Clinical trials: Wound Healing
Osteochondral Defect of Talus
Ten Years Follow-up After the Arthroscopic Repair of Osteochondral Lesions of the Talus Via Autologous Matrix-induced Chondrogenesis (AMIC)
This clinical study evaluates the long-term, ten-year clinical and functional outcomes of patients who underwent arthroscopic repair of osteochondral lesions of the talus (OLT) using the autologous matrix-induced chondrogenesis…
- Trial name
- AMIC10Y (NCT07725770)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Bone Fracture
Digital Three-dimensional Imaging Models for Repair of Complex Long Bone Fractures
To verify whether digital three-dimensional model-assisted internal fixation can obtain better effects in the repair of complex long bone fractures compared with conventional internal fixation.
- Trial name
- NCT02964754
- Testing
- CT scan for internal fixation, conventional internal fixation
- Volunteers
- 63 people
- Sponsor
- Qinghai University
Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE)
Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)
This international study, organized by Healing Hope International, is an observational registry designed to collect real-world data on participants living with chronic hypoxic ischemic encephalopathy (HIE) who receive an emerging…
- Conditions
- Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE), Hypoxic Ischaemic Encephalopathy Due to Cardiac Arrest, Hypoxic Ischemic Encephalopathy of Newborn
- Trial name
- GEN-HOPE (NCT07264166)
- Where
- Mexico
- Volunteers
- 25 people
- Sponsor
- Healing Hope International
Rotator Cuff Tears
The Impact of Cervical Radiculopathy on Functionality in Patients Undergoing Rotator Cuff Repair
The aim of the study is to evaluate the impact of cervical radiculopathy on functional status and quality of life outcomes in patients who have undergone rotator cuff repair, comparing the group with a history of cervical…
- Trial name
- NCT07001566
- Testing
- There was no intervention. Only assessment procedure will be performed.
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Biruni University
Aorta Aneurysm
Graft Thrombosis After Endovascular Aortic Repair - a Single Center Experience With the Cook Zenith Alpha Spiral-Z®
The purpose of this study is to assess the extent of thrombosis in the Zenith Alpha Spiral-Z® stent graft.
- Trial name
- NCT04564560
- Testing
- Endovascular aortic repair with Zenith Alpha Spiral-Z®
- Where
- Norway
- Volunteers
- 161 people
- Sponsor
- St. Olavs Hospital
Burns, Burn Wound
Effect of Propolis Application on Burn Healing
This experimental study will be carried out at Ege University Laboratory Animals Application and Research Center to identify the efficacy of 10% propolis and 15% propolis on wound healing in a second-degree superficial burn…
- Trial name
- NCT04277182
- Testing
- burn wound dressing
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Mitral Regurgitation, Mitral Insufficiency
5-Year Follow-Up Safety and Performance Evaluation of the Medtentia Annuloplasty Ring in Adults
Single-center clinical investigation is to evaluate long-term safety and performance of the Medtentia Annuloplasty Ring (MAR) in 11 patients who underwent successful mitral valve (MV) surgery using Medtentia's MAR system in…
- Trial name
- NCT04161079
- Testing
- Medtentia Annuloplasty Ring (MAR)
- Where
- Finland
- Volunteers
- 12 people
- Sponsor
- Medtentia International Ltd Oy
Anterior Cruciate Ligament Injury
Acute Anterior Cruciate Ligament Rupture; RecOnsTruction Or Repair?
To investigate the hypothesis that suture repair of a ruptured vkb, combined with a dynamic intraligamentary stabilization and microfracture of the femoral notch, results in at least equal effectiveness compared with an ACL…
- Trial name
- ROTOR (NCT02310854)
- Testing
- ACL Repair, ACL reconstruction
- Where
- Netherlands
- Volunteers
- 48 people
- Sponsor
- Orthopedisch Centrum Oost Nederland
Fanconi Anemia
MRI as Noninvasive Innovative Approach in Detection and Monitoring of Malignant Oral Lesions in Fanconi Anemia Patients
This study being done to learn more about the use of medical Magnetic Resonance Imaging (mMRI) and dedicated dental MRI (ddMRI) as a non-invasive diagnosing tool when evaluating potential oral cancerous and precancerous lesions…
- Trial name
- NCT07649031
- Testing
- MRIs
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Minnesota
Diabetic Foot Ulcer (DFU), Venous Leg Ulcer (VLU)
Evaluation of the Safety and Efficacy of Dehydrated Human Placenta Tissue (dHPT) for Wound Healing
The retrospective trial is observational, intended to stand alone, complement and integrate data collected in ongoing clinical studies to aid in establishing payor coverage in the United States (U.S.) for Cellution Biologics…
- Conditions
- Diabetic Foot Ulcer (DFU), Venous Leg Ulcer (VLU), Pressure Ulcer (PU)
- Trial name
- RETRO-PLAST (NCT07375160)
- Testing
- dHPT, AIC
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Cellution Biologics
Inguinal Hernia, Pain
SEMPERFLO* Pain Management System in Inguinal Hernia Repair
This study will compare the clinical performance of the SEMPERFLO* Pain Management System with another commercial pain relief system using 0.5% bupivacaine following unilateral, open, inguinal hernia repair procedures. *Trademark
- Trial name
- NCT00423241
- Testing
- SEMPERFLO Pain Management System, ON-Q PainBuster Post-Op Pain Relief System
- Where
- 6 sites in United States
- Volunteers
- 7 people
- Sponsor
- Ethicon, Inc.
