Clinical trials: Xenograft
Alveolar Ridge Deficiency
Horizontal Ridge Augmentation With Demineralized Bone Allograft Layered With Xenograft - a Prospective Clinical Study
The aim of this case series is to evaluate the outcomes of horizontal ridge augmentation performed using a combination of demineralized freeze-dried bone allograft layered with xenograft bone with a resorbable native collagen…
- Trial name
- NCT06342973
- Testing
- Xenograft and allograft
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Jaw, Edentulous, Partially
Ridge Preservation Comparing the Healing With or Without a Barrier Membrane
Ridge Preservation Comparing the Clinical and Histologic Healing of Membrane vs. no Membrane Approach to Grafting.
- Trial name
- NCT02798887
- Testing
- Ridge preservation
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Parkinson's Disease
Investigation of the Safety and Efficacy of NTCELL® [Immunoprotected (Alginate-Encapsulated) Porcine Choroid Plexus Cells for Xenotransplantation] in Patients With Parkinson's Disease
To assess the safety of xenotransplantation of NTCELL [immunoprotected (alginate-encapsulated) choroid plexus cells] in patients with Parkinson's disease, assessed over the duration of the study, by monitoring the occurrence of…
- Trial name
- NCT02683629
- Testing
- NTCELL Implantation
- Where
- New Zealand
- Volunteers
- 18 people
- Sponsor
- Living Cell Technologies
Immediate Implant Placement
Effect of Albumin Platelet-Rich Fibrin or Leucocyte- Platelet-Rich Fibrin on Immediate Implant
The objective of this study will be to compare between Immediate Implant grafted with xenograft and Alb-PRF gel versus xenograft with L-PRF.
- Trial name
- NCT06863051
- Testing
- Immediate Implant Placement and Alb-PRF, Immediate Implant Placement and L-PRF
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Rotator Cuff Tears
Rotator Cuff Augmentation With Human Dermal Allograft Versus Bovine Collagen Xenograft Patch: A Randomized Controlled Trial
Randomized controlled trial comparing human dermal allograft with bovine collagen xenograft in rotator cuff repair.
- Trial name
- HDA v Regen (NCT06215417)
- Testing
- Rotator cuff repair
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Type 1 Diabetes
Safety and Efficacy Study of Islets Xenotransplantation
The neonatal pig islets will be used as donor culturing with our modified culture medium. At the same time the autologous T regulatory cells will be used to induce specific immune tolerance for porcine islets grafts combined the…
- Trial name
- NCT03162237
- Testing
- Porcine islets, Autologous Treg
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Wei Wang,MD
Guided Bone Regeneration
Assessment Of Guided Bone Regeneration Using Xenograft Mixed With Allogenic Bone Graft Versus Xenograft Mixed With Autogenous Graft For Augmentation Of Maxillary Alveolar Ridges
This study aims to evaluate the effect of Allogenic bone graft mixed with Xenograft in ratio 1:1, on the radiographic and histomorphometric assessment versus Autologous bone graft mixed with Xenograft in ratio 1:1 in maxillary…
- Trial name
- NCT07367464
- Testing
- Allogenic bone graft mixed with Xenograft in ratio 1:1, Autologous bone graft mixed with Xenograft in ratio 1:1
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontal Bone Loss
Erythropoietin Gel as an Adjunct to Xenograft in the Surgical Management of Intrabony Periodontal Defects
The aim of the study is to evaluate the use of erythropoietin gel as an adjunct to xenograft in the surgical management of intrabony periodontal defects.
- Trial name
- NCT05360511
- Testing
- particulate xenograft + erythropoietin gel., particulate xenograft
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Lichen Planus
Methods Validation Assessment for Study of Inflammatory Skin Disease
1. Assess validity of methods involved in molecular studies of the skin in inflammatory skin disease 2. Assess feasibility of methods for grafting fresh human skin (normal and diseased with inflammatory skin disease) onto an…
- Trial name
- NCT03796806
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Tooth Loss and Rehabillitation, Immediate Implant Placement in Mandibular Molar Extraction Sockets
Comparison Between Xenograft and Extended PRF as Jumping Gap Grafting Material Versus Natural Healing of the Socket Without Any Material.
This study aims to clinically and digitally evaluate immediate implants placed in mandibular molar extraction sockets and compare the outcomes of xenograft, e-PRF, and no grafting material within the jumping gap.
- Conditions
- Tooth Loss and Rehabillitation, Immediate Implant Placement in Mandibular Molar Extraction Sockets, Jumping Gap
- Trial name
- NCT07797452
- Testing
- Xenograft jumping gap filling material, e-PRF jumping gap filling material
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
AML - Acute Myeloid Leukemia
Evaluation of Combined Sensitising and Hypomethylating Therapy Outcomes in AML PDX
The goal of this observational study is to develop new ways to test new drug combinations to kill tumour cells, in patients with acute myeloid leukemia (AML).
