Clinical trials: Wounds and Injuries, Ankles
Lower Limb Injury, Ankle Foot Orthosis (AFO)
IM ABLE 2: Injuries Managed With Advanced Bracing for Lower Extremities
The purpose of the study is to test different categories of ankle foot orthoses (AFOs) with patients who have had lower limb salvage, reconstruction or other problems impacting limb function.
- Conditions
- Lower Limb Injury, Ankle Foot Orthosis (AFO), Lower Limb Trauma
- Trial name
- IM ABLE 2 (NCT07721792)
- Testing
- Advanced Ankle Foot Orthosis (AFO), Conventional Ankle Foot Orthosis (AFO)
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- University of South Florida
Ankle Sprain
Diclofenac Patch for Treatment of Mild to Moderate Ankle Sprain
The primary purpose of this study is to assess the effectiveness of once daily application of a diclofenac sodium patch to the skin near or over the painful area.
- Trial name
- NCT00640705
- Testing
- diclofenac sodium
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Cerimon Pharmaceuticals
Primary Disease or Condition Being Studied in the Trial or the Focus of the Study Mild Ankle Sprain
Mild Ankle Sprain Treatment: Functional Bandaging vs. no Immobilization
Ankle sprains represent a prevalent pathology among the pediatric population that can result in residual effects when treated incorrectly.
- Trial name
- PED_HUIL0124 (NCT06222229)
- Testing
- Control, Functional bandage
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Hospital Universitario Infanta Leonor
Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease
Post-Market Registry of AURYON Atherectomy Device in Subjects Affected With Infrainguinal Peripheral Artery Disease
The PATHFINDER Registry is a prospective, non-randomized, single arm, multicenter observational study. This pilot registry is aimed to evaluate the performance (peri-procedural) and clinical outcomes (intermediate and long-term)…
- Conditions
- Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease, PAD
- Trial name
- PATHFINDER (NCT04229563)
- Testing
- AURYON Atherectomy System
- Where
- 10 sites in United States
- Volunteers
- 102 people
- Sponsor
- Angiodynamics, Inc.
Arthralgia, Trouble Balancing
Even-Up to Minimize Secondary Site Pain For Ankle Fracture
Evaluating impact of use of Even-Up shoe wear device for patients treated in CAM boot walker for an ankle fracture. Randomized controlled trial, randomizing patients into control group with boot treatment only versus boot…
- Trial name
- NCT04164563
- Testing
- Even-Up
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Ankle Injuries
Application of 3D Printing Technology in Subtalar Arthrodesis
This study aims to use 3D printing personalized plate to locate the position in which the K-wires would be drilled to save operation time and decrease the number of times that the K-wires are drilled.
- Trial name
- NCT03152916
- Testing
- 3d printing personalized plate
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Southwest Hospital, China
Unilateral Traumatic Amputation, Amputation, Traumatic
Determining the Potential Benefit of Powered Prostheses
The goal of this research is to determine the effectiveness of a powered prosthesis compared to an unpowered prosthesis during short bouts of walking, extended periods of walking (to fatigue), and performance in the community.
- Trial name
- NCT02828982
- Testing
- Powered ankle prosthesis, Dynamic Response Foot
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Deanna H Gates
Ankle Sprain
Neurocryostimulation for Acute Lateral Ankle Sprain
The objective of this exploratory randomized control trial is to compare, in participants with acute lateral ankle sprain (LAS) , the reduction of symptoms and functional limitations between two groups of subjects who undergo a…
- Trial name
- NCT02945618
- Testing
- Neurocryostimulation, Ice
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Laval University
Ankle Injuries, Ligament Injury
Medial and Lateral Combined Ligament Arthroscopic Repair for Multidirectional Ankle Instability: Case Series
Abstract Introduction: The high prevalence of sprains in the population has provided a substantial number of patients with lateral instability of the ankle.
- Conditions
- Ankle Injuries, Ligament Injury, Joint Instability, Deltoid Ligament; Sprain (Strain) (Ankle)
- Trial name
- NCT04459910
- Testing
- Arthroscopic Brostrom combined with Arthroscopic Deltoid Repair
- Where
- Brazil
- Volunteers
- 29 people
- Sponsor
- Federal University of São Paulo
Foot Injury, Ankle Injury
Ideal Anatomic Location for Saphenous Nerve Blocks: A Prospective Clinical Evaluation
This research is being done to compare two different saphenous nerve block locations and will help to determine which site best maintains knee strength and pain control.
- Trial name
- NCT02645097
- Testing
- Saphenous Nerve Block
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Paul J. Juliano, M.D.
