Clinical trials: Wrinkle Reduction
Wrinkled Structure, Circumference Reduction
Evaluation of Safety and Efficacy of Using Venus Freeze™ (MP)2 V2 System for Wrinkles Rhytides and Cellulite Treatment
Skin aging is a multifactorial process involving the 3 layers of the skin: Epidermis, dermis and hypodermis. Radio-frequency (RF) devices have been used for many years for a variety of surgical applications.
- Trial name
- NCT01234259
- Testing
- Venus Freeze (MP2 V2 System
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Periorbital Wrinkles
Reducing Wrinkles Around the Eyes Using the Ulthera® System
The purpose of this prospective, multi-center, single treatment study is to evaluate the clinical outcomes associated with the non-invasive treatment to reduce wrinkles around the eyes utilizing the Ulthera® System to deliver…
- Trial name
- NCT01368900
- Testing
- Ulthera® System treatment
- Where
- 2 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc
Skin Tightening, Skin Laxity
Efficacy of Long Pulsed 1064nm Laser for Facial Skin Tightening
We study the efficacy of 1 pass of stacking pulses of long pulse 1064nm laser on the face for skin tightening immediately post laser and 3 months follow up.
- Conditions
- Skin Tightening, Skin Laxity, Wrinkle Reduction
- Trial name
- NCT01971736
- Where
- Thailand
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Phramongkutklao College of Medicine and Hospital
Aging Problems, Wrinkle
Comparing Polydioxanone Thread Embedding Acupuncture and Manual Acupuncture for Nasolabial Fold Reduction
This study was aimed to compare the effectiveness of polydioxanone thread embedding acupuncture and manual acupuncture on the reduction of the nasolabial fold.
- Trial name
- NCT05098912
- Testing
- Manual acupuncture, Thread embedding acupuncture
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Skin Care
Investigating the Wrinkle Reduction Potential of a Novel Compounded Skin Care Cream
In the realm of cosmetics, skin care accounts for a significant share accounting for 35.3% of the global market, creating a $121 billion industry.
- Trial name
- NCT03878381
- Testing
- Skin Care Cream
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Wrinkle Reduction
Pivotal Study of the Cutera truSculpt Radiofrequency Device for Wrinkle Reduction
The purpose of this pivotal investigation is to evaluate the safety and efficacy of the Cutera truSculpt™ radiofrequency (RF) Device for Wrinkle Reduction.
- Trial name
- NCT03285581
- Testing
- truSculpt RF
- Where
- 2 sites in United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Healthy Adult Females
Clinical Study to Evaluate the Anti-aging Efficacy and Skin Radiance-enhancing Effect of Dermial®.
The present clinical study has been designed to evaluate the efficacy and safety of Dermial® at a daily dose of 60 mg on skin brightness, hydration, luminosity and other signs of facial skin aging in healthy women aged 35 to 65…
- Trial name
- Dermiglow (NCT07790237)
- Testing
- DERMIAL
- Where
- Spain
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Bioiberica
Wrinkle
BTL-785F Device for Non-invasive Reduction of Wrinkles
This study will evaluate the clinical safety and the performance of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive treatment of facial wrinkles.
- Trial name
- NCT05519124
- Testing
- BTL-785-7
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Hair Reduction, Tattoo Removal
Clinical Study to Evaluate the Safety and Efficacy of Candela Technology
This is a non-randomized, multi-center, open-label, prospective clinical study evaluating the clinical treatment with Candela Medical Technology.
