Clinical trials: Wounds
Obstruction, Cancer
Intravenous Nutrition in Hospitalized Patients: Comparison of Two Oils
Intravenous nutrition is an important therapy for the recovery of many patients. It is indicated when the patients cannot take food by mouth or use their intestines for feeding.
- Conditions
- Obstruction, Cancer, Ileus, Malnutrition
- Trial name
- NCT01943409
- Testing
- Intralipid, ClinOleic
- Where
- Canada
- Volunteers
- 303 people
- Sponsor
- Johane Allard
Rib Fractures, Trauma
Continuous Erector Spinae Plane Blocks for Rib Fractures
Rib fractures are one of the most common injuries in trauma patients. These fractures are associated with significant pain as well as decreased ability to inspire deeply or cough to clear secretions, which together lead to…
- Conditions
- Rib Fractures, Trauma, Anesthesia, Anesthesia, Local
- Trial name
- NCT04558281
- Testing
- Active ropivacaine 0.3% erector spinae plane perineural administration
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Diego
Traumatic Brain Injury
Intervention to Promote Survivor Resilience and Adjustment: Efficacy and Sustainability
The aims of this traumatic brain injury (TBI) study are: 1. to evaluate the short and long-term efficacy of two structured outpatient intervention programs, Resilience and Adjustment Intervention (RAI) vs.
- Trial name
- NCT03421964
- Testing
- Resilience/Adjustment Counseling, Resilience/Adjustment Counseling with Booster Sessions
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- Virginia Commonwealth University
Vertebral Artery Dissection, Cerebrovascular Accident
Vertebral Artery and Cerebral Hemodynamics After Various Head Positions & Manipulation in Patients With Neck Pain
The Investigators are performing a study to determine, in patients with chronic/recurrent neck pain, the cerebrovascular hemodynamic consequences of cervical spine movements, including manipulation, in vivo using fMRI technology…
- Conditions
- Vertebral Artery Dissection, Cerebrovascular Accident, Stroke
- Trial name
- NCT02667821
- Testing
- Head positions and spinal manipulation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Canadian Memorial Chiropractic College
Opioid Use, Shoulder Osteoarthritis
Opioid-Free Shoulder Arthroplasty
Purpose of Study: To identify and provide a safe, opioid-free treatment pathway for shoulder arthroplasty with a focus on perioperative pain control and postoperative symptoms from treatment
- Conditions
- Opioid Use, Shoulder Osteoarthritis, Avascular Necrosis, Rotator Cuff Tear
- Trial name
- NCT03540030
- Testing
- Gabapentin, Celecoxib, toradol
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Injury Leg
Sensors Prediction Study
The purpose of this study is to test whether measures of balance and agility can help predict if a Service Member may be at risk for an injury to their legs before beginning their school and training.
- Trial name
- NCT04541992
- Where
- United States
- Volunteers
- 1,891 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cardiac Toxicity, Chemotherapeutic Agent Toxicity
Cardiac Magnetic Resonance Imaging in Patients With Non-Hodgkin Lymphoma or Hodgkin Lymphoma Receiving Doxorubicin
RATIONALE: Diagnostic procedures, such as cardiac magnetic resonance imaging, may help doctors detect early changes in the heart caused by chemotherapy.
- Conditions
- Cardiac Toxicity, Chemotherapeutic Agent Toxicity, Lymphoma
- Trial name
- NCT00577798
- Testing
- contrast-enhanced magnetic resonance imaging
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Injury of Anterior Cruciate Ligament
Opioid Use in Single Shot Nerve Block vs Continuous Peripheral Nerve Infusion in Anterior Cruciate Ligament (ACL) Repair
Anterior cruciate ligament repair using hamstring autograft in children is a painful orthopedic procedure. The current practice to provide analgesia for this procedure include femoral continuous perineural infusion and femoral…
- Trial name
- NCT02075411
- Testing
- bupivacaine, continuous perineural infusion catheter
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Children's Hospital of Philadelphia
Atrial Fibrillation, AFib
Stroke Feasibility Study
This is a feasibility study to assess the safety and efficacy of the AtriCure AtriClip when placed via Minimally Invasive Surgical Deployment to the Left Atrial Appendage.
- Trial name
- NCT01997905
- Testing
- AtriClip LAA Exclusion Device
- Where
- 7 sites in United States
- Volunteers
- 13 people
- Sponsor
- AtriCure, Inc.
Spinal Cord Injury
Resistance Training and Testosterone After Spinal Cord Injury
The goal of this proposal is to investigate the efficacy of a complimentary approach of evoked resistance training and testosterone replacement therapy on the changes in body composition and metabolic profile after SCI.
- Trial name
- NCT01652040
- Testing
- Resistance Training and Testosterone Patches, Testosterone Patches
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- VA Office of Research and Development
Upper Extremity Injury, Sport Injury
Throwers Ten Exercises On Upper Extremity Function and Explosive Power in Wheelchair Basketball and Basketball Players
Basketball is a challenging sport that requires participants to demonstrate physical fitness and special athletic skills at high levels.
- Conditions
- Upper Extremity Injury, Sport Injury, Shoulder Pain, Muscle Weakness
- Trial name
- NCT04019990
- Testing
- The effect of throwers ten exercise programme on wheelchair basketball and ambulant basketball players
- Where
- Cyprus
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Persian Gulf Syndrome
Treatment Study of Carnosine Versus Placebo in Gulf War Illness (GWI)
The purpose of this study is to perform a randomized double-blind, placebo-controlled, 12 week study of the effects of carnosine on cognitive, psychometric, autonomic, and muscle strength outcomes in 100 GWI subjects.
- Trial name
- NCT00810368
- Testing
- Carnosine
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Georgetown University
Osteoporosis, Postmenopausal, Osteoporosis
Preventing Osteoporosis Using Denosumab
The purpose of this research study is to find out if denosumab (Prolia®), an injection given in the arm under the skin every 6 months, works to treat bone loss and prevent it from worsening in older men and women (ages 65 and…
- Conditions
- Osteoporosis, Postmenopausal, Osteoporosis, Osteoporotic Fractures
- Trial name
- PROUD (NCT02753283)
- Testing
- denosumab, Calcium and Vitamin D
- Where
- United States
- Volunteers
- 201 people
- Sponsor
- Susan L. Greenspan
Post-traumatic Stress Disorder, Traumatic Brain Injury
Multisite RCT of STEP-Home: A Transdiagnostic Skill-based Community Reintegration Workshop
In this proposal, the investigators extend their previous SPiRE feasibility and preliminary effectiveness study to examine STEP-Home efficacy in a RCT design.
- Conditions
- Post-traumatic Stress Disorder, Traumatic Brain Injury, Substance Related Disorders, Depression
- Trial name
- STEP-Home (NCT03868930)
- Testing
- STEP-Home, PCGT
- Where
- 2 sites in United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Stroke, Brain Injury
Use of the Passy Muir Swallowing Self Trainer
The purpose of this study is to develop appropriate training methods and gather participant feedback on their use of the Passy Muir Swallowing Self-Training Device (PMSST).
- Conditions
- Stroke, Brain Injury, Head and Neck Cancer
- Trial name
- NCT02848664
- Testing
- Dysphagia retraining with device
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- James Madison University
Injuries, Shock, Traumatic
Low Dose Vasopressin in Traumatic Shock
Hypothesis: We hypothesize that resuscitation regimens which minimize the total volume of resuscitation fluid, while restoring organ perfusion, will lead to lower morbidity and mortality in critically ill patients following…
- Trial name
- NCT00420407
- Testing
- normal saline control, vasopressin
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Foot Injury, Foot Deformity
Comparing Clinical Outcomes Using Two Insole Manufacture Techniques
The main purpose of this study is to find out if scanning the foot using a 3D scanner influences the effectiveness of custom made insoles, compared to the more traditional approach of taking a foam-box impression cast of the…
- Conditions
- Foot Injury, Foot Deformity, Foot Sprain, Feet, Flat
- Trial name
- NCT05444192
- Testing
- CAD/CAM insoles
- Where
- United Kingdom
- Volunteers
- 114 people
- Sponsor
- NHS Greater Glasgow and Clyde
Chronic Pain
Study to Evaluate the Long-Term Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) in Patients Who Require Opioid Treatment for an Extended Period of Time
The primary objective of this study is to evaluate the safety of hydrocodone extended-release tablets when used over a 12-month period in patients with chronic pain, as assessed by adverse events, clinical laboratory results…
- Trial name
- NCT01223365
- Testing
- Hydrocodone ER
- Where
- 54 sites in United States
- Volunteers
- 330 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Osteoporotic Fractures
PTH(1-34) and Pelvic Fracture Healing - a Randomized Controlled Trial
In the proposed trial the investigators will recruit women and men >65 years of age with acute osteoporosis-related pelvic fractures and address 3 specific aims over 3 months of treatment in a placebo controlled double blind…
- Trial name
- NCT02972424
- Testing
- Teriparatide Prefilled Syringe
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Hospital for Special Surgery, New York
Osteopenia, Osteoporosis
Extension Study to Evaluate the Long Term Safety and Efficacy of Denosumab in the Treatment of Osteoporosis
The primary objective was to describe the safety and tolerability of up to 10 years or 7 years denosumab administration as measured by adverse event monitoring, immunogenicity and safety laboratory parameters in participants who…
- Trial name
- NCT00523341
- Testing
- Denosumab
- Volunteers
- 4,550 people
- Sponsor
- Amgen
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