Clinical trials: Wound Infection
HIV Infections, Alcohol Drinking
Boston Alcohol Research Collaboration on HIV/AIDS (ARCH) Cohort: The 4F Study
The purpose of this study is to follow a cohort of HIV-infected adults who have alcohol and/or drug use to: 1) test the associations between alcohol (and illicit drugs and polypharmacy (multiple prescribed medications)) and falls…
- Conditions
- HIV Infections, Alcohol Drinking, Substance-Related Disorders, Bone Diseases
- Trial name
- NCT03414411
- Where
- United States
- Volunteers
- 251 people
- Sponsor
- Boston University
AI (Artificial Intelligence), Mammary Cancer
Experiment on the Use of Innovative Computer Vision Technologies for Analysis of Medical Images in the Moscow Healthcare System
It is planned to integrate various services based on computer vision technologies for analysis of the certain type of x-ray study into Moscow Unified Radiological Information Service (hereinafter referred to as URIS).
- Conditions
- AI (Artificial Intelligence), Mammary Cancer, Lung Cancer, X-Rays; Lesion
- Trial name
- NCT04489992
- Where
- Russia
- Volunteers
- 133,000 people, healthy volunteers welcome
- Sponsor
- Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
Infection Secondary to Surgical Procedure
Effect of Chlorhexidine Gluconate Hair Bath on the Development of Surgical Site Infection and Time to Discharge
One of the most important preventable complications occurring in the postoperative period is surgical site infections. Surgical site infections (SSI) are infections that occur in incisions, organs or organ spaces that occur after…
- Trial name
- NCT06763211
- Testing
- Chlorhexidine Hair Bath
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- HAVVA ÇOŞKUN
Cardiovascular Surgical Procedures, Arthroplasty, Replacement
Trial to Reduce Antimicrobial Prophylaxis Errors (TRAPE)
The specific aims are to determine the incidence of medication errors related to antimicrobial prophylaxis for cardiovascular surgery, joint replacement surgery, and hysterectomies across a heterogeneous sample of hospitals…
- Conditions
- Cardiovascular Surgical Procedures, Arthroplasty, Replacement, Hysterectomy
- Trial name
- NCT00114036
- Testing
- Quality improvement strategies
- Where
- 3 sites in United States
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Surgical Site Infections
Safety, Efficacy and Tolerability Study of up to 20 mL of DFA-02 in Patients Undergoing Abdominal Surgery
This is a randomized, blinded, placebo and standard of care controlled study of the efficacy of a novel antibiotic containing gel compared to placebo gel in preventing surgical site infection after abdominal surgery.
- Trial name
- NCT01888367
- Testing
- DFA-02 Antibiotic Gel
- Where
- 31 sites in United States
- Volunteers
- 445 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Fracture Non Union, Infection
Antibiotic Loaded Calcium Sulfate RCT
This is a multi-centered, prospective, randomized controlled trial comparing current standard of care for defect management to placement of antibiotic loaded Stimulan as a bone void filler in patients undergoing treatment of…
- Trial name
- NCT03875963
- Testing
- Antibiotic loaded bone filler
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
HIV/AIDS, Cardiovascular Risk Factors
Healing Our Hearts Minds and Bodies: CVD Reduction in Persons With HIV
"Healing our Minds and Bodies" (HHMB) uses a a hybrid type II effectiveness/implementation study design to increase both patient and organizational readiness to address trauma and CVD risk among African American and Latino…
- Conditions
- HIV/AIDS, Cardiovascular Risk Factors, Trauma, Psychological
- Trial name
- HHMB (NCT04025463)
- Testing
- HHMB
- Where
- 2 sites in United States
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Surgical Wound, Wound Dehiscence, Surgical
Prophylactic Negative Pressure Wound Therapy for High Risk Laparotomy Wounds. A Randomized Prospective Clinical Trial.
Negative pressure wound closure technique (NPWT) has been widely introduced in different clinical settings. Most of the studies report it as an effective and cost-effective method to treat complicated surgical wounds or even open…
- Conditions
- Surgical Wound, Wound Dehiscence, Surgical, Surgical Site Infection, Dehiscence of Internal Surgical Wound
- Trial name
- NCT03716687
- Testing
- Prophylactic negative pressure wound dressing after laparotomy
- Where
- Hungary
- Volunteers
- 100 people
- Sponsor
- St. Borbala Hospital
Systemic Inflammatory Response Syndrome, Sepsis
Impact of Vitamin D Supplementation on Hepcidin Levels and Transfusion Requirements in Surgical and Septic Patients
Acute inflammation induced by surgery and sepsis is complicated by the development of iron-restricted anemia due to the up-regulation of hepcidin.
- Conditions
- Systemic Inflammatory Response Syndrome, Sepsis, Surgical Injuries
- Trial name
- DEHEPTRA (NCT03001687)
- Testing
- enteral supplementation with vitamin D, blood collection 3mL
- Where
- Romania
- Volunteers
- 40 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Acute Kidney Injury, Severe Sepsis
Acute Kidney Injury in Septic Critically Ill Patients : Are Aminoglycosides Really Harmful?
The purpose of the present study is to determine whether administration of aminoglycosides in septic critically ill patient is a risk factor for acute kidney injury
- Trial name
- REAMICHOC (NCT01932814)
- Where
- France
- Volunteers
- 317 people
- Sponsor
- Université Victor Segalen Bordeaux 2
Surgical Site Infection
The Use of Ceftaroline as Surgical Prophylaxis in Surgery With Risk of MRSA Infection
The study is a randomized double-blinded study comparing ceftaroline to standard of care therapy with cefazolin and vancomycin as surgical prophylaxis for high risk orthopedic and cardiac surgeries.
- Trial name
- PREVTAROLINE (NCT02307006)
- Testing
- Ceftaroline, Cefazolin / Vancomycin
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- University of Cincinnati
Edema, Pain
Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema
The present study is designed to reveal effectiveness of hyaluronidase and dexamethasone on reduction of postoperative edema, pain, trismus, and infection.
- Conditions
- Edema, Pain, Trismus, Infection, Surgical Site
- Trial name
- NCT05466604
- Testing
- Hyaluronidase Injection mesomedica, Dexamethasone dekort
- Where
- 2 sites in Cyprus, Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Infection Secondary to Surgical Procedure
Antibiotic Prophylaxis in Gynecologic Laparoscopy
Laparoscopy is a surgical procedure indicated for most gynecological pathologies and presents numerous advantages over laparotomy, among them lower rates of surgical site infection and less comorbidity feverish.
- Trial name
- NCT01991834
- Testing
- gynecologic laparoscopy, Cefazolin
- Where
- 2 sites in Brazil
- Volunteers
- 114 people
- Sponsor
- Universidade do Vale do Sapucai
SARS-CoV-2 Infection, Acute Kidney Injury
Nicotinamide Riboside in SARS-CoV-2 (COVID-19) Patients for Renal Protection
An interventional clinical trial using oral nicotinamide riboside (NR) in hospitalized patients with COVID-19 infection and acute kidney injury to determine the effect of NR on whole blood nicotinamide adenine dinucleotide (NAD+)…
- Trial name
- NIRVANA (NCT04818216)
- Testing
- Nicotinamide riboside
- Where
- 4 sites in United States
- Volunteers
- 28 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Enterocolitis, Necrotizing, Bacteremia
Antibiotic "Dysbiosis" in Preterm Infants
Prolonged antibiotic use in preterm neonates has significant consequences on the developing intestinal microbiome, metabolome and host response, predisposing the neonate to various major morbidities, including necrotizing…
- Conditions
- Enterocolitis, Necrotizing, Bacteremia, Bronchopulmonary Dysplasia, Intraventricular Hemorrhage
- Trial name
- NCT02784821
- Testing
- Antibiotic, Gastric fluid, Breast milk
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- University of Florida
Surgical Site Infection, Bleeding
Mild Hypothermia Influence on Patient Outcome in Major Abdominal Surgery
This study investigate associations between mild hypothermia (patients' core temperature ≤ 36.0 degrees Celsius) and intra-operative blood loss and surgical site infections (SSI) in patients undergoing major abdominal surgery.
- Trial name
- NCT03112317
- Testing
- Prevention of hypothermia
- Where
- 2 sites in Norway
- Volunteers
- 3,059 people
- Sponsor
- Haukeland University Hospital
Dislocation, Infection
Fixation of Thoracic Epidurals Influencing Catheter-related Infections and Dislocation
Major interest in our investigation is to find out whether distinct fixation techniques influence catheter dislocation and/ or incidence of local inflammation.
- Conditions
- Dislocation, Infection, Line Colonisation, Line Insertion Site
- Trial name
- TDPAFD (NCT01402778)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Labour Pain, Cold Therapy
Effect of Intermittent Heat and Cold Therapy on Comfort During Labor
Summary of the Study Childbirth is one of the most significant and complex experiences in any mother's life. According to a study, labour pain ranges from mild to severe and is felt throughout the body, particularly in the lower…
- Conditions
- Labour Pain, Cold Therapy, Heat Therapy
- Trial name
- NCT06214585
- Testing
- Intermittent heat and cold versus heat-only therapy, Heat- only Therapy
- Where
- Nepal
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University, Nepal
Cesarean Section, Surgical Site Infection
Preoperative Application of Chlorhexidine to Reduce Infection With Cesarean Section After Labor
Surgical site infections (SSI) are the second most common cause of nosocomial infections accounting for 15% of all nosocomial infections among hospitalized patients and 38% of nosocomial infections in surgical patients.
- Conditions
- Cesarean Section, Surgical Site Infection, Nosocomial Infection
- Trial name
- PRACTICAL (NCT03423147)
- Testing
- 2% chlorhexidine gluconate cloth, 4% Chlorhexidine gluconate vaginal scrub
- Where
- United States
- Volunteers
- 319 people
- Sponsor
- Angela Bianco
Acute Lithiasic Cholecystitis Grade I or II, Symptoms Lasting for Less Than 5 Days
Place of Antibiotics in the Postoperative Acute Lithiasic Cholecystitis
Assess whether postoperative antibiotics after cholecystectomy for acute lithiasic cholecystitis little or moderately severe, is effective and therefore justified.
- Conditions
- Acute Lithiasic Cholecystitis Grade I or II, Symptoms Lasting for Less Than 5 Days, Required Cholecystectomy, Preoperative Amoxicillin Clavulanic Acid for at Most 5 Days
- Trial name
- ABCAL (NCT01015417)
- Testing
- Amoxicillin clavulanic acid, No medication
- Where
- 21 sites in France
- Volunteers
- 414 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
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