Clinical trials: acne
Acne Vulgaris
Self-Administered Intralesional Injections for Acne
The goal of this clinical trial is to test the safety of intralesional injections of triamcinolone self-administered into acne lesions via an injection assistance device.
- Trial name
- NCT06186596
- Testing
- Triamcinolone delivered via injection assistance device
- Where
- 3 sites in United States
- Volunteers
- 150 people
- Sponsor
- ACOM Labs
Low Level Laser Therapy, Acne Vulgaris
Low Level Laser Versus Polarized Light in the Treatment of Acne Vulgaris
The present study is designed to compare clinically the therapeutic applications between low level laser therapy (excimer laser) and non-laser polarized light (Bioptron prol) in the treatment of Acne vulgaris.
- Trial name
- NCT06867276
- Testing
- Excimer laser, Bioptron Pro 1
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Acne Vulgaris
DMT310-009 Topical in the Treatment of Acne Vulgaris
The objective is to evaluate the tolerability, safety, and efficacy of DMT310 topical powder mixed with diluent in male and female patients with moderate to severe facial acne vulgaris
- Trial name
- NCT06090721
- Testing
- DMT310
- Where
- 2 sites in United States
- Volunteers
- 520 people
- Sponsor
- Dermata Therapeutics
Acne Vulgaris
Study of Trifarotene Cream to Assess Risk of a Trophic Acne Scar Formation
The purpose of this study is to evaluate the safety and efficacy of trifarotene 50 microgram per gram (mcg/g) cream compared to its vehicle on the risk of formation of atrophic acne scars after 24 weeks of treatment in facial…
- Trial name
- START (NCT04856904)
- Testing
- Trifarotene Cream, Trifarotene Vehicle Cream
- Where
- 18 sites in United States, Canada and 1 more
- Volunteers
- 121 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Study of Oral Zileuton in the Treatment of Moderate to Severe Facial Acne Vulgaris
Tissue inflammation is a major component of the acne disease process. Leukotriene B4 (LTB4) is thought to be a major player in the development of tissue inflammation. Synthesis of LTB4 is controlled by the enzyme 5-lipoxygenase.
- Trial name
- NCT00098358
- Testing
- Zileuton
- Where
- 12 sites in United States
- Volunteers
- 90 people
- Sponsor
- Critical Therapeutics
Hidradenitis Suppurativa
Hidradenitis - an Analysis of Genetic Traits and Linkages in Families
The aim of this study is to find a genetic link or family trait connecting persons with Hidradenitis Suppurativa (HS) to each other. As a result, discover the cause and perhaps treatment for Hidradenitis Suppurativa (HS).
- Trial name
- NCT05710393
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- University of Chicago
Hidradenitis Suppurativa (HS)
A Study to Evaluate the Long-Term Safety and Efficacy of Povorcitinib in Participants With Moderate to Severe Hidradenitis Suppurativa
The purpose of this study is to evaluate long-term safety and efficacy of povorcitinib in participants with moderate to severe hidradenitis suppurativa who completed the 54 weeks of study treatment within the originating parent…
- Trial name
- STOP-HS LTE (NCT06212999)
- Testing
- Povorcitinib
- Where
- 165 sites in United States, Australia and 15 more
- Volunteers
- 617 people
- Sponsor
- Incyte Corporation
Acne, Acne Vulgaris
A Pilot Study to Evaluate the Effect of a Probiotic Mixture in Acne
A 12-week randomized, double-blind, placebo-controlled pilot study to evaluate the effect of a probiotic blend in the treatment and clinical and subjective evolution of acne vulgaris in adolescent and adult patients between 12…
- Trial name
- NCT03878238
- Testing
- Probiotic Bths-003
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Bionou Research, S.L.
Acne
Experience With Topical Acne Treatment
Acne is a chronic condition that typically requires the use of multiple medications.1 Medication adherence is especially challenging for patients with chronic diseases and often decreases over time, especially for those using…
- Trial name
- NCT05582434
- Testing
- clindamycin phosphate 1.2%/adapalene 0.15%/BPO 3.1% gel, adapalene 0.3%/BPO 2.5% gel and compounded clindamycin phosphate 1.2% gel, Compounded BPO 2.5% gel, adapalene 0.1% gel, and compounded clindamycin phosphate 1.2% gel
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Wake Forest University Health Sciences
Acne Vulgaris
Clinical Study Between Two Clindamycin 1%/Benzoyl Peroxide 5% Topical Gels
The purpose of this study is to compare the efficacy and safety profiles of Perrigo Israel Pharmaceuticals, Ltd. Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel and Benzaclin® Topical Gel (Clindamycin- Benzoyl Peroxide Gel).
