Clinical trials: Xenograft
Horizontal Alveolar Bone Loss
Alveolar Ridge Augmentation With Curcumin Combined With Xenograft
A study was performed to investigate the effect of curcumin on the osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs) and its underlying potential mechanism.
- Trial name
- NCT04971382
- Testing
- Curcumin
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Ain Shams University
Tooth Loss
Comparison of Dimensional Changes After Tooth Extractions Between Xenograft and Allograft
To compare dimensional changes in extraction socket of single rooted teeth, 6 months post extraction, when grafted with xenograft versus allograft.
- Trial name
- PilotXenAllo (NCT04550689)
- Testing
- Bone graft
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- UConn Health
Ridge Preservation
Ridge Preservation Using Collagen Sponge Alone or Combined with Xenograft: a Clinical and Histological Trial
24 patients had a treatment plan for extraction of non restorable single rooted maxillary tooth and will be subjected to one of three groups after tooth extraction Group (I): including 8 patients, preservation of extraction…
- Trial name
- NCT06896097
- Testing
- Ridge preservation
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Periodontitis, Periodontal Bone Loss
Non-incised Papillae Surgical Approach (NIPSA) and Connective Tissue Graft Plus Emdogain for Periodontal Defects
The present study pretends to show the results of combining a modification of the Non-incised papillae surgical approach (NIPSA) attempting to improve the outcome in the treatment of teeth with advanced periodontal support loss.
- Conditions
- Periodontitis, Periodontal Bone Loss, Periodontal; Lesion
- Trial name
- NCT03997578
- Testing
- NIPSA (Non-incised papilla surgical approach), NIPSA plus connective tissue graft
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Murcia
Alveolar Bone Loss, Socket Shield Technique
Socket Shield Technique With CGF and Xenograft for Immediate Implants
This prospective case series aims to evaluate the clinical and radiographic outcomes of immediate implant placement using the socket shield technique combined with concentrated growth factors (CGF) and xenograft in the esthetic…
- Conditions
- Alveolar Bone Loss, Socket Shield Technique, Bone Resorption, Immediate Dental Implant Placement
- Trial name
- CGF (NCT07520513)
- Testing
- Socket Shield Technique with Immediate Implant Placement and CGF + Xenograft
- Where
- Egypt
- Volunteers
- 7 people
- Sponsor
- Cairo University
Rotator Cuff Tears
Rotator Cuff Augmentation With Human Dermal Allograft Versus Bovine Collagen Xenograft Patch: A Randomized Controlled Trial
Randomized controlled trial comparing human dermal allograft with bovine collagen xenograft in rotator cuff repair.
- Trial name
- HDA v Regen (NCT06215417)
- Testing
- Rotator cuff repair
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Alveolar Bone Resorption
Comparison of Autogenous Dentin Matrix Versus Bovine-Derived Xenograft for Socket Preservation
The present study is a human, prospective, randomised controlled clinical trial will be conducted to explore and compare the clinical, radiographic and histomorphometric outcome of autogenous demineralised dentin(DDM) versus…
- Trial name
- NCT04239378
- Testing
- socket preservation
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Burns Scald
Silver Foam Dressing Superior to Porcine Xenograft in Pediatric Scalds
Prospective randomized trial where two dressings has been compared for partial thickness scald burns in children 6 months to 6 years.
- Trial name
- NCT04410497
- Testing
- Porcine xenograft (wound dressings), Silver foam (wound dressings)
- Where
- Sweden
- Volunteers
- 58 people
- Sponsor
- University Hospital, Linkoeping
Bone Loss
Evaluation of Marginal Bone Loss After Immediate Implant Placement in Esthetic Zone Without Xenograft.
Marginal bone loss in immediate implant placement in upper esthetic zone by comparing between non grafting in immediate implant placement with xenograft placement in other side.
- Trial name
- NCT03397316
- Testing
- xenograft placement .
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cairo University
Implant Dentistry
Efficacy of Xenograft Alone or Mixed With Arginyl-Glycyl-Aspartic Acid (RGD) in Horizontal Ridge Augmentation With Split-crest Technique for Implant Placement
The aim of the present study is to evaluate the efficacy of xenograft alone or xenograft mixed with Arginylglycylaspartic acid (RGD) , in horizontal ridge augmentation with split-crest technique, for implant placement.
- Trial name
- NCT06585852
- Testing
- RGD, Xenograft, Split crest technique
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Collecting and Storing Tissue From Young Patients With Cancer
This laboratory study is collecting and storing tissue, blood, and bone marrow samples from young patients with cancer. Collecting and storing samples of tissue, blood, and bone marrow from patients with cancer to study in the…
- Conditions
- Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Central Nervous System Neoplasm, Ewing Sarcoma
- Trial name
- NCT00898755
- Testing
- Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis
- Where
- 68 sites in United States, Canada
- Volunteers
- 213 people
- Sponsor
- Children's Oncology Group
Implant Site Reaction
Immediate Implant Placement With Immediate Professionalization in Aesthetic Area
Immediate implant placement with immediate professionalization in the maxillary esthetic zone using mixture of allograft and xenograft vs xenografts to augment the jumping gap
- Trial name
- NCT03665025
- Testing
- immediate implant using mixed allograft and xenograft
- Where
- Kuwait
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteosarcoma
Patient-derived Xenograft (PDX) Modeling to Test Drug Response for High-grade Osteosarcoma
By obtaining clinical specimens from participants with high-grade bone and soft tissue sarcomas to establish and profile as freshly implanted tumors in mice, the aim of this study is to identify agents with predicted activity in…
- Trial name
- NCT03358628
- Testing
- Molecular Profiling & In Vivo drug testing in PDX
- Volunteers
- 20 people
- Sponsor
- Peking University People's Hospital
Crestal Bone Loss
Soft Tissue Esthetic With Autogenous Dentin Chips and Immediate Implantation Versus Conventional Immediate Implantation With Xenograft in Thin Buccal Bone
After tooth extraction, host bone resorption and atrophy of alveolar ridge may be observed. Bone resorption occurs specially in incisors and premolar area of jaw in region of thin buccal bone that may lead to change in contour.
- Trial name
- NCT03544580
- Testing
- immediate implant with dentine chips, conventional immediate implant
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Edentulous Alveolar Ridge
Implant Placement in Mandibular Molar Xenograft Versus PRF
20 recruited patients indicated for immediate implant placement in mandibular molar patients are divided into 2 groups each group contain 15 patients, one group assigned for placement of bovine bone after molar extraction and…
- Trial name
- NCT03177356
- Testing
- extraction,implant placement,PRF, Exctraction,Implant placement,Bone graft
- Volunteers
- 20 people
- Sponsor
- Cairo University
Corneal Transplantation
Prospective Study of Deep Anterior Lamellar Keratoplasty Using Acellular Porcine Cornea
The performance of keratoplasty is hampered by the limited availability of donor cornea in many countries, especially in Asia. For this reason, attempts have been made to fabricate artificial substitutes for natural human cornea.
- Trial name
- NCT03105466
- Testing
- Deep anterior lamellar keratoplasty, Acellular Porcine Cornea, Tacrolimus eye drops
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Alveolar Ridge Deficiency
Horizontal Ridge Augmentation With Demineralized Bone Allograft Layered With Xenograft - a Prospective Clinical Study
The aim of this case series is to evaluate the outcomes of horizontal ridge augmentation performed using a combination of demineralized freeze-dried bone allograft layered with xenograft bone with a resorbable native collagen…
- Trial name
- NCT06342973
- Testing
- Xenograft and allograft
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Immediate Implant Placement
Effect of Albumin Platelet-Rich Fibrin or Leucocyte- Platelet-Rich Fibrin on Immediate Implant
The objective of this study will be to compare between Immediate Implant grafted with xenograft and Alb-PRF gel versus xenograft with L-PRF.
- Trial name
- NCT06863051
- Testing
- Immediate Implant Placement and Alb-PRF, Immediate Implant Placement and L-PRF
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Breast Cancer Female
Xenografts Development From Surgical Tumor Samples of Patients With Triple Negative or Luminal B Breast Cancer
Patient derived xenografts (PDX) from mammary tumors are usually made from metastatic tumors. Indeed, PDX from primitive mammary tumors or after neoadjuvant treatment are still rare.
- Trial name
- XenoBreast (NCT04133077)
- Testing
- blood samples collection
- Where
- France
- Volunteers
- 85 people
- Sponsor
- Centre Jean Perrin
End Stage Renal Disease
Study of ChoironeX GalKO Porcine Thymokidney Xenotransplantation in End-Stage Renal Disease
The goal of this clinical trial is to learn if a GalKO Porcine Thymokidney can maintain renal function, without the need for dialysis, after transplantation into adult subjects with End Stage Renal Disease.
- Trial name
- NCT07696962
- Testing
- ChoironeX GalKO Porcine Thymokidney
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Xeno Holdings (US), LLC dba ChoironeX