Clinical trials: Young Adults
Lymphoma, Neurotoxicity
Combination Chemotherapy in Treating Younger Patients With Hodgkin Lymphoma
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00666484
- Testing
- cyclophosphamide, doxorubicin hydrochloride, etoposide
- Where
- 5 sites in United Kingdom
- Volunteers
- 47 people
- Sponsor
- University College, London
White Spot Lesions, Dental Plaque
AI-Generated WhatsApp Reminders vs. No Reminders: Impact on Oral Health in Young Adults
This randomized controlled trial aims to evaluate the effectiveness of artificial intelligence-generated WhatsApp reminders on improving oral hygiene practices among individuals aged 20-40 years visiting the periodontal clinic at…
- Conditions
- White Spot Lesions, Dental Plaque, Oral Hygiene, Oral Health
- Trial name
- NCT06897033
- Testing
- Health education followed by AI-generated Whatsapp reminders, Oral Health Education
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Physical Activity, Quality of Life
Improving Physical Activity in Young Adult Cancer Survivors
The Primary Goal is to conduct a 12 week pilot randomized controlled trial (RCT) of the Fitbit Flex, a popular, affordable, wearable physical activity tracking device, and the Fitbit mobile health (mHealth) app.
- Trial name
- NCT03233581
- Testing
- Fitbit + Facebook + Coaching Group, Fitbit only
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Cancer
A Stress Management and Resiliency Program for Adolescent and Young Adult Survivors
This research study aims to explore the feasibility and acceptability of an adapted resiliency group program, called the Relaxation Response Resiliency Program (3RP-AYA), to reduce stress and promote stress-management among…
- Trial name
- NCT03768336
- Testing
- Waitlist control, 3RP-AYA
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Massachusetts General Hospital
Healthy
The Anabolic and Catabolic Effect of Loaded and Unloaded Exercise on Articular Cartilage Health
The serum concentration of cartilage oligomeric matrix protein (sCOMP) has been considered a mechano-sensitive biomarker of articular cartilage turnover, and N-propeptide of type II collagen (PIIANP) is a proposed biomarker of…
- Trial name
- NCT05925244
- Testing
- Control Condition, +12% Body Mass, -12% Body Mass
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Respiratory Tract Infection, Vitamin D Deficiency
Cholecalciferol Intervention to Prevent Respiratory Infections Study
This is a feasibility double-blind randomised controlled trial in 32 participants. It evaluates the feasibility of a full trial which will examine the efficacy of weekly supplementation of cholecalciferol (vitamin D3) relative to…
- Trial name
- CIPRIS (NCT01549938)
- Testing
- Cholecalciferol
- Where
- Australia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Menzies Institute for Medical Research
eTRE (Early Time Restricted Eating), lTRE (Late Time Restricted Eating)
Effect of Early Eating on Body Composition
To our knowledge, as of this day there are only four studies which examined the effects of eTRE with a duration of 12 weeks. There are no studies that examined this phenomenon beyond 12 weeks, one study that lasted five weeks and…
- Trial name
- NCT04679155
- Testing
- Eating Time Restriction
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Western University, Canada
Alcohol Misuse
Mobile Alcohol Use Intervention
This study aims to examine the feasibility and acceptability of a mobile health intervention to reduce alcohol use and related consequences among young adults.
- Trial name
- NCT07126613
- Testing
- Mobile Health Intervention to Reduce Alcohol Use Among Young Adults
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
AYA Cancer Patients, AYA Cancer Survivors
the Challenges of Young Adults With Cancer
The study aims to describe unmet needs of Adolescent \& Young Adults (AYA) with gastrointestinal and breast cancers in relation to: a) quality of life, b) education, c) finances and Insurance, and d) childbearing and…
- Trial name
- AYANDRA (NCT06594510)
- Where
- Italy
- Volunteers
- 580 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Mucopolysaccharidosis II
A Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) vs Idursulfase in Pediatric and Young Adult Participants With Neuronopathic (nMPS II) or Non-Neuronopathic Mucopolysaccharidosis Type II (nnMPS II)
This is a Phase 2/3, multiregional, two-arm, double-blind, randomized, active (standard-of-care)-controlled study of the efficacy and safety of tividenofusp alfa (DNL310), an investigational central nervous system (CNS)-penetrant…
- Trial name
- COMPASS (NCT05371613)
- Testing
- tividenofusp alfa, idursulfase
- Where
- 30 sites in United States, Argentina and 12 more
- Volunteers
- 65 people
- Sponsor
- Denali Therapeutics Inc.