Ankle Fractures
Preliminary Review of Cold and Active Compression Therapy for Traumatic Calcaneus or Ankle Fractures
This study will examine the initial efficacy and cost-effectiveness of using the cryocompression therapy model both pre-operatively and post-operatively in patients that have recently suffered a traumatic calcaneus or ankle…
- Trial name
- NCT02498717
- Testing
- GameReady, RICE
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- AdventHealth
Elbow Tendinopathy, Ankle Sprains
Hyaluronic Acid for Soft Tissue Injuries
Soft Tissue Adapted Biocompatible Hyaluronic Acid, or STABHA™, has demonstrated varying degrees efficacy in patients treated for common musculoskeletal tendinopathies and ligament injuries, such as ankle sprains, lateral elbow…
- Trial name
- SAFE (NCT05278897)
- Testing
- Soft Tissue Adapted Biocompatible Hyaluronic Acid
- Volunteers
- 200 people
- Sponsor
- Global Research Solutions
Arthritis, Femoroacetabular Impingement
Conjoint Analysis of Patient Preferences in Joint Interventions
This study is an observational study to test and validate a questionnaire and statistical model used to determine patient preferences regarding treatment for any one of 11 musculoskeletal conditions: hip arthritis, knee…
- Conditions
- Arthritis, Femoroacetabular Impingement, Osteochondritis Dissecans, Hip Fractures
- Trial name
- NCT02664337
- Testing
- Decision tool, Standard treatment information
- Where
- United States
- Volunteers
- 2,310 people
- Sponsor
- Duke University
Chronic Ankle Instability, Lateral Ankle Sprain
Fu's Subcutaneous Needling for Postacute Lateral Ankle Sprain and Prevention of Chronic Ankle Instability
Introduction: Fu's Subcutaneous Needling (FSN) is a new type of acupuncture treatment method based on the subcutaneous tissue sweeping technique, and it has been proven to have a good therapeutic effect on ankle sprain.
- Trial name
- NCT07161427
- Testing
- Fu's Subcutaneous Needling therapy, Ankle joint aids combined with exercise therapy
- Volunteers
- 62 people
- Sponsor
- Guangzhou University of Chinese Medicine
Lateral Malleolus Fracture
A Noninferiority RCT Comparing Operative vs Nonoperative Treatment for ER-stress Positive Weber-B Unimalleolar Fractures
Current gold standard treatment for unstable (those found unstable in external rotation (ER) stress testing Weber B-type, Lauge-Hansen supination-external rotation type IV) ankle fractures is open reduction and internal fixation…
- Trial name
- NCT01758796
- Testing
- Non-operative treatment, Surgery
- Where
- Finland
- Volunteers
- 126 people
- Sponsor
- University of Oulu
Osteoarthritis (OA), Osteoarthritis (OA) of the Knee
Platelet Rich Plasma for Musculoskeletal Conditions
The primary purpose of this study is to follow patients with various musculoskeletal (MSK) conditions over a one-year follow-up period after receiving a platelet rich plasma (PRP) injection, assessing changes in their pain…
- Conditions
- Osteoarthritis (OA), Osteoarthritis (OA) of the Knee, Osteoarthritis (OA) of the Hip, Osteoarthritis (OA) of the Shoulder
- Trial name
- PRP for MSK (NCT07231471)
- Testing
- Platelet Rich Plasma Injection, Platelet Rich Plasma Preparation
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Utah
Sprains and Strains, Contusions
Efficacy and Safety of Etoricoxib in Acute Ankle Sprain: A Double-Blind Comparative Study Among 2 Treatments Protocols
The investigators will study 2 doses of etoricoxib to prove that 60 mg once daily will be non-inferior to etoricoxib 90mg daily (for 14 days) in the treatment of acute ankle sprain in sports.
- Trial name
- NCT00525993
- Testing
- etoricoxib 90mg 14 days, etoricoxib 60mg daily for 14 days
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Núcleo de Estudos em Esportes e Ortopedia, Brazil
Plantar Fasciosis, Achilles Tendinosis
Clinical Evaluation of Placement of Radiofrequency-based Plasma Microdebridement in the Treatment Algorithm for Foot and Ankle Tendinosis and Plantar Fasciosis
To determine the magnitude of improvement for pain and function symptoms over a two year period after enrollment into the registry study in patients presenting with chronic heel pain and receiving standard of care treatment.
- Trial name
- TOPAZ Registry (NCT00420875)
- Testing
- TOPAZ MicroDebrider
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- ArthroCare Corporation
Ankle Fractures
AORIF Complex Ankle Fractures
The aim of this study is to evaluate the intraarticular lesions, to identify fractures specifically at risk for these, and to assess the results following arthroscopically assisted open reduction and internal fixation of complex…
- Trial name
- NCT04033848
- Testing
- Arthroscopic assisted ankle fracture treatment
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Ankle Injuries, Treatment Outcome
Assessment of the Quality of Life of Patients Visiting the Emergency Department of the Saint-Brieuc Hospital Following an Ankle Sprain
Lateral ankle sprains account for nearly 6,500 emergency department visits per day in France. They are clinically classified into three grades, which can be assessed approximately 3-5 days after an acute sprain.
- Trial name
- EntoQuaVie (NCT07054892)
- Testing
- FAAM - Activities of Daily Living (ADL) Subscale
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier de Saint-Brieuc