Clinical trials: Wounds and Injuries
SCI
AIH for Spinal Cord Repair
Contusive cervical spinal cord injury (cSCI) impairs upper limb function (reach-and-grasp) which limits daily-life activities and thus decreases the quality of life.
- Trial name
- NCT03780829
- Testing
- hypoxia, D-cycloserine, exercise training
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Magnetic Resonance Imaging, Neuronal Activity
Acute Pain Memory Among Former Burned: Exploration of fMRI.
Pain is complex phenomenon misunderstood in spite of medical progress and neurosciences. That's why the relief of chronic pain is only partial for a lot of infection as arthrosis, chronic back pain, headaches or neuropathic pain.
- Trial name
- EXPLO-DMA (NCT03224975)
- Testing
- fMRI
- Where
- France
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Traumatic Brain Injury, Sports Injury
Blood-based Biomarkers for the Prognosis of Sports Related Concussion
The diagnosis of sports related concussion still relies heavily on a subjective assessment. In this study the investigators want to assess the prognostic value of blood-based biomarkers with recovery from concussive episodes over…
- Conditions
- Traumatic Brain Injury, Sports Injury, Concussion, Mild
- Trial name
- NCT04485494
- Testing
- Biochemical Analysis of Blood Biomarkers
- Where
- Ireland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Rotator Cuff Tear
Use of Graft Jacket for Rotator Cuff Repair
This study is to evaluate the safety and effectiveness of GraftJacket, a human tissue product used in fixing large and massive reparable rotator cuff tears.GraftJacket allograft (Wright Medical Technology, Inc., Arlington, TN) is…
- Trial name
- NCT00456781
- Testing
- Augmentation, Rotator Cuff Repair without augmentation
- Where
- 7 sites in United States, Canada
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Stryker Trauma and Extremities
Hip Fractures, Family
Caregivers' eCourse for Recovery After Hip Fracture
In this two part study, we will seek 1. general feedback on the feasibility of an online education and skill development program for family/caregivers of older adults recovering from a surgically repaired low-trauma hip fracture.
- Trial name
- NCT03814928
- Testing
- Caregivers eCourse
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Spinal Cord Injury
Mechanisms of Orthostatic Intolerance in Spinal Cord Injured Individuals and Following Bed Rest
The primary purpose of this study is to investigate the relationship between the extent of neurologic (nerve) impairment in patients with spinal cord injuries and how well the nerves passing down the spine to the heart and blood…
- Trial name
- NCT00175773
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Oxygen Toxicity, Pulmonary Injury
Hyperoxia Induced Pulmonary Inflammation and Organ Injury: a Human in Vivo Model
Oxygen is the most commonly administered therapy in critical illness. Accumulating evidence suggests that patients often achieve supra-physiological levels of oxygenation in the critical care environment.
- Conditions
- Oxygen Toxicity, Pulmonary Injury, Acute Lung Injury
- Trial name
- NCT05414370
- Testing
- Liquid oxygen, medical air
- Where
- United Kingdom
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Belfast Health and Social Care Trust
Athletic Injuries, Sport Injuries
Rise With Resilience
The objective of this study is to investigate differences in postoperative pain, physical health, and mental health outcomes between participants receiving evidence-based mindfulness training and those who do not.
- Trial name
- NCT07217275
- Testing
- Community Resiliency Model (CRM), Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Emory University
Anterior Cruciate Ligament (ACL) Injury
The Influence of Demographic Parameters and ACL Injury on the Association Among Clinical, Functional and Biomechanical Parameters
This retrospective study aims at analysing demographics and clinical, functional and biomechanical outcomes in patients after ACL injury (conservative therapy and/or surgery) in patients of different ages and healthy controls.
- Trial name
- MechBRACE (NCT05644275)
- Testing
- Data collection (demographic, clinical, functional and biomechanical outcomes in patients after ACL injury (conservative therapy and/or surgery) in patients of different ages and healthy controls)
- Where
- Switzerland
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Car Seats, Injuries
Evaluating Models for Dissemination of Injury Prevention Information in the Pediatric Emergency Department Setting
This study examines the Pediatric Emergency Department as a location for increasing safe car seat practices by parents who are not restraining their children appropriately in motor vehicles.
