Clinical trials: Wounds and Injuries, Ankles
Ankle Fractures, Splints
Post Operative Ankle Splint Study - Prospective Multi Center Randomized Controlled Trial
Background: Ankle fractures are some of the most common orthopedic presentations, however, controversy in their management and their post-operative rehabilitation protocols exist.
- Trial name
- PASS (NCT04796168)
- Testing
- Splinting (plaster of paris)
- Where
- Kuwait
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kuwait Institute for Medical Specialization
Wounds and Injuries, Hands, Wounds and Injuries, Wrists
ULD-E (Ultra Low Dose Extremities)
extremity trauma is a frequent reason for emergency room visits. There is an increase in the use of CT scanners in extremity trauma, due to a greater sensitivity of detection than X-rays, particularly for "occult fractures" and…
- Conditions
- Wounds and Injuries, Hands, Wounds and Injuries, Wrists, Wounds and Injuries, Feet, Wounds and Injuries, Ankles
- Trial name
- ULD E (NCT04832490)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Ankle and Hindfoot Arthrodesis
Long-term Safety and Effectiveness of AUGMENT® Bone Graft Compared to Autologous Bone Graft
The objective of this long-term study is to evaluate the long term effectiveness and safety of AUGMENT® Bone Graft vs. autologous bone graft.
- Trial name
- NCT02879149
- Testing
- AUGMENT® Bone Graft, Standard of Care
- Where
- 26 sites in United States, Canada
- Volunteers
- 150 people
- Sponsor
- BioMimetic Therapeutics
Balance; Distorted, Ankle Injury
Neuromuscular Warm-Up Program for Badminton Players
This study aims to develop and evaluate a new warm-up program specifically designed for recreational badminton players. The program focuses on exercises that enhance balance and reduce the risk of ankle injury.
- Trial name
- NWUPFBM (NCT06587516)
- Testing
- Neuromuscular Warmup Program, Traditional Warmup Program
- Where
- Malaysia
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Ankle Injuries and Disorders, Surgery Complications
Postoperative Complications of Ankle Arthroscopy
The goal of this clinical trial is to describe complications that occurred in the year following surgery, based on follow-up surgical consultations and physical therapy sessions.
- Trial name
- ARTHRO2025 (NCT07335133)
- Testing
- Physical therapy and surgery tests and scores
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Clinique Saint Jean, France
Severe Distal Tibia Injury, Severe Ankle Injury
Outcomes Following Severe Distal Tibia, Ankle and/or Foot Trauma: Comparison of Limb Salvage Versus Transtibial Amputation Protocol
The primary aim this prospective longitudinal observational outcomes study is to compare 18 month functional outcomes and health related quality of life (HRQoL) of patients undergoing salvage versus amputation following severe…
- Conditions
- Severe Distal Tibia Injury, Severe Ankle Injury, Severe Foot Injury, Major Soft Tissue Loss
- Trial name
- OUTLET (NCT01606501)
- Where
- 33 sites in United States
- Volunteers
- 664 people
- Sponsor
- Major Extremity Trauma Research Consortium
Sprain, Strain
Ketoprofen 10% Cream for Treatment of Pain Associated With Mild to Moderate Acute Soft Tissue Injury
Imprimis Pharmaceuticals is investigating a proprietary, topical cream formulation consisting of 10% ketoprofen (containing 100 mg of ketoprofen in 1gram of cream) for the local treatment of acute musculoskeletal pain.
- Conditions
- Sprain, Strain, Acute Soft Tissue Injury
- Trial name
- NCT00765700
- Testing
- Topical Ketoprofen 10% Cream
- Where
- United States
- Volunteers
- 364 people
- Sponsor
- Imprimis Pharmaceuticals, Inc.
Ankle Injuries
Muscle Activation in Chronic Ankle Instability and the Effect of an Exercise Programme
This study aims to investigate the activity patterns of the peroneal muscle group, in individuals with a history of chronic ankle instability (CAI) of the ankle injuries compared with individuals without ankle problems.
- Trial name
- NCT02276339
- Testing
- Exercise
- Where
- Ireland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Transcutaneous Electric Nerve Stimulation, Ankle Injuries and Disorders : Chronic Ankle Instability
Echoguided Percutaneous Neuromodulation in the Management of Chronic Ankle Instability in Physically Active Subjects.
The lateral ankle complex sprain is the most prevalent musculoskeletal injury among the general population and athletes and is associated with long-term pain, disability, and high healthcare costs.
- Conditions
- Transcutaneous Electric Nerve Stimulation, Ankle Injuries and Disorders : Chronic Ankle Instability, Exercise Therapy
- Trial name
- NCT05942417
- Testing
- Echoguided percutaneous neuromodulation plus exercise, Strength program
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Escoles Universitaries Gimbernat
Sprains and Strains, Pain
A Study of the Efficacy and Safety of Tramadol HCl/Acetaminophen, Hydrocodone Bitartrate/Acetaminophen and Placebo in Patients With Pain From an Ankle Sprain With a Partial Torn Ligament
The purpose of this study is to explore the pain-relieving effects and safety of two analgesic treatment regimens as compared to placebo in patients experiencing acute musculoskeletal pain.
- Trial name
- NCT00236535
- Volunteers
- 603 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Negative Pressure Wound Therapy, Vacuum Therapy
Negative Pressure Wound Therapy for Surgical Wounds of the Foot and Ankle
Prophylactic use of Negative Pressure Wound Therapy (NPWT) on surgical wounds following lower extremity orthopedic trauma to prevent infectious complications.
- Conditions
- Negative Pressure Wound Therapy, Vacuum Therapy, Closed Incisions
- Trial name
- NEWTON (NCT02739191)
- Testing
- PICO, Smith & Nephew
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- J.C. Goslings
Ankle Injury or Chronic Trauma to the Ankle
CETI-ANKLE: Cetilar®️ in Patients With Ankle Injury or Chronic Trauma to the Ankle
The purpose of this study is to assess the safety, tolerability and efficacy of Cetilar®
- Trial name
- NCT06137820
- Testing
- Cetilar® (topical cream)
- Where
- 3 sites in Georgia, Italy
- Volunteers
- 80 people
- Sponsor
- Pharmanutra S.p.a.
Deep Vein Thrombosis, Pulmonary Embolism
Prophylaxis of Thromboembolic Complications Trial: Thromboprophylaxis Needed in Below Knee Plaster Cast Immobilization for Ankle and Foot Fractures
Objective: The purpose of this study is to determine the need for thromboprophylaxis in patients with a fracture of the lower extremity being treated conservatively in a below-knee plaster cast and to assess if both of the two…
- Trial name
- PROTECT (NCT00881088)
- Testing
- Nadroparin, Fondaparinux
- Where
- 5 sites in Netherlands
- Volunteers
- 669 people
- Sponsor
- Red Cross Hospital Beverwijk
Fracture Dislocation of Ankle Joint, Fracture Leg
Single Shot Exparel vs Catheters in Lower Extremity Trauma
This study will compare the use of single-shot Exparel, a long-acting local anesthestic, with the use of catheters that deliver a continuous flow of the short-acting local anesthetic ropivacaine.
- Conditions
- Fracture Dislocation of Ankle Joint, Fracture Leg, Fracture Femur, Fracture Lower Leg
- Trial name
- NCT07221019
- Testing
- Bupivacaine, Exparel + Bupivacaine
- Where
- United States
- Sponsor
- George Washington University
Ankle and or Hindfoot Injury
The Effect of Needle Placement on Muscle Stiffness, Gait, Balance, Pain and Functional Outcomes in Individuals With Injury to the Ankle and/or Hindfoot
The purpose of this randomized controlled trial is to assess the effect of DN at either the site of the identified myofascial trigger point/s (MTrP) of in the same muscle, but away from the MTrP site/s in individuals with ankle…
- Trial name
- NCT04487327
- Testing
- Dry Needling
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Regis University
Ankle Fracture
Bedside Ultrasound in the Diagnosis of Ankle Fractures in Children
Objectives: A lot of children who injure their ankles come to the emergency department for an evaluation, and often an X-ray of the ankle is obtained to determine if a bone fracture is present.
- Trial name
- NCT01341015
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Rhode Island Hospital
Ankle Sprains, Lateral Ankle Sprain
Study of the AxisBoard Single-Leg Balance Board in Adults With Lateral Ankle Sprain
The goal of this study is to learn whether a 28-day home exercise program using the AxisBoard Single-Leg Balance Board improves ankle function in adults who are still having symptoms 6 weeks to 6 months after a lateral (outer)…
- Trial name
- NCT07860125
- Testing
- AxisBoard Single-Leg Balance Board
- Volunteers
- 80 people
- Sponsor
- DITU Inc.
Pain, Postoperative, Ankle Fracture Surgery
Buprenorphine as a Post-operative Analgesic in Opioid-Naive Patients After Ankle Fracture Surgery
Addictive full-agonist opioids, like oxycodone and hydrocodone, are often used to treat pain after surgery. However, these full-agonist opioids can be very addictive.
- Conditions
- Pain, Postoperative, Ankle Fracture Surgery, Opioid Use Disorder, Opioid Dependence
- Trial name
- BAFA (NCT06949826)
- Testing
- Buprenorphine Transdermal System
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Jenna-Leigh Wilson
Sprain and Strain of Ankle
Effect of Kinesiotaping on Ankle Stability
Ankles sprains are the most popular injuries in basketball players. They are traumatic injuries, which happen most of the time in specific situations, like landing on another player's foot, or during changes of direction.
- Trial name
- NCT02115217
- Testing
- Leukotape K
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Clinique Romande de Readaptation
Morphological Analysis and Classification, Posterior Malleolar Fractures
Morphological Analysis and Classification of Posterior Malleolar Fractures Based on CT Scans
The study was to propose a classification system of posterior malleolar fractures by fracture lines with the use of CT scans, including 3D CT reconstruction, which can better understand morphological characteristics, analyze the…
- Conditions
- Morphological Analysis and Classification, Posterior Malleolar Fractures, CT Scans
- Trial name
- NCT05159258
- Volunteers
- 128 people
- Sponsor
- Peking University People's Hospital