Clinical trials: Zhejiang University
Cancer Pain
Development of a Cloud-Based PRO (Patient-Reported Outcome) Management Program for Home-Based Cancer Pain Care
This study aims to develop and pilot a cloud-based Patient-Reported Outcomes (PROs) management program for home-based cancer pain patients within a hospital setting.
- Trial name
- NCT07308223
- Testing
- Proactive monitoring and patient education
- Where
- China
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Postoperative Delirium
The Role of Remazolam in Reducing the Incidence of Postoperative Delirium in Elderly Patients
This study is a prospective, randomized, controlled trial.The selected patients were randomly divided into remazolam general anesthesia group and propofol + midazolam general anesthesia control group according to computer…
- Trial name
- NCT05466279
- Testing
- remazolam, Propofol, Midazolam
- Where
- China
- Volunteers
- 131 people
- Sponsor
- Fang Jun
Recurrent Pregnancy Loss
Establishment of Special Disease Cohort for RPLand Study of Impact Mechanism of Early Embryo Development
Recurrent pregnancy loss (RPL) is a refractory disease with diverse etiologies, complex pathogenesis and limited therapeutic options. Current tests and treatments lack uniform specifications.
- Trial name
- NCT05186207
- Testing
- abnormal pre-pregnancy test results that need clinical intervention
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Severe Periodontitis, Risk Factors
Risk Factors for Severe Periodontitis in 30 to 40 Year Olds: a Retrospective Study
Periodontitis is one of the most common oral diseases, which is characterized by alveolar bone resorption and destruction. In China, as a major country in the incidence of periodontitis, there is a huge population of patients…
- Conditions
- Severe Periodontitis, Risk Factors, Gene Polymorphism
- Trial name
- NCT04960774
- Testing
- Observational study, no intervention
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
pcTBS, Pain
Effects of Prolonged Continuous Theta Burst Stimulation on Pain and Neural Excitability
Numerous studies have confirmed the analgesic effect of M1-rTMS on both induced pain and various chronic pains and subsequently found that pcTBS is more time-efficient and can produce the same or even stronger analgesic effect…
- Trial name
- NCT05852067
- Testing
- pcTBS of M1
- Where
- China
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Norepinephrine, Post-induction Hypotension
Determination of the ED50 and ED95 of Prophylactic Norepinephrine Infusion for Preventing Post-induction Hypotension in Elderly Patients Undergoing Major Abdominal Surgery
The goal of this clinical trial is to determine the ED50 and ED95 of prophylactic norepinephrine infusion for preventing post-induction hypotension in elderly patients undergoing major abdominal surgery using up-and-down…
- Trial name
- NCT05637164
- Testing
- norepinephrine bitartrate
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Outcome
Factors Influencing the Prognosis of Olfactory Dysfunction After Upper Sensation
Objective: This study aimed to analyze the outcomes of post-infectious olfactory dysfunction treated with different doses of corticosteroids and specify factors related to the curative effect.
- Trial name
- NCT04918953
- Testing
- methylprednisolone, budesonide atomization suspension
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Non-suicidal Self-injury
Research on the Intervention of VR-based Emotion Regulation Technology on Adolescent Non-suicide Self-injury Behavior
Non suicidal self injury (NSSI) has become a serious social and public health problem allover the world, and the incidence rate is increasing year by year.
- Trial name
- VR (NCT05734872)
- Testing
- Virtual Reality Technology, Routine mental health course training
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pregnancy Complications
Comparative Effectiveness of Uterine Repair Surgery on Preventing Recurrence of Cesarean Sar Pregnancy
The goal of this observational study is to learn about the long-term effects of resection surgery which is cesarean scar pregnancy(CSP) excision plus hysterotomy closure in CSP patients to treat their CSP.
- Trial name
- CECS (NCT06485180)
- Testing
- Active comparator
- Where
- China
- Volunteers
- 606 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Surgery
Diagnosis and Treatment of Foreign Bodies Outside Pharynx and Esophagus Lumen
Objective: To improve the success rate of the treatment of migrating foreign bodies in the upper aerodigestive tract. Methods: The medical records of inpatients conforming to the diagnosis of migrating foreign bodies between 2020…
- Trial name
- NCT04917367
- Testing
- exploratory surgery
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Inflammatory Skin Disease
The Safety and Effectiveness of Local Injection of Antihistamines in Treatment of Inflammatory Skin Diseases
The treatment of chronic inflammatory skin diseases is a difficult point in clinical diseases, which mainly include patients with pathological scars, sarcoidosis and chronic eczema.
