Clinical trials: Young Adult Cancer
Breast Cancer, Lymphoma
Adolescent and Young Adult Cancer Patients: Cognitive Toxicity on Survivorship (ACTS)
This study aims to evaluate the prevalence, biological mechanism and survivorship impact of cognitive toxicity among adolescent and young adult (AYA) patients diagnosed with curable cancers.
- Conditions
- Breast Cancer, Lymphoma, Germ Cell Tumor, Cognitive Impairment
- Trial name
- NCT03476070
- Where
- 3 sites in Singapore
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Radiation Disease
Pelvic Radiation Disease in Childhood Cancer Survivors
This study aims to characterise the impact of radiotherapy on physical symptoms and quality of life in childhood and young adult cancer survivors.
- Trial name
- NCT05533541
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Neurofibromatosis
Acceptance and Commitment Therapy for Adolescents and Young Adults With Neurofibromatosis and Chronic Pain
Background: Neurofibromatosis type 1 (NF1) is a genetic disorder that can cause frequent and significant pain. This pain can have a severe impact on a person s quality of life.
- Trial name
- NCT01633008
- Testing
- ACT Workshop
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Infections, Papillomavirus
Follow-up Study to Evaluate the Safety and Immunogenicity of a HPV Vaccine (580299) in North America
Infection with human papillomavirus (HPV) has been clearly established as the central cause of cervical cancer. This study will further evaluate induction of immune memory and anamnestic responses in women who previously took…
- Trial name
- NCT00546078
- Testing
- Cervarix™
- Where
- 17 sites in United States, Canada
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Pediatric Cancer
Pilot Evaluation of a Healthy Lifestyle Intervention for Adolescent and Young Adult Survivors of Pediatric Cancer
This is a feasibility and acceptability trial to test a newly developed healthy lifestyle intervention for adolescent and young adult survivors of pediatric cancer.
- Trial name
- NCT04839952
- Testing
- Healthy Lifestyles, Education-Only Control
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins All Children's Hospital
Cancer, Vaping
Study of Vaping Use Among Adolescent and Young Adult Patients With Cancer
The purpose of this study is to learn more about how adolescent and young adult (AYA) cancer patients, their parents and caregivers (referred to as a carebuddy in this study), and their healthcare providers think about and…
- Trial name
- NCT07860801
- Testing
- Study assessments
- Where
- 7 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Infections, Papillomavirus
Human Papilloma Virus (HPV) Vaccine Immunogenicity and Safety Trial in Young and Adult Women With GSK Biologicals' HPV-16/18
Infection with human papillomavirus (HPV) has been clearly established as the central cause of cervical cancer. Indeed, certain oncogenic types of HPV can infect the cervix (part of the uterus or womb).
- Trial name
- NCT00196937
- Testing
- Cervarix
- Where
- 6 sites in Germany, Poland
- Volunteers
- 667 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Unspecified Childhood Solid Tumor, Protocol Specific
Telephone-Based Cancer Education With or Without Telephone-Based Counseling in Young Participants
RATIONALE: Telephone-based cancer education and counseling may help participants learn about ways of preventing cancer and choose a lifestyle that will help them stay healthy as they grow older.
- Trial name
- NCT00459238
- Testing
- counseling intervention, educational intervention
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Cancer
Evaluation of a Psychosocial Support Model for Adolescents and Young Adults Newly Diagnosed With Cancer
Rational: Adolescents and young adults (AYAs) newly diagnosed with cancer is a small but vulnerable group with many psychosocial needs persisting for a long time.
- Trial name
- NCT06979843
- Testing
- A psychosocial model
- Where
- 2 sites in Sweden
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Diabetes Risk, CVD Risk
Effectiveness of a Self-health Assessment Mobile Application in Young-to-midlife Adults in Hong Kong
This project aims to compare the effectiveness of Wellnuts, an evidence-based, algorithm-driven self-health assessment mobile application, in empowering asymptomatic young-to-midlife adults in Hong Kong, promoting health…
- Conditions
- Diabetes Risk, CVD Risk, Colorectal Cancer, Lung Cancer
- Trial name
- NCT07720245
- Testing
- Wellnuts app intervention, Web-based health resources
- Where
- Hong Kong
- Volunteers
- 574 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Cancer
Cancer Prevention for Young Rural Adults
Young adults aged 18-26 engage in a number of behaviors that increase their risk of developing cancer later in life including sedentary lifestyles, unhealthy eating, nicotine produce us, heavy drinking of alcohol, increased UV…
- Trial name
- NCT05618158
- Testing
- 4 Corners Rural Health Cancer Prevention
- Where
- 5 sites in United States
- Volunteers
- 1,796 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Advanced Cancer
Videos for Advance Care Planning in Young Adults
This study is a randomized trial of adolescent and young adults with advanced cancer and their caregivers to assess preferences for care in advanced cancer.
