Clinical trials: Wound Infection, Surgical
Surgical Site Infection
Comparison Of Outcome Of Antibiotic Coated Vicryl Vs Non-Coated Vicryl In Abdominal Fascial Closure After Laparotomy In Children
We are investigating outcome of antibiotic coated vicryl versus non coated vicryl in terms of rate of surgical site infection and lebgth of hospital stay in children after lalaprotomy for perforated viscera.
- Trial name
- NCT06129773
- Testing
- antibiotic coated vicryl used for fascial closure
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Muhammad Adeel Ashiq
Wound Infection
Abdominal Wall Closure With Triclosan-coated Suture (TCS09-10)
After open colo-rectal surgery the surgical site infection (SSI) is very high among abdominal surgeries. The goal of the investigators randomized, prospective, multicentric, internet-based study is to compare rate of SSI after…
- Trial name
- NCT01123616
- Testing
- abdominal wall closure
- Where
- Hungary
- Volunteers
- 1 people
- Sponsor
- University of Pecs
Surgical Site Infection
The Use of Ceftaroline as Surgical Prophylaxis in Surgery With Risk of MRSA Infection
The study is a randomized double-blinded study comparing ceftaroline to standard of care therapy with cefazolin and vancomycin as surgical prophylaxis for high risk orthopedic and cardiac surgeries.
- Trial name
- PREVTAROLINE (NCT02307006)
- Testing
- Ceftaroline, Cefazolin / Vancomycin
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- University of Cincinnati
Necrotizing Soft Tissue Infection, Necrotizing Fascitis
Prognosis and Treatment of Necrotizing Soft Tissue Infections: A Prospective Cohort Study
The investigators will analyze biomarkers related to the prognosis and treatment of necrotizing soft tissue infections (NSTI). The focus will be on whether certain endothelial and immune system biomarkers can function as markers…
- Conditions
- Necrotizing Soft Tissue Infection, Necrotizing Fascitis, Gas Gangrene, Fournier Gangrene
- Trial name
- ProTreat (NCT03147352)
- Testing
- Hyperbaric oxygen therapy
- Where
- Denmark
- Volunteers
- 260 people
- Sponsor
- Ole Hyldegaard
Surgical Infection, Cesarean Section Wound
Evaluation of Surgical Site Infection After Cesarean Section
This study aims to investigate surgical site monitoring after cesarean section using a mobile application currently being developed.
- Trial name
- NCT07205939
- Testing
- Mobile Application usage
- Where
- Turkey (Türkiye)
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Sibel Bulut Haklı
Surgical Site Infection
Number of Necessary Paints of Preoperative Skin Disinfection to Prevent Surgical Site Infections
This observational study investigates whether 3 paints are superior compared to 2 paints in reducing microbial skin counts in the disinfection area of cardiac and abdominal surgery patients.
- Trial name
- PAINTS (NCT03859375)
- Testing
- microbial skin counts in the disinfection area after paints of skin disinfectants
- Where
- Switzerland
- Volunteers
- 239 people
- Sponsor
- University Hospital, Basel, Switzerland
Sternal Wound Infection, Mediastinitis
Rapid Sternal Closure System (TALON)
The primary objective is to establish if the Rapid Sternal Closure System (RSCS) improves early postoperative recovery as manifested by decreased pain and improved pulmonary function.
- Trial name
- TALON (NCT00638014)
- Testing
- Rapid Sternal Closure System, Conventional wire closure
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Duke University
Surgical Wound, Surgical Wound Infection
Caesarean Wound Dressing Removal Study
An open labelled randomised trial on the timing of wound dressing removal for emergency caesarean delivery in labour.
- Conditions
- Surgical Wound, Surgical Wound Infection, Cesarean Section Complications
- Trial name
- Cesarean (NCT05458518)
- Testing
- Cesarean wound dressing removal
- Where
- Malaysia
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Hospital Kemaman
Hepatobiliary Surgery, Prophylactic Antibiotics
Prophylactic Antibiotics in Preventing Surgical Site Infection After Hepatobiliary Surgery in High-Resistant Settings
To analyse the efficacy of different preoperative prophylactic antimicrobial regimens for perioperative infection prevention in patients undergoing hepatobiliary surgery in a high antimicrobial resistance setting.
- Trial name
- PASH (NCT07620223)
- Testing
- Piperacillin-tazobactam
- Where
- China
- Volunteers
- 378 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Dry Socket, Wound Infection
Triclosan Toothpaste and Third Molar Surgery
Triclosan containing dentifrices are effective in the prevention of inflammatory complications following third molar surgery through reducing preoperative oral bacteria load.