- Conditions
- Hair Reduction, Tattoo Removal, Wrinkle, Acne
- Trial name
- NCT06202274
- Testing
- Nordlys, Gentle, Picoway, Vbeam, Profound, Profound Matrix, eTwo, Exceed, CO2RE
- Where
- 3 sites in United States, Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Skin Wrinkles
Study on the Safety, Efficacy of Home RF Cosmetic Instrument in the Treatment of Facial or Periorbital Wrinkles
This is a multicenter trial with randomized control and evaluator blind method, which meets the screening criteria total of 224 subjects were enrolled and randomly divided into control group and experiment according to 1:1 ratio…
- Trial name
- YM-1 (NCT06441799)
- Testing
- Home radiofrequency skin treatment instrument, Ultrasonic coupler for medical purposes
- Where
- China
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Glomed(HN)Co.Ltd
Facial Photoaging, Deepening of Facial Wrinkles
Regenmedic Cream 2.0 12-week Long-term Clinical Test
The goal of this study is to evaluate the anti-wrinkle, firming, moisturizing and repairing efficacy of a test facial cream after single use and 12 weeks of continuous use via clinical evaluation, instrumental measurement, image…
- Conditions
- Facial Photoaging, Deepening of Facial Wrinkles, Skin Laxity, Decreased Skin Elasticity
- Trial name
- NCT07874113
- Testing
- Test facial cream (topical skin care product)
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Skin Wrinkling
Bausch Health Thermage FXL for Use on Lower Face and Submentum Area
This study is designed to evaluate the safety and efficacy of sequential use of monopolar radiofrequency on lower face and submental area, followed by cryolipolysis on the submentum and submandibular area for fat reduction and…
- Trial name
- NCT04606368
- Testing
- Thermage FLX
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Lorraine Hickson
Facial Wrinkles and Rhytides Reduction
Cream Short-term Efficacy Clinical Study
This study aimed to evaluate the short-term efficacy of a facial cream (Formula# 899675 44A) on improving various skin quality and wrinkle parameters after a single application.
- Trial name
- NCT07067086
- Testing
- Test Cream
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Wrinkle
BTL-785F Device for Non-invasive Reduction of Wrinkles and Overall Facial Improvement
This study will evaluate the clinical safety and the performance of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive treatment of facial wrinkles.
- Trial name
- NCT05524779
- Testing
- BTL-785-7
- Where
- 5 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Facial Aging, Skin Rejuvenation
Performance and Safety of Semical Dermal Fillers in Facial Rejuvenation
The aim of the study is to verify safety and performance of Semical dermal fillers according to real-world data.
- Conditions
- Facial Aging, Skin Rejuvenation, Volume Defects in the Mid-face, Lip Augmentation and Correction of Perioral Rhytids
- Trial name
- SEMDERMA (NCT07160777)
- Testing
- cross-linked hyaluronic acid, Mesolifter
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Semikal Technology
Wrinkles, Fine Lines
Clinical Study to Assess Safety, Effectiveness and In-Use Tolerability of Saffron Extract Capsules for Improving Skin Health and Reducing Signs of Aging on Healthy Adult Male and Female Subjects.
This is a randomized, double-blind, comparative, two-arm, prospective, interventional, multi-centre clinical study to evaluate the safety, efficacy, and in-use tolerability of test products, standardized saffron extract capsules…
- Conditions
- Wrinkles, Fine Lines, Hyperpigmentation, Dark Spots
- Trial name
- GLOW (NCT07324759)
- Testing
- Standardized Saffron Extract (Crocus Sativus L) 10 mg Capsule
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Wrinkle
Evaluation of Safety and Efficacy of the BTL-785F Device for Non-invasive Reduction of Wrinkles
This study will evaluate the clinical safety and the performance of the BTL-785F system equipped with BTL-785-2 applicator for non-invasive treatment of facial wrinkles.
- Trial name
- NCT04447963
- Testing
- Non-invasive treatment of facial wrinkles
- Where
- Bulgaria
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Wrinkle Reduction
A Prospective Pilot Study to Evaluate Safety and Effectiveness of GP0122 and GP0124 for Correction of Lines and Wrinkles in the Cheek Area
The primary objective of the study is to evaluate the safety of GP0122 and GP0124 for the correction of lines and wrinkles in the cheek area.
- Trial name
- NCT07344584
- Testing
- GP0122, GP0124
- Where
- 5 sites in Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Rhytides, Wrinkle
Clinical Evaluation of Fractional Radiofrequency for the Treatment and Reduction of Facial Wrinkles
Prospective, single centre, evaluator-blind study of the safety and performance of fractional radiofrequency (RF) for the treatment and reduction of facial wrinkles.
- Trial name
- NCT03831477
- Testing
- Venus Viva
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Peri-orbital Wrinkles, Peri-oral Wrinkles
Peri-orbital and Peri-oral Wrinkle Reduction Trial
This is prospective, multi-center, single-blinded, non-randomized clinical trial. Enrolled subjects will receive two Ulthera® treatments on the peri-orbital and peri-oral regions, each treatment provided 30 days apart.
- Trial name
- NCT01981252
- Testing
- Ulthera® System Treatment
- Where
- 5 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ulthera, Inc