Clinical trials: acne
Acne
Management of Side-Effects of Anti-Acne Treatment by a Cosmetic Routine
Retinoid-based topical acne treatment may induce local tolerance issues such as erythema, dryness, stinging and burning sensations that may reduce adherence and efficacy.
- Trial name
- NCT05486910
- Where
- Poland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Acne Vulgaris
A Safety, Tolerability and Preliminary Efficacy Study of DRM01B Topical Gel
This is a Phase 1/2a study. The purpose of Phase 1 was to evaluate the safety and tolerability of DRM01B Topical Gel in 6 healthy volunteers.
- Trial name
- NCT01936324
- Testing
- Olumacostat Glasaretil Gel, 7.5%, Olumacostat Glasaretil Gel, Vehicle
- Where
- 12 sites in Canada
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Dermira, Inc.
Acne
Efficacy and Safety of CD5024 1% in Acne Vulgaris
Exploratory, multi-center, randomised, investigator-blinded, vehicle controlled study using intra-individual comparison involving subjects with acne vulgaris on face to evaluate the efficacy of CD5024 1% cream over a 6-week…
- Trial name
- NCT03034460
- Testing
- CD5024 1% cream, CD0271/CD1579 gel
- Where
- 7 sites in Canada, France and 1 more
- Volunteers
- 70 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Evaluation of Irritation That Potentially Could be Caused by Two Facial Gels Applied to Opposite Sides of the Face
A study to compare the skin irritation potential of two marketed gels for acne treatment, each applied to half of the face of healthy volunteers.
- Trial name
- NCT00952523
- Testing
- Tretinoin Facial Gel, Adapalene/Benzoyl Peroxide Facial Gel
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Acne Vulgaris
Study STF115287, a Clinical Confirmation Study of GSK2585823 in the Treatment of Acne Vulgaris in Japanese Subjects
This is a multicenter, randomized, single-blinded (investigator's blinded), active-controlled (clindamycin [CLDM] 1% gel), parallel-group study in Japanese subjects with acne vulgaris to demonstrate the efficacy of GSK2585823…
- Trial name
- NCT01445301
- Testing
- GSK2585823(CLDM 1%-BPO 3% gel), CLDM 1% gel twice daily
- Where
- 26 sites in Japan
- Volunteers
- 800 people
- Sponsor
- GlaxoSmithKline
Acne Vulgaris
Placebo Controlled Efficacy and Safety Study of CD2475/101 40 mg Tablets vs. Placebo and Doxycycline 100 mg Capsules Once Daily in the Treatment of Inflammatory Lesions of Acne Vulgaris
The primary objectives of the study is to show CD2475/101 40mg tablets taken once a day for 16 weeks is superior to the placebo in Change from baseline to Week 16(Last Observation Carry Forward, Intent To Treat) in inflammatory…
- Trial name
- NCT01320033
- Testing
- CD2475/101 40 mg, Doxycycline 100 mg
- Where
- 31 sites in United States
- Volunteers
- 662 people
- Sponsor
- Galderma R&D
Hidradenitis Suppurativa
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa
The purpose of the study is to evaluate the efficacy and safety of bimekizumab in study participants with moderate to severe hidradenitis suppurativa (HS)
- Trial name
- BE HEARD II (NCT04242498)
- Testing
- Bimekizumab
- Where
- 91 sites in United States, Australia and 12 more
- Volunteers
- 509 people
- Sponsor
- UCB Biopharma SRL
Acne
A Comparative Study of Cosmetic Product in Subjects With Facial Acne During an Associated-treatment Phase Followed by a Maintenance Phase
In this study, we are interested in the global benefit of the tested product as complementary care to a topical medical treatment during a 3 month-associated treatment phase followed by a 3 month-maintenance phase, compared to a…
- Trial name
- NCT06716398
- Testing
- Test product, Comparator product
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
NODULOCYSTIC ACNE
Finasteride Treatment of Severe Nodulocystic Acne
Double-blind, randomized, placebo-controlled, dose-ranging study to evaluate the efficacy and safety of once weekly, high dose oral finasteride compared to placebo for the treatment of severe nodulocystic acne in male subjects.
- Trial name
- NCT02502669
- Testing
- Finasteride 23.5 mg tablets, Finasteride 33.5 mg tablets
- Where
- 25 sites in United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Elorac, Inc.
Acne Vulgaris
Benzac 5% Gel in Combination With Cosmetic Products in Acne Vulgaris
The aim of this study is to evaluate a complete acne regimen consisting of a medication (Benzaknen® 5% Gel), and 2 cosmetic products Dermotivin® Soft Liquid soap and Cetaphil® Dermacontrol Moisturizer SPF30 in patients with acne.
