Clinical trials: a Randomized Controlled Trial
AIDS
Mesenchymal Stem Cells Treatment for AIDS Patients at Late Stage
The goal of this study is to conduct a prospective, double-blind, randomized placebo-controlled clinical trial to investigate the safety and efficacy of mesenchymal stem cells treatment for AIDS patients at late stage.
- Trial name
- NCT05939167
- Testing
- mesenchymal stem cell, saline
- Where
- 4 sites in China
- Volunteers
- 150 people
- Sponsor
- Cell Energy Life Sciences Group Co. LTD
Polycystic Ovary Syndrome
Comparison Between Two Different Protocols in Polycystic Ovary Symdrome Women Undergoing Intra-cytoplasmic Injection
Stein and Leventhal were the first to recognize an association between the presence of polycystic ovaries and signs of hirsutism and amenorrhea (eg,oligomenorrhea, obesity), After women diagnosed with Stein-Leventhal syndrome…
- Trial name
- NCT04094467
- Testing
- Cetrorelix, Leuprolide Acetate
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Assiut University
Major Depressive Disorder, Suicide
i-CBT and IV Ketamine for Suicidality in Treatment-Resistant Depression: A Randomized, Midazolam-Controlled Clinical Trial
Approximately four thousand Canadians die by suicide every year, and suicide is the second leading cause of death in youth and young adults (15-34 years).
- Conditions
- Major Depressive Disorder, Suicide, Treatment Resistant Depression
- Trial name
- Ket-CBT (NCT06480500)
- Testing
- Ketamine hydrochloride, i-CBT (Internet-based Cognitive Behavioural Therapy), Midazolam Hydrochloride
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- University Health Network, Toronto
Frailty, Thoracic Surgery
A Frailty-specific Prehabilitation Program for Mild to Moderately Frail Patients Undergoing Cardiac Surgeries/Procedures
The purpose of this study is to investigate the effects of the frailty-specific prehabilitation program on functional capacity, frailty, cardiac-specific functional status, serum albumin level, high-sensitivity C-reactive protein…
- Trial name
- NCT07824700
- Testing
- Frailty-specific prehabilitation program
- Where
- Hong Kong
- Volunteers
- 144 people
- Sponsor
- The University of Hong Kong
ADL
Effect of Intensified Occupational Therapy on Basic Activities of Daily Living
The objective is to investigate the effect of an intensified occupational therapy intervention on independence in basic activities of daily living (ADL) in subjects with stroke
- Trial name
- NCT05638607
- Testing
- Intensified occupational therapy
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Aarhus
Post COVID-19
A Telemedicine Brief Mindfulness Intervention in Post-COVID-19
Background: Several studies suggest that SARS survivors still presented with high levels of psychological distress overall at 1, 3, 12, and 18 months after hospital discharge.
- Trial name
- NCT05175807
- Testing
- Mindfulness
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Health Knowledge, Attitudes, Practice
Impact of the Financial Inclusion Improves Sanitation and Health
The goal of this interventional study is to evaluate the impacts of Financial Inclusion improvement sanitation and Health (FINISH) interventions in Kenya's Homa Bay County and Uganda's Kamwenge District among children under five.
- Trial name
- FINISH (NCT06356636)
- Testing
- Financial Inclusion Improves Sanitation and Health
- Where
- Kenya
- Volunteers
- 1,090 people, healthy volunteers welcome
- Sponsor
- Amref Health Africa
Anxiety, Depression
Managing Anxiety From Cancer (MAC): Testing an Intervention for Anxiety in Older Adults With Cancer and Their Caregivers
This study is being done to test the effects of Managing Anxiety from Cancer (MAC) therapy on anxiety compared to usual care, in patients and their caregivers.
- Conditions
- Anxiety, Depression, Quality of Life
- Trial name
- NCT03168971
- Testing
- Managing Anxiety from Cancer (MAC)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Patient Depression, Anxiety, Stress and Pain
The Effect of Listening to Holy Quran Recital on Depression, Anxiety and Stress Post CABG
Coronary artery bypass graft (CABG) is one of the most common surgical treatments for coronary artery disease. CABG has many beneficial outcomes for patients.
- Trial name
- NCT05419544
- Testing
- Holy Quran Recital effect
- Where
- 2 sites in Jordan
- Volunteers
- 128 people
- Sponsor
- Applied Science Private University
Dry Eye Disease
A Clinical Trial to Assess the Safety and Efficacy of Subjects With Dry Eye Disease
A Multicenter, Phase 3, Randomized, Double-Masked, Parallel-Group, Vehicle-Controlled, Environment Exposure Clinical Trial to Assess the Efficacy and Safety of 0.25% Reproxalap
- Trial name
- NCT06424444
- Testing
- Reproxalap ophthalmic solution (0.25%), Vehicle ophthalmic solution
- Where
- United States
- Volunteers
- 421 people
- Sponsor
- Aldeyra Therapeutics, Inc.
