Clinical trials: Wrinkle
Wrinkle, Periorbital
Clinical Study Evaluating the Safety and Effectiveness of The Tixel Fractional System in The Treatment of Periorbital Wrinkles
A Prospective, Multicenter, Single-Arm Clinical Study of 51 study subjects who are seeking a procedure to reduce the appearance of the peri-orbital wrinkles.
- Conditions
- Wrinkle, Periorbital, Tixel 2, Fractional
- Trial name
- NCT04639713
- Testing
- Tixel 2
- Where
- 3 sites in United States, Israel
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Novoxel Ltd.
Wrinkle, Spot Pigmented
Skin Rejuvenation With Topical Extract and Other Nutraceuticals
Hemp extract has been shown in several pre-clinical and clinical studies to have anti-aging effects on the skin through anti-oxidant and anti-inflammatory effects, in addition resveratrol, thyme and caffeine have been shown to…
- Conditions
- Wrinkle, Spot Pigmented, Lines Skin
- Trial name
- NCT05734703
- Testing
- Nutraceutical Topical
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical Life Care Planners, LLC
Nasolabial Fold Improvement
Efficacy and Safety of Injection With VINCI Plus Hyaluronic Acid Filler
This clinical trial is intended to evaluate the efficacy and safety of injection with VINCI Plus as compared to Restylane-L® in correction of nasolabial fold.
- Trial name
- NCT01918839
- Testing
- VINCI Plus, Restylane-L
- Where
- 2 sites in South Korea
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- D.med
Décolletage
Sculptra for Décolletage Crepiness and Wrinkling
The purpose of this study is to evaluate the safety and efficacy of Sculptra as a volume agent to improve décolletage crepiness and wrinkling.
- Trial name
- NCT03508973
- Testing
- Sculpta
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Skin Laser & Surgery Specialists
Improvement of Wrinkles/Elastosis and/or Pigmentation
Impact of M22 Synergistic Sequential Treatment (SST)
Up to 40 healthy subjects at 2 sites, age 30-65 year old with Fitzpatrick-Elastosis score of 3-6 and mild to moderate age/sun-related facial pigmentation that wish to improve their facial skin appearance.
- Trial name
- NCT02032771
- Testing
- M22 IPL and ResurFX
- Where
- 2 sites in United States, Germany
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Lumenis Be Ltd.
Skin Laxity
SofWave Treatment to Lift Lax Tissue in the Submental and Neck Zones and to Lift the Eyebrow
Open-label, non-randomized, prospective, multi-center, self-controlled clinical study with masked evaluation.
- Trial name
- NCT04969380
- Testing
- Sofwave
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD
Skin Aging
Clinical Trial to Assess Efficacy, Safety and Tolerability of Botulinum Toxin A (Xeomin®) in Treatment of Expression Wrinkles in the Upper Third of the Face
The purpose of this study is to determinate whether Xeomin® (Botulinum toxin Type A) is safe, effective and tolerable in woman aged 30 to 50 years old for treatment of mild, moderate or severe expression lines (wrinkles) in the…
- Trial name
- XEO-001/07 (NCT00986570)
- Testing
- Botulinum Toxin A
- Where
- Brazil
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Biolab Sanus Farmaceutica
Laxity; Skin
Pivotal Study to Evaluate the Safety and Efficacy of a Micro-coring Device Treating Moderate to Severe Facial Wrinkles
Study evaluating the safety and efficacy of a micro-coring device for the treatment of moderate to severe cheek wrinkles.
- Trial name
- NCT03573271
- Testing
- MCD
- Where
- 5 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cytrellis Biosystems, Inc.
Wrinkles
Radial Diffusion of the Botulinum Toxin Type A (Botox®): Electromyographic Evaluation of the Frontal Muscle
This study evaluates the diffusion area (cephalic, lateral, medial and caudal points) of the botulinum toxin type A in the frontal muscle for usual concentrations and dilutions of the drug.
- Trial name
- NCT01297634
- Testing
- Botulinum Toxin Type-A (day 0)
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Ivo Pitanguy Institute
Wrinkle, Nasolabial Fold
RHA® 4 NLF Cannula
This is a randomized, controlled, single-blinded, within-subject (split-face), multicenter, prospective study to investigate whether RHA®4 injected in NLFs with a cannula is non-inferior to RHA®4 injected in NLFs with a sharp…
- Conditions
- Wrinkle, Nasolabial Fold, Aging
- Trial name
- NCT04754646
- Testing
- Split-face injection of RHA® 4 with a cannula into a single NLF., Split-face injection of RHA® 4 with a needle (TSK 27G x ½") into the contralateral NLF.