- Trial name
- Benzac (NCT02589405)
- Testing
- Benzoyl Peroxide, Dermotivin® Soft Liquid cleanser, Cetaphil® Dermacontrol Moisturizer SPF30
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Clinical Endpoint Bioequivalence Study of Adapalene Gel 0.1%
To evaluate the therapeutic equivalence of topical Adapalene Gel, 0.1 % and Differin®(Adapalene) Gel, 0.1 % in the treatment of acne vulgaris and to demonstrate the superiority of the efficacy of the test and reference products…
- Trial name
- NCT04329403
- Testing
- Adapalene 0.1% Gel, Differin 0.1% Topical Gel
- Sponsor
- Aurobindo Pharma Ltd
Acne Scars
Laser Treatment of Acne Scars in Fitzpatrick Skin Types III-VI
The purpose of this study is to evaluate the RevLite Q-Switched Neodymium: Yttrium-Aluminum-Garnet (Nd:YAG) Laser in the treatment of acne scars in darker skin types (Fitzpatrick Skin Types III, IV, V and VI).
- Trial name
- NCT01221922
- Testing
- RevLite Q-Switched Nd:YAG Laser
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- ConBio, a Cynosure Company
Acne Vulgaris
BLI1100 for the Treatment of Moderate to Severe Acne Vulgaris
The purpose of this study is to compare the safety and efficacy of formulation BLI1100 to its vehicle in the treatment of moderate-severe acne vulgaris.
- Trial name
- NCT01241331
- Testing
- BLI1100, Vehicle cream
- Where
- 20 sites in United States
- Volunteers
- 233 people
- Sponsor
- Braintree Laboratories
Acne Vulgaris
A Clinical Study Evaluating the Safety and Efficacy of IDP-110 in Patients With Acne Vulgaris
The purpose of this study is to assess the effectiveness of IDP-110 in treating patients with acne vulgaris.
- Trial name
- NCT00664248
- Testing
- IDP-110, Clindamycin, Benzoyl peroxide
- Where
- 35 sites in United States, Belize and 1 more
- Volunteers
- 1,414 people
- Sponsor
- Dow Pharmaceutical Sciences
Acne
Comparison Study of Topical Acne Regimens
The purpose of this study is to compare the effectiveness of two over the counter acne products in subjects with moderate severity acne vulgaris.
- Trial name
- NCT00913185
- Testing
- Acne Free, Proactiv
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- MedDerm Associates
Acne Vulgaris
A Double Blind, Placebo-Controlled, Randomized Study in Subjects With Acne Vulgaris
This is a single center, randomized, double-blind, placebo-controlled study in subjects with acne vulgaris.
- Trial name
- NCT02656485
- Testing
- B244
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- AOBiome LLC
Acne Vulgaris
Acne Treatment With Active Oplon's Patches - 15-18 Years Old
The purpose of this study was to demonstrate the effect of short treatment with active OPLON patches on Acne.
- Trial name
- NCT01260766
- Testing
- Oplon Active Patch
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Oplon-Pure Science Ltd.
Wrinkle, Fine Lines
Feasibility Study to Collect and Assess Safety Data for a Radiofrequency Microneedling Device for Electrocoagulation and Hemostasis of Soft Tissues for Dermatologic Conditions
The goal of the Potenza device used in this study is to collect clinical data for dermatologic conditions in which electrocoagulation and hemostasis is a viable mechanism for means of improvement.
- Conditions
- Wrinkle, Fine Lines, Crepey Skin, Acne Scars
- Trial name
- NCT05987319
- Testing
- RadioFrequency Microneedling Device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cynosure, Inc.
Acne Vulgaris
A Study to Demonstrate the Efficacy and Safety of Adapalene/Benzoyl Peroxide Topical Gel in Subjects With Acne Vulgaris
This is a multi-center, randomized, double-blind, parallel group study with 12 weeks of treatment of acne vulgaris. Efficacy and safety evaluations will be performed at Screening (safety only), Baseline and Weeks 1, 2, 4, 8 and…
- Trial name
- NCT00421993
- Testing
- Adapalene/Benzoyl Peroxide, Adapalene, Benzoyl Peroxide
- Where
- 62 sites in United States, Canada and 3 more
- Volunteers
- 1,670 people
- Sponsor
- Galderma R&D
Acne
Comparative Efficacy and Safety of Benzoyl Peroxide Used in Combination With Clindamycin vs. Benzoyl Peroxide Used in Combination With Clindamycin and Doxycycline in the Treatment of Moderate Acne
To compare the efficacy and safety of Benzoyl peroxide used in combination with clindamycin vs. Benzoyl peroxide used in combination with clindamycin and doxycycline in the treatment of moderate acne
- Trial name
- NCT00837213
- Testing
- Benzoyl peroxide with clindamycin, Benzoyl peroxide with clindamycin and doxycycline
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- Stiefel, a GSK Company