Clinical trials: Wound Surgical
Lung Injury, Acute and Respiratory Distress Syndrome, Adult
Study of GSK2862277 in Subjects Undergoing Oesophagectomy Surgery
Lung injury in patients undergoing oesophagectomy may occur during surgery (peri-operatively) as a result of One Lung Ventilation (OLV) and/or during the immediate post-operative period when patients receive intensive care.
- Trial name
- NCT02221037
- Testing
- GSK2862277
- Where
- 6 sites in United Kingdom
- Volunteers
- 35 people
- Sponsor
- GlaxoSmithKline
Post-operative Complications, Surgical Site Infection
The Use of the Prevena™ Incision Management System on Post-Surgical Cesarean Section Incisions
The purpose of this study is to compare the post-surgical standard-of-care dressing to the Prevena™ Incision Management System in women undergoing Cesarean section surgery.
- Conditions
- Post-operative Complications, Surgical Site Infection, Surgical Wound Infection
- Trial name
- NCT01450631
- Testing
- Prevena™ Incision Management System (PIMS), Standard-of-care Dressing
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- KCI USA, Inc
Bladder Injury, Complications; Cesarean Section
Cystoinflation to Prevent Bladder Injury in Obstetrics and Gynaecology Surgery
Part1:The healthy pregnant women with previous operative deliveries admitted for elective C-section will be counselled and conditioned informed consent will be taken to be included in either study group if dense pelvic adhesions…
- Conditions
- Bladder Injury, Complications; Cesarean Section, Adhesions Pelvic
- Trial name
- NCT04302545
- Testing
- Cystoinflation
- Where
- Pakistan
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- Shazia Saaqib
Surgical Site Infection
Chlorhexidine-Alcohol Versus Povidone-Iodine for Cesarean Antisepsis
Primary Hypothesis: chlorhexidine gluconate alcohol skin antiseptic preparation is superior to povidone-iodine scrub and paint skin antiseptic preparation for prevention of cesarean related surgical site infection.
- Trial name
- CAPICA (NCT02202577)
- Testing
- Chlorhexidine - Isopropyl alcohol, Povidone-Iodine Scrub and Paint
- Where
- United States
- Volunteers
- 932 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Non-melanoma Skin Cancer
Healing Effects of HP802-247 Versus Antibiotic Ointment in Mohs Micrographic Surgery Patients
This study compares HP802-247 versus an antibiotic ointment for healing the wound after Mohs surgery.
- Trial name
- NCT01359735
- Testing
- HP802-247, Bacitracin Ointment
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Healthpoint
ACL, ACL Injury
Acupuncture ACL (Anterior Cruciate Ligament)
Acupuncture research in regards to PONV has been fairly well established, however, studies about perioperative pain control and acupuncture are a little more murky.
- Conditions
- ACL, ACL Injury, Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
- Trial name
- NCT03711734
- Testing
- Acupuncture + Standard of Care
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Hypertrophic
Investigation of a Novel Silicone Dressing to Maximize the Outcomes of Scar Revision Procedures (IMPROVE)
Neodyne has developed an investigational dressing for post-operative incision care. Neodyne is conducting this research to study whether the investigational dressing, called the Neodyne Dressing, can minimize scar formation in a…
- Trial name
- IMPROVE (NCT01430130)
- Testing
- embrace device
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Neodyne Biosciences, Inc.
Hip Fracture, Myocardial Ischemia
Pilot Study of Atorvastatin for Orthopedic Surgery Patients
Up to 35% of hip fracture patients have been shown to experience heart injury after surgery, and as many as 10% have a heart attack or die in the three months after surgery.
- Conditions
- Hip Fracture, Myocardial Ischemia, Inflammation
- Trial name
- POST-OP Pilot (NCT02197065)
- Testing
- Atorvastatin
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Hospital for Special Surgery, New York
Late Effects of Surgery, Staphylococcus Aureus
Pharmacokinetics of Daptomycin During Cardiopulmonary Bypass Surgery
This investigation is a prospective, open-label pharmacokinetic study of daptomycin prophylaxis in patients undergoing coronary artery bypass graft surgery without valvular replacement.
