Clinical trials: Wounds and Injuries, Ankles
Ankle Injury or Chronic Trauma to the Ankle
CETI-ANKLE: Cetilar®️ in Patients With Ankle Injury or Chronic Trauma to the Ankle
The purpose of this study is to assess the safety, tolerability and efficacy of Cetilar®
- Trial name
- NCT06137820
- Testing
- Cetilar® (topical cream)
- Where
- 3 sites in Georgia, Italy
- Volunteers
- 80 people
- Sponsor
- Pharmanutra S.p.a.
Deep Vein Thrombosis, Pulmonary Embolism
Prophylaxis of Thromboembolic Complications Trial: Thromboprophylaxis Needed in Below Knee Plaster Cast Immobilization for Ankle and Foot Fractures
Objective: The purpose of this study is to determine the need for thromboprophylaxis in patients with a fracture of the lower extremity being treated conservatively in a below-knee plaster cast and to assess if both of the two…
- Trial name
- PROTECT (NCT00881088)
- Testing
- Nadroparin, Fondaparinux
- Where
- 5 sites in Netherlands
- Volunteers
- 669 people
- Sponsor
- Red Cross Hospital Beverwijk
Ankle Injury
The Effect of Balance Training on Unloading Reaction in Individuals With Functional Ankle Instability
The aim of this study is to determine the effect of a balance training intervention on the change in hyper-reactivity to unloading reaction, ankle joint laxity, ankle joint proprioception and evertor muscle weakness in…
- Trial name
- NCT00703456
- Testing
- Balance Training
- Where
- United States
- Sponsor
- University of Kansas Medical Center
Ankle Injuries
Hydrotherapy With Hydrogen-rich Water vs. RICE Protocol Following Acute Ankle Sprain
The traditional treatment of soft tissue injuries consists of the RICE protocol - rest, ice, compression, and elevation, followed for up to 72 hours after a trauma.
- Trial name
- HRWAAC (NCT04167202)
- Testing
- Hydrogen-rich water, RICE
- Where
- Serbia
- Volunteers
- 18 people
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Ankle Sprains
Effects of Mobilization Versus Manipulation on Function in Participants Reporting CAI
The investigator's purpose is to compare the effects of talocrural joint mobilization with movement versus thrust mobilization on functional performance in subjects reporting chronic ankle instability (CAI).
- Trial name
- NCT03918473
- Testing
- Mobilization with Movement, Thrust Mobilization
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Shenandoah University
Lateral Malleolus Fractures
Double Compression Screw Fixation for Symptomatic Non-union of Lateral Malleolar Ankle Fractures
The aim of this prospective clinical trial study is to evaluate the clinical and radiological outcomes of treating non-union of the lateral malleolar ankle fractures by double compression screw fixation technique.
- Trial name
- NCT07539922
- Testing
- Double Compression Screw Fixation for Symptomatic Non-union of Lateral Malleolar Ankle Fractures
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Sohag University
Syndesmotic Injury of the Ankle
Tightrope or Screw Fixation of Acute Tibiofibular Syndesmotic Injury
Syndesmotic injuries are common and often associated with unstable ankle fractures. The most common treatment is with a syndesmotic screw through the fibula and tibia which is later removed, usually after 10-12 weeks.
- Trial name
- TIGHTROPE-SS (NCT01275924)
- Testing
- Tightrope Syndesmosis Repair Kit, Syndesmotic screw
- Where
- 2 sites in Norway
- Volunteers
- 97 people
- Sponsor
- Sykehuset Asker og Baerum
Ankle Sprain
Effect of Elastic Bandage on Balance in Chronic Ankle Instability
Purpose: To report the immediate and prolonged (one week) effects of elastic bandage on balance control in subjects with chronic ankle instability.
- Trial name
- NCT02682303
- Testing
- Elastic Bandage (Idealplast C®), Pretape cramer® (non standarized tape)
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- Universidad Rey Juan Carlos
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
Quadriceps Tendon vs Peroneus Longus Tendon in ACL Reconstruction
This prospective randomized clinical trial aims to compare quadriceps tendon and peroneus longus tendon autografts in anterior cruciate ligament reconstruction.
- Trial name
- NCT07671729
- Testing
- Anterior Cruciate Ligament Reconstruction Using Quadriceps Tendon Autograft, Anterior Cruciate Ligament Reconstruction Using Peroneus Longus Tendon Autograft
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Acibadem University
Ankle Injuries, Foot Injuries
Ankle Trauma: an Emergency Nurse Assessment Study
The ankle and/or foot injuries incidence is high. Lateral ankle sprains are most common diagnosis, while fractures represent less than 15% of final diagnosis.
- Conditions
- Ankle Injuries, Foot Injuries, Diagnosis, Treatment
- Trial name
- ATENA (NCT04126837)
- Testing
- Diagnosis and treatment
- Where
- France
- Volunteers
- 66 people
- Sponsor
- University Hospital, Grenoble
Osteoporotic Fractures, Hip Fractures
Prediction and Secondary Prevention of Fractures
The purpose of this study is to investigate patient related factors that contribute to increased risk of recurrent fractures and to investigate patient adherence to prescribed anti-osteoporotic drugs.
