Clinical trials: Wounds and Injuries, Ankles
Spinal Cord Injury
BCI-Guided Tibialis Anterior FES for Gait Training in Spinal Cord Injury
This study aims to investigate the effectiveness of Brain-Computer Interface (BCI)-guided Functional Electrical Stimulation (FES) in improving muscle activation and gait kinematics in individuals with Spinal Cord Injury (SCI).
- Trial name
- NCT07768930
- Testing
- Ankle Dorsiflexion Rehabilitation
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- Santos Dumont Institute
Ankle Fracture, Bimalleolar, Ankle Fracture, Trimalleolar
Use of Weightbearing Radiographs to Determine Treatment of bi- and Trimalleolar Ankle Fractures
The aim of this study is to evaluate the outcomes after non-operative treatment of weightbearing stable bi-and trimalleolar ankle fractures.
- Trial name
- NCT05765929
- Testing
- Non-operative treatment
- Where
- Norway
- Volunteers
- 29 people
- Sponsor
- Ostfold Hospital Trust
Fractures Bone
ANKLE TRAUMA Diagnostic Value of Ultrasound Compared to Standard Radiography in the Detection of Fractures
To investigate the diagnostic value of ultrasound performed by a lay experimenter compared to standard radiographic imaging (or standard x-ray) in the detection of fractures in patients with closed acute ankle trauma and positive…
- Trial name
- NCT05528432
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Injury; Muscle, Ankle, and Foot, Multiple
Effect of Preoperative Mobility Device Training on Postoperative Fall Incidence
The purpose of this study is to determine whether preoperative mobility device training is beneficial in reducing incidence of postoperative falls in patients undergoing elective foot and ankle surgery requiring a postoperative…
- Trial name
- NCT03857945
- Testing
- Preoperative mobility device(s) training
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Alabama at Birmingham
Syndesmotic Injuries
Treatment of Syndesmotic Disruption With Anatomic Distal Tibiofibular Ligament Augmentation
The primary objective is to evaluate indications and outcomes of operative fixation of syndesmotic injuries, at least in part, with direct anatomic augmentation in acute and subacute traumatic cases.
- Trial name
- NCT04933045
- Testing
- Arthrex InternalBrace
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- St. Clair Orthopaedics
Posterior Malleolus Fractures, Ankle Fractures
Weber B Ankle Fractures With Associated Posterior Malleolus Fracture
Ankle fractures constitute 9% of all fractures and have an incidence of approximately 187 per 100,000 persons per year in Norway.
- Conditions
- Posterior Malleolus Fractures, Ankle Fractures, Syndesmotic Injuries, Patient Reported Outcome Measure
- Trial name
- PMFIX (NCT05413707)
- Testing
- Fixation of the posterior malleolus fractures, Fixation of lateral and/or medial malleolus fractures, Syndesmotic fixation
- Where
- Norway
- Volunteers
- 198 people
- Sponsor
- Haukeland University Hospital
Ankle Disorders Injuries
Urdu Translation And Cross-Cultural Validation of the Foot And Ankle Disability Index
The goal of this Cross-cultural validation study is to Urdu translate and cross-cultural validation of Foot and Ankle Disability Index for the Patients with Chronic Ankle Instability.
- Trial name
- NCT05732636
- Testing
- Validation study
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Sehat Medical Complex
Ankle Injuries, Risk of Falling
Weight Variations Impacts on the Ankle of the Child
Obesity is a global health problem. It changes the measurement of the human body and makes a big change to move the body. The increased weight and mass change the way the limbs and whole body generate and react to force Excess…
- Conditions
- Ankle Injuries, Risk of Falling, Stability
- Trial name
- NCT05074511
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Delta University for Science and Technology
Ankle Injuries, Foot Injuries and Disorders
Weight Change With Controlled Ankle Movement (CAM) Boot Use
The purpose of the study is to determine if patients wearing a CAM boot have a change in weight compared to patients who wear a CAM boot and are provided nutritional guidelines and perform upper body exercises.
- Conditions
- Ankle Injuries, Foot Injuries and Disorders, Body Weight Changes
- Trial name
- CAM (NCT05692401)
- Testing
- Nutrition and Exercise Instruction
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Nell Blake, DPM
Older Adults, Range of Motion
Comparison of The Acute Effects of Different Stretching Methods on Ankle Joint Range In Healty Older Adults
Introduction: To compare the acute effects of different stretching methods on ankle joint range of motion (ROM) in older adults. Methods: A total of 78 subjects aged 65 years and older were randomly divided into three groups.