- Trial name
- NCT04149704
- Testing
- ACP video decision aid, Usual Care-
- Where
- 3 sites in United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
HPV, HIV
Long Term Immunogenicity of Quadrivalent Human Papillomavirus Vaccine (Gardasil®)in HIV-infected Adolescents and Young Adults
Infection with human immunodeficiency virus (HIV) is an important risk factor for HPV infection and the development of HPV-associated lesions in female and male anogenital tract.
- Trial name
- NCT01512784
- Testing
- Quadrivalent Human Papillomavirus (6, 11, 16 and 18) vaccine (Gardasil ®)
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Milan
Smoking, Smoking Cessation
Evaluation of National Cancer Institute Young Adult Stop-Smoking Program
Background: Researchers want to see how well the QuitTXT text-message program helps smokers ages 18 29 stop smoking. This is part of a larger online stop-smoking program by the National Cancer Institute.
- Conditions
- Smoking, Smoking Cessation, Cigarette Smoking, Tobacco, Smoking
- Trial name
- NCT01885052
- Testing
- QuitTXT Study, Low Contact
- Where
- United States
- Volunteers
- 4,432 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Obesity, Malignant Neoplasm
A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant
This early phase I trial studies how well a behavioral weight loss intervention consisting of a smartphone application and coaching works for the promotion of weight loss in adolescents and young adults after a stem cell…
- Trial name
- NCT04453072
- Testing
- Interview, Media Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jonsson Comprehensive Cancer Center
Polycystic Ovarian Syndrome (PCOS)
Polycystic Ovarian Syndrome (PCOS) Biomarker Evaluation Study
The purpose of the study is to validate recently identified biomarkers for the identification of PCOS in adolecent and young adult women.
- Trial name
- PHOEBE (NCT06642831)
- Where
- Germany
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- University Hospital Erlangen
Childhood Cancer
COMUNICAR: Community-Led Family-Centered Communication for Cancer Survivorship Care
This study will test a novel intervention to facilitate family-centered communication among Hispanic/Latino (H/L) young adult childhood cancer survivors (YA-CCS), their support persons, and their clinicians through collaboration…
- Trial name
- NCT07606443
- Testing
- Family-Centered Communication Intervention
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Stanford University
Infections, Papillomavirus
Human Papillomavirus Vaccine Safety & Immunogenicity Trial in Healthy Young Adult Women With HPV Vaccine (GSK1674330A)
Infection with human papillomavirus (HPV) has been clearly established as the central cause of cervical cancer. Indeed, certain oncogenic types of HPV can infect the cervix (part of the uterus or womb).
- Trial name
- NCT00478621
- Testing
- GSK Biologicals' HPV vaccine (GSK1674330A), Cervarix TM
- Where
- 3 sites in Belgium
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Infections, Papillomavirus
Follow-up Study of GSK Biologicals' Human Papilloma Virus (HPV) Vaccine to Prevent Cervical Infection in Young Adults
Human Papilloma virus (HPV) are viruses that cause a common infection of the skin and genitals in men and women. Several types of HPV infection are transmitted by sexual activity and, in women, can infect the cervix (part of the…
- Trial name
- NCT00120848
- Testing
- HPV 16/18 VLP AS04
- Where
- 27 sites in United States, Brazil and 1 more
- Volunteers
- 776 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Cancer, Brain Tumor
Medical Treatment Decision Making Using Adaptive Conjoint Analysis
In the setting of progressive or recurrent cancer, adolescent and young adult (AYA) patients, parents, and healthcare providers (HCP) are faced with multiple therapeutic options.
- Conditions
- Cancer, Brain Tumor, Solid Tumor, Leukemia
- Trial name
- NCT02608307
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital