Clinical trials: Wrinkles and Rhytides
Periorbital Wrinkles, Periorbital Area
Non-invasive Rejuvenation of the Periorbital Area and Lower Eyelid
The goal of this clinical trial is to determine the BTL-785-7-11 applicator effectiveness for an under-eye appearance improvement by evaluation of the periorbital area in healthy adult volunteers.
- Conditions
- Periorbital Wrinkles, Periorbital Area, Under-eyes Dark Circles, Crows Feet
- Trial name
- NCT07028203
- Testing
- Treatment with BTL-785 with the applicator BTL-785-7-11
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Wrinkles and Rhytides
Treatment of Aging Signs of the Skin With Bipolar Radiofrequency
This is a retrospective data collection from patients treated with the bipolar radiofrequency applicator (Coaxipolar) of the Accent devices.
- Trial name
- NCT07739212
- Where
- Kosovo
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Alma Mater Europaea College of Medical Sciences "Rezonanca"
Fine Lines and Wrinkles, Skin Health
Efficacy of an LED Mask
The goal of this interventional study is to evaluate the efficacy and perception a commercial LED device in 110 healthy adult females and males between the ages of 35-65 years old, inclusively.
- Conditions
- Fine Lines and Wrinkles, Skin Health, Skin Tone
- Trial name
- NCT07890233
- Testing
- Light emitting diode treatment
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Therabody, Inc.
Rhytides
The Effect of Almonds on Skin Lipids and Wrinkles
Investigators hypothesize that regular consumption of almonds will augment the long chain fatty acid profile and the alpha-tocopherol levels, improve the skin barrier function, and improve the appearance of facial wrinkles in…
- Trial name
- NCT02954315
- Testing
- Almonds
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Wrinkle
Assess Impact of Microdroplet Hyaluronic Acid Filler on Skin Quality in Patients on Glucagon-like Peptide-1 Agonists
Clinical trial to assess the effect of microdroplet hyaluronic acid filler to the cheek skin (SKINVIVE™, JUVÉDERM®, Irvine, CA) on skin quality in patients undergoing medical weight loss with GLP-1 therapy.
- Trial name
- NCT07221461
- Testing
- Skinvive
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Goldman, Butterwick, Fitzpatrick and Groff
Healthy Adult Females
Clinical Study to Evaluate the Anti-aging Efficacy and Skin Radiance-enhancing Effect of Dermial®.
The present clinical study has been designed to evaluate the efficacy and safety of Dermial® at a daily dose of 60 mg on skin brightness, hydration, luminosity and other signs of facial skin aging in healthy women aged 35 to 65…
- Trial name
- Dermiglow (NCT07790237)
- Testing
- DERMIAL
- Where
- Spain
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Bioiberica
Wrinkle, Fine Lines
Feasibility Study to Collect and Assess Safety Data for a Radiofrequency Microneedling Device for Electrocoagulation and Hemostasis of Soft Tissues for Dermatologic Conditions
The goal of the Potenza device used in this study is to collect clinical data for dermatologic conditions in which electrocoagulation and hemostasis is a viable mechanism for means of improvement.
- Conditions
- Wrinkle, Fine Lines, Crepey Skin, Acne Scars
- Trial name
- NCT05987319
- Testing
- RadioFrequency Microneedling Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cynosure, Inc.
Aging, Pain
Safety and Efficacy of the Addition of 0.3% Lidocaine With EVOLENCE®
The study doctor will give EVOLENCE® mixed with Lidocaine to people in this study to see if it effectively reduces pain while injecting and works to correct nasolabial wrinkles.
- Trial name
- AD-1016 (NCT00929071)
- Testing
- Evolence, Lidocaine, topical anesthetic
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Weinkle, Susan H., M.D.
Aesthetics Procedure
Post-market Study on BtHCROSS® for Restoring Facial Volume After a Single Injection
This clinical study investigated the safety and effectiveness of BtHCROSS, a hyaluronic acid-based injectable used to restore facial volume and reduce wrinkles.
- Trial name
- NCT07301619
- Testing
- BtHCROSS®
- Where
- Spain
- Volunteers
- 203 people
- Sponsor
- i+Med S.Coop.
Skin Aging, Skin Wrinkling
Evaluation of the Safety and Performance Characteristics of Mesofiller Mesotox for the Correction of Wrinkles and Rehydration of the Face.
The investigation is a single-centre, interventional, prospective, non-randomized, open-label, uncontrolled, single-arm, un-blinded investigation for the evaluation of the safety and performance of the product mesofiller® mesotox…
- Trial name
- NCT06477432
- Testing
- mesofiller® mesotox
- Where
- Bulgaria
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Mesoestetic Pharma Group S.L.