- Conditions
- Older Adults, Range of Motion, Ankle Injuries
- Trial name
- NCT05130372
- Testing
- Static Stretching Method Group, PNF Stretching Method Group, Myofascial Relaxation Method Group- Roller Massage
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Lateral Ankle Sprain
The Effects of Gentle Movements at the Ankle in Individuals With Diminished Range of Motion
The purpose of this study is the examine the effects of gentle movements applied to the ankle joint and stretching on self-reported function, ankle motion and stiffness in individuals who have suffered from an ankle sprain within…
- Trial name
- NCT01119092
- Testing
- Grade IV AP joint mobilizations
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Virginia
Ankle Sprain
Proof-of-concept Study of NSAID Hydrogel Patch in Treatment of Acute Pain
The safety and the efficacy of the Esflurbiprofen Hydrogel Patch will be assessed in comparing with placebo in the treatment of acute pain due to ankle sprain
- Trial name
- NCT02729207
- Testing
- Esflurbiprofen Hydrogel Patch
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Teikoku Seiyaku Co., Ltd.
Ankle Sprain
Evaluation of Therapeutic Effects of LED (627 +/- 10nm) The Initial Phase of the Ankle Sprains Treatment
The purpose of this study is to evaluate the therapeutic effects of the LED (627 +/- 10 nm) with respect to the localized pain and local swelling of ankle sprains in the initial phase.
- Trial name
- NCT02433964
- Testing
- Grupo LED
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade do Vale do Paraíba
Ankle Fractures
Telerehabilitation Following Ankle Fractures
Background and Purpose: Ankle fractures represent one of the most common fractures in North America. Surgical fixation is often required in the presence of dislocation or instability and has been shown to have a high rate of…
- Trial name
- NCT04235907
- Testing
- Telerehabilitation, Standard rehabilitation
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Johns Hopkins University
Bimalleolar Ankle Fractures
CMF Bone Stimulation as Adjunct to Surgical Treatment of Ankle Fractures
The OL1000 is intended to be used as a non-invasive adjunctive treatment for adult males or females that have sustained a closed, unstable ankle fracture that requires surgical treatment for stabilization.
- Trial name
- NCT02688855
- Testing
- Active Combined Magnetic Field OL1000 Bone Growth Stimulator
- Where
- 9 sites in United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Encore Medical, L.P.
Ankle Sprain
Ketoprofen Gel vs Placebo in Children With Ankle Sprain
The aim of this study is to analyse the effect of ketoprofen gel in children presented with ankle sprain to the emergency department.
- Trial name
- NCT02491736
- Testing
- Ketoprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Akdeniz University
Sprains and Strains, Contusions
Efficacy and Safety of Etoricoxib in Acute Ankle Sprain: A Double-Blind Comparative Study Among 2 Treatments Protocols
The investigators will study 2 doses of etoricoxib to prove that 60 mg once daily will be non-inferior to etoricoxib 90mg daily (for 14 days) in the treatment of acute ankle sprain in sports.
- Trial name
- NCT00525993
- Testing
- etoricoxib 90mg 14 days, etoricoxib 60mg daily for 14 days
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Núcleo de Estudos em Esportes e Ortopedia, Brazil
Ankle Sprains
Addressing Neuromuscular Deficits for Improved Outcomes in Ankle Rehabilitation
The purpose of this project is to compare a novel sensorimotor ankle rehabilitation training (SMART) protocol for Lateral ankle sprains (LASs) against a standard of care (SOC) protocol to determine if it is more successful at…
- Trial name
- NCT03663361
- Testing
- SMART Intervention, Standard of Care Intervention
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- Phillip Gribble
Severe Distal Tibia Injury, Severe Ankle Injury
Outcomes Following Severe Distal Tibia, Ankle and/or Foot Trauma: Comparison of Limb Salvage Versus Transtibial Amputation Protocol
The primary aim this prospective longitudinal observational outcomes study is to compare 18 month functional outcomes and health related quality of life (HRQoL) of patients undergoing salvage versus amputation following severe…
- Conditions
- Severe Distal Tibia Injury, Severe Ankle Injury, Severe Foot Injury, Major Soft Tissue Loss
- Trial name
- OUTLET (NCT01606501)
- Where
- 33 sites in United States
- Volunteers
- 664 people
- Sponsor
- Major Extremity Trauma Research Consortium
Chronic Ankle Instability, CAI, Ankle Sprain
Validation of a Portable Ankle Arthrometer
The purpose of this study is to assess the validity and reliability of a prototype portable ankle arthrometer in various populations. There are two aims to this study.
- Conditions
- Chronic Ankle Instability, CAI, Ankle Sprain, Healthy
- Trial name
- NCT07163897
- Testing
- Cobra Ankle Arthrometer
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Virginia