- Trial name
- NCT04937101
- Testing
- Chlorpheniramine-Codeine
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Aging
Large-scale Multi-omics Analysis of Cerebrospinal Fluid
The aim of this study is to explore the role of cerebrospinal fluid (CSF) biomarkers in aging and neurodegenerative diseases.
- Trial name
- NCT06636201
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Zhejiang University
The Impact of Fexofenadine Hydrochloride on the Prognosis of Patients Post-Acute Myocardial Infarction
The goal of this study is o evaluate the prognostic effect of fexofenadine hydrochloride in patients with myocardial infarction
- Trial name
- NCT07381803
- Testing
- Fexofenadine 60 Mg Oral Tablet
- Where
- China
- Volunteers
- 2,804 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Valvular Heart Disease
Valvular Heart Disease Registry Study in Second Affiliated Hospital of ZheJiang University
We design a prospective, observational cohort study to provide contemporary information on the prevalence, characteristics, risk stratification，cost-effective ,treatments and prognosis of Chinese hospitalised adult patients with…
- Trial name
- VHD-ZJU (NCT03011697)
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Urinary Incontinence, Pelvic Floor Muscle Training
Airbag-type Stretchable Electrode Array（ASEA） for Electrical Stimulation in Urinary Incontinence in Postmenopausal Women
The prevalence of urinary incontinence increases after the menopause and affects between 38 % and 55 % of women aged over 60 years. Urinary incontinence has a profound impact on quality of life.
- Trial name
- NCT05506124
- Testing
- airbag-type stretchable electrode array (ASEA) device, two-channel hard electrode device
- Where
- China
- Volunteers
- 58 people
- Sponsor
- Zhenwei Xie
Colorectal Cancer, Liver Metastasis
Compare Efficacy and Safety of Raltitrexed-based and 5fu-based Neoadjuvant Chemotherapy for Colorectal Liver Metastasis
This study is a multicenter ,randomization, open control study to evaluate the efficacy and safety of Raltitrexed-based chemotherapy and 5-fluorouracil-based chemotherapy in the peri-operative treatment of patients with Liver…
- Trial name
- NCT02453490
- Testing
- Raltitrexed-based chemotherapy, 5-fluorouracil-based chemotherapy
- Where
- 9 sites in China
- Volunteers
- 360 people
- Sponsor
- Zhejiang University
Chemotherapeutic Toxicity
Residual Neuromuscular Block of Rocuronium in Chemotherapy Patients Under Sevoflurane Anesthesia
Chemotherapy causes motor nerve dysfunction and degeneration that may alter the response to neuromuscular blocking drugs. To analyse the risk of residual neuromuscular block (RNMB) induced by rocuronium given in standard doses to…
- Trial name
- NCT04965532
- Testing
- sevoflurane anesthesia, Propofol Injection
- Where
- 2 sites in China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Gastric Cancer, Precancerous Lesion
Nasal Endoscopic Screening and Risk Assessment for Early Gastric Cancer
Pepsinogens (PGs) can be used for gastric cancer (GC) screening, but the cutoff levels vary among studies, and PG levels are influenced by numerous factors.
- Conditions
- Gastric Cancer, Precancerous Lesion, Helicobacter Pylori Infection
- Trial name
- NCT04989153
- Testing
- pepsinogen
- Where
- 9 sites in China
- Volunteers
- 5,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Periodontitis
Study on the Relationship Between Periodontitis and Renal Disease
Analysis of inflammatory markers in periodontitis and patients with early and middle stage renal disease.
- Trial name
- NCT02417363
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Gestational Trophoblastic Tumor, Effects of Chemotherapy
Combination of Methotrexate(MTX) and Actinomycin(ACTD) in the Low Risk Gestational Trophoblastic Neoplasma （GTN） Patients With Score of 5-6
In this study, a prospective, multicenter randomized controlled study was conducted to compare the clinical efficacy and toxicity response of combination MTX+ACTD multi-course regimen in low-risk GTN patients with score 5-6 with…
- Conditions
- Gestational Trophoblastic Tumor, Effects of Chemotherapy, Drug Toxicity
- Trial name
- NCT03885388
- Testing
- MTX, MTX+ACTD
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University