Clinical trials: Xenograft
Alveolar Bone Loss
Lamina Soft With Different Collagen Based Materials in Bone Regeneration
This prospective controlled clinical pilot study will compare the effectiveness of two different grafting strategies for horizontal bone regeneration in healed post-extraction sites with buccal bone deficiency, using a…
- Trial name
- NCT07572643
- Testing
- Guided Bone Regeneration with Implant Placement, Collagenated Xenogeneic Bone Graft, Hydroxyapatite Xenograft with Autologous Bone
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Nicola Alberto Valente, DDS, MS, PhD
Urothelial Carcinoma
EGCG Modulate the Cytotoxic Effects of Chemotherapeutic Agents in Human Urothelial Carcinoma Cells
Urothelial carcinoma (UC) is the most common cancer of urinary tract. Patients with metastatic UC are usually treated with systemic chemotherapy.
- Trial name
- NCT01993966
- Where
- 2 sites in Taiwan
- Volunteers
- 25 people
- Sponsor
- National Taiwan University Hospital
Periodontitis, Intrabony Periodontal Defect
Treatment of Intrabony Defects With Injectable Platelet-Rich Fibrin and Xenogenic Grafts
The use of injectable platelet-rich fibrin (i-PRF) in both surgical and non-surgical dental treatments has become increasingly widespread.
- Conditions
- Periodontitis, Intrabony Periodontal Defect, Periodontal Diseases, Periodontal Defect
- Trial name
- NCT07146776
- Testing
- open flap debridement with I-prf and xenogeneic graft, open flap debridement with saline and xenogenic graft
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Alveolar Bone Loss
Comparison of Post Tooth Extraction Healing Using Different Xenograft Materials
The purpose of this pilot study is to conduct a interventional prospective clinical trial to evaluate the efficacy of three different xenografts for ridge preservation by comparing the quality of newly formed bone using…
- Trial name
- NCT03149172
- Testing
- Equimatrix®, Bio-Oss®, Endobon®
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Tufts University
Atrophic Maxilla
Assessment of Bone Quality and Quantity for Three Dimensional Bone Augmentation for Maxilla Using Patient Specific Titanium Meshes Loaded With Bone Marrow Aspirate Mixed With Xenograft Versus Xenograft Mixed With Autografts Only: a Randomized Clinical Trial
Assessment of bone quality and quantity for three dimensional bone augmentation for maxilla using titanium meshes loaded with bone marrow aspirate mixed with xenograft versus xenograft mixed with autografts only
- Trial name
- NCT05400044
- Testing
- Three dimensional maxillary bone augmentation
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Posterior Maxillary Atrophy, Maxillary Sinus Augmentation
Comparison of Allograft, Xenograft and Combined Grafting in Maxillary Sinus Augmentation
This prospective randomized clinical study evaluates and compares three different grafting approaches (allograft, xenograft, and combined grafting) used in lateral maxillary sinus augmentation prior to dental implant placement.
- Trial name
- SINUS-GRAFT (NCT07407361)
- Testing
- Lateral Maxillary Sinus Augmentation with Allograft, Lateral Maxillary Sinus Augmentation with Xenograft, Lateral Maxillary Sinus Augmentation with Combined Graft
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Tokat Gaziosmanpasa University
Burns
Pediatric Burn Treatment Using Tilapia Skin as a Xenograft for Superficial-Partial Thickness Wounds
This study aims to evaluate the efficacy of Nile tilapia skin as a xenograft for the treatment of partial-thickness burn wounds in children.
- Trial name
- NCT04391582
- Testing
- Tilapia skin, silver sulfadiazine cream 1%
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara
Parkinson's Disease
Investigation of the Safety and Efficacy of NTCELL® [Immunoprotected (Alginate-Encapsulated) Porcine Choroid Plexus Cells for Xenotransplantation] in Patients With Parkinson's Disease
To assess the safety of xenotransplantation of NTCELL [immunoprotected (alginate-encapsulated) choroid plexus cells] in patients with Parkinson's disease, assessed over the duration of the study, by monitoring the occurrence of…
- Trial name
- NCT02683629
- Testing
- NTCELL Implantation
- Where
- New Zealand
- Volunteers
- 18 people
- Sponsor
- Living Cell Technologies
Dental Implants
The Clinical Effect of Implant Placement With a Simultaneous Soft Tissue Allograft
Dental implant placement and simultaneous grafting using one layer gum graft will result in the same facial ridge contour and soft tissue thickness as one layer of gum graft plus bone graft.
- Trial name
- NCT02139748
- Testing
- Dental Implant & ADM, Dental Implant & ADM & bone xenograft
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Impacted Mandibular Third Molar Extraction, Dentin Graft
Autologous Dentine Graft Compared to Xenograft in Managing Periodontally Compromised Second Molar After Third Molar Removal
The goal of this study is to evaluate the efficacy of autologous dentin graft (ADG) in treating periodontal defects on the distal aspect of mandibular 2nd molar (M2) after surgical removal of impacted mandibular 3rd molar (M3) by…
- Conditions
- Impacted Mandibular Third Molar Extraction, Dentin Graft, Xenograft, Bone Defects
- Trial name
- NCT07362394
- Testing
- Autologous dentin graft, Xenograft
- Where
- Malaysia
- Volunteers
- 34 people
- Sponsor
- National University of Malaysia
Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies
Developing and Treating a Mouse Model of Acute Myeloid Leukemia Using Tissue Samples From Younger Patients With Acute Myeloid Leukemia
These laboratory trial studies the development and treatment of a mouse model for acute myeloid leukemia (AML) using samples from younger patients with AML.
- Trial name
- NCT01576185
- Testing
- laboratory biomarker analysis, quizartinib, sorafenib tosylate
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Children's Oncology Group
Crestal Bone Loss
Effect of Vitamin D on Crestal Bone Loss Around Immediate Implant After Mandibular Premolars and Molars Extraction
What is the difference between grafting the jumping gap upon using xenograft mixed with topical vitamin D clinically regarding crestal bone level and implant stability, radiographically regarding crestal bone level after implant…
- Trial name
- vitD (NCT07065877)
- Testing
- vit D mixed with xenograft, only xenograft without vit D
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Neuroendocrine Neoplasm
Single-cell Sequencing and Establishment of Models in Neuroendocrine Neoplasm
The aim of this study is to use single-cell sequencing technology to explore neuroendocrine neoplasm (NEN) molecular biological characteristics, tumor heterogeneity and cell subtypes. Besides.
- Trial name
- NCT04927611
- Testing
- Biopsy, open or laparoscopic surgery
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Fudan University
Autogenous Demineralized Dentin, Xenograft Bone Graft
Clinical and Radiographic Assessment of Socket Preservation Using Autogenous Demineralized Dentin Matrix Versus Xenograft
Total of 40 participants were planned for enrollment for socket preservation, 20 in the Autogenous Demineralized Dentin group and 20 in the Xenograft group these materials used for socket preservation after extraction.
- Trial name
- NCT07777588
- Testing
- Autogenous Demineralized Dentin, application of xenograft
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Multiligament Knee Injuries
OrthoPureXT Multiligament PMCF Study
To monitor residual risks in the post-market phase and to ensure continued clinical evaluation of the device safety and performance to ensure that no new or unexpected risks arise when used during multi-ligament knee…
- Trial name
- NCT05655156
- Testing
- OrthoPure XT
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Tissue Regenix Ltd
Edentulous Alveolar Ridge
Implant Placement in Mandibular Molar Xenograft Versus PRF
20 recruited patients indicated for immediate implant placement in mandibular molar patients are divided into 2 groups each group contain 15 patients, one group assigned for placement of bovine bone after molar extraction and…
- Trial name
- NCT03177356
- Testing
- extraction,implant placement,PRF, Exctraction,Implant placement,Bone graft
- Volunteers
- 20 people
- Sponsor
- Cairo University
Immediate Implant Placement in the Esthetic Zone, NON-RESTORABLE TOOTH IN ESTHETIC ZONE
Hyaluronic Acid Combined With Xenograft Versus Xenograft Alone in Immediate Implant Placement
This randomized controlled clinical trial aims to compare the clinical and radiographic outcomes of immediate implant placement using xenograft combined with hyaluronic acid versus xenograft alone in the esthetic zone.
- Trial name
- NCT07862686
- Testing
- Immediate implant placement, Xenograft, Hyaluronic Acid (0.2%)
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Cairo University
Alveolar Bone Resorption, Edentulous Alveolar Ridge
Ridge Preservation Using Xenogenic Bone Graft and Pre-hydrated Collagen Membrane
This pilot multicentric randomized controlled clinical trial is aimed at evaluating the composition of the new-formed tissue into the dental socket after 6 months from tooth extraction and the application of a combination of…
- Trial name
- NCT04955873
- Testing
- Treatment of the dental extraction socket using newly-released biomaterials, Treatment of the dental extraction socket using well-known biomaterials
- Where
- 5 sites in Italy
- Volunteers
- 45 people
- Sponsor
- Fondazione Bruno Kessler
Peri-implant Bone and Soft Tissues
Dimensional Changes of Peri-implant Tissues Following Jumping Gap Grafting Using Erythropoietin Gel Mixed With Xenograft.
This study will be conducted to compare the effect of Erythropoietin gel mixed with xenograft versus xenograft alone in grafting the jumping gap around immediate implant.
- Trial name
- NCT07523412
- Testing
- Erythropoetin gel mixed with xenogenic bone graft, Xenogenic bone with gelling aget CMC ( carboxymethyl cellulose)
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Ain Shams University
Xenograft Model
Xenograft and Posterior Mandibular Socket Filling
The aim of this study is to evaluate the volume of madibular bone after placement of a xenograft in a fresh extraction socket in human.
- Trial name
- Flapless (NCT02736773)
- Testing
- xenograft material to slow resorption
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Montpellier