Intrapartum Hemorrhage
Exteriorization Versus Non-exteriorization of the Uterus During Repair of Uterine Incision in a Repeated Cesarean Section
Cesarean section is one of the most frequently performed major operations worldwide. It accounts for between 1% and 70% of deliveries depending on the facilities or country assessed.
- Trial name
- NCT03009994
- Testing
- Repair of uterine incision, Exteriorization of the uterus, Non exteriorization of the uterus
- Where
- Egypt
- Volunteers
- 1,024 people
- Sponsor
- Assiut University
Gingival Recession
Platelet Rich Fibrin in the Treatment of Palatal Wounds
In this study it will be investigated the usefulness of Platelet-Rich Fibrin (PRF) on in the epithelialized connective tissue graft palatal donor site healing acceleration and in the patient's morbidity reduction.
- Trial name
- NCT02438046
- Testing
- Palatal wound bandage
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Wound
Doubleblinded RCT of the Omnilux on Lower Extremity Surgical Wounds Left to Heal by Second Intention
The goal of the study is to evaluate the effectiveness of the light-emitting diode (LED) in promoting healing of the wound on lower leg as a result of surgery.
- Trial name
- NCT02383056
- Testing
- Omnilux
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Miami
Periodontal Regeneration, Wound Healing
Effects of Standard PRP and Extracellular Vesicle-Enriched PRP on Human Gingival Fibroblasts
The goal of this study is to compare the biological effects of two blood-derived products, standard platelet-rich plasma (PRP) and extracellular vesicle-enriched PRP (EV-enriched PRP), on human gingival (gum) fibroblasts, the…
- Conditions
- Periodontal Regeneration, Wound Healing, Fibroblast
- Trial name
- NCT07855822
- Where
- Turkey (Türkiye)
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Inonu University
Inguinal Hernia,Laparoscopy,Extra-peritoneal
A Comparative Study on Trans-umbilical Single-port Laparoscopic Extra-peritoneal Approach Versus Conventional Repair for Inguinal Hernia in Children
Inguinal hernia is a common disease in children. Treatment of this disease by laparoscopic high ligation of the hernia sac has been accepted by domestic and foreign scholars.
- Trial name
- NCT02960529
- Testing
- extra-peritoneal high ligation of hernia, intraabdominal high ligation of hernia
- Where
- China
- Volunteers
- 300 people
- Sponsor
- zebing Zheng
Cleft Palate Repair
Double Blind Randomized Study Into the Efficacy of Codeine Phosphate Analgesia After Cleft Palate Repair in Infants
This study examines the analgesic efficacy of codeine phosphate. It is compared to placebo in infants receiving morphine after surgery. Codeine may be effective enough to make morphine unnecessary.
- Trial name
- NCT00386269
- Testing
- Codeine Phosphate Analgesia
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Institute of Child Health
Defect of Articular Cartilage
Mesenchymal Stem Cells in a Clinical Trial to Heal Articular Cartilage Defects
The purpose of this study is to: Compare the treatment efficacy of autologous mesenchymal stem cells (Mesenchymal Stem Cells) versus chondrocytes implanted in a commercial available scaffold in a human clinical trial.
- Trial name
- NCT00885729
- Testing
- stem cells, Chondrocytes, Rehabilitation program
- Where
- Norway
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Shoulder Instability, Shoulder Dislocation or Subluxation
Multifactorial Approach Training for Anterior Shoulder Instability in Patients Undergoing Arthroscopic Bankart Repair
This study will compare functional outcomes after an arthroscopic Bankart repair between patients that underwent conventional arthroscopic Bankart repair rehabilitation, following the American Society of Shoulder and Elbow…
- Conditions
- Shoulder Instability, Shoulder Dislocation or Subluxation, Fear of Movement, Kinesiophobia
- Trial name
- MATASI (NCT06157229)
- Testing
- MAT, CABRR
- Volunteers
- 100 people
- Sponsor
- Spaarne Gasthuis
Mitral Regurgitation, Mitral Valve Disease
Multicenter Post-Market Observational Registry of the NeoChord Artificial Chordae Delivery System
The objective of this study is to evaluate the 5-year outcomes of participants with degenerative mitral valve disease treated with the NeoChord Artificial Chordae System, Model DS1000 in a post-market setting.
- Conditions
- Mitral Regurgitation, Mitral Valve Disease, Mitral Valve Insufficiency, Mitral Valve Prolapse
- Trial name
- AcChord (NCT04190602)
- Testing
- NeoChord Artificial Chordae Delivery System, Model DS1000
- Where
- 5 sites in Germany, Greece and 1 more
- Volunteers
- 500 people
- Sponsor
- NeoChord