- Conditions
- Osteoporotic Fractures, Hip Fractures, Wrist Fractures, Ankle Fractures
- Trial name
- NOFRACTsub (NCT02608801)
- Where
- 6 sites in Norway
- Volunteers
- 840 people
- Sponsor
- Oslo University Hospital
Ankle Fractures
Ziptight or Tricortical Screw Fixation of Acute Tibiofibular Syndesmotic Injury
Treatment of syndesmotic injury with Weber C fracture. A randomized study comparing ZipTight suture endobutton and one tricortical 3,5 mm syndesmotic screw.
- Trial name
- S16 (NCT02930486)
- Testing
- ZipTight suture endobutton, Tricortical 3.5 mm syndesmotic screw
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Vestre Viken Hospital Trust
Ankle Injuries, Ankle Sprains
Ankle Instability Using Foot Intensive Rehabilitation
The overall objective of this study is to examine the effects of a 6-week foot-intensive rehabilitation (FIRE) program on lateral ankle sprain (LAS) re-injury rates, CAI symptoms, sensorimotor function, and self-reported…
- Trial name
- FIRE (NCT04493645)
- Testing
- Standard of Care Rehabilitation (SOC), Foot Intensive Rehabilitation (FIRE)
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Matthew Hoch
Ankle Injuries
Early Weightbearing and Mobilization Versus Non-Weightbearing and Mobilization in Unstable Ankle Fractures
The primary objective of the investigators randomized controlled trial is to determine if early protected weightbearing and ankle range of motion after surgical treatment (open reduction internal fixation - ORIF) for ankle…
- Trial name
- NCT01196338
- Testing
- Early weight-bearing and range of motion exercises, non-weight bearing, no range of motion
- Where
- 2 sites in Canada
- Volunteers
- 110 people
- Sponsor
- University of Toronto
Ankle Fracture - Lateral Malleolus, Deltoid Ligament; Sprain (Strain) (Ankle)
Deep Deltoid Ligament Integrity in Weber B Ankle Fractures - Mini-invasive Arthroscopic Evaluation.
Prospective cohort study to evaluate the use of a NanoScopic procedure to assess deltoid ligament injuries with outcomes measured at baseline, 6 weeks, 12 weeks, 1 year and 2 years.
- Conditions
- Ankle Fracture - Lateral Malleolus, Deltoid Ligament; Sprain (Strain) (Ankle), Ankle Fractures
- Trial name
- NCT04674046
- Testing
- Nonoperative treatment, Operative treatment, Standardized education
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Ostfold Hospital Trust
Ankle Sprains
Manual Therapy, Kinesiotape and Strength Training in Soccer Players With Recurrent Ankle Sprains
Introduction. The ankle sprain is one of the most prevalent injuries in soccer players. The muscle strength deficit is one of the variables that can most influence the development of a sprain.
- Trial name
- NCT04257916
- Testing
- Experimental, Manual therapy group
- Where
- Spain
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Investigación en Hemofilia y Fisioterapia
Balance; Distorted, Ankle Injury
Neuromuscular Warm-Up Program for Badminton Players
This study aims to develop and evaluate a new warm-up program specifically designed for recreational badminton players. The program focuses on exercises that enhance balance and reduce the risk of ankle injury.
- Trial name
- NWUPFBM (NCT06587516)
- Testing
- Neuromuscular Warmup Program, Traditional Warmup Program
- Where
- Malaysia
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Achilles Tendon Rupture, Ankle Fractures
Swedish Multicenter Trial of Outpatient Prevention of Leg Clots
Lower limb immobilization is associated with high risk of complications, i.e. venous thromboembolism (VTE) and failed healing. Pharmacoprophylaxis of VTE is in leg-immobilized patients, however, low- or non-effective and…
- Conditions
- Achilles Tendon Rupture, Ankle Fractures, Venous Thromboembolism
- Trial name
- StopLegClots (NCT03259204)
- Testing
- Adjuvant IPC
- Where
- Sweden
- Volunteers
- 1,400 people
- Sponsor
- Karolinska University Hospital
Intra-Articular Fractures
Effect of Early Saline Lavage on Synovial Fluid Composition Following Intra Articular Ankle Fractures
The purpose of this study is to examine the effect of early, percutaneous, intra-articular saline lavage on the undiluted synovial fluid microenvironment during the acute phase following intra-articular fracture of the human…
- Trial name
- NCT05465382
- Testing
- Saline Lavage, No intra-articular saline lavage, Lidocaine - intra-articular injection
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Duke University
Musculoskeletal Pain, Ankle Injuries
Video Aided Mindful Deep Breathing for Pain Management
Chronic ankle instability (CAI) is the most common musculoskeletal injury in sports and the rate of CAI accounts for 85% of ankle injuries.
- Conditions
- Musculoskeletal Pain, Ankle Injuries, Joint Instability
- Trial name
- NCT04812158
- Testing
- standard ankle physiotherapy or rehabilitation for chronic ankle instability
- Where
- Malaysia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universiti Tunku Abdul Rahman