Clinical trials: Young Adults
Pediatric Cancer, Survivorship
Development and Evaluation of a Screening Approach for Sexual Dysfunction in AYA Patients With and Surviving Childhood Cancer
Prior research determined adolescent and young adult-aged childhood cancer survivor (AYA-CCS) and medical provider acceptability of the SexFS Brief in a controlled research setting.
- Trial name
- NCT05524610
- Testing
- Sexual Function Screening Approach
- Where
- 2 sites in United States
- Volunteers
- 205 people
- Sponsor
- University of Colorado, Denver
Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)
A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations
Regeneron is conducting a study of an investigational new drug called DB-OTO. DB-OTO is a gene therapy that is being developed to treat pediatric and adult participants who have severe-to profound and profound hearing loss due to…
- Trial name
- CHORD (NCT05788536)
- Testing
- DB-OTO
- Where
- 17 sites in United States, Germany and 3 more
- Volunteers
- 36 people
- Sponsor
- Regeneron Pharmaceuticals
Infections, Papillomavirus
Human Papilloma Virus (HPV) Vaccine Efficacy Trial Against Cervical Pre-cancer in Young Adults With GlaxoSmithKline (GSK) Biologicals HPV-16/18
Human Papilloma virus (HPV) are viruses that cause a common infection of the skin and genitals in men and women. Several types of HPV infection are transmitted by sexual activity and, in women, can infect the cervix (part of the…
- Trial name
- NCT00122681
- Testing
- Cervarix™, Havrix™-based investigational formulation
- Where
- 138 sites in United States, Australia and 12 more
- Volunteers
- 18,729 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy Aging
Accuracy of Prediction Equations to Calculate Maximum Strength
Resistance exercise training (RT) is a key component of health related exercise programs. However, an accurate specification of RT load prescription is essential for effective and safe achievement of training aims.
- Trial name
- NCT06718699
- Testing
- resistance exercise tests
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Osteoporosis, Obesity
Impact of Milk and Yogurt Supplementation on Bone Health, Body Composition, and Gut Microbiota in Canadian Young Adults
Milk and dairy products contain significant amounts of nutrients that contribute to optimal health - nutrients like calcium, vitamin D, and high-quality protein.
- Trial name
- NCT06265246
- Testing
- Habitual Diet + Milk, Habitual Diet + Yogurt
- Where
- Canada
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Epilepsy, Dravet Syndrome
GWPCARE2 A Study to Investigate the Efficacy and Safety of Cannabidiol (GWP42003-P) in Children and Young Adults With Dravet Syndrome
To investigate the potential antiepileptic effects of cannabidiol (GWP42003-P) in children and young adults with Dravet syndrome.
- Trial name
- NCT02224703
- Testing
- GWP42003-P
- Where
- 38 sites in United States, Australia and 4 more
- Volunteers
- 199 people
- Sponsor
- Jazz Pharmaceuticals
rTMS Stimulation, Autonomy
Repetitive Transcranial Magnetic Stimulation Primed Self-controlled Practice on Motor Learning
This study aims to investigate the additive effects of combining self-controlled practice with repetitive transcranial magnetic stimulation (rTMS) pretreatment on motivation enhancement and motor learning performance in healthy…
- Conditions
- rTMS Stimulation, Autonomy, Healthy Young Adults
- Trial name
- NCT07197346
- Testing
- rTMS - cTBS (Continuous Theta-Burst Stimulation), Self-controlled (autonomy), Yoked Practice
- Where
- Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Improved Body Composition
PILATES AND AEROBIC TRAINING ON BODY COMPOSITION IN YOUNG ADULTS
Pilates exercises have been shown to be effective for a range of outcomes; however, it is unclear whether they can effectively contribute to fat mass reduction, especially when compared with a technique known to be effective for…
- Trial name
- NCT07107061
- Testing
- Pilates exercises plus aerobic exercise, Pilates exercises, Aerobic exercise
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual do Norte do Parana
Friedreich's Ataxia
Safety, Tolerability and Efficacy of ACTIMMUNE® Dose Escalation in Friedreich's Ataxia
The purpose of this phase 3 randomized, multi-center, double-blind, placebo-controlled study is to evaluate the efficacy and safety of ACTIMMUNE® (interferon-γ 1b) in the treatment of Friedreich's Ataxia (FA) and to evaluate the…
- Trial name
- STEADFAST (NCT02415127)
- Testing
- Interferon γ-1b
- Where
- 4 sites in United States
- Volunteers
- 92 people
- Sponsor
- Amgen
Infant,Premature
Cardiac Function and Metabolism in Young Adults Born Premature (PET-MRI)
The purpose of this research is to determine the effect of premature birth on later heart function and metabolism.
- Trial name
- PET-MRI (NCT03245723)
- Testing
- Pulmonary Function Testing, Electrocardiogram, Positron Emission Tomography
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Autism
The Feasibility of a Remote Problem-Solving Intervention for Autistic Adolescents or Young Adults and a Caregiver
This project seeks to evaluate the feasibility and acceptability of a remote metacognitive strategy training intervention in transition-age autistic adolescents and young adults and a primary caregiver.
- Trial name
- NCT07216196
- Testing
- Pathways and Resources for Engagement and Participation (PREP)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Missouri-Columbia
Cancer
Young Adult Infusion Space Experience Satisfaction Survey
The purpose of this study is to compare the satisfaction of Adolescent and Young Adults (AYA) receiving treatment in two different infusion spaces at the North Carolina Basnight Cancer Hospital (NCBCH).
- Trial name
- NCT05720546
- Testing
- Baseline Survey, Semi-structured interviews, Follow-up Survey
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Aging, Pain, Acute
Effects of Acute Pain on Motor Learning in Young vs Older Adults
To date, the effects of pain on motor learning have not been thoroughly investigated, particularly in older adults. Broadly, the purpose of this research is to investigate the impact of acute pain on locomotor learning and its…
- Conditions
- Aging, Pain, Acute, Cognitive Decline, Motor Activity
- Trial name
- NCT05471557
- Testing
- pain delivery
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Influenza
Plasmablast Trafficking and Antibody Response in Influenza Vaccination (SLVP021 2011-2014)
The purpose of this study is to investigate the responses to licensed trivalent, inactivated influenza vaccine (TIV) delivered by different routes: intramuscular (IM) and intradermal (ID) and to the live, attenuated influenza…
- Trial name
- NCT02141581
- Testing
- Fluzone® (IM), Fluzone® Intradermal (ID), 2011-2012 FluMist®
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Stanford University
Recurrent High-grade Glioma
AsiDNA Children, Adolescents and Young Adults
HGG comprises diffuse midline gliomas (DMG), including diffuse infiltrating brainstem glioma (DIPG), characterised by histone gene mutations, as well as non-DM HGGs mainly in non-midline supratentorial areas, with distinct…
- Trial name
- AsiDNA (NCT05394558)
- Testing
- AsiDNA
- Where
- 10 sites in France
- Volunteers
- 8 people
- Sponsor
- Institut Curie
Balance; Distorted, Low Back Pain
Comparison of the Effectiveness of Two Different Squat Exercises in Healthy Individuals
The aim of our study is to compare the effects of two different squatting patterns, with and without the knees passing the toes, on low back pain, muscle strength and balance.
- Trial name
- NCT06843785
- Testing
- Squat with knees over toes, Squat where the knee does not pass the toes, control
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Bereavement
Long-term Consequences of Bereavement in Children, Adolescents and Young Adults
The purpose of this study is to examine how the death of a parent as a child, adolescent or young adult affects health and psychosocial wellbeing in adult life and to evaluate the impact in adult life of counseling to children…
- Trial name
- NCT01453699
- Where
- Denmark
- Volunteers
- 1,225,660 people, healthy volunteers welcome
- Sponsor
- Danish Cancer Society
Nicotine Addiction, Vaping
Acute Effects of Vaping Nicotine on Cognition in Young Adults
To examine reward processing and cognitive control both with and without the influence of vaporized nicotine in young adults with no history of cigarette use using EEG and fMRI.
- Trial name
- NCT04901208
- Testing
- Nicotine pod
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Yale University
Healthy Young Adult
Relationship Between Sleep Quality, Sleep Duration, Heart Rate, and Step Number
This study aims to evaluate the relationship among sleep duration, heart rate, number of steps, and sleep quality.
- Trial name
- NCT05829525
- Testing
- Evaluation of sleep quality, sleep duration, heart rate and step count
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Obesity
Motivational Interviewing for Weight Loss With Young Adults
This study is a 2-arm randomized controlled trial to evaluate the feasibility, acceptability and preliminary efficacy of an MI-based program for weight loss in young adults.
- Trial name
- LiveWellRVA (NCT01899625)
- Testing
- Brief Behavioral Weight Loss (BWL), Motivation Enhanced BWL
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Virginia Commonwealth University
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