Clinical trials: Young Adults
Tobacco Cigarette Smoking
Testing the Impact of Smartphone-based Messaging to Support Young Adult Smoking Cessation - Pilot
Clinical practice guidelines for smoking cessation emphasize cognitive behavioral therapy (CBT) to help patients develop coping strategies for urges.
- Trial name
- NCT05991934
- Testing
- Smartphone-based intervention messages
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Hamstring Shortness
Acute Effects of Foam Roller and Mulligan Technique on Hamstring Flexibility
The hamstring muscle group is located at the back of the thigh. Due to its structure and people's habits, shortness in this muscle group is frequently observed.
- Trial name
- NCT07078734
- Testing
- Foam roller, Therapist-assisted Mulligan Straight Leg Raise
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Smoking
Functional Capacity, Subjective Dyspnea and Fatigue in Smokers
Smoking remains a significant public health problem among the young adult population. Epidemiological studies in Turkey show a steadily decreasing age of smoking initiation and a remarkably high rate of smoking among…
- Trial name
- NCT07520981
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Istinye University
Leukemia
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00558519
- Testing
- cyclophosphamide, cytarabine, daunorubicin hydrochloride
- Volunteers
- 318 people
- Sponsor
- Alliance for Clinical Trials in Oncology
T-cell Adult Acute Lymphoblastic Leukemia
Multicenter Study of Risk-adapted Treatment for T-lineage ALL of Young Adults (18-59 Years Old)
The purpose of this study is to evaluate the efficacy of nelarabine-based consolidation and maintenance therapy in term of relapse-free survival (RFS) in high-risk (HR) patients.
- Trial name
- GRAALL-2014/T (NCT02619630)
- Testing
- nelarabine
- Where
- France
- Volunteers
- 275 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healthy Young Adults
Effect of Kinesio Taping on Pulmonary Function and Forward Shoulder Posture FSP of Young Adults
The aim of the study is to evaluate the effect of kinesio taping on pulmonary function and forward shoulder posture in young adults.
- Trial name
- FSP (NCT05876663)
- Testing
- Kinesio Taping, Conventional physiotherapy protocol
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Osteosarcoma
A Phase I Feasibility And Safety Study of Fluorescein-Specific (FITC-E2) CAR T Cells In Combination With Parenterally Administered Folate-Fluorescein (UB-TT170) For Osteogenic Sarcoma
The purpose of this study is to see if a new treatment could help patients who have osteosarcoma that does not go away with treatment (is refractory) or comes back after treatment (is recurrent).This study is testing a…
- Trial name
- NCT05312411
- Testing
- SCRI-E2CAR_EGFRtv1, UB_TT170
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Seattle Children's Hospital
Symptom Management, Young Adult Cancer
Reducing Health Disparity of Physical Functioning Among Young Adult Cancer Patients of Color
The purpose of the study is to pilot test of PAfitME™ among (1) young adults (YA) cancer patients of color (POC) (Analytic Sample [N=36] after attrition of 30%) and (2) YA cancer patients of White (POW) (Analytic Sample [N=36]…
- Conditions
- Symptom Management, Young Adult Cancer, Physical Activity, Gaming
- Trial name
- NCT07715344
- Testing
- PAfitME™
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- University of Alabama at Birmingham
Young Adult Health, Young Adults
Effects of Passive Recovery Methods After High-Intensity Cycling Exercise
This randomized crossover trial will investigate the acute effects of five passive recovery interventions following a standardized high-intensity cycling exercise protocol.
- Trial name
- RECOVER-CYCLE (NCT07652398)
- Testing
- High-Intensity Cycling Exercise Protocol, Doctor Life MK400L Sequential Intermittent Compression Device, Intelect Neo Therapy System with Chattanooga Intelect Neo Vacuum Module
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Drug Addiction, Technology Addiction
Relationship of Addictions to Obesity, Physical Activity and Vascular Ageing in Young Adults
This is a cross-sectional observational study whose objective is to analyse the relationship between behavioural addictions and drug addictions with obesity, physical activity, sedentary lifestyle, arterial stiffness and vascular…
- Conditions
- Drug Addiction, Technology Addiction, Young Adult
- Trial name
- NCT05866133
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Sexual Health
Assessment of the Psychosocial Sexual Health Competencies of Young Adults Born in France (including Those Whose Parents Were Born Abroad), and Proposal of a Sexual Health Promotion Model Adapted to the Needs Identified.
Every year, between 4,000 and 6,000 people discover their seropositivity to the human immunodeficiency virus (HIV). The dynamics of new discoveries vary according to sexual orientation and birthplace.