Allergic Conjunctivitis
The INVIGORATE Trial: A Clinical Trial to Assess the Efficacy and Safety of Subjects With Seasonal Allergic Conjunctivitis.
The INVIGORATE Trial: A Randomized, Double-masked, Crossover Design, Phase 3 Clinical Trial to Assess the Efficacy and Safety of Subjects With Seasonal Allergic Conjunctivitis.
- Trial name
- NCT04207736
- Testing
- Reproxalap Ophthalmic Solution (0.25%), Vehicle Ophthalmic Solution
- Where
- Canada
- Volunteers
- 95 people
- Sponsor
- Aldeyra Therapeutics, Inc.
Tension Headache
The Effectiveness of Pharmacopuncture on Acute Tension Headache
This study is a double blind, randomized controlled trail. condition/disease: acute tension headache treatment/intervention: Pharmacopuncture
- Trial name
- NCT05549765
- Testing
- Pharmacopuncture, Korean medical treatment
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Jaseng Medical Foundation
Adrenal Suppression, Hemodynamic Instability
THe Comparison of Target Controlled Infusion of Propofol or Etomidate at General Anesthesia in Geriatric Patients
Compare the efficacy and safety of closed-loop target controlled infusion of propofol or etomidate at general anesthesia in geriatric patients
- Trial name
- NCT02111265
- Testing
- Remifentanil, Cisatracurium, Sufentanil
- Volunteers
- 90 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Compare Operational Performance of Three Technology in Lung Models
The Assessment of the Feasibility and Operational Performance of Automated System Bronchoscopy in a Simulated Environment
Recruit 30 trainee physicians from 6 centers and compare their performance in operating lung models using automatic bronchoscopy, robotic bronchoscopy, and electromagnetic navigation bronchoscopy.
- Trial name
- NCT06741267
- Testing
- RBS, AB, ENB
- Where
- Chad
- Volunteers
- 30 people
- Sponsor
- Guangzhou Medical University
Pilonidal Sinus, Pilonidal Disease
The Role of Mesenchymal Stem Cell and Exosome in Treating Pilonidal Sinus Disease in Children
Chronic wounds that fail to heal over extended periods pose a significant financial burden on the healthcare system, underscoring the urgent need to enhance clinical treatments.
- Trial name
- NCT06391307
- Testing
- Crystallized phenol, Crystallized phenol + Exosome, Crystallized phenol + Stem Cell
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Mustafa Azizoğlu
HIV Infections
TOTEM: Switch From Other Nucleoside Reverse Transcriptase Inhibitors (NRTIs) to Once Daily Truvada
This study looked at lipid changes in human immunodeficiency virus type 1 (HIV-1) infected patients when the nucleoside reverse transcriptase inhibitors (NRTIs) in their existing highly active antiretroviral therapy (HAART)…
- Trial name
- TOTEM (NCT00323492)
- Testing
- Truvada, Current HAART regimen
- Where
- France
- Volunteers
- 92 people
- Sponsor
- Gilead Sciences
Delivery of Health Care
Financial Incentives for Care Gaps
This project seeks to understand how individuals respond to financial incentive programs for wellness care. In a randomized controlled trial among customers with care gaps, the investigators will experimentally compare the…
- Trial name
- NCT03715907
- Testing
- Financial Incentives, Information
- Where
- United States
- Volunteers
- 8,042 people, healthy volunteers welcome
- Sponsor
- Massachusetts Institute of Technology
Knee Osteoarthritis
Effect of Antigravity Treadmill in Knee Osteoarthritis (AGTreadmill)
To date, the anti-gravity treadmill, as a representative method of lower body positive pressure treadmills, has been rarely reported for knee osteoarthritis rehabilitation.
- Trial name
- AGTreadmill (NCT06347692)
- Testing
- antigravity treadmill, physical therapy exercise program
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Prince Sattam Bin Abdulaziz University
Infantile Spasms
Short-term Ketogenic Diet as Compared With Conventional Long-term Trial in Refractory Infantile Spasms: A Randomized, Controlled Study
This is a randomized, controlled study to compare Short-term ketogenic diet with conventional long-term trial in refractory infantile spasms.
- Trial name
- NCT00968136
- Sponsor
- Yonsei University
Bradycardia
Brad Arrhythmia Induced by Repeated Succinylcholine During Gynecological Laparoscopic Surgery
Cardiac arrhythmias are a well-recognized complication of anesthesia for laparoscopy. The aim of this study was to evaluate the efficacy of atropine sulfate for prevention of brad arrhythmia induced by repeated succinylcholine…
- Trial name
- NCT02676011
- Testing
- IM atropine, IV atropine, Atropine mixed with second dose succinylcholine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Assiut University
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