- Conditions
- Late Effects of Surgery, Staphylococcus Aureus, Surgical Site Infection
- Trial name
- NCT00701636
- Testing
- daptomycin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Rupture, Venous Thromboembolism
Compression Treatment Effects on Complications and Healing of Achilles Tendon Rupture
This prospective randomized study aims to determine whether intermittent pneumatic compression (IPC), 75 patients, beneath functional bracing compared to treatment-as-usual in plaster cast, 75 patients, can reduce the Venous…
- Conditions
- Rupture, Venous Thromboembolism, Venous Thrombosis, Surgical Wound Infection
- Trial name
- NCT01317160
- Testing
- Intermittent pneumatic compression (IPC)
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Karolinska University Hospital
Quadratus Lumborum Block, Surgical Wound Infiltration
Surgeon Infiltration QL Block Comparison
The purpose of this study is to learn if using a Quadratus Lumborum (QL) plane injection technique (also called a "nerve block") that numbs the nerves going to the abdominal area improve pain control after surgery compared to…
- Trial name
- NCT03496610
- Testing
- Liposomal Bupivicaine, QL Block
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Duke University
Surgical Incisions
Prineo (Dermabond Protape) Versus Sutures for Full-thickness Surgical Incisions
This is a prospective, controlled, randomized, multi-center clinical study of up to 80 subjects with full thickness surgical incisions.
- Trial name
- NCT00557947
- Testing
- Suture, Dermabond Protape (Prineo)
- Where
- 5 sites in Belgium, Germany and 2 more
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Ethicon, Inc.
Esophageal Subepithelial Lesions
EUS-CNB Versus EUS-SINK for Diagnosis of Upper Gastrointestinal (UGI) Subepithelial Tumors
This is a single-blinded randomized control trial trying to compare the effectiveness of diagnosis between two techniques employed in tissue sampling for subepithelial tumors (SETs) of the gastrointestinal tract.
- Trial name
- NCT02282111
- Testing
- 22-gauge Procore needle (ProCore, Cook Medical Inc., Winston-Salem, NC), conventional needle-knife sphincterotome (Microknife XL; Boston Scientific Inc, Natick, Mass)
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Johns Hopkins University
Fatigue
Bundling and Unbundling the Laparoscopic Electrosurgery Cord With the Camera Cord
Electrosurgery is used in virtually every laparoscopic operation performed. Capacitive coupling is a common electrosurgery complication.
- Trial name
- NCT01707095
- Testing
- Unbundling of cords, Bundling of cords
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Scar Prevention
Safety and Efficacy Study of Different Dose Levels of EXC 001 to Improve the Appearance of Scars in Subjects Undergoing Elective Abdominoplasty
This study will compare how well EXC 001 works versus placebo in reducing the appearance of scars in subjects undergoing elective abdominoplasty. The study will also evaluate the safety of EXC 001 in healthy adult subjects.
- Trial name
- NCT01038297
- Testing
- EXC 001
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Pfizer
Colorectal Surgery
Efficacy Comparison of Two Preoperative Skin Antisepsis Preparations in Colorectal Surgery
Surgical site infections (SSI) are one of the most common complications in the post-operative patient, and the second most common health care associated infection overall.
- Trial name
- NCT01233050
- Testing
- 2% Chlorhexidine Gluconate/70% Isopropyl Alcohol, Iodine Povacrylex/74% Isopropyl Alcohol
- Where
- 3 sites in United States
- Volunteers
- 802 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Supracondylar Humerus Fracture, Post Operative Wound Infection
Antibiotics Usage in Pediatric Orthopaedic Percutaneous Surgery (APOPS)
The aim of this study is to determine if antibiotics affect the outcome after percutaneous surgery for pediatric supracondylar humerus fractures.
- Trial name
- NCT03261830
- Testing
- Cefazolin, Clindamycin, Saline
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Sumit Gupta
Cesarean Section
Comparison Study of Wound Closure at Time of Cesarean Delivery: Dermabond Glue Versus Surgical Staples
Women who have a cesarean delivery have a surgical incision on their abdomen (belly). The usual way to close this opening is with metal surgical staples.
- Trial name
- NCT00524511
- Testing
- Surgical skin staples, Dermabond
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- University of Massachusetts, Worcester
Abscess
Management of Skin and Soft Tissue Abscesses in Pediatric Patients After Incision and Drainage
The purpose of the study is to compare rates of cure of abscesses with and without antibiotic treatment after incision and drainage.
- Trial name
- NCT00691600
- Testing
- oral trimethoprim/sulfamethoxazole
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Baylor College of Medicine
Osteoarthritis
Antimicrobial Barrier Dressing Versus Closed-incision Negative Pressure Therapy in the Obese Primary Total Joint Arthroplasty
The purpose of this study is to determine whether an occlusive antimicrobial barrier dressing or portable negative pressure wound dressing is superior in preventing wound complications and infection rates in obese patients…
- Trial name
- NCT03345771
- Testing
- Antimicrobial Barrier Dressing, Negative Pressure Wound Therapy (NPWT)
- Where
- United States
- Volunteers
- 230 people
- Sponsor
- NYU Langone Health