- Trial name
- NCT01292343
- Testing
- Colgate Total Toothpaste, Colgate Regular Toothpaste
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Infection, Surgical Site
Povidone-Iodine and Ozonated Distilled Water Irrigation in the Management of Maxillofacial Space Infections
Maxillofacial space infections are among the most common infections encountered in oral and maxillofacial surgery and may progress to severe, life-threatening complications if not properly managed, making their treatment a…
- Trial name
- NCT07904143
- Testing
- Incision and drainage + Povidone-iodine irrigation, Incision and drainage + ozonated distilled
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Alexandria University
Surgical Site Infection
Wound Protector Dual-ring Alexis® in Pancreaticoduodenectomy
Surgical site infection (SSI) is a leading cause of preventable morbidity and mortality in North America and worldwide. This condition has consistently been reported to account for up to 25% of all healthcare-associated…
- Trial name
- PALEXIS (NCT03820648)
- Testing
- Alexis, Standard 3M™ Steri-Drape 2
- Where
- Italy
- Volunteers
- 212 people
- Sponsor
- Azienda Ospedaliera Universitaria Integrata Verona
Cardiovascular Disease, Surgical Site Infection
Innovative Sternal Closure Techniques: Evaluating STRATAFIX™ and DERMABOND™ for Reduced Complications in CABG Patients
The goal of this clinical trial is to learn if a new method of closing the breastbone after heart bypass surgery can improve healing and reduce complications in adults undergoing coronary artery bypass graft (CABG) surgery.
- Conditions
- Cardiovascular Disease, Surgical Site Infection, Superficial Sternal Wound Infection, Mediastinitis
- Trial name
- NCT07507409
- Testing
- Knotless Barbed Sutures, Mesh-based Topical Skin Adhesive
- Volunteers
- 401 people
- Sponsor
- Unity Health Toronto
Hernia, Wound Infection
Suture Techniques to Reduce the Incidence of The inCisional Hernia
The objective of the study is reduction of the incidence of the most frequent complication of abdominal surgery, incisional hernia.
- Conditions
- Hernia, Wound Infection, Burst Abdomen, Pain
- Trial name
- STITCH (NCT01132209)
- Testing
- Closure of the abdominal wall after midline incisions
- Where
- Netherlands
- Volunteers
- 576 people
- Sponsor
- Erasmus Medical Center
Achilles Tendon Repairs/Reconstructions, Pilon Fracture of Tibia
Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging.
Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Feasibility Study on Nitropaste Using Intraoperative SPY Imaging.
- Conditions
- Achilles Tendon Repairs/Reconstructions, Pilon Fracture of Tibia, Tibial Plateau Fracture, Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar)
- Trial name
- SPY NITROPASTE (NCT07004764)
- Testing
- Nitroglycerin Ointment 2%
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Johns Hopkins University
Surgical Site Infection
Perioperative Patient Skin Antiseptic Preparation Evaluation
This study will evaluate a new topical skin antiseptic perioperative preparation and the standard of care to determine efficacy on the rates of surgical site infections of surgical patients. Safety will also be assessed.
- Trial name
- NCT04756804
- Testing
- 70% v/v Isopropyl Alcohol Surgical Solution, 2%w/v Chlorhexidine Gluconate / 70% v/v Isopropyl Alcohol
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Abscess Soft Tissue, Methicillin-resistant Staphylococcus Aureus (MRSA) Infection
Randomized Controlled Trial of Antibiotics in the Management of Children With Community-Acquired Abscess
The purpose of this study is to better understand why children develop methicillin-resistant Staphylococcus aureus (MRSA) skin infections that require surgical drainage and whether antibiotics are helpful after the infection is…
- Conditions
- Abscess Soft Tissue, Methicillin-resistant Staphylococcus Aureus (MRSA) Infection, Skin Abscess
- Trial name
- NCT01498744
- Testing
- Oral Clindamycin
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Abscess, Skin Diseases, Infectious
Study of Wound Packing After Superficial Skin Abscess Drainage
Superficial skin and soft tissue abscess are frequently managed by opening them up with a procedure called "incision and drainage".
- Conditions
- Abscess, Skin Diseases, Infectious, Boils, Furuncle
- Trial name
- NCT00746109
- Testing
- Wound packing, NoPacking
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Surgical Site Infection
Subcutaneous Tissue Irrigation With Povidone Iodine in Decreasing the Rate of Surgical Site Infection Following Cesarean Section
This study aims to assess the efficacy of Povidone Iodine (Betadine®) irrigation of subcutaneous tissue prior to skin closure in reducing the incidence of surgical site infection after elective caesarean section and post…
- Trial name
- NCT03549702
- Testing
- Povidone iodine 1% solution
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Surgical Site Infection
WHO Checklist- Based Infection Prevention Guidelines in Mulago Hospital
This prospective cohort study will assess all mothers undergoing elective and emergency caesarean delivery in the labour ward theatre at Mulago National Referral Hospital based temporarily at Kawempe Hospital.
- Trial name
- NCT03822039
- Where
- Uganda
- Volunteers
- 768 people
- Sponsor
- Makerere University
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