- Trial name
- NCT01138514
- Testing
- Clindamycin 1% / Benzoyl Peroxide 5% (Perrigo), Clindamycin 1% / Benzoyl Peroxide 5% (Benzaclin)
- Volunteers
- 1,555 people
- Sponsor
- Padagis LLC
Acne
Study Evaluating the Efficacy and Safety of Omnilux Clear on Mitigating Mild to Moderate Acne
The goal of this clinical trial is to further substantiate the effectiveness and safety of Omnilux Clear as a stand-alone treatment of mild to moderate acne in healthy teenagers and adults 14 years of age or older over the course…
- Trial name
- NCT06936332
- Testing
- Omnilux Clear Light Emitting Diode Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ablon Skin Institute Research Center
Acne Vulgaris
Microdermabrasion for Acne
The purpose of this research project is to study the effect of micordermabrasion to try to improve the appearance of facial acne.
- Trial name
- NCT00355485
- Testing
- microdermabrasion
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Michigan
Acne Papulopustulosa
Control of Therapy of Acne Papulopustulosa by Visible Light With Waterfiltered Infrared and / or Adapalen (Differin Gel)
The aim of the study is to investigate the effectivity of visible light in combination with waterfiltered infrared in treating acne papulopustulosa.
- Trial name
- NCT00237978
- Testing
- Adapalen, VIS and wIRA
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Technische Universität Dresden
Acne Vulgaris
Low-Dose Versus Conventional-Dose Oral Isotretinoin for Acne Vulgaris
Background and Purpose: Acne vulgaris is a common skin condition that can cause significant physical and emotional distress. Oral isotretinoin is a highly effective treatment for severe or persistent acne.
- Trial name
- NCT07639073
- Testing
- Isotretinoin
- Where
- Pakistan
- Volunteers
- 164 people
- Sponsor
- Pakistan Institute of Medical Sciences
Atrophic Scar
Clinical Benefits and Safety of Combined Polynucleotides and Hyaluronic Acid - Newest - for Acne Scars Treatment
This clinical study wants to evaluate the efficacy and safety of a medical device combining "Polynucleotide Highly Purified Technology" (PN-HPT™) and hyaluronic acid (Newest-Mastelli S.r.l) for treating moderate-to-severe…
- Trial name
- NCT05936437
- Testing
- Subjects treated with Newest medical device
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Mastelli S.r.l
Acne Scars
Clinical Evaluation of Fractional Radiofrequency for the Treatment of Acne Scarring
Prospective, single centre, evaluator-blind study of the safety and performance of fractional radiofrequency (RF) for the treatment and reduction of acne scarring.
- Trial name
- NCT03767153
- Testing
- Venus Viva
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Melasma, Post-acne Hyperpigmentation
Efficacy and Safety of a Combined Serum Containing Melasyl™, 10% Niacinamide, Hyaluronic Acid, and HEPES
The goal of this clinical trial is to evaluate the efficacy and safety of a combination serum containing Melasyl™, 10% Niacinamide, Hyaluronic Acid, and HEPES when used as a moisturizer after QS-Nd:YAG 1064 nm low-fluence laser…
- Trial name
- NCT07121439
- Testing
- a combination serum containing Melasyl™, 10% Niacinamide, Hyaluronic Acid, and HEPES, 2% hydroquinone cream
- Where
- Indonesia
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Melasma, Acne Scars - Mixed Atrophic and Hypertrophic
Comparative Effects Of Trichloroacetic Chemical Peel And Fractional Laser
More than aesthetics, the search for orofacial harmonization treatments has increased when the negative emotional impact of some facial conditions such as melasma and acne scars is recognized.
- Conditions
- Melasma, Acne Scars - Mixed Atrophic and Hypertrophic, Resurfacing, Rejuvenation
- Trial name
- NCT07036302
- Testing
- 35% TCA combined with croton oil peel, Isolate 35% TCA peel, Erbium-YAG laser
- Where
- 2 sites in Brazil
- Volunteers
- 120 people
- Sponsor
- Jose Roberto Cortelli
Acne Vulgaris
Double-blinded, Vehicle Controlled Study to Evaluate Efficacy & Tolerance of Bakuchiol and Ethyl Linoleate on Acne
Subjects will be assigned to a active cream or vehicle to compare the cosmetic effects. This will take place over a 12 week period.
- Trial name
- NCT05069272
- Testing
- Bakuchiol and Ethyl Linoleate, Vehicle
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ratan K. Chaudhuri
Acne
Topical Palm Tocotrienols on Blemish-prone Skin
A single-center, double-blind, randomised, placebo-controlled parallel-group study. Selected subjects will be randomised into active and control groups in a ratio of 1:1.
- Trial name
- NCT05756881
- Testing
- Cosmetic product
- Where
- Malaysia
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
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