Clinical trials: Young People
Migraine in Children, Migraine
A Study in Children and Young People With Migraine to Learn What the Body Does to Eptinezumab
The purpose of the study is to investigate how the body absorbs, distributes, and get rid of eptinezumab when given directly into a vein.
- Trial name
- NCT04537429
- Testing
- Eptinezumab
- Where
- 9 sites in United States
- Volunteers
- 28 people
- Sponsor
- H. Lundbeck A/S
Human Papillomavirus, Human Papillomavirus Infection
Human Papillomavirus in Young People Epidemiological Research 2 (HYPER2)
Australia was one of the countries to implement a universal school-based male vaccination program - in 2013. This research project will examine the prevalence of HPV among young men who have sex with men (MSM) who have been…
- Trial name
- HYPER2 (NCT03000933)
- Where
- Australia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Alfred
HIV
Project Engage: A Wrist Biosensor-based mHealth Suite to Support Alcohol Intervention in Young People Living With HIV
In this study, participants will be asked to wear a wrist alcohol biosensor for 30 days and report alcohol use using a ecological momentary assessment (EMA) app.
- Trial name
- SHARE Engage (NCT05431855)
- Testing
- eWrapper-Engagement strategies to facilitate alcohol biosensor wearing
- Where
- 3 sites in United States
- Volunteers
- 66 people
- Sponsor
- Florida State University
Self Harm
Occupational Therapy for Children and Young People Who Self-harm: A Qualitative Study
The goal of this qualitative observational study is to explore the experiences of children and their carers, receiving occupational therapy for self-harm and the experiences of health professionals delivering these interventions.
- Trial name
- NCT06317155
- Testing
- Occupational therapy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Functional Gastrointestinal Disorders, Gastroparesis
Validation of a Mental Health Scale for Young People With Chronic Stomach Symptoms
This study aims to validate the Alimetry® Gut-Brain Wellbeing Survey- Youth Version (AGBW-Y), a mental health scale developed for patients aged 12-17 years with chronic stomach symptoms.
- Conditions
- Functional Gastrointestinal Disorders, Gastroparesis, Vomiting; Cyclical, Nausea
- Trial name
- NCT06394154
- Volunteers
- 100 people
- Sponsor
- Greg O'Grady
Radio Dermatitis, Mucositis Oral
Using Red Light Therapy to Ease Skin Side Effects and Mouth Side Effects, in Children and Young People Aged 0 to 16 Years Old, Receiving Radiotherapy
The goal of this interventional study is to see if the daily use of red light therapy called photobiomodulation can help sore skin and sore mouths in children having radiotherapy.
- Conditions
- Radio Dermatitis, Mucositis Oral, Oesophagitis
- Trial name
- RADIANT (NCT07183267)
- Testing
- Photobiomodulation
- Where
- United Kingdom
- Volunteers
- 248 people
- Sponsor
- The Christie NHS Foundation Trust
Suicidal Ideation, Suicide, Attempted
Reducing Suicide Ideation Among Young People
It is Cluster Randomized Control Trial research to examine feasibility and relevance of the modified tool Nae Disha for Life, which will incorporate suicide prevention and resilience to reduce suicide ideation among young people…
- Trial name
- NCT06474312
- Testing
- Nae Disha
- Where
- India
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Asthma, Asthma in Children
Performance and Adherence in Children Using Spacers
Asthma is a common disease which causes swelling in the airways, making it difficult to breathe. Asthma is common in children, affecting 1 in 11 children in the UK. Asthma is treated with inhalers which reduce the swelling.
- Trial name
- OUTER-SPACERS (NCT05366309)
- Testing
- Tailored education, Standard care education
- Where
- United Kingdom
- Volunteers
- 43 people
- Sponsor
- University Hospitals of North Midlands NHS Trust
Children and Adolescents in Foster Care and Residential Care
Resilience for Children and Young People in Foster Care and Residential Care in Denmark
In this project we invite 9.000 children and young persons in Denmark and their foster parents and staff at the residential institutions to participate in a cluster randomized controlled intervention study where we aim to test…
- Trial name
- NCT02220179
- Testing
- The Resilience Program
- Where
- Denmark
- Volunteers
- 9,000 people
- Sponsor
- Poul Bak
Depression
OxSYPan: Oxford Study With Young People on Antidepressants
Fluoxetine is commonly used to treat adolescent depression, but the neural mechanisms underlying antidepressant drugs in the young brain are still poorly understood.
