Clinical trials: Wound Infections
Pancreatitis
The Development of Pancreatic Injury in the Course of Severe Acute Respiratory Syndrome Coronavirus 2 Infection
Although COVID-19 disease due to Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the respiratory tract, heart and coagulation system, symptoms of gastrointestinal system involvement such as abdominal pain…
- Trial name
- NCT04433754
- Testing
- biochemical analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Uşak University
Surgical Site Infections, Colorectal Cancer
Risk Factor Assessment for the Development of Surgical Site Infection in Patients Undergoing Colorectal Cancer Surgery
Surgical site infection (SSI) is a common complication following colorectal cancer (CRC) surgery and represents a significant cause of slower postoperative recovery and prolonged hospital stay.
- Trial name
- NCT07104903
- Testing
- Data collection from medical records
- Where
- Serbia
- Volunteers
- 62 people
- Sponsor
- Oncology Institute of Vojvodina
Wound Infection
Comparing Outcomes for Prontosan Versus Normal Saline for Negative Pressure Wound Therapy With Instillation
This is a prospective, randomized trial comparing the outcomes for Prontosan versus normal saline as the solution for negative pressure wound therapy with instillation (NWPTi).
- Trial name
- NCT01939145
- Testing
- Normal saline, Prontosan
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Georgetown University
Respiratory Distress Syndrome, Adult, Pneumonia
Comparison Study of High Frequency Percussive Ventilation With Conventional Ventilation
This study is designed to exam the effects of early management with high frequency percussive ventilation (HFPV) on patients with lung injury.
- Conditions
- Respiratory Distress Syndrome, Adult, Pneumonia, Mechanical Ventilation
- Trial name
- NCT00308022
- Testing
- High Frequency Percussive Ventilation
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Of Bypass Graft of the Extremities, Peripheral Arterial Disease
Standard Versus PICO Dressings in Lower-Extremity Bypass Patients
The objective of this study is to compare the effectiveness of standard moist dressings and PICO single-use negative pressure dressings in post-operative lower extremity bypass patients.
- Conditions
- Of Bypass Graft of the Extremities, Peripheral Arterial Disease, Vascular Diseases, Cardiovascular Diseases
- Trial name
- PICO-LEB (NCT02492854)
- Testing
- PICO Single-Use Negative Pressure Dressings, Sterile Gauze Dressings
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Boston Medical Center
Skin Disease, Infectious
Sivextro in Acute Bacterial Skin and Skin Structure Infection (ABSSSI) in Hospitalized Patients. A Global Observational Study
This open-label, prospective, multi-center, non-interventional, observational, parallel cohort study intended to provide real life data on the treatment duration, effectiveness and safety of tedizolid and linezolid when treating…
- Trial name
- DART (NCT02991131)
- Testing
- Tedizolid (Sivextro, BAY1192631), Linezolid
- Where
- 3 sites in Mexico, Russia and 1 more
- Volunteers
- 108 people
- Sponsor
- Bayer
Sepsis, Temperature
Temperature Optimization in Afebrile Septic PatienTs
The goal of this interventional study is to learn if external warming works to treat patients with a serious systemic infection (i.e. sepsis) that do not have fever.
- Trial name
- TOAST (NCT07831057)
- Testing
- External Warming
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Matt Harmon
Covid19, ARDS, Human
Exhaled Breath Particles as a Clinical Indicator for Lung Injury and Acute Respiratory Distress Syndrome (ARDS)
Acute Respiratory Distress Syndrome (ARDS) reflects the hallmark of the critical course of coronavirus (COVID19). The investigators have recently shown that Exhaled Breath Particles (EBP) measured as particle flow rate (PFR) from…
- Conditions
- Covid19, ARDS, Human, ALI
- Trial name
- NCT04503057
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Lund University Hospital
Liver Transplant Infection, Surgical Site Infection
Pharmacological Study of Cefazolin Antibioprophylaxis in Liver Transplantation
This study describes Cefazolin pharmacokinetics variation to target levels during liver transplantation.