Wrinkle Test
Inter-observer and Intra-observer Variability of the Wrinkle Test
Skin wrinkling of the fingers following immersion in warm water depends on intact sympathetic innervation. It is abolished by lesions affecting both central and peripheral sympathetic pathways.
- Trial name
- NCT03813758
- Testing
- wrinkle test
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Dermal Fillers, Cheek Augmentation
Evaluation of Performance and Safety of Injectable KIO017 Device Range for Facial Tissue Filling
The goal of this clinical trial is to primarily evaluate the performance of KIO017 in filling/volumizing after injection in different areas in healthy women or men, older than 18 years and seeking an improvement of her/his face…
- Conditions
- Dermal Fillers, Cheek Augmentation, Lip Augmentation, Perioral Rhytids
- Trial name
- LITCHEE (NCT06872359)
- Testing
- KIO017-1, KIO017-2, KIO017-3
- Where
- 3 sites in France, Poland
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Kiomed Pharma
Wrinkle
A Prospective, Single Center, Single-Arm Clinical Study of 20 Participants to Reduce the Appearance of the Peri-orbital Wrinkles. Participants Will Receive up to Four Treatments With Tixel Every 4 Weeks. Follow-up Will Occur 1 Month and 3 Months Following Last Treatment.
A Prospective, Single center, Single-Arm Clinical Study of 13-20 study participants who are seeking a procedure to reduce the appearance of the peri-orbital wrinkles.
- Trial name
- NCT05282979
- Testing
- Tixel 2
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Physicians Laser and Dermatology Institute
Facial Wrinkles, Jawline Contour
Evaluation of SofWave Sofware-Guided Energy Delivery for Lower Face and Neck Rejuvenation
Non-randomized single-arm prospective clinical study.
- Conditions
- Facial Wrinkles, Jawline Contour, Skin Laxity
- Trial name
- NCT07723664
- Testing
- SofWave
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD
Photoaging, Wrinkle
Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional Ablative CO2 Laser for Facial Rejuvenation
This randomized, single-center, double-blinded, split-face, controlled clinical trial was conducted to investigate the tolerability, safety, and efficacy of a post-procedure cream when used immediately after fractional ablative…
- Conditions
- Photoaging, Wrinkle, Skin Laxity
- Trial name
- NCT06366503
- Testing
- Fractional Ablative CO2 Laser, Facial Cleanser, Facial Moisturizer
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Skin, Skin Manifestations
Placebo Controlled Efficacy Evaluation of the Hydrolyzed Collagen Peptide In Adult Females
The aim of this study is to evaluate the contribution of hydrolized collagen products to elasticity, hydration and roughness of the skin of female volunteers.
- Conditions
- Skin, Skin Manifestations, Wrinkle
- Trial name
- NCT05235997
- Testing
- Hydrolized Collagen Peptide
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sel Sanayi Urunleri Ticaret ve Pazarlama A.S.
Aging
Safety and Efficacy of the EndyMed Pro System Using RF Micro-needles Fractional Skin Remodeling
The need for cosmetic facial enhancement procedures with minimal down time and low risk has led to the development of methods for non-surgical skin rejuvenation.
- Trial name
- NCT02368626
- Testing
- EndyMed Pro™ RF Micro-Needles
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- EndyMed
Wrinkle
The Effects of a 3-Part Skin Care Regimen on Facial Wrinkles and Biophysical Attributes
The purpose of this study is to analyze various cosmetic endpoints, subjective assessments, and skin parameters such as hydration, transepidermal water loss, fine lines, and wrinkles with the use of a 3-part skin care regimen.
- Trial name
- NCT05698485
- Testing
- Cleansing Balm, Facial Serum, Moisturizer
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Wrinkles
Clinical Trial to Evaluate Safety and Efficacy of Ultherapy™ System for Lifting Skin on the Neck
Study is a prospective clinical trial to evaluate the efficacy of the Ulthera® System to improve Lifting Skin on the Neck. Changes from baseline in the FACE-Q Appraisal of Neck scale score and Global Aesthetic Improvement Scale…
- Trial name
- NCT02368925
- Testing
- Ultherapy™ System
- Where
- South Korea
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Skin Aging, Facial Wrinkles
Study of the Subdermal Implant "Algeness"
A single-center clinical study of the efficacy and safety of the medical device "Algeness subdermal implant based on agarose (Ghimas SpA/Ghimas SpA, Italy) in the correction of skin contour defects.
- Conditions
- Skin Aging, Facial Wrinkles, Soft Tissue Volume Loss, Lipoatrophy
- Trial name
- NCT07618468
- Testing
- Algeness Subdermal Implant (Agarose)
- Where
- Russia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Estelab Clinic