Clinical trials: acne
Atrophic Acne Scar
Combined LASERs and PRP for Postacne Scars
This study evaluates a new combined technique using two different laser wavelengths and Platelets Rich Plasma (PRP) to treat post-atrophic acne scars.
- Trial name
- NCT03809416
- Testing
- Lasers, Platelets Rich Plasma, Lasers plus Normal Saline Solution
- Where
- 2 sites in Italy, Kuwait
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- DEKA S.r.l.
Acne Vulgaris
Evaluation of Topical Dutasteride as a Potential New Therapy for Facial Acne Vulgaris Versus the Triple Combination Therapy (Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel)
Acne vulgaris (AV) is one of the most prevalent dermatological conditions worldwide, affecting approximately 85% of adolescents and young adults between the ages of 12 and 24 years .While acne is often self-limiting, it can have…
- Trial name
- NCT07421804
- Testing
- topical dutasteride
- Volunteers
- 50 people
- Sponsor
- Assiut University
Acne Vulgaris
A 2 Period Cross-over Pharmacokinetic Study of SB204 in Acne Vulgaris
This study will identify how much (if any) drug is absorbed from the skin of subjects with acne vulgaris after topical application of SB204.
- Trial name
- NCT02164084
- Testing
- SB204, Vehicle Gel
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Novan, Inc.
Acne Vulgaris, Thyroid Dysfunction
Thyroid Dysfunction in Female Patients With Acne Vulgaris: [ Relation to Other Variables ]
Acne is a chronic inflammatory disease of the pilo-sebaceous unit with a multi-factorial etiology. It is one of the most frequent cutaneous diseases, affecting more than eighty percent of the population at some point in their…
- Trial name
- NCT03602534
- Where
- Egypt
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Assiut University
Acne Scarring
Microneedling Plus the Universal Peel For Acne Scarring
Acne is a prevalent disorder mostly witnessed in adolescents, but can be seen in adults. Early treatment is imperative to reduce acne scarring which can appear with atrophic lesions, and depending on the skin type, significant…
- Trial name
- NCT02174393
- Testing
- Universal Peel, Microneedling, Post-Microneedling Skin Care
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Englewood Hospital and Medical Center
Acne
St. John's Wort Photodynamic Therapy
The investigators aimed to evaluated the efficacy and safety of SJW-PDT compared to indole-3-acetic acid (IAA)-PDT in the treatment of acne. The investigators also investigated the skin rejuvenating effects of SJW-PDT.
- Trial name
- SJWPDT (NCT05073211)
- Testing
- PDT
- Where
- South Korea
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Acne
Efficacy of Cosmetic Product RV3278B-OS0386 in the Maintenance Phase After Oral Isotretinoin Treatment of Adults Subjects With Facial Acne.
The aim of this study is to evaluate the efficacy of the RV3278B-OS0386 cosmetic product, compared to the control product in managing acne relapse during the 12-month maintenance phase follow-up after oral isotretinoin treatment…
- Trial name
- NCT07341659
- Testing
- Test product RV3278BB-OS0386, Control product RV3278B-OS0548
- Where
- 5 sites in France, Italy and 1 more
- Volunteers
- 102 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
Anterior Cutaneous Nerve Entrapment Syndrome, Nerve Entrapment Syndrome
Sodium Channel Mutations in Patient With the Anterior Cutaneous Nerve Entrapment Syndrome (ACNES)
The goal of this observational study is to learn about sodium channel (Nav) mutations in patients with the Anterior Cutaneous Nerve Entrapment Syndrome (ACNES).
- Conditions
- Anterior Cutaneous Nerve Entrapment Syndrome, Nerve Entrapment Syndrome, Chronic Pain Syndrome
- Trial name
- Nav-ACNES (NCT05877274)
- Testing
- Sodium channel mutation
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Maxima Medical Center
Acne, Adult
Normaderm Phytosolution Global Observational Study
The objective of this 3-month observational study was to assess, in 2827 adults, the benefit of NP alone or as adjunctive or maintenance care in mild acne, or as adjunctive care in subjects with moderate acne.
- Trial name
- NCT05483205
- Testing
- Normaderm Phytosolution Double-Correction Daily Care Moisturizer
- Where
- 11 sites in Argentina, Bulgaria and 9 more
- Volunteers
- 2,827 people
- Sponsor
- Cosmetique Active International
Acne
Efficacy and Safety of STBF Photodynamic Therapy for Moderate and Severe Acne Vulgaris
This study is being done to evaluate the efficacy and safety of Shengtaibufen photodynamic therapy (STBF-PDT) for treatment of moderate or severe acne vulgaris.
- Trial name
- NCT05245045
- Testing
- Shengtaibufen Photodynamic Therapy(STBF-PDT), Red light
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Dermatology Hospital
Acne
Absorption and Systematic Pharmacokinetics of Topically Applied IDP-120 Gel
Study designed to assess the safety and plasma PK of tretinoin and its metabolites from topically applied IDP-120 gel.
- Trial name
- NCT02850003
- Testing
- IDP-120 Gel
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Bausch Health Americas, Inc.
Acne Vulgaris
Comparison of Epiduo Associated With Lymecycline Versus Epiduo Vehicle Associated With Lymecycline in Acne Vulgaris
Randomized, controlled, multi-center, double-blind, parallel-group comparison study in Subjects with moderate to severe acne vulgaris on the face.
- Trial name
- TEAM (NCT01014689)
- Testing
- Adapalene/ BPO gel with Lymecycline capsules, Adapalene/ BPO vehicle gel with Lymecycline capsules
- Where
- 28 sites in Australia, Belgium and 7 more
- Volunteers
- 378 people
- Sponsor
- Galderma R&D
Atrophic Acne Scars, Acne Vulgaris
Microneedling With Glycolic Acid or Trichloroacetic Acid for Atrophic Acne Scars
Atrophic acne scars are depressed scars that can remain after acne has healed. Microneedling is a procedure that uses very small needles to create controlled micro-injuries in the skin, which may stimulate collagen production and…
- Trial name
- NCT07797517
- Testing
- Microneedling only, Microneedling with Glycolic Acid 35% Peel, Microneedling with Trichloroacetic Acid 15% Peel
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Acne Vulgaris
A Dose-ranging Study of DRM01 in Subjects With Acne Vulgaris
The objectives of this study are to assess the safety and efficacy DRM01 Topical Gel compared to vehicle in patients with acne vulgaris.
- Trial name
- NCT02431052
- Testing
- Olumacostat Glasaretil, Vehicle
- Where
- 34 sites in United States, Canada
- Volunteers
- 420 people
- Sponsor
- Dermira, Inc.
Acne Vulgaris
A Study on Safety and Preliminary Efficacy of ALA in Acne Vulgaris
The purpose of this study is to explore the safety, tolerability, and preliminary efficacy of ALA used with photodynamic therapy for the treatment of moderate to severe acne vulgaris.
- Trial name
- NCT04018885
- Testing
- ALA 2.5%, ALA 5%, ALA 10%
- Where
- 4 sites in China
- Volunteers
- 72 people
- Sponsor
- Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.
Acne
Adapalene-Benzoy Peroxide (BPO) Gel in the Treatment of Acne Vulgaris as a 6-month Maintenance
The purpose of this study is to demonstrate the efficacy of Adapalene 0.1% /Benzoyl Peroxide 2.5% Gel compared to its Vehicle Gel as an acne maintenance treatment in Subjects previously treated with Adapalene-BPO Gel or…
- Trial name
- ACCESS II (NCT00687908)
- Testing
- Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel, Vehicle Gel
- Where
- 33 sites in United States, Canada and 1 more
- Volunteers
- 243 people
- Sponsor
- Galderma R&D
Acne Vulgaris
A Study to Evaluate the Efficacy and Safety of Imsidolimab (ANB019) in the Treatment of Participants With Acne Vulgaris
Efficacy and Safety of Imsidolimab in Participants with Acne Vulgaris
- Trial name
- NCT04856917
- Testing
- Imsidolimab
- Where
- 15 sites in United States, Canada
- Volunteers
- 123 people
- Sponsor
- Vanda Pharmaceuticals
Acne Vulgaris
Japanese Phase 1 Study of GSK2585823
This is a randomized, single-center, partial-blind study to evaluate the dermal irritation potential and to detect photo-toxicity and photo-allergy potential of GSK2585823, Benzoyl peroxide BPO 5% gel, Benzoyl peroxide 3% gel…
- Trial name
- JPN P1 (NCT01428466)
- Testing
- GSK2585823, Benzoyl peroxide 3%, Benzoyl peroxide 5%
- Where
- Japan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Hair Loss, Skin Laxity
Nourishing Hair, Skin & Nails Supplement Study (Derm Aid)
A 90 day eight arm virtual interventional study looking at the impact of various supplement formulations for improves in hair, skin \& nail health via self report, and dermatology assessment via remote dermatologist assessment.
- Conditions
- Hair Loss, Skin Laxity, Cosmetic Acne, Nails; Soft
- Trial name
- NCT04249128
- Testing
- Vegetarian Collagen, Keratin, Ceramides
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- ProofPilot
Acne Vulgaris
Correlation Between Acne Vulgaris and Lipid Profile Among Young Adults in Sohag Governorate
Acne vulgaris is the most common skin condition affecting late adolescents worldwide.1 The prevalence of acne is said to be 85% in adults aged 12 to 25 years.2 Almost all teenagers between 15 and 17 years report having some…
- Trial name
- NCT07062081
- Testing
- lipid profile
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
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