- Trial name
- COSMOS-Avatar (NCT06782971)
- Where
- 4 sites in Australia
- Volunteers
- 25 people
- Sponsor
- Clinical Hub for Interventional Research (CHOIR)
Alveolar Ridge Deficiency
Ridge Preservation Comparing 2 Membranes
The purpose of this study is to compare the clinical and histologic outcomes for acellular dermal matrix and a nonresorbable membrane to determine if either provides a significant therapeutic advantage.
- Trial name
- NCT01905280
- Testing
- Non-resorbable membrane, Acellular dermal matrix
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Metastatic Breast Cancer
Patient Derived Breast Cancer Xenografts
This study will use tissue or body fluid acquired during standard procedures that are part of the patient's care for their cancer, such as surgery to remove tumor tissue or needle withdrawal of body fluid containing cancer cells.
- Trial name
- NCT01750164
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Implant Therapy
Clinical and Radiographic Assessment of the Outcomes of Dental Implant Inserted After Xenograft Socket Preservation in Posterior Maxilla
Clinical and Radiographic Assessment of the Outcomes of Dental Implant Inserted after Xenograft Socket Preservation in Posterior Maxilla: A Randomized Controlled Study
- Trial name
- NCT07001813
- Testing
- socket preserved, non preserved socket
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Periodontal Pocket, Periodontal Bone Loss
Using Xenograft Combined With Barrier Membrane to Improve the Formation of Deep Periodontal Pockets
To evaluate the clinical effect of site preservation after third molars extraction by using tooth extraction of third molars with site preservation using bio-oss and bio-guide in preventing the formation of deep periodontal…
- Conditions
- Periodontal Pocket, Periodontal Bone Loss, Impacted Third Molar Tooth
- Trial name
- NCT06318247
- Testing
- site preservation
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Liver Transplant
A Multicentre, Randomised, Open-label, Controlled, 12-month Follow-up Study to Assess Impact on Renal Function of an Immunosuppression Regimen Based on Tacrolimus Minimisation in Association With Everolimus in de Novo Liver Transplant Recipients.
Assuming greater efficacy in the prevention of acute rejection in the EVR arm with minimisation of TAC levels, the hypothesis of the present trial was that the introduction of EVR in combination with the minimisation of TAC…
- Trial name
- REDUCE (NCT02040584)
- Testing
- Minimisation of TAC, TAC + MMF + corticosteroids
- Where
- 20 sites in Spain
- Volunteers
- 217 people
- Sponsor
- Novartis Pharmaceuticals
Alveolar Bone Resorption, Sequela
Bone Material Comparison in Maxillary Sinus Augmentation
Hard and soft tissue deficiencies of an alveolar ridge arise as sequelae of tooth extraction when socket preservation is not applied.
- Conditions
- Alveolar Bone Resorption, Sequela, Tooth Extrusion
- Trial name
- NCT04433117
- Testing
- Shefabone, Bio-Oss
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mohanad Al-Sabbagh
Alveolar Bone Resorption
Comparison of Autogenous Dentin Matrix Versus Bovine-Derived Xenograft for Socket Preservation
The present study is a human, prospective, randomised controlled clinical trial will be conducted to explore and compare the clinical, radiographic and histomorphometric outcome of autogenous demineralised dentin(DDM) versus…
- Trial name
- NCT04239378
- Testing
- socket preservation
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Periodontitis, Periodontal Bone Loss
Non-incised Papillae Surgical Approach (NIPSA) and Connective Tissue Graft Plus Emdogain for Periodontal Defects
The present study pretends to show the results of combining a modification of the Non-incised papillae surgical approach (NIPSA) attempting to improve the outcome in the treatment of teeth with advanced periodontal support loss.
- Conditions
- Periodontitis, Periodontal Bone Loss, Periodontal; Lesion
- Trial name
- NCT03997578
- Testing
- NIPSA (Non-incised papilla surgical approach), NIPSA plus connective tissue graft
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Murcia
Alveolar Ridge Preservation
Alveolar Ridge Preservation Using Amniotic Chorion Membrane
the present study is to compare the amniotic chorion membrane (ACM) alone versus the amniotic chorion membrane combined with xenograft for their efficacy in alveolar ridge preservation procedures regarding volumetric changes…
- Trial name
- NCT04824235
- Testing
- Amniotic Chorion Membrane and Bio-Oss xenograft, Amniotic Chorion Membrane only
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Hams Hamed Abdelrahman