Clinical trials: Wound and Injuries
Spinal Cord Injury, Spinal Cord Injury Cervical
Spine and Brain Stimulation for Movement Recovery After Cervical Spinal Cord Injury
Stimulation of the spinal cord and brain represents a new experimental therapy that may have potential to restore movement after spinal cord injury.
- Trial name
- NCT06867809
- Testing
- Epidural spinal cord stimulation and paired spine and brain stimulation
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Jason Carmel
PTSD
Can Exercise Improve Therapeutic Learning Among Women With Posttraumatic Stress Disorder
This study aims to test whether aerobic exercise improves the consolidation and subsequent recall of the learned safety memories among adult women with PTSD related to interpersonal violence exposure and whether this effect is…
- Trial name
- PTSD (NCT04417309)
- Testing
- Experimental, Active Control
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Thomas Adams
Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)
VExUS in Ards Patients and Association with AKI
A single-center prospective observational study will be conducted with the aim of determining the prevalence of venous congestion during ARDS using venous Doppler and the VExUS score.
- Trial name
- VEXAKI (NCT06805409)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Posttraumatic Stress Disorder, Major Depressive Disorder
Risk and Resiliency Factors in the RCMP: A Prospective Investigation
The Royal Canadian Mounted Police (RCMP), like all public safety personnel (PSP), are frequently exposed to potentially psychologically traumatic events that contribute to posttraumatic stress injuries (PTSI).
- Conditions
- Posttraumatic Stress Disorder, Major Depressive Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT05527509
- Testing
- Emotional Resilience Skills Training (ERST), Active Monitoring
- Where
- Canada
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- University of Regina
Elbow Pain, Supracondylar Humerus Fracture
The Utilization of Ultrasound to Diagnose Pediatric Elbow Fractures
The goal of this intervention trial is to learn if a ultrasound diagnosis of elbow fractures can improve care in pediatric patients seen in the emergency room.
- Conditions
- Elbow Pain, Supracondylar Humerus Fracture, Radial Head Fractures, Radial Head or Neck Fractures
- Trial name
- NCT07212036
- Testing
- Ultrasound of the elbow, X-ray of elbow
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Major Injury
Perioperative Research Into Memory: Cognitive Outcome Following Major Burns
The long term survival of patients who require admission to critical care (CC) following a major burn injury (MBI) continues to improve with advanced clinical management.
- Trial name
- PRiMe (NCT03470844)
- Testing
- Face-to-face neurocognitive tests, Psychological screening, fMRI
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Hip Fractures
Impact of "ASAP" Multidisciplinary Optimization Care Protocol on Clinical Outcome in Elderly Inpatients for Hip Fracture
To compare the impact of ASAP protocol (geriatric advice, early surgery, loco-regional anesthesia and pharmacological adaptation) on elderly patients with hip fracture and clinical outcome.
- Trial name
- NCT04771364
- Testing
- ASAP care's protocol
- Where
- Belgium
- Volunteers
- 800 people
- Sponsor
- University of Liege
Knee Injuries, Knee Osteoarthritis
Walking Gait Biomechanics Following Knee Joint Effusion
The purpose of this study is to determine the sensitivity of a wearable sensor to detect changes in knee joint loading using an experimental knee joint effusion as a model for a common clinical physiological alteration in joint…
- Trial name
- NCT03805464
- Testing
- Knee Joint Effusion
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Duke University
Concussion
Evaluation of an EEG Based Concussion System
This study will evaluate the accuracy of a new concussion system at detecting concussions. The investigators will be evaluating the degree to which data collected with the device agrees with a physician's determination of a…
- Trial name
- NCT03710109
- Testing
- EEG
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Acquired Brain Injury, Stroke
Computerized Attention Training for Individuals With Acquired Brain Injury
Problems with attention are a common and debilitating consequence of brain injury. Studies show that poor attention is the number one predictor of poor cognitive functioning one year post-injury.
- Conditions
- Acquired Brain Injury, Stroke, Hemispatial Neglect
- Trial name
- NCT01641432
- Testing
- Tonic and Phasic Attention Training, Active Comparator
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Posit Science Corporation
Osteopenic Women
Bone Quality Lyon Orleans
QUALYOR is a prospective study on the predictive value for fragility fracture of various new techniques assessing bone quality, among postmenopausal women with low bone mass.
- Trial name
- QUALYOR (NCT01150032)
- Testing
- Bone quality complementary exams
- Where
- 2 sites in France
- Volunteers
- 1,605 people
- Sponsor
- Hospices Civils de Lyon
Dizziness, Equilibrium; Disorder, Labyrinth
Posturography-assisted Vestibular Retraining for Stable Unilateral Vestibular Deficit
People that have difficulty with balance have a higher risk of falling and reduced quality of life. Some individuals can learn to compensate using their vision, their sense of where their limbs are in space, and balance organs…
- Conditions
- Dizziness, Equilibrium; Disorder, Labyrinth, Inner Ear Injury, Inner Ear Disease
- Trial name
- NCT05115032
- Testing
- Vestibular retraining with dynamic posturography, At-home rehabilitation exercises
- Where
- Canada
- Volunteers
- 37 people
- Sponsor
- Eytan A. David
HIV/AIDS, Trauma
Trauma Informed Intervention to Support Engagement in HIV Care Among MSM (THRIVE+)
This purpose of this project is to specify and provide an initial test of a 10 session, individual-based cognitive therapy intervention to address symptoms of PTSD and poor engagement in HIV care among men who have sex with men…
- Trial name
- THRIVE+ (NCT05822206)
- Testing
- CBT-TSC, Life Steps and Sexual Decision-Making
- Where
- 2 sites in United States, Canada
- Volunteers
- 40 people
- Sponsor
- Massachusetts General Hospital
Anterior Cruciate Ligament Injuries, Knee Injuries
Graft Type and Outcomes After ACL Reconstruction in Female Athletes
This prospective multicenter cohort study aims to compare clinical and functional outcomes between hamstring tendon and quadriceps tendon autografts in anterior cruciate ligament (ACL) reconstruction in female athletes.
- Trial name
- LCA-WOMEN (NCT07722104)
- Testing
- Hamstring tendon autograft ACL reconstruction, Quadriceps tendon autograft ACL reconstruction
- Where
- Spain
- Volunteers
- 82 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Trauma
Evaluating the New Trauma Score (NTS) for Improved Mortality Prediction
The goal of this prospective cohort study is to evaluate the predictive accuracy of the New Trauma Score (NTS), a modification of the Revised Trauma Score (RTS), in determining mortality outcomes among trauma patients admitted to…
- Trial name
- NTS (NCT06732752)
- Where
- Iraq
- Volunteers
- 177 people
- Sponsor
- Al-Nahrain University
PTSD, Trauma, Psychological
Narrative Exposure Therapy for Adults With Intellectual Disability
The purpose of the study is to identify how Narrative Exposure Therapy (NET) can be adapted for delivery with adults with mild Intellectual Disability (ID) and to explore whether NET can reduce symptoms of traumatic stress in…
- Trial name
- NCT04418752
- Testing
- Psychological therapy
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nottingham
Pathogenesis, Acute Kidney Injury
Perioperative Mechanism of Acute Kidney Injury in Cardiovascular Surgery
Continuous observation of acute renal injury after cardiac surgery, at the same time retention of blood samples, to test indicators，and to select the research route from the clinical actual test results .
- Conditions
- Pathogenesis, Acute Kidney Injury, Cardiac Surgery
- Trial name
- NCT03557047
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The First Affiliated Hospital of Anhui Medical University
COVID-19, Endothelial Dysfunction
The Glycocalyx in COVID-19 Patients. A Pilot Study
The damage of the endothelial glycocalyx is based on microvascular endothelial dysfunction and typical for critical clinical conditions like sepsis, trauma, bleeding, shock, as well as ARDS.
- Conditions
- COVID-19, Endothelial Dysfunction, Coagulation Disorder
- Trial name
- Glycovid-19 (NCT05137249)
- Where
- Austria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Venous Leg Ulcer (VLU)
ConvaVAC™ Ag+ Negative Pressure Wound Therapy System in Chronic Wounds
Purpose of this study is to learn more about how safe and effective the ConvaVAC™ Ag+ wound therapy system is in treating certain types of long-lasting wounds, called chronic wounds.
- Trial name
- ConvaVAC VLU (NCT07342049)
- Testing
- ConvaVAC™ Ag+ Negative Pressure Wound Therapy System
- Where
- 7 sites in Chile, United Kingdom
- Volunteers
- 87 people
- Sponsor
- ConvaTec Inc.
Shoulder Pain, Shoulder Impingement Syndrome
Micro-Fragmented Adipose Tissue (Lipogems®) Injection for Chronic Shoulder Pain in Persons With Spinal Cord Injury
Rotator cuff disease (i.e., rotator cuff tendinopathy or tear) is a common cause of shoulder pain in persons with chronic spinal cord injury (SCI).
- Conditions
- Shoulder Pain, Shoulder Impingement Syndrome, Rotator Cuff Impingement Syndrome, Rotator Cuff Tendinitis
- Trial name
- NCT03167138
- Testing
- Autologous micro-fragmented adipose tissue, Lipogems system
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kessler Foundation