Clinical trials: Wrinkles and Rhytides
Wrinkles
Silk'n HST Device Usability and Self Selection Study
This is a Usability study, conducted for the purpose of testing Silk'n HST Device usability.
- Trial name
- NCT02919007
- Testing
- Silk'n HST treatment
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Home Skinovations Ltd.
Wrinkle, Photoaging
An Exploratory Investigation of a Novel Skincare Regimen
This trial will assess the effectiveness of the Aria Trio Complete Facial system in being able to reduce blemishes, lines, and wrinkles.
- Conditions
- Wrinkle, Photoaging, Acne, Skin Inflammation
- Trial name
- NCT05517720
- Testing
- Aria Trio complete Facial System
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Trophy Skin
Nasolabial Folds
An Efficacy and Safety Study of TheraFill® Versus KOKEN for 3 Months on Nasolabial Folds
Investigational Device : TheraFill® (Atelocollagen Dermal Filler) Title : A Randomized, Multicenter, Prospective and Paired Comparison of the Efficacy and Safety of TheraFill® versus KOKEN for 3months on Nasolabial Folds Sites…
- Trial name
- NCT01060943
- Testing
- KOKEN, Atelocollagen Filler
- Where
- South Korea
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Cellontech Co., Ltd.
Lateral Canthal Lines, Crow's Feet
A 4-Arm Efficacy and Safety Study of RT001 for the Treatment of Moderate to Severe Lateral Canthal Lines in Adults
The purpose of this study is to find out if an investigational drug, called RT001 Topical Gel, is safe and useful in minimizing the wrinkles between the eye and hairline called lateral canthal lines, also known as crow's feet…
- Conditions
- Lateral Canthal Lines, Crow's Feet, Facial Wrinkles
- Trial name
- NCT01124552
- Testing
- RT001 Botulinum toxin type A (Dose A), RT001 Botulinum Toxin Type A (Dose B), Vehicle
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Revance Therapeutics, Inc.
Rhytides, Skin Texture Irregularities
Efficacy & Safety of hADM Skin Booster
The goal of this randomized, split-face, double-blinded clinical trial is to evaluate the efficacy and safety of Elravie Re2O (particulated human Acellular Dermal Matrix, phADM) as a skin booster compared with hyaluronic acid…
- Conditions
- Rhytides, Skin Texture Irregularities, Photoaged Facial Skin, Skin Lifting and Tightening
- Trial name
- NCT07155278
- Testing
- Elravie Re2O, Elravie Balance
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
Skin Wrinkles on Face and Neck Areas
Study to Determine Effectiveness of Activation Mist on Facial Skin Wrinkles
To determine the effect of Activation Mist (AM) on skin wrinkles and appearance.
- Trial name
- NCT01939964
- Testing
- Activation Mist
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- California Allergy and Asthma Medical Group, Inc.
Hyaluronic Acid, Dermal Fillers
Clinical Trial of Cross-linked Hyaluronic Acid Dermal Filler
The goal of this clinical trial is to evaluate the safety and efficacy of Formaderm Young Dermal Filler Injection, which is a hyaluronic acid dermal filler injected into the mid to deep dermis for the correction of…
- Trial name
- NCT05935501
- Testing
- Formaderm Young, Restylane
- Where
- 2 sites in China
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Maxigen Biotech Inc.
Face; Atrophy
DA-13-007 Versus Sculptra for the Treatment of Nasolabial Folds Wrinkles
Study DA-13-007 is a randomized, evaluator-blinded, within subject (split face) multicenter clinical study of DA-13-007l (Injectable poly-l-lactic acid) compared to SCULPTRA in the treatment of nasolabial fold wrinkles.
- Trial name
- NCT02310490
- Testing
- DA-13-007 right with left side Sculptra left side, DA-13-007 left with left side Sculptra right side
- Where
- 4 sites in United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- DermAvance
Face Rejuvenation, Neck Rejuvenation
Laser Treatment for Facial and Neck Rejuvenation
To assess the efficacy, safety, and patient satisfaction associated with the treatment of the face and neck with the 2,910nm mid-infrared UltraClear Laser System using both superficial epidermal ablation and deep ablative and…
- Trial name
- NCT05808842
- Testing
- CeraVe, CeraVe and Calecim
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Wrinkles and Rhytides
Eye Cream 8-Week Efficacy Clinical Study
To investigate efficacy on test cream [Formula#899675 44A] on female subjects after 2-week wash-out and 8-week repeated application.
- Trial name
- NCT07079501
- Testing
- Test Eye Cream (Formula# 899675 44A)
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Wrinkle, Pigment Skin
A Clinical Study to Assess the Safety and Effectiveness of Anti-Ageing and Skin Brightening Gel
This is a Randomized, Interventional, Prospective, Double Blind, Two Arm, Comparative, Parallel, Placebo-Controlled, Safety and Efficacy Study of Anti-Ageing and Skin Brightening Gel.
- Conditions
- Wrinkle, Pigment Skin, Aging
- Trial name
- NCT06123572
- Testing
- Anti-Ageing and Skin Brightening Gel
- Where
- India
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Wrinkles, Scars
Pilot Evaluation of the Cynosure Potenza™ System for Treatment of Cosmetic Dermatologic Skin Conditions
The primary objective of this pilot study is exploratory investigation evaluating the Potenza microneedle fractional radiofrequency (RF) device and may be used in combination with the Icon intense pulsed light (IPL) device.
- Conditions
- Wrinkles, Scars, Stretch Marks, Pigmentation
- Trial name
- NCT05847530
- Testing
- Potenza, Icon
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cynosure, Inc.
Wrinkle, Skin Laxity
Lutronic Genius System for Neck Treatment
The Genius system is substantially equivalent to the Infini device (K121481). The study is a prospective, multi-site, non-randomized study of up to 30 treated subjects presenting for treatment of mild to moderate lines, wrinkles…
- Conditions
- Wrinkle, Skin Laxity, Skin Texture Disorder
- Trial name
- NCT03534609
- Testing
- Lutronic Genius System
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- CynosureLutronic
Wrinkle
BTL-785F Device for Non-invasive Treatment of Wrinkles and Improvement of the Face Appearance
This study will evaluate the clinical safety and the performance of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive treatment of facial wrinkles.
- Trial name
- NCT05524805
- Testing
- BTL-785-7 Treatment
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Facial Aging, Skin Rejuvenation
Performance and Safety of Semical Dermal Fillers in Facial Rejuvenation
The aim of the study is to verify safety and performance of Semical dermal fillers according to real-world data.
- Conditions
- Facial Aging, Skin Rejuvenation, Volume Defects in the Mid-face, Lip Augmentation and Correction of Perioral Rhytids
- Trial name
- SEMDERMA (NCT07160777)
- Testing
- cross-linked hyaluronic acid, Mesolifter
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Semikal Technology
Facial Wrinkles
A Post-Market Study to Evaluate Adverse Event Incidence Rates in Patients With Skin of Color Undergoing Correction of Nasolabial Folds With Hylaform, Hylaform Plus and Captique.
To assess the likelihood of keloid and scar formation, pigmentation disorders and hypersensitivity reactions in patients with skin of color undergoing correction of facial soft tissue contour deficiencies with Hylaform, Hylaform…
- Trial name
- NCT00293163
- Testing
- Hylaform, Hylaform Plus (hylan B gel)
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- Genzyme, a Sanofi Company
Facial Wrinkles, Anti-Aging
Safety and Efficacy Evaluation of the Monopolar Radiofrequency Device for the Improvement of Facial Wrinkles
The goal of this clinical trial is to evaluate the safety and efficacy of the monopolar radiofrequency therapy device developed by CLASSYS Inc. for improving facial and periorbital wrinkles.
- Conditions
- Facial Wrinkles, Anti-Aging, Wrinkles and Rhytides, Wrinkles Such as Nasolabial Folds
- Trial name
- NCT06657365
- Testing
- Radiofrequency (RF) Treatment with Volnewmer, Radiofrequency (RF) Treatment with Thermage CPT
- Where
- China
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.
Dry Skin
Evaluation of Human Efficacy for Skin Moisturization and Wrinkle Improvement
All subjects used the placebo sample on the left side of their face and the investigational sample on the right side of their face, respectively.
- Trial name
- NCT05872113
- Testing
- Hs-hWE cream
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Ji Hye Yoon
Parotid Gland Tumor, Facial and Neck Rhytides
Facial Nerve Monitoring During Parotid and Facial Surgery Using a Non-Invasive Patch
The goal of this study is to test if a non-invasive patch can safely monitor facial nerve activity in adults during parotid or facial surgery.
- Trial name
- NCT07523373
- Testing
- Non-invasive facial nerve monitoring patch
- Volunteers
- 20 people
- Sponsor
- Sheba Medical Center
Skin Laxity, Wrinkle
Clinical Feasibility Study to Evaluate the Safety and Performance of the Profound Matrix System
This is a non-randomized, multi-center, open-label clinical trial evaluating clinical feasibility treatments with the Profound Matrix system.
- Conditions
- Skin Laxity, Wrinkle, Skin Condition
- Trial name
- NCT06157567
- Testing
- Profound Matrix
- Where
- 6 sites in United States, Canada and 1 more
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Candela Corporation