Clinical trials: Xenograft
Maxillary Diseases
Lateral Sinus Augmentation Using L-PRF as Sole Graft Material
Severe maxillary atrophy occurs after extraction of teeth in poster maxilla due to dimensional changes occur after removal; besides, sinus membrane pneumatization causes alveolar bone resorption, different classification for…
- Trial name
- NCT04160780
- Testing
- L-PRF, L-PRF mixed with xenograft, xenograft
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Alveolar Ridge Preservation
Polynucleotide-Hyaluronic Acid Gel With Xenograft for Alveolar Ridge Preservation
This randomized controlled clinical trial will evaluate the efficacy of polynucleotide-hyaluronic acid gel combined with xenograft and collagen membrane for alveolar ridge preservation following tooth extraction.
- Trial name
- NCT07771257
- Testing
- Polynucleotide-Hyaluronic Acid Gel With Xenograft, Xenograft With Collagen Membrane
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Edentulous Alveolar Ridge
Implant Placement in Mandibular Molar Xenograft Versus PRF
20 recruited patients indicated for immediate implant placement in mandibular molar patients are divided into 2 groups each group contain 15 patients, one group assigned for placement of bovine bone after molar extraction and…
- Trial name
- NCT03177356
- Testing
- extraction,implant placement,PRF, Exctraction,Implant placement,Bone graft
- Volunteers
- 20 people
- Sponsor
- Cairo University
Maxillary Sinus
Maxillary Sinus Elevation and Simultaneous Implant Placement
using gel foam [ absorbable gelatin ] in maxillary sinus elevation which act as a space maintainer and alternative to bone filler for new bone formation in the maxillary sinus and its advantages for patients undergoing maxillary…
- Trial name
- NCT03252366
- Testing
- GELFOAM, xenograft
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Cairo University
Kidney Neoplasm, Carcinoma, Renal Cell
Hyper-Personalized Medicine Using Patient Derived Xenografts (PDXovo) for Metastatic Solid Tumors
The Investigators will use novel PDX (patient-derived xenograft) technology to form xenografts using material from metastatic solid tumor patients.
- Conditions
- Kidney Neoplasm, Carcinoma, Renal Cell, Metastatic Solid Tumor
- Trial name
- PDXovo (NCT04602702)
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Sunnybrook Health Sciences Centre
TEETH EXTRACTION
Ridge Preservation Using a Ossix™ Bone vs Bio-Oss® Collagen
This randomized, parallel design, controlled study will assess the histologic healing of this Ossix™ Bone in humans and compare it to a Bio-Oss® Collagen that is well researched. Subjects will be enrolled into 2 groups.
- Trial name
- NCT04338516
- Testing
- Ossix™ Bone, Bio-Oss® Collagen
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Datum Dental LTD
Socket Preservation
Evaluation of Post-extraction Socket Preservation With Camelline Versus Bovine Deproteinized Xenograft
Alveolar ridge preservation following tooth extraction has the ability to maintain the ridge dimensions and allow the implant placement in an ideal position fulfilling both functional and aesthetic results.
- Trial name
- NCT03677479
- Testing
- socket preservation procedure
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Aortic Xenograft Hemodynamics
Comparison of TrIfecta and Perimount Magna Ease
The hemodynamic performance of two supraannular aortic xenografts (Trifecta, St. Jude Medical and Perimount Magna Ease, Edwards Lifescience) will be compared using rest- and stress echocardiography in a randomized prospective…
- Trial name
- NCT03021356
- Testing
- Aortic xenograft
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Kerckhoff Klinik
Triple Negative Breast Cancer
Patient-derived Xenograft (PDX) Modeling of Treatment Response for Triple Negative Breast Cancer
This study will determine if patient-derived tumor xenograft (PDX) mouse models can serve as a reliable model for treatment response for individual patients with triple negative breast cancer.
- Trial name
- NCT02247037
- Testing
- Chemotherapy
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Badly Decayed Teeth
Immediate Implant Placement in the Esthetic Zone With and Without Using Autogenous Mixed With Xenograft
Xenografts are graft materials derived from the inorganic portion of animal bones; the most common source is bovine the removal of the organic component are processed to remove their antigenicity, while the remaining inorganic…
- Trial name
- NCT04096209
- Testing
- autograft mixed with xenograft bone
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Cairo University
ESRD (End-Stage Renal Disease), Kidney Transplantation
Study to Evaluate the Safety and Efficacy of the 10 GE Xenokidney in Patients With ESRD
The purpose of this study is to evaluate the safety and efficacy of the 10 GE Xenokidney in patients with ESRD who are either not eligible for conventional allogeneic kidney transplantation (Group 1) or are on an Organ…
- Conditions
- ESRD (End-Stage Renal Disease), Kidney Transplantation, Xenotransplantation
- Trial name
- EXPAND (NCT06878560)
- Testing
- 10 GE Xenokidney
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- United Therapeutics
Horizontal Alveolar Bone Loss
Alveolar Ridge Augmentation With Curcumin Combined With Xenograft
A study was performed to investigate the effect of curcumin on the osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs) and its underlying potential mechanism.