Dental Plaque
Efficacy of Miswak in Oral Hygiene Maintenance
Miswak has been recommended by world health organization for oral hygiene because of its availability, beneficial effect and affordability.
- Trial name
- NCT04561960
- Testing
- Fluoride toothpaste, Toothpaste Product, Toothbrush
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Kidney Cancer
Impact of Tumour 1q Gain in French Pediatric and Young Adult Patients With Renal Tumours
French patients with nephroblastoma (Wilms tumour, WT) have been treated for > 40 years according to International Society of Paediatric Oncology (SIOP) protocols with currently 267 centres across 28 countries collaborating…
- Trial name
- UMBRELLA (NCT04005820)
- Testing
- Radiologic Centralized Review, Tissue sample (tumor, sung, urine)
- Where
- France
- Volunteers
- 510 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Young Healthy Adults
Effect of High-Intensity Interval Training Exercise on Cognitive Function of Young Adults
To explore the sustainability of the acute effect of High Intensity Interval Training (HIIT) on executive function in young adults.
- Trial name
- NCT06621550
- Testing
- High Intensity Interval Training
- Where
- Hong Kong
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Cancer Survivor
Three-Factor Eating Questionnaire in Measuring Eating Behavior in Adolescent and Young Adult Survivors of CNS Tumors
This trial studies how the Three-Factor Eating Questionnaire works in measuring eating behavior in adolescent and young adult survivors of central nervous system (CNS) tumors.
- Trial name
- NCT01682824
- Testing
- Nutritional Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- M.D. Anderson Cancer Center
Cigar Smoking
The Impact of Cigarillo Warnings on Purchasing
The purpose of this study is to determine whether different cigarillo warning formats (pictorial, FDA-proposed text-only, current Surgeon General text-only) reduces demand for cigarillos.
- Trial name
- NCT05434013
- Testing
- Cigarillo warnings-Surgeon General Text-Only, Cigarillo warnings-FDA proposed text-only, Cigarillo warnings-Pictorial
- Where
- United States
- Volunteers
- 1,578 people, healthy volunteers welcome
- Sponsor
- Boston University
Hematopoietic Neoplasm, Malignant Solid Neoplasm
Addressing Financial Hardship in Adolescent and Young Adult Cancer Survivors
This study seeks to develop, test, and revise an intervention designed to address financial hardship (FinFit) among adolescent and young adult (AYA) cancer survivors.
- Conditions
- Hematopoietic Neoplasm, Malignant Solid Neoplasm, Lymphatic System Neoplasm
- Trial name
- FinFit Aim 1 (NCT06881108)
- Testing
- CHAT Core Functions, LIFT Core Functions, Member-Checking Process
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Wake Forest University Health Sciences
Anxiety
Effects of Tai Chi Chuan on Psychobiological Indicators of Anxiety and Sleep Quality in Young Adults
The purpose of this study is to determine the feasibility of a 10-week tai chi chuan intervention as a treatment for anxiety and sleep quality in young adults.
- Trial name
- NCT01624168
- Testing
- Anxiety Management Education, 10 week tai chi intervention, Enhanced tai chi instruction
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Hypothalamic Obesity, Hypothalamic Tumor
Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity
Hypothalamic obesity (HO) refers to the substantial weight gain that often complicates hypothalamic brain tumors. Children with this treatment-recalcitrant form of obesity have excess rates of metabolic sequelae compared to…
- Conditions
- Hypothalamic Obesity, Hypothalamic Tumor, Craniopharyngioma
- Trial name
- NCT06299891
- Testing
- Phentermine / Topiramate Extended Release Oral Capsule [Qsymia]
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Seattle Children's Hospital
Depressive Disorder, Anxiety Disorders
StayFine: Personalised Relapse Prevention of Anxiety and Mood Disorders in Youths
The current study examines the effectiveness of the StayFine app for relapse prevention of anxiety or depressive disorders in youth using a randomized controlled trial.
- Trial name
- StayFine (NCT05551468)
- Testing
- StayFine guided app-based personalised intervention modules, StayFine app-based monitoring
- Where
- Netherlands
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Ggz Oost Brabant
Sickle Cell Anemia
Study of Efficacy, Safety and Tolerability of ACZ885 (Canakinumab) in Pediatric and Young Adult Patients With Sickle Cell Anemia
The study assesses the efficacy, safety and tolerability of ACZ885 (canakinumab) in pediatric and young adult patients with sickle cell anemia (SCA).
- Trial name
- NCT02961218
- Testing
- ACZ885
- Where
- 15 sites in United States, Canada and 5 more
- Volunteers
- 49 people
- Sponsor
- Novartis Pharmaceuticals
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