Clinical trials: Xenograft
Connective Tissue Graft, Volume Collagen Matrix Xenograft
Volumetric Dimensional Changes After Surgical Pontic Site Development Procedures With Connective Tissue Graft or Collagen Matrix
The aim of this research project is to compare two surgical procedures to improve soft tissue volume. Both procedures have already been validated, but despite their great clinical relevance, little data exists in the literature.
- Trial name
- NCT06335628
- Testing
- Geistlich Fibro-Gide®
- Where
- Switzerland
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Bern
Bone Loss
Evaluation of Marginal Bone Loss After Immediate Implant Placement in Esthetic Zone Without Xenograft.
Marginal bone loss in immediate implant placement in upper esthetic zone by comparing between non grafting in immediate implant placement with xenograft placement in other side.
- Trial name
- NCT03397316
- Testing
- xenograft placement .
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cairo University
Malignant Melanoma, Head and Neck Cancer
Tissue and Hematopoietic/Mesenchymal Stem Cell for Humanized Xenograft Studies in Melanoma and Squamous Head and Neck Cancer
The overall goal of this study is to develop a pre-clinical platform of melanoma and head and neck squamous cell cancer that will allow the investigators to learn more about these diseases and discover better and more…
- Trial name
- NCT02331134
- Testing
- Filgrastim
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Colorado, Denver
Lung Cancer
Lung Cancer Organoids and Patient Derived Tumor Xenografts
Extra tissue will be taken from patient during a procedure in standard of care. Also, through an existing line, 10ml of extra blood will be drawn.
- Trial name
- IPON-3 (NCT05092009)
- Testing
- Tissue and blood
- Where
- 3 sites in Netherlands
- Volunteers
- 600 people
- Sponsor
- Maastricht Radiation Oncology
Breast Cancer
Estrogen Receptor-Positive Breast Cancer Patient-Derived Xenografts
The investigators will establish a platform at Dartmouth-Hitchcock Medical Center to generate novel models of estrogen receptor alpha-positive (ER+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer, which…
- Trial name
- NCT02752893
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Alveolar Ridge Preservation
Alveolar Ridge Preservation With Layered Collagen and Xenograft
alveolar ridge preservation using deep collagen layer, xenograft and collagen membrane seal versus the use of xenograft and collagen membrane seal alone.
- Trial name
- NCT05683509
- Testing
- deep collagen layer, xenograft and collagen membrane, xenograft and collagen membrane
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Crestal Bone Loss
Effect of Vitamin D on Crestal Bone Loss Around Immediate Implant After Mandibular Premolars and Molars Extraction
What is the difference between grafting the jumping gap upon using xenograft mixed with topical vitamin D clinically regarding crestal bone level and implant stability, radiographically regarding crestal bone level after implant…
- Trial name
- vitD (NCT07065877)
- Testing
- vit D mixed with xenograft, only xenograft without vit D
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Periodontal Diseases, Intrabony Periodontal Defect
Papilla Preservation Technique in Combination With Tooth Enamel Proteins and Animal Derived Bone Graft in Treating Isolated Bone Defects Between Teeth
The present three-arm study compared the clinical and tomographic efficacy of the Entire Papilla Preservation Surgical Technique (EPPT) alone and combined with enamel matrix derivative (EMD) plus bone mineral derivedxenograph…
- Trial name
- NCT07119307
- Testing
- Entire Papilla Preservation Technique, Entire Papilla Preservation Surgical Technique (EPPT) alone, Entire Papilla Preservation Surgical Technique (EPPT) alone and combined with enamel matrix derivative (EMD)
- Where
- India
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Rungta College of Dental Sciences and Research
Implant, Zinc Status
Zinc Incorporated Bovine Derived- Hydroxyappatite Xenograft in Immediately Placed Implant
The aim of this study is to evaluate Clinical and radiographic effect of zinc incorporated bovine derived hydroxyapatite xenograft and bovine hydroxyapatite xenograft alone for immediately placed implant
- Trial name
- NCT07187609
- Testing
- Immediate implant with bovine drived hydroxyapatite xenograft., immediate implant with zinc incorporated bovine drived hydroxyapatite xenograft
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Tooth Extraction
Combination of Platelet-Rich Fibrin and Calcium Sulfate in Socket Augmentation
This study evaluated the effectiveness of socket grafting material, combination of plate-rich fibrin and calcium sulfate. 5 subjects were grafted with this material, 5 subjects were grafted with combination of plate-rich fibrin…
- Trial name
- NCT03851289
- Testing
- platelet-rich fibrin and calcium sulfate, platelet-rich fibrin and xenograft
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Immediate Dental Implant Placement, Immediate Implant Placement
Comparing the Position of Collagen Membrane During Immediate Implant Placement
evaluation of the use of collagen membrane inside the socket and outside it during immediate implant placement
- Conditions
- Immediate Dental Implant Placement, Immediate Implant Placement, Badly Decayed Teeth
- Trial name
- NCT04224935
- Testing
- Collagen membrane inside, Collagen membrane outside
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Alveolar Bone Loss, Socket Shield Technique
Socket Shield Technique With CGF and Xenograft for Immediate Implants
This prospective case series aims to evaluate the clinical and radiographic outcomes of immediate implant placement using the socket shield technique combined with concentrated growth factors (CGF) and xenograft in the esthetic…
- Conditions
- Alveolar Bone Loss, Socket Shield Technique, Bone Resorption, Immediate Dental Implant Placement
- Trial name
- CGF (NCT07520513)
- Testing
- Socket Shield Technique with Immediate Implant Placement and CGF + Xenograft
- Where
- Egypt
- Volunteers
- 7 people
- Sponsor
- Cairo University
Internal Sinus Lifting
Efficacy of Adjunctive Theravex Tissue Care® With Xenograft in Internal Sinus Lifting
The purpose of this clinical study is to evaluate the clinical and radiographic efficacy of Theravex Tissue Care Plus (Bone Bioactive Liquid) as an adjunct to a xenograft in crestal maxillary sinus elevation with simultaneous…
- Trial name
- NCT07627633
- Testing
- Internal Sinus lifting using Theravex-Xenpgraft mixture, Internal Sinus lifting using Xenpgraft alone
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Breast Cancer, Residual
Development of Patient Derived Xenografts (PDX) in Patients With Breast Cancer
Breast cancer patients who undergo neoadjuvant systemic therapy and have residual breast cancer identified at the time of surgery exhibit a high (>50%) risk of future life-threatening recurrences and death.
- Trial name
- NCT04703244
- Testing
- chemotherapy or endocrine therapy for breast cancer
- Where
- United States
- Volunteers
- 999 people
- Sponsor
- Mayo Clinic
Clinical Efficacy
Ridge Preservation Comparing a PTFE Nonresorbable Membrane to a Collagen Membrane
A non-resorbable PTFE (teflon) membrane will be compared to a resorbable collagen membrane when used for a post-extraction ridge preservation procedure to prevent the bone loss that typically occurs.
- Trial name
- NCT01900964
- Testing
- PTFE membrane, Collagen membrane
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Bone Loss in Jaw
Demineralized Bone Allograft Fibers Versus Particulate In Sinus Augmentation
The purpose of this clinical trial is to assess if the addition of DFDBA fibers to DBBM results in greater vital bone formation than the addition of DFDBA particles to DBBM.
- Trial name
- NCT06173791
- Testing
- DFDBA fibers, DFDBA particles, DBBM
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Atrophic Maxilla, Partial Edentulism
Prospective Study of Bone Augmentation With Lateral Sinus Lift and Osseointegration of Dental Implants
By using a split-mouth model in the maxilla, lateral sinus lift procedures will be performed using xenograft on one side vs autologous bone augmentation and PRF membranes on the other side.
- Trial name
- NCT07014085
- Testing
- "Histomorphometric Evaluation of Bone Augmentation Using Xenografts Versus Autologous Bone Grafts in Dental Implant Patients: A Comparative Clinical Study
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maria H. Pham
Alveolar Bone Resorption, Socket Preservation
Efficacy Of Eggshell-Derived Nanohydroxyapatite Based Mineralized Plasmatic Matrix Versus Xenogeneic Based Mineralized Plasmatic Matrix in Posterior Mandibular Socket Preservation
After tooth extraction, the alveolar bone, which supports the teeth, undergoes a natural resorption process. This bone loss can be significant, especially in the first few months post-extraction, leading to a reduction in both…
- Conditions
- Alveolar Bone Resorption, Socket Preservation, Wound Healing, Nano-hydroxyapatite
- Trial name
- NCT07404098
- Testing
- Socket preservation using eggshell-derived nanohydroxyapatite-based mineralized plasmatic matrix along with platelet-rich fibrin (PRF)., Socket preservation using deproteinized bovine bone mineral (DBBM) xenograft along with platelet-rich fibrin (PRF).
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
Partial Edentulism
Histologic Comparison of Healing After Tooth Extraction With Ridge Preservation Using Two Different Xenografts
The purpose of this study is to compare the speed of bone healing of the two most commonly used xenografts on the market, Bio-Oss® and Salvin-Oss® using a tooth extraction ridge preservation model in participants scheduled for…
- Trial name
- NCT03769376
- Testing
- Bio-Oss®, Salvin-Oss®
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Kidney Failure, Chronic
Porcine Kidney Xenotransplantation in Patients With End-Stage Kidney Disease
The mismatch between organ supply and demand results in the deaths of thousands of Americans each year. Our research group aims to solve this unmitigated health care crisis by translating advances in xenotransplantation to humans…
- Trial name
- NCT05340426
- Testing
- UKidney
- Where
- United States
- Sponsor
- University of Alabama at Birmingham