- Trial name
- ECOSSE (NCT06825247)
- Where
- France
- Volunteers
- 1,500 people
- Sponsor
- Centre Hospitalier le Mans
Genetic Predisposition
Outcomes of Health Care Transition for AYA With a Cancer Predisposition
This observational study evaluates whether adolescents and young adults (AYAs) with a cancer predisposition syndrome (CPS) establish and maintain adult health care and continue CPS-specific cancer surveillance after graduating…
- Trial name
- OnTRAC (NCT07456904)
- Testing
- Readiness Assessment, Transition Outcomes Survey A, Transition Outcomes Survey B
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- St. Jude Children's Research Hospital
Cerebral Palsy, Cerebral Palsy, Mixed
10-week Leucine Supplementation in Cerebral Palsy
The purpose of this study is to assess the effects of 10-weeks leucine supplementation on muscle growth, metabolism, body composition, inflammation and wellbeing in adolescents and young adults with CP.
- Conditions
- Cerebral Palsy, Cerebral Palsy, Mixed, Cerebral Palsy Ataxic
- Trial name
- NCT03668548
- Testing
- Leucine
- Where
- 2 sites in United Kingdom
- Volunteers
- 25 people
- Sponsor
- St Mary's University College
Genetic Predisposition to Disease, Genetic Predisposition
Enhancing Information Management for Young Adults After Genetic Cancer Risk Testing
This research is being done to develop the electronic platform Nest for young adults (ages 18-39) who have had prior cancer genetic testing.
- Trial name
- NCT05759143
- Testing
- Nest Platform
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
CNS 2a, CNS 2b
Wee1 Kinase Inhibitor AZD1775 and Combination Chemotherapy in Treating Children, Adolescents and Young Adults With Relapsed or Refractory Acute Myeloid Leukemia
This phase I trial studies the side effects and best dose of wee1 kinase inhibitor AZD1775 when given together with fludarabine, cytarabine, and filgrastim (FLAG) combination chemotherapy in treating children, adolescents and…
- Conditions
- CNS 2a, CNS 2b, CNS 2c, CNS1
- Trial name
- NCT02791919
- Testing
- Cytarabine, Filgrastim, Fludarabine Phosphate
- Sponsor
- National Cancer Institute (NCI)
Coping Behavior, Emotional Distress
Creative Arts Diabetes Initiative for Youth/Young Adults Transitioning to Adult Care
The Creative Arts Diabetes Initiative will offer facilitated art therapy with a group/peer-support environment to two groups of youth/young adults, one with type 1 diabetes, and one with type 2 diabetes.
- Conditions
- Coping Behavior, Emotional Distress, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2
- Trial name
- CADI (NCT02790892)
- Testing
- Art therapy - pre and post test measures
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Manitoba
Drug Use, Substance Use
Organization-level Youth Engagement Approach for Substance Misuse Prevention
This study will consist of a small pilot Randomized Controlled Trial (RCT). Four prevention organizations will be randomized either to include Youth Engagement in prevention efforts (treatment) or not (control).
- Conditions
- Drug Use, Substance Use, Opioid Use, Substance Misuse
- Trial name
- NCT05736211
- Testing
- Organization-level Youth Engagement prevention strategy
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
FHA (Functional Hypothalamic Amenorrhea)
Romosozumab as an Adjunct to Physiologic Estrogen Replacement in Functional Hypothalamic Amenorrhea
The goal of this study is to determine whether romosozumab will improve bone density in girls and women with functional hypothalamic amenorrhea (cessation of the menstrual period due to intense exercise, stress, or an eating…
- Trial name
- NCT06533865
- Testing
- Romosozumab, Zoledronic acid
- Where
- 2 sites in United States
- Volunteers
- 114 people
- Sponsor
- Massachusetts General Hospital
Myopia
Changes in Eye Shape With Myopia Management Interventions
The goal of this clinical trial is to study changes in eye shape of nearsighted young adults using low-dose atropine eye drops or soft multifocal contact lenses.
- Trial name
- NCT06450132
- Testing
- Atropine Ophthalmic, MiSight 1-day disposable contact lenses
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Down Syndrome, Obstructive Sleep Apnea
Computer Models of Airways in Children and Young Adults With Sleep Apnea and Down Syndrome
The purpose of this research study is to develop a way of predicting with computers how surgery on the airway will affect night time breathing called Obstructive Sleep Apnea (OSA) in children with Down Syndrome.
- Trial name
- DYMOSA (NCT01902407)
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
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