Clinical trials: Wound Infection,
Urolithiasis, Urologic Diseases
Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis
To investigate the effectiveness of percutaneous nephrostomy catheter placement versus retrograde double J catheter placement in patients with symptoms of obstructive kidney disease (with either infection and/or pain and/or…
- Conditions
- Urolithiasis, Urologic Diseases, Urinary Calculi, Urinary Obstruction
- Trial name
- STONE (NCT04594161)
- Testing
- Percutaneous Nephrostomy, Double J catheter
- Where
- Netherlands
- Volunteers
- 204 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Wound Infection
The Clinical Efficacy of Next Science Wound Gel (NXTSC) in the Healing of Chronic Wounds
Determine the effect on wound treatment outcomes using a novel antimicrobial wound gel (NXTSC) for the treatment of infected wounds as the sole topical treatment of microbial infection at the wound site.
- Trial name
- NCT02465073
- Testing
- NXTSC wound gel, NXTSC wound gel plus Standard of Care, Standard of Care Group
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Southwest Regional Wound Care Center
COVID-19, Myocardial Injury
Myocardial Injury and Quality of Life After COVID-19
In this observational study follow-up and dynamic observation will be conducted on the participants recovered from pneumonia caused by COVID-19.
- Conditions
- COVID-19, Myocardial Injury, Myocarditis Post Infection
- Trial name
- NCT04794062
- Where
- Russia
- Volunteers
- 119 people
- Sponsor
- Voronezh Regional Clinical Consultative and Diagnostic Center
Sepsis, Lung Injury
Inhalational Versus Intravenous Anesthesia on Postoperative Lung Injury in Septic Patients Undergoing Surgery
This randomized controlled trial will compare the effects of intraoperative inhalational anesthesia versus intravenous anesthesia on postoperative lung injury in septic patients undergoing surgery.
- Trial name
- NCT07601256
- Testing
- Inhalation Anesthesia, intravenous anesthesia
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Finger Injuries
Silicone Finger Cap ("Silikonfingerling")
Amputation injuries of the fingertip are common in all ages. For decades it is known that conservatively treated fingertips can regenerate skin and soft tissues to form a functionally and cosmetically excellent new fingertip.
- Trial name
- NCT03089060
- Testing
- Silicone Finger cap, Film Dressing
- Where
- Germany
- Volunteers
- 22 people
- Sponsor
- Orthopädie- und Rehatechnik Dresden GmbH
Wound, Wound Infection
The Use of Biochemical Analyzes to Monitor the Development of Wounds
Chronic wounds represent a growing challenge in medical care. Part 1: The aim of this part of the study was to collect wound swabs and to answer the question whether the rapid diagnostic tool using enzyme activities can display…
- Conditions
- Wound, Wound Infection, Wound Contamination, Diagnostic Techniques and Procedures
- Trial name
- NPWW (NCT04507724)
- Where
- Austria
- Volunteers
- 41 people
- Sponsor
- Qualizyme Diagnostics GmbH & Co KG
Osteoporosis, Fractures
Determination of Optimum Age for DXA Screening for Osteoporosis in HIV - The Probono 1 Study
The purpose of this study is to determine the bone mineral density in male and female patients with HIV infection according to age groups.
- Conditions
- Osteoporosis, Fractures, HIV Infection
- Trial name
- Probono1 (NCT01669954)
- Where
- United Kingdom
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- King's College London
Pancreatitis
The Development of Pancreatic Injury in the Course of Severe Acute Respiratory Syndrome Coronavirus 2 Infection
Although COVID-19 disease due to Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the respiratory tract, heart and coagulation system, symptoms of gastrointestinal system involvement such as abdominal pain…
- Trial name
- NCT04433754
- Testing
- biochemical analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Uşak University
Endometritis, Cesarean Section; Infection
Two-drug Antibiotic Prophylaxis in Scheduled Cesarean Deliveries
Cesarean deliveries are the most common surgical procedure performed in the United States. A significant decrease in cesarean delivery associated maternal morbidity has been achieved with preoperative prophylactic single-dose…
- Conditions
- Endometritis, Cesarean Section; Infection, Wound Infection
- Trial name
- NCT03960970
- Testing
- Azithromycin 500 mg, Mefoxin 2g
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- RWJ Barnabas Health at Jersey City Medical Center
Tumor, Fracture
Management of Bone Defects Around the Elbow
Background: Bone defects of the distal humerus require complex reconstructions, for which standard prostheses may be insufficient.
- Conditions
- Tumor, Fracture, Cancer
- Trial name
- NCT00873145
- Testing
- HMRS
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Colorectal Cancer, Wound Infection
Comparing PP and PVDF Meshes in Midline Laparotomy Closure for High-risk Colorectal Surgery. Impact on Incisional Hernia and Surgical Wound Infection.