- Trial name
- NCT00476255
- Testing
- Enhanced Standard Care (ESC), Brief Motivational Intervention (BMI)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rhode Island Hospital
Shoulder Pain, Rotator Cuff Impingement Syndrome
Bupivacaine or Radiofrequency for Shoulder Pain
Comparative study between pulsed radiofrequency in suprascapular nerve or bupivacaine block for chronic shoulder pain
- Conditions
- Shoulder Pain, Rotator Cuff Impingement Syndrome, Impingement Syndrome, Adhesive Capsulitis
- Trial name
- NCT05778422
- Testing
- Suprascapular nerve block with bipuvacaine, Pulsed radiofrequency
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Postoperative Pain Management
A Comparative Study Between Different Volumes During Erector Spinae Block for Pain Control
Since its first description by Forero et al. there have been many articles and case reports including an increasingly number of indications for the ESP block: chronic and acute pain treatment, rib fractures management in the…
- Trial name
- NCT04371341
- Testing
- erector spinae block by 0.25% bupivacaine
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acute Radiation Syndrome
A Clinical Trial to Evaluate Safety, Tolerability and Pharmacokinetic/Pharmacodynamic Characteristics of KMRC011
This trial is designed to evaluate the safety, tolerability, pharmacokinetic and pharmacodynamic of KMRC011 injection in healthy adult volunteers.
- Trial name
- NCT03585803
- Where
- South Korea
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Intron Biotechnology, Inc.
Bone Fracture, Fresh Fracture
Sustained Acoustic Medicine (SAM) for Symptomatic Treatment of Pain Related to Bone Fracture
The purpose of this study is to assess the ability of long-duration low-intensity therapeutic ultrasound (LITUS) to alleviate bone-fracture related pain over a 12-week period.
- Trial name
- NCT05883241
- Testing
- Sustained Acoustic Device with 2.5% Diclofenac Patch, 2.5% Diclofenac Patches
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- ZetrOZ, Inc.
Osteoporosis, Achlorhydria
Does Omeprazole Decrease Intestinal Calcium Absorption?
The purpose of this study is to measure the effect of omeprazole on intestinal calcium absorption in postmenopausal women.
- Conditions
- Osteoporosis, Achlorhydria, GERD, Hip Fracture
- Trial name
- NCT00582972
- Testing
- Omeprazole
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Fibrosis, Scarring
High Fluence Light Emitting Diode-Red Light (LED-RL) in Human Skin
The goal of this study is to establish the safety of high fluence LED-RL from 160 J/cm2 up to 640 J/cm2 in healthy subjects. The hypothesis is that high fluence LED-RL phototherapy is safe in human skin.
- Conditions
- Fibrosis, Scarring, Scar, Wounds
- Trial name
- NCT02630303
- Testing
- LED-RL Phototherapy, Mock Therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jared Jagdeo, MD, MS
Femur Fracture
Effect of Preoperative Carbohydrate Loading in Femur Fracture
Femur fracture is very common in older people. It makes the people bedridden for long time at hospital. The fracture of femur is generally managed by the surgical procedure.
- Trial name
- NCT04838366
- Testing
- Carbohydrate loading
- Where
- Nepal
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Armed Police Force Hospital, Nepal
Neonatal Encephalopathy
Follow-up of Inflammatory Responses and Multiorgan Outcomes FoLlowing Neonatal Brain injurY
Babies who have brain injury also frequently have involvement of their kidneys, lung and heart. Although clinical care in the neonatal period is well defined there are few guidelines and evidence for developmental, heart and…
- Trial name
- FIREFLY (NCT04816331)
- Testing
- Medical records and clinical measurements
- Where
- 5 sites in Ireland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Leg Injuries
Core Stability Measures as a Risk Factor for the Development of Lower Extremity Injuries in Physical Education Students
Male and female physical education students were subjected to a clinical test battery comprised of valid and reliable tests to measure different aspects of core stability at the start of the study.
- Trial name
- NCT03343379
- Testing
- Core stability tests
- Where
- Belgium
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University Ghent
Hearing Loss, Sensorineural, Hearing Loss, Conductive
Wide Frequency Band Test of Hearing in Veterans
The accurate assessment of auditory status is critical for planning treatment for Veterans with hearing loss to include medical and audiological management.
- Conditions
- Hearing Loss, Sensorineural, Hearing Loss, Conductive, Hearing Loss, Mixed Conductive-Sensorineural, Otosclerosis
- Trial name
- CWTBAFV (NCT02019888)
- Where
- 2 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
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