- Trial name
- OxSYPan (NCT03436173)
- Testing
- Fluoxetine, Peppermint syrup
- Volunteers
- 32 people
- Sponsor
- University of Oxford
Mental Health Impairment, Mental Health Disorder
The MILESTONE Study: Improving Transition From Child to Adult Mental Health Care
This study evaluates the longitudinal health and social outcomes of adolescent mental health service users who are at the transition boundary of their child and adolescent mental health service, and whether the implementation of…
- Trial name
- MILESTONE (NCT03013595)
- Testing
- TRAM feedback
- Where
- 10 sites in Belgium, Croatia and 6 more
- Volunteers
- 1,000 people
- Sponsor
- University of Warwick
Asthma Childhood, Exercise
Active Airways for Children and Young People With Asthma
What is this study about? The investigators want to see if exercise and education sessions can help children and young people (aged 10-17) with asthma, manage the participants asthma better.
- Conditions
- Asthma Childhood, Exercise, Children
- Trial name
- NCT07643753
- Testing
- EXERCISE TRAINING WITH OR WITHOUT MEDICATION, education
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Leicester
Rheumatic Diseases, Rheumatic Disorder
Exploring and Measuring the Impact of Steroids in Children and Young People
Assessing the impact of glucocorticoids in children and young people with rheumatic conditions, to develop a patient reported outcome measure (PROM).
- Conditions
- Rheumatic Diseases, Rheumatic Disorder, Rheumatologic Conditions (JRA,Lupus)
- Trial name
- NCT07350395
- Where
- 3 sites in United Kingdom
- Volunteers
- 70 people
- Sponsor
- University of the West of England
At Risk Mental State, Attenuated Psychotic Symptoms
The Feasibility of a Novel Intervention for At Risk Mental State
Young people with At Risk Mental State (ARMS) may have changes in their thoughts and the way they see or hear things, which they might find odd and distressing.
- Trial name
- NCT03160092
- Testing
- Intervention
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of East Anglia
Internet Addiction Disorder
Evaluation of a Therapeutic Education Application in the Treatment of Young People with Moderate or Problematic Screen Use
This single-center, controlled, and randomized study evaluates the effectiveness of the Phonix Care app in regulating screen use among young people aged 11 to 25.
- Trial name
- PHONIX CARE (NCT06648538)
- Testing
- Phonix Care
- Where
- France
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Psychosis, Schizoaffective Disorder
OnTrack>An Online Role-Playing Game for Young People With First Episode Psychosis
The research team will develop and test a prototype version of OnTrack>An Online Role-Playing Game (OnTrack>The Game or OTG), an online role-playing game designed for youth and young adults experiencing First Episode Psychosis…
- Conditions
- Psychosis, Schizoaffective Disorder, Schizophrenia
- Trial name
- NCT03390491
- Testing
- OnTrack>TheGame (OTG), Recovery Videos (RV)
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Center for Social Innovation, Massachusetts
Contact With or Exposure to Human Immunodeficiency Virus
ImPrEP LEN Brasil: Twice-Yearly Lenacapavir for HIV Prevention
The goal of this study is to learn how well long-acting lenacapavir works to prevent human immunodeficiency virus (HIV) infection in people at higher risk of getting HIV in Brazil.
- Trial name
- ImPrEP LEN (NCT07497594)
- Testing
- Lenacapavir long-acting, Tenofovi-Emtricitabine (TDF/FTC) tablet
- Where
- 8 sites in Brazil
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Oswaldo Cruz Foundation
HIV Infections
The Implementation of Pre-exposure Prophylaxis of Injectable Cabotegravir
Although CAB LA PrEP has been proven efficacious in blinded randomized controlled clinical trials, additional research is needed to evaluate effectiveness in real world settings as well as to identify effective implementation…
- Trial name
- ImPrepCab (NCT05515770)
- Testing
- Cabotegravir Injection
- Where
- Brazil
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Evandro Chagas National Institute of Infectious Disease
Mental Health Issue
The Effect of Increasing Physical Activity or Reducing Mobile Phone Use on Mental Health in Young People in Austria
Introduction: Data show adolescent mental health has declined in recent years, possibly due to increased uncertainty and loss of opportunities.
- Trial name
- SPARKY (NCT06153524)
- Testing
- Physical activity, Smartphone time
- Where
- Austria
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Danube University Krems
Depression, Anxiety
Identity-Based Transdiagnostic Therapy for Young People With Anxiety and Depression
Depression and anxiety are the most prevalent mental disorders among both the general population and young adults, and transdiagnostic treatments for these patients are mostly based on cognitive-behavioral therapy (CBT).
- Trial name
- IBTTYOUNG (NCT06384196)
- Testing
- Identity-Based Transdiagnostic Therapy (IBTT), Unified Protocol
- Where
- 2 sites in Spain
- Volunteers
- 138 people
- Sponsor
- University of Barcelona