- Conditions
- Liver Transplant Infection, Surgical Site Infection, Antibiotic Prophylaxis, Cephazolin Adverse Reaction
- Trial name
- ProCeTH (NCT04280237)
- Testing
- Blood samples
- Where
- France
- Sponsor
- University Hospital, Tours
Wound Infection, Breast Neoplasms
Wound Infections in Breast Cancer Surgery After Preoperative Skin Preparation With Chlorhexidine vs. Povidone-iodine
The development of surgical site infections (SSI) in clean-contaminated surgery is regarded as being preventable. Known to be effective in the prevention of surgical site infection are the adequate sterilization of the surgical…
- Trial name
- NCT02479347
- Testing
- Chlorhexidine, Povidone-Iodine
- Where
- Italy
- Volunteers
- 2,158 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Infant, Newborn, Hypertension, Pulmonary
Inhaled Nitric Oxide Study for Respiratory Failure in Newborns
Respiratory failure in term newborns is associated with increased rates of death and long-term neurodevelopmental problems. This large international multicenter trial randomized newborns who had failed to respond to intensive…
- Conditions
- Infant, Newborn, Hypertension, Pulmonary, Persistent Fetal Circulation Syndrome, Pneumonia, Aspiration
- Trial name
- NINOS (NCT00005776)
- Testing
- Inhaled nitric oxide
- Where
- 20 sites in United States, Canada
- Volunteers
- 235 people
- Sponsor
- NICHD Neonatal Research Network
Abscess
Antibiotic Therapy After Incision and Drainage for Abscess
Background: Skin abscesses are a growing problem in the general pediatric population around the world. While the standard treatment for an abscess/boil is incision and drainage, many physicians also prescribe antibiotics, despite…
- Trial name
- NCT00900510
- Testing
- Incision and drainage, Trimethoprim/Sulfamethoxazole (Bactrim)
- Where
- United States
- Sponsor
- Wake Forest University
Surgical Wound Infection, Peripheral Vascular Diseases
Negative Pressure Wound Therapy for the Prevention of Surgical Site Infection Following Lower Limb Revascularization
The purpose of this study is to investigate the current standard of wound care following vascular operations compared to to a negative pressure wound therapy (vacuum dressing) and the rate of surgical site infections (SSIs) in…
- Trial name
- NCT02084017
- Testing
- Prevena (Negative Pressure Wound Therapy Device), Standard Tegaderm (3M Healthcare, St. Paul, MN) adhesive dressing
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Western University, Canada
Wound Infection, Complication, Postoperative
Chlorhexidine Gluconate vs Povidone-Iodine Vaginal Cleansing Solution Prior to Cesarean Delivery
Endometritis, an infection of the uterus in the postpartum period, has been shown to complicate the postoperative course of a cesarean delivery in 6% to 27% of cases.
- Trial name
- NCT02915289
- Testing
- Povidone Iodine, Chlorhexidine gluconate
- Where
- United States
- Volunteers
- 1,114 people, healthy volunteers welcome
- Sponsor
- Richmond University Medical Center
Corona Virus Disease 19 (COVID-19), COVID
Rehabilitation for People With COVID-19 in ICU
COVID-19 DISEASE Coronavirus disease 2019 (COVID-19) is a respiratory tract infection caused by a newly emergent coronavirus, severe acute respiratory syndrome from COVID-19, that was first recognized in Wuhan, China, in December…
- Conditions
- Corona Virus Disease 19 (COVID-19), COVID, Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS), Critical Illness
- Trial name
- COVID_REHAB (NCT04381338)
- Testing
- Pulmonary and Motor Rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 96 people
- Sponsor
- University of Padova
Infected Wound, Diabetic Wound
Vacuum-assisted Closure Versus Conventional Dressings in Infected Lower-limb Wounds
Wound healing is a complex and dynamic process that includes an immediate sequence of cell migration leading to repair and closure.
- Trial name
- NCT07795489
- Testing
- Vacuum-Assisted Closure (VAC) Therapy, Conventional dressing
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Sargodha Medical College
COVID-19, Lung Injury
Clinical Trial to Evaluate Methylprednisolone Pulses and Tacrolimus in Patients With COVID-19 Lung Injury
The primary objective of the study is to evaluate the days until reaching clinical stability after starting randomization in hospitalized patients with elevated inflammatory parameters and severe COVID-19 lung injury.
- Trial name
- TACROVID (NCT04341038)
- Testing
- Tacrolimus, Methylprednisolone
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Hospital Universitari de Bellvitge
Healthy Volunteers, Fungal Infections
A Pilot of Pediatric/Adult Study of Gene Expression Profiling and Clinical Characterization of Phototoxicity
This study will examine the phototoxicity, a reaction to light that is like exaggerated sunburn, which occurs in people who take medications such as voriconazole, a medication used to fight fungus.
- Conditions
- Healthy Volunteers, Fungal Infections, Bacterial Infections
- Trial name
- NCT00353158
- Testing
- Doxycycline, Voriconazole
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Heart Failure, Community Acquired Pneumonia
Collaborative Healthcare Professionals Approach in Monitoring of Patient Centered Outcomes Through Pathways
The aim of this study is to determine if by providing a collaborative, integrated pathway-based healthcare compared to the usual healthcare, whether or not this would be superior in reducing the length of hospital stay across…
- Conditions
- Heart Failure, Community Acquired Pneumonia, Venous Thromboembolism, Acute Kidney Injury
- Trial name
- CHAMP-Path (NCT01561885)
- Testing
- Pathway-Based Care
- Where
- Saudi Arabia
- Volunteers
- 341 people
- Sponsor
- Majed Aljeraisy
Cesarean Section, Surgical Wound
To Explore the Effectiveness and Feasibility of HERADERM Hydrogel Wound Dressing on Caesarean Section Surgical Site
The wound of cesarean section involves multiple layers of tissue and often cause significant postoperative pain. The epidermal wound typically heals within 1 to 2 weeks after surgery.
- Conditions
- Cesarean Section, Surgical Wound, Surgical Wound Infection, Wounds and Injuries
- Trial name
- NCT06558240
- Testing
- HERADERM Hydrogel Wound Dressing (Sterile)
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.