975)
- Testing
- Polyglactin 910 (Vicryl) Suture, Polypropylene (Prolene) Suture
- Where
- Pakistan
- Volunteers
- 156 people
- Sponsor
- Lady Reading Hospital, Pakistan
Cleft Lip, Cleft Palate +/- Lip
Comparative Study of Regional Nerve Blocks in Primary Cleft Palate Repair
This study will evaluate whether adding a suprazygomatic maxillary nerve block to the standard palatal nerve block improves pain control after cleft palate repair surgery in children.
- Conditions
- Cleft Lip, Cleft Palate +/- Lip, Pain Management, Wound Dehiscence, Surgical
- Trial name
- NCT07892963
- Testing
- Palatal Nerve Block, Suprazygomatic Maxillary Nerve Block
- Volunteers
- 144 people
- Sponsor
- Children's National Research Institute
Wound Breakdown, Breast Reduction
CO2Lift and T-Junction Breakdown Rates Evaluation After Breast Reduction Surgery Pilot Trial
The goal of this pilot study is to determine the feasibility of a larger randomized controlled trial evaluating CO₂Lift® Pro Carboxy Gel to reduce wound breakdown after bilateral breast reduction in adult female patients…
- Conditions
- Wound Breakdown, Breast Reduction, Surgical Wound, Breast Surgery
- Trial name
- CO2-BREAST (NCT07408960)
- Testing
- Carboxygel, Vaseline
- Volunteers
- 10 people
- Sponsor
- University of Calgary
Diabetic Foot Ulcer, Venous Leg Ulcer
Real World Evidence with the Debritom+ TM Novel Micro Water Jet Technology At a Single Wound Center
Prospective, single-blinded, single-center, parallel group, randomized controlled trial (RCT) to assess rate and frequency of wound healing and associated financial savings, when using Medaxis debritom+ versus standard of care as…
- Conditions
- Diabetic Foot Ulcer, Venous Leg Ulcer, Surgical Wound Dehiscence, Traumatic Wounds
- Trial name
- EVIDENT (NCT04920253)
- Testing
- Study Device Debridement, SOC Debridement
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Medaxis, LLC
Dehiscence Wound
Efficacy Evaluation of ActiGraft in Secondary Closure of Abdominal Surgical Wound Dehiscence
This is a prospective, single arm study, consisting of 20 women with abdominal surgical wound dehiscence that requires secondary closure.
- Trial name
- NCT04899466
- Testing
- ActiGraft
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- RedDress Ltd.
Total Laryngectomy
Early Feeding TL Trial
This is a randomized, single-center phase 2 study comparing early versus delayed oral feeding after total laryngectomy. Dysphagia-related outcomes will be assessed using the MDADI preoperatively, and on postoperative days 14 (±7)…
- Trial name
- NCT07919821
- Testing
- oral intake
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Florida