Clinical trials: acne
Atrophic Acne Scars
Pilot Study of Combination Treatment With Subcision, Human Adipose Tissue-Derived Exosomes and Powdered Polydioxanone for Atrophic Acne Scars
This pilot study compared two treatments for depressed acne scars: subcision alone and subcision followed by injections containing exosomes derived from human fat-derived stem cells and powdered polydioxanone (PDO).
- Trial name
- NCT07914322
- Testing
- Subcision, Human Adipose-Derived Stem Cell Exosomes and Powdered Polydioxanone
- Where
- Malaysia
- Volunteers
- 12 people
- Sponsor
- COSMEDICIAN AP SDN BHD
Acne, Atopic Dermatitis
Use of the SpiderMass for in Vivo Analysis of the Skin in Five Chronic Inflammatory Dermatosis
The physiological states of the skin are characterized by a certain homeostasis linked to the balance of the metabolic pathways. When these pathways are deregulated, the proteic, lipidic and metabolic is affected.
- Conditions
- Acne, Atopic Dermatitis, Psoriasis Vulgaris, Rosacea
- Trial name
- NCT04472546
- Testing
- in-vivo mesure, Scotch, Lipid index
- Where
- France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Acne Vulgaris
A Multi-Center Open-Label Evaluation of the Safety of Sarecycline Tablets in the Treatment of Acne Vulgaris
Open-label study will evaluate the safety of an approximate 1.5 mg/kg/day dose of oral sarecycline in the long-term treatment of participants with moderate to severe facial acne vulgaris.
- Trial name
- NCT02413346
- Testing
- Sarecycline
- Where
- 56 sites in United States
- Volunteers
- 490 people
- Sponsor
- Almirall, S.A.
Acne Vulgaris
A Phase 2, Multicenter, Randomized, Double-Blind, Vehicle Controlled, Parallel-Group, Clinical Study in the Treatment of Acne Vulgaris
A Phase 2, Multicenter, Randomized, Double-Blind, Vehicle Controlled, Parallel-Group, Clinical Study in the Treatment of Acne Vulgaris
- Trial name
- NCT03170388
- Testing
- IDP-126 Gel, IDP-126 Component A, IDP-126 Component B
- Where
- 34 sites in United States, Canada
- Volunteers
- 741 people
- Sponsor
- Bausch Health Americas, Inc.
Acne Vulgaris
Open Label Photo-Documentation Study Of BPX-01 Minocycline Gel
This is a multi center open label study intended to provide photo documentation and time to response data for BPX-01 1 and 2% minocycline topical gel for the treatment of moderate to severe non-nodular inflammatory acne vulgarism.
- Trial name
- NCT02946788
- Testing
- Minocycline
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- BioPharmX, Inc.
Acne
Compound Adapalene and Clindamycin Hydrochloride Gel in Treatment of Patients With Acne
evaluate the safety and efficacy of Compound Adapalene and Clindamycin Hydrochloride Gel in treatment of chinese patients with acne.
- Trial name
- NCT02593383
- Testing
- Adapalene + Clindamycin Hydrochloride
- Where
- China
- Volunteers
- 245 people
- Sponsor
- Lee's Pharmaceutical Limited
Acne Vulgaris
A Safety and Efficacy Evaluation of Topical Treatments for Moderate-Severe Facial Acne Vulgaris
The objective of the study is to compare the safety and efficacy of multiple formulations of BLI1100 to a control group and placebo in treating patients with moderate-severe acne vulgaris.
- Trial name
- NCT02604680
- Testing
- BLI1100-1, BLI1100-2, BLI1100-3
- Where
- 50 sites in United States
- Volunteers
- 509 people
- Sponsor
- Braintree Laboratories
Acne Scars, Acne Scars - Atrophic
Safety and Efficacy Evaluation of the Radiofrequency Therapeutic Device for the Treatment of Atrophic Acne Scars
The objective of this clinical trial is to evaluate the safety and effectiveness of a radiofrequency treatment device for the treatment of atrophic acne scars.
- Conditions
- Acne Scars, Acne Scars - Atrophic, Acne Scar, Acne Scarring
- Trial name
- NCT07620769
- Testing
- Investigational Device with the function deactivated, Investigational Device with the function activated, Control Device
- Where
- 4 sites in China
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- CLASSYS Inc.
Acne
Topical ASC-J9 Cream for Acne
To evaluate the safety and efficacy of topical 0.1% and 0.025% ASC-J9 creams applied twice daily for facial acne compared to vehicle control.
