Clinical trials: Zinc Deficiency
Dietary Selenium Deficiency, Dietary Zinc Deficiency
Zinc and Selenium Supplementation in Atherosclerosis
The aim of this randomized double-blind study was to evaluate the effect of oral zinc and selenium supplementation on oxidative stress and inflammation biomarkers as well as the status of zinc and selenium in patients with…
- Trial name
- NCT01547377
- Testing
- zinc and selenium supplementation
- Where
- Brazil
- Volunteers
- 76 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Zinc Deficiency
Impact of Mass Zinc Fortification Programs on Plasma Zinc Concentration
The purpose of the study is to evaluate the use of plasma zinc concentration for assessing the impact of mass zinc fortification programs.
- Trial name
- NCT00944723
- Testing
- Zinc-fortified bread, Zinc supplement, Non-fortified bread
- Where
- Senegal
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Zinc Deficiency
Zinc and the Synthesis of Zinc Binding Proteins (Protocol B)
The specific aim of this protocol is to examine differential expression of specific mRNAs and proteins that occur when the dietary intake of zinc is acutely reduced below the dietary requirement for a period of ten days.
- Trial name
- NCT01221129
- Testing
- Acclimation, Dietary zinc depletion, Dietary zinc repletion
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Florida
Zinc Deficiency
Dose Adjustment Study of NPC-02 in Patients With Zinc Deficiency
The objective of this study is to check the dose control method of NPC-02 and the holding effect for the target serum zinc concentration in patients with zinc deficiency.
- Trial name
- NCT02321865
- Testing
- NPC-02
- Where
- Japan
- Volunteers
- 43 people
- Sponsor
- Nobelpharma
Environmental Enteric Dysfunction, Zinc Deficiency
Effects of EED on Zn Absorption and Retention in Children From a Standard Dose
The overall objective is to determine the impact of EED on zinc absorption and homeostasis, and its impact on the absorptive capacity of vitamin A absorption of young children (18-24 months of age) in an austere setting with high…
- Conditions
- Environmental Enteric Dysfunction, Zinc Deficiency, Vitamin A Deficiency
- Trial name
- ZEED1 (NCT02760095)
- Testing
- 3 mg zinc sulfate supplement, 0.5 mg of 13C10-retinyl-acetate
- Where
- 2 sites in United States, Bangladesh
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Weight Gain, Anemia, Iron Deficiency
Egg Intervention During Pregnancy in Indonesia
The study consists of two arms: 1) intervention group using eggs as supplementary food given from 2nd trimester of pregnancy to birth, and 2) observational group of pregnant mothers.
- Conditions
- Weight Gain, Anemia, Iron Deficiency, Birth Weight, Birth Length
- Trial name
- PRECODE (NCT04694235)
- Testing
- Egg intervention
- Where
- Indonesia
- Volunteers
- 702 people, healthy volunteers welcome
- Sponsor
- SEAMEO Regional Centre for Food and Nutrition
Zinc Deficiency
Water-based Zinc Efficacy Trial in Beninese Shool Children
The general objective of this study is to determine the effect of the daily consumption of zinc-fortified water provided by the LSF-filter on zinc status and diarrhea rates in school age children from rural areas characterized by…
- Trial name
- NCT01790321
- Testing
- LSF-filtering device
- Where
- Benin
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Prof. Michael B. Zimmermann
HIV-infection/Aids, Malnutrition
Impact of RUTF on Body Composition, Anemia and Zinc Status of PLWHA
A clinical trial was conducted in 65 PLWH randomly allocated to receive standard hospital diet alone (Control group: n=33), or the diet combined with 100 g/day of RUTF (RUTF group: n=32).
- Trial name
- PLWHA (NCT02433743)
- Testing
- Ready-to-use therapeutic food (RUTF)
- Where
- Senegal
- Volunteers
- 65 people
- Sponsor
- Cheikh Anta Diop University, Senegal
Anemia, Iron-Deficiency
Non-invasive Optical Detection of Iron Deficiency
This study aims to evaluate a prototype device detecting zinc protoporphyrin-IX fluorescence non-invasively from the intact oral mucosa. Zinc protoporphyrin-IX is an established indicator of iron deficiency.
- Trial name
- NCT02310607
- Testing
- Not an interventional study
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- Klinikum der Universitaet Muenchen, Grosshadern
Vitamin A Deficiency, Iron Deficiency
An Efficacy Trial of Iron, Zinc and Vitamin A Fortified Rice in Children in Satun, Thailand
Iron, zinc and vitamin A deficiencies are particularly common among children and young women in the developing countries of South and Southeast Asia resulting in important adverse health effects.