- Where
- 4 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Wrinkle
The Effects of a 5-Step Skin Regimen on Pigmentation and Appearance Related Biophysical Properties
This study is to analyze the effects of a 5-step skin care regimen on various skin parameters such as pigmentation, and firmness and elasticity of the skin around the eyes.
- Trial name
- NCT05688527
- Testing
- Cleansing Balm, Toning Essence, Facial Serum
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Aging, Botulinum Toxin
The Impact of Age on Botulinum Toxin Potency in Facial Rhytides Treatment
Botulinum toxin is approved by the FDA for the treatment of facial wrinkles. Patients are usually older than 45 years and their main demand is to treat pre-existing facial wrinkles.
- Conditions
- Aging, Botulinum Toxin, Facial Wrinkles
- Trial name
- NCT03836638
- Testing
- 30 Units of botulinum toxin, 50 Units of botulinum toxin
- Where
- Lebanon
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- St Joseph University, Beirut, Lebanon
Collagen Degeneration, Wrinkle
The Effects of Almond on Facial Skin Collagen and Wrinkles
Investigate the effects of almond consumption on collagen production, elastin levels, wrinkles, and pigmentation among premenopausal women and postmenopausal women belonging to all Fitzpatrick skin types.
- Conditions
- Collagen Degeneration, Wrinkle, Pigmentation, Elastic Skin
- Trial name
- NCT06074276
- Testing
- Food: whole almonds, Food: non-nut snack
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Acne, Wrinkle
Fractional Radiofrequency for Treatment of Acne Scars and Wrinkles
This study will evaluate the clinical efficacy, safety and the performance of the fractional radiofrequency delivered by the BTL-585-4 applicator of the BTL-585F system for non-invasive treatment of acne scars and facial…
- Trial name
- NCT05827510
- Testing
- BTL-585F
- Where
- 2 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Skin Aging, Cheek Wrinkles
TCRM for Correction of Cheek Including Fine Lines
The purpose of this clinical study is to evaluate benefits and risks of injecting TCRM in the cheek including fine lines. The goal is to show that treatment with TCRM will result in correcting the cheek area including the fine…
- Trial name
- NCT07145905
- Testing
- TCRM
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Peri-orbital Wrinkles, Peri-oral Wrinkles
Peri-orbital and Peri-oral Wrinkle Reduction Trial
This is prospective, multi-center, single-blinded, non-randomized clinical trial. Enrolled subjects will receive two Ulthera® treatments on the peri-orbital and peri-oral regions, each treatment provided 30 days apart.
- Trial name
- NCT01981252
- Testing
- Ulthera® System Treatment
- Where
- 5 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Lateral Canthal Lines, Crow's Feet
Dose Finding Study In Subjects With Crow's Feet
The purpose of this study is to establish the therapeutic range of ANT-1401 in the treatment of Crow's Feet.
- Trial name
- NCT01951742
- Testing
- ANT-1401, Vehicle
- Where
- 10 sites in United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Anterios Inc.
Chronic Effect of Ultraviolet Radiation on Photoaged Skin, Dermatologic Disorders
Safety Study of Bone Marrow Derived Stem Cells on Patients With Cutaneous Photoaging
The purpose of this study is to determine whether a one-time injection of allogeneic mesenchymal bone marrow cells is safe and beneficial in the treatment of photodamage on the face.
- Trial name
- NCT01771679
- Testing
- Allogeneic Mesenchymal Bone Marrow Cells
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Stemedica Cell Technologies, Inc.
Facial and Neck Rhytides
Prospective Pellevé™ Neck Wrinkle Study
Use of RF device to treat wrinkles of the neck
- Trial name
- NCT01299090
- Testing
- Pelleve Wrinkle Treatment System - includes the Pelleve Handpiece and S5 generator
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Ellman International
Wrinkle, Rhytides
Healing Study of Fractional Skin Resurfacing and Tissue Histopathology After Ellacor Treatment
The goal of this study is to observe the healing of skin after ellacor® treatment at different timepoints, depths and coring densities.
- Conditions
- Wrinkle, Rhytides, Histopathology
- Trial name
- NCT06502470
- Testing
- ellacor® Micro-Coring procedure
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Cytrellis Biosystems, Inc.