- Trial name
- NCT01289574
- Testing
- ASC-J9
- Where
- 7 sites in United States, Taiwan
- Volunteers
- 181 people
- Sponsor
- AndroScience Corp
Acne Vulgaris
Comparison of Duac® Gel And Differin® Gel in Mild to Moderate Acne Vulgaris
Comparing the efficacy and safety of a gel formulation containing a combination of clindamycin phosphate (equivalent to 1% clindamycin) and benzoyl peroxide (5%) once daily with a gel containing 0.1% adapalene once daily in the…
- Trial name
- NCT00160394
- Testing
- Duac® Gel / Differin® Gel
- Where
- 3 sites in Poland, United Kingdom
- Volunteers
- 130 people
- Sponsor
- Stiefel, a GSK Company
Acne Scars - Mixed Atrophic and Hypertrophic
The MIRIA Acne Scar Study
This study is being conducted to evaluate the performance and efficacy of the AVAVA MIRIA Laser Skin System treatment on acne scars.
- Trial name
- MIRIA (NCT05597267)
- Testing
- MIRIA Laser
- Where
- 3 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- AVAVA, Inc.
Acne Vulgaris
Split-face Tolerability Comparison Between Adapalene-Benzoyl Peroxide Gel Versus Tretinoin Gel
To compare the tolerability of Epiduo® (adapalene and benzoyl peroxide) Gel 0.1%/2.5% to Retin-A Micro® (tretinoin gel) microsphere when used by subjects with acne vulgaris for 3 weeks in terms of local tolerability parameters…
- Trial name
- NCT01522456
- Testing
- Epiduo Gel, Retin-A Micro Microsphere 0.1%
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Galderma R&D
Acne
Cutaneous Acceptability, Comedogenic Potential and Efficacy of Two Cosmetic Products Used in Synergy
The open, intra-individual study aims to assess the cutaneous acceptability, comedogenic potential and efficacy of a cleansing gel and a cream used in synergy to relieve patients presenting with acne grade 2 and 3.
- Trial name
- NCT05490537
- Where
- 2 sites in Mauritius, Poland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Acne, Acne Vulgaris
A Clinical Trial Examining the Efficacy of a Novel Acne Treatment Serum
This single-group, open-label clinical trial examines the efficacy of Cool as a Cucumber's Acne Treatment Serum in adults with acne-prone skin.
- Conditions
- Acne, Acne Vulgaris, Skin Health
- Trial name
- NCT07752368
- Testing
- Acne Treatment Serum
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Parea INC dba Cool as a Cucumber
Acne Vulgaris
AkLief Evaluation in Acne-induced Post-Inflammatory Hyperpigmentation
The purpose of this study is to evaluate the efficacy and safety of Trifarotene 50 microgram per gram (mcg/g) cream compared to its vehicle cream in the treatment of moderate acne vulgaris with risk of acne-induced post…
- Trial name
- LEAP (NCT05089708)
- Testing
- Trifarotene Cream, Trifarotene Vehicle Cream
- Where
- 25 sites in United States, Spain
- Volunteers
- 123 people
- Sponsor
- Galderma R&D
Acne
A Clinical Trial to Evaluate the Effectiveness of an Acne Serum in Improving Facial Acne and Post-Acne Pigmentation
This study will evaluate the efficacy of the Rael Miracle Clear Complete Acne Serum product in improving facial acne and post-acne pigmentation. This study will last for 56 days.
- Trial name
- NCT06120452
- Testing
- Rael Miracle Clear Complete Acne Serum
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rael
Acne Vulgaris
Open-label Safety and Tolerability Study of LTS-PDT in Healthy Volunteers
The purpose of this study is assess the safety and tolerability of lemuteporfin topical solution (LTS) with exposure to red light (PDT), when applied to the backs of healthy volunteers.
- Trial name
- NCT01830764
- Testing
- Red Light (PDT)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Dermira, Inc.
Moderate to Severe Acne Vulgaris
Study to Evaluate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Effects of Repeat Topical Application of BOS-356 in Subjects With Moderate to Severe Acne Vulgaris
This study is being conducted to characterize the safety and tolerability of BOS-356 in adult participants with moderate to severe acne vulgaris following 14 days or 28 days of repeated topical application
- Trial name
- NCT04163263
- Testing
- BOS-356, Vehicle
- Where
- 7 sites in United States, Canada
- Volunteers
- 66 people
- Sponsor
- Boston Pharmaceuticals
Bone and Joint Prosthetic Infections
BJI Inoplex 2 : Test for Diagnosis of Prosthetic Infections
A national, prospective, open-label, non-interventional, multicentre, controlled study designed to evaluate a diagnostic method in patients undergoing hip, knee or shoulder prosthetic removal regardless of whether or not…
- Trial name
- NCT02222792
- Where
- 2 sites in France
- Volunteers
- 540 people
- Sponsor
- Diaxonhit
Acne
Absorption and Systematic Pharmacokinetics of IDP-121 Lotion in Subjects With Acne Vulgaris
Open-Label study designed to assess the safety and plasma PK of tretinoin and relevant metabolites after topical dermal application of IDP-121 lotion.
- Trial name
- NCT02849860
- Testing
- IDP-121 Lotion
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Bausch Health Americas, Inc.