- Trial name
- NCT04971382
- Testing
- Curcumin
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Ain Shams University
Pancreatic Cancer, Liver Metastases
A Study of Pancreatic Cancer in Xenografts From Liver Metastases
This is a feasibility study to perform image-guided liver biopsies in 25 patients who have pancreatic cancer with liver metastasis (cancer in the pancreas that has spread to the liver).
- Conditions
- Pancreatic Cancer, Liver Metastases, Tumor Tissue Biopsy, Blood Samples
- Trial name
- NCT01774643
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- University Health Network, Toronto
Ridge Augmentation
Autogenous Sticky Bone Plus Platelet-rich Fibrin Membrane Versus Xenograft With Collagen Membrane for Posterior Atrophic Mandible
Background: Teeth loss in the posterior mandible initiates residual ridge resorption, this causes difficulty in implant placement so ridge augmentation must be done either simultaneous with implant placement or in a staged…
- Trial name
- NCT07825896
- Testing
- autogenous sticky bone + PRF membrane, Xenograft + collagen membrane
- Where
- Egypt
- Volunteers
- 26 people
- Sponsor
- Alexandria University
Atrophic Maxilla
Assessment of Bone Quality and Quantity for Three Dimensional Bone Augmentation for Maxilla Using Patient Specific Titanium Meshes Loaded With Bone Marrow Aspirate Mixed With Xenograft Versus Xenograft Mixed With Autografts Only: a Randomized Clinical Trial
Assessment of bone quality and quantity for three dimensional bone augmentation for maxilla using titanium meshes loaded with bone marrow aspirate mixed with xenograft versus xenograft mixed with autografts only
- Trial name
- NCT05400044
- Testing
- Three dimensional maxillary bone augmentation
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Badly Broken Maxillary Premolars Indicated for Extraction
Immediate Implants in Maxillary Premolar Region Using Xenograft vs Allograft
Immediate implant placement has the disadvantage of difficulty in obtaining primary stability, lack of adequate soft tissue coverage and also the control of the implant position is difficult in addition to the cost of the graft.
- Trial name
- NCT03716323
- Testing
- immediate premolar implant with xenograft and allograft
- Volunteers
- 42 people
- Sponsor
- Cairo University
Horizontal Ridge Deficiency
The Horizontal Ridge Augmentation Using Equine Xenograft and a Collagenated Porcine Cortical Lamina
The primary aim of this study is to clinically, radiographically and histologically evaluate the lateral bone augmentation of the soft porcine cortical lamina (OsteoBiol®) using equine-derived bone particles (OsteoBiol®)
- Trial name
- NCT04376060
- Testing
- Gen-Os®; The soft lamina (OsteoBiol®)
- Where
- Lebanon
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Immediate Dental Implant Placement
Effect of Theravex Tissue Care on Implant Stability
The aim of this randomized clinical trial is to evaluate the clinical and radiographic outcomes of using Bone Bioactive Liquid (Theravex) compared to Xenograft and a combination therapy (Theravex + Xenograft) during immediate…
- Trial name
- NCT07707388
- Testing
- Bone Bioactive Liquid, Bovine-derived Xenograft, Immediate Implant Placement
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Clinical Efficacy
Ridge Preservation Comparing an Intrasocket Graft Alone to an Intrasocket Graft Plus a Facial Overlay Graft
The purpose of this study is to compare two methods of ridge preservation in the maxillary anterior esthetic zone to determine the best method to establish adequate bone and soft tissue to accommodate implant placement.
- Trial name
- NCT01431131
- Testing
- Intrasocket graft, Intrasocket plus facial overlay graft
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Immediate Implant Placement in Mandibular Molar Extraction Sockets
Computer Guided Immediate Implant Placement in Mandibular Molars Using Patient Specific 3D Printed Polylactic Acid Graft Versus Conventional Immediate Implant Placement With Xenograft
This randomized controlled clinical trial will evaluate a computer-guided immediate implant placement technique in non-restorable mandibular molars using a patient-specific 3D-printed polylactic acid (PLA) graft and implant…
- Trial name
- RCT (NCT07774052)
- Testing
- Patient-Specific 3D-Printed PLA Socket Guide and Root-Form Scaffold, Conventional Immediate Implant Placement
- Where
- Egypt
- Volunteers
- 17 people
- Sponsor
- Mahmoud Fawzy Mahmoud Mohamed