- Conditions
- Vitamin A Deficiency, Iron Deficiency, Zinc Deficiency
- Trial name
- NCT01061307
- Testing
- fortified extruded rice
- Where
- 2 sites in Switzerland, Thailand
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency Anemia, Infectious Diseases
Efficacy Trial to Examine Efficacy of Multimicronutrient Home Supplementation in Infants
The objective of the program is to examine the efficacy of 6 month home micronutrient supplementation in Bedouin and Jewish children on improvements in nutritional status including measures of iron, ferritin, zinc and folic acid…
- Conditions
- Iron Deficiency Anemia, Infectious Diseases, Undernutrition
- Trial name
- NCT00276198
- Testing
- Sprinkles, Ferripel-3, Vitamins A&D drops
- Where
- Israel
- Volunteers
- 771 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Iron Deficiency
Iron Bioavailability From Encapsulated Ferrous Sulphate
Salt is one of the very few regularly purchased food item in all socioeconomic classes including poor remote areas with subsistence farming.
- Trial name
- NCT02353325
- Testing
- non-encapsulated FeSO4, encapsulated FeSO4, before cooking, encapsulated FeSO4, after cooking
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
HIV, HIV Infections
Autologous T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases SB-728 for HIV
This research study is being carried out to study a new way to possibly treat HIV. This agent is called a "Zinc Finger Nuclease" or ZFN for short. ZFNs are proteins that can delete another protein named CCR5.
- Trial name
- Zinc-Finger (NCT00842634)
- Testing
- ZFN modified T cells, Structured Treatment Interruption
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of Pennsylvania
Celiac Disease, Nutrient Deficiency
Zinc Deficiency Treatment in Celiac Disease: Supplementation Versus Diet
Micronutrient deficiencies are common amongst celiac disease (CeD) patients due to consumption of a restrictive and nutritionally unbalanced gluten-free diet (GFD) in addition to slow intestinal villi healing.
- Trial name
- NCT05782257
- Testing
- Zinc Supplementation, Zn-Optimized Diet
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McMaster University
Zinc Deficiency, Dyslipidemias
Zinc Supplement Before or With Food in Generally Healthy Men
The purpose of this study is to determine the influence of food consumption timing on the body's response to a zinc supplement
- Conditions
- Zinc Deficiency, Dyslipidemias, Zinc Excess, Inflammation
- Trial name
- NCT03619421
- Testing
- Zinc supplement
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Very Low Birth Weight Infant, Nutritional Deficiency
Enteral Zinc Supplementation in Very Low Birth Weight Infants
The goal of this clinical trial is to observe for changes in rate of weight gain in the very low birth weight (VLBW) infants by adding an enteral Zinc supplement of 1 mg/kg/day of elemental zinc.
- Trial name
- NCT06433674
- Testing
- Zinc Sulfate, Sterile Water
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Poliomyelitis
Effect of Zinc Supplementation on Response to Oral Polio Vaccine in Infants in Pakistan
Pakistan is one of the 4 developing countries where cases of poliomyelitis are still being identified. Despite the incessant efforts by WHO and UNICEF, this disease is far from control.
- Trial name
- NCT01229579
- Testing
- Zinc Sulfate
- Where
- Pakistan
- Volunteers
- 320 people
- Sponsor
- Aga Khan University
HIV, Zinc Status
Zn Supplementation in HIV Immunological Non Responders
Zinc is an essential micronutrient crucial for the normal functioning of the human immune system. Zinc deficiency impairs immune function and increases infection risk, especially in vulnerable populations like people living with…
- Conditions
- HIV, Zinc Status, HIV Infection
- Trial name
- VIHZn (NCT06612554)
- Testing
- zinc acetate
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Parc de Salut Mar
Human Immunodeficiency Virus (HIV)
A Phase I Study of T-Cells Genetically Modified at the CCR5 Gene by Zinc Finger Nucleases SB-728mR in HIV-Infected Patients
This is a triple cohort, open-label pilot study of the safety and antiviral activity of a single infusion of autologous CD4+ T cells genetically modified at the CCR5 gene by Zinc Finger Nucleases SB-728mR (ZFN Modified CD4+ T…
- Trial name
- NCT02388594
- Testing
- ZFN Modified CD4+ T Cells, Cyclophosphamide
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Pennsylvania
HIV Infection
Atazanavir/Ritonavir and Zinc Pharmacokinetic Study
The study is being conducted as the most common side effect of the HIV drug atazanavir (taken with ritonavir) is hyperbilirubinaemia.
- Trial name
- SSAT043 (NCT01475227)
- Testing
- 1 Solvazinc tablet, day 2 to day 15, 1 Solvazinc tablet, day 15 to day 28
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- St Stephens Aids Trust