In the latest guidelines for abdominal wall closure in emergency surgery published in the World Journal of Emergency Surgery (WJES) in 2023, no specific recommendations are made in this regard.
- Conditions
- Colorectal Cancer, Wound Infection, Hernia Incisional
- Trial name
- PROFIMESH (NCT06220045)
- Testing
- Polyvinylidene fluoride mesh, Prophylactic polypropylene mesh
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Covid19, Neurological Manifestations
Study of Morphological, Spectral and Metabolic Manifestations of Neurological Complications in Covid-19 Patients
Viral pandemics, such as HIV and SARS-Cov-V1, have shown that they can lead to acute and / or delayed neurological complications.
- Conditions
- Covid19, Neurological Manifestations, Brain Damage
- Trial name
- NSpectroCovid (NCT04546737)
- Testing
- Magnetic Resonance Spectroscopy (MRS).
- Where
- France
- Volunteers
- 21 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Post-laparoscopy Umbilical Port-site Wound Infection
The AVATAR Trial: Applying VAcuum To Accomplish Reduced Wound Infections
Postoperative pain and time taken to return to normal activities after laparoscopic surgery are significantly shorter. Wound infections still occur and contribute to prolonged hospital stays and morbidity.
- Trial name
- AVATAR (NCT01623427)
- Testing
- Application of vacuum, No vacuum
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Manitoba
Critical Illness, Intensive Care Patients
IMMUNOREA - Immunological and Inflammatory Determinants Associated With the Prognosis of Intensive Care Patients
This is a prospective observational physiopathological study aimed at evaluating the immunological and inflammatory determinants associated with the prognosis of patients admitted to intensive care units (ICU).
- Conditions
- Critical Illness, Intensive Care Patients, Critical Illness Requiring Intensive Care - Sepsis, Critical Illness Requiring Intensive Care - Acute Brain Injury
- Trial name
- IMMUNOREA (NCT07345169)
- Where
- France
- Volunteers
- 540 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sars-CoV2, Tear
SARS Cov-2 in Conjunctival Secretion in COVID-19 Patients
Observational study to evaluate the presence of SARS COV-2 in tears collected in COVID-19 patients in Lombardia region, northern Italy, and to correlate virus presence to concomitant systemic clinical conditions.
- Trial name
- NCT04402853
- Testing
- Tears swab
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Università degli Studi dell'Insubria
Lung Diseases, Lung Inflammation
Impact of Lidocaine Administration on Postoperative Complications During Lung Resection Surgery
The purpose of this study is to analyze the impact of the intravenous (IV) or paravertebral (PV) lidocaine administration during the intraoperative period of lung resection surgery on the appearance of postoperative…
- Conditions
- Lung Diseases, Lung Inflammation, Lung Injury, Acute, Postoperative Complications
- Trial name
- NCT03905837
- Testing
- Lidocaine, Remifentanil
- Where
- Spain
- Volunteers
- 156 people
- Sponsor
- Francisco Andres de la Gala
Sepsis, Shock
Studies of Blood DNA in Patients With Severe Infection DYNAMICS
Severe sepsis (ie. life-threatening infections) is triggered by harmful microorganisms or their toxins in the blood or tissues. These harmful agents damage the lining of blood vessels which can lead to inflammation, blood clot…
- Conditions
- Sepsis, Shock, Trauma
- Trial name
- DYNAMICS (NCT01355042)
- Where
- 6 sites in Canada
- Volunteers
- 792 people
- Sponsor
- Alison Fox-Robichaud
Substance Use Disorders, HIV Infections
Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People
This is a multi-phased study, funded through a National Institute on Drug Abuse (NIDA) K24 grant that aims to ultimately refine a virtual reality tool through qualitative and quantitative research targeting HIV and substance…
- Trial name
- NCT05816083
- Testing
- Virtual Reality Tool
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Wound Infection
Supplemental Oxygen Reduces Surgical Infection
Supplemental perioperative oxygen has been reported to halve or double the risk of surgical wound infection. We tested the hypothesis that supplemental oxygen reduces infection risk following colorectal surgery.
- Trial name
- NCT00235456
- Testing
- Perioperative supplemental oxygen, Standard oxygen
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- The Cleveland Clinic
Tuberculosis, Drug-Induced Liver Injury
A Pharamcogenomic Study for Isoniazid According to NAT2 Polymorphism Status
A clinical trial to investigate the appropriate dose of isoniazid according to NAT2 polymorphism status in Korean subjects
- Conditions
- Tuberculosis, Drug-Induced Liver Injury, Adverse Drug Event
- Trial name
- NCT03665402
- Testing
- Isoniazid
- Where
- South Korea
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital