Clinical trials: acne
Acne Vulgaris, Acne Vulgaris Superficial Mixed Comedonal and Inflammatory
Full Spectrum Hemp Observational Study
In westernized societies, acne vulgaris is nearly a universal skin disease afflicting 79% to 95% of the adolescent population; older than 25 years - 40% to 54% have facial blemishes and persists into middle age in 12% of women…
- Trial name
- NCT04730414
- Testing
- Full-spectrum hemp (0.018% THC)
- Volunteers
- 50 people
- Sponsor
- Charlotte's Web, Inc
Hidradenitis Suppurativa, Mediterranean Diet
Nutritional Status and Hidradenitis Suppurativa (Acne Inversa)
Hidradenitis suppurativa (HS) is a chronic inflammatory, debilitating skin disorder. The exacerbating factors of HS include nutrition and adiposity.
- Conditions
- Hidradenitis Suppurativa, Mediterranean Diet, Body Composition, Vitamin D Deficiency
- Trial name
- NutriHidra (NCT03683238)
- Testing
- Mediterranean Diet
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Federico II University
Acne
Anti-acne Efficacy of a Dermo-cosmetic Product Associated With the Fixed Combination Adapalene 0.1%/ Benzoyl Peroxide 2.5% Treatment Versus This Treatment Associated With a Standard Moisturizer in Male and Female Subjects Presenting With Mild to Moderate Acne
Study to evaluate the anti-acne efficacy of a dermo-cosmetic associated with the fixed combination Adapalene 0.1%/ benzoyl peroxide 2.5% treatment and to demonstrate that the dermo-cosmetic product can improve the local tolerance…
- Trial name
- NCT03832647
- Testing
- Epiduo, Salicylic Acid, Hydréane légère
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Vichy Laboratoires
Acne Scars - Mixed Atrophic and Hypertrophic
Early Non-Ablative Fractional Laser Resurfacing for Acne Scars After Treatment With Oral Isotretinoin
Patients who have completed have completed a cumulative dose of >=120miligram/kilogram oral isotretinoin within the last 30 days, and has mild to moderate acne scarring will be randomized, into a right-left comparison study using…
- Trial name
- NCT03514771
- Testing
- Fraxel DUAL 1550/1927, oral isotretinoin, oral valacyclovir
- Volunteers
- 15 people
- Sponsor
- David Smart
Acne Vulgaris, Gingivitis
Association of Acne Vulgaris With Oral Hygiene and Gingivitis
The goal of this observational study is to learn about in the relationship between acne vulgaris and oral hygiene and gingivitis.
- Conditions
- Acne Vulgaris, Gingivitis, Dental Plaque, Oral Hygiene
- Trial name
- NCT06237387
- Testing
- Periodontal examination
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Erzincan University
Acne Vulgaris Superficial Mixed Comedonal and Inflammatory
Evaluation of Efficacy of Topical Flutamide in the Treatment of Acne Vulgaris
From the obtained results, topical Flutamide 1% gel can be a promising, effective, and safe alternative in treating patients with acne vulgaris with minimal side effects.
- Trial name
- NCT05478330
- Testing
- Flutamide 1% gel, topical gel without flutamide
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Acne Vulgaris
The Functional and Emotional Benefits of Replenix Power of Three With Resveratrol
A Randomized, Investigator Blinded, Single Site, Three Arm Clinical Study to Assess the Functional and Emotional Benefits of Replenix Power of Three Cream with Resveratrol , Replenix Power of Three Cream with Resveratrol with…
- Trial name
- NCT03563365
- Testing
- Replenix Power of 3 Cream with resveratrol, Adapalene and Benzoyl peroxide gel, 0.1%/2.5%
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Yardley Dermatology Associates
Acne Scars
Effect of Multiple Subcisions on Rolling Acne Scars
The purpose of this study is to find out whether the use of multiple subcisions over several visits will improve the appearance of rolling acne scars compared to no treatment.
- Trial name
- NCT02216864
- Testing
- Multiple Subcision
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Acne Vulgaris
A Phase 1, 3 Day Study of Safety and Tolerability of NVN1000 Topical Gel in Healthy Volunteers
A Phase I, Single-Center, Open-Label, Randomized, Parallel Group, 3 Day Study Evaluating the Safety and Cutaneous Tolerability of NVN1000 Topical Gel in Healthy Volunteers
- Trial name
- NCT01755247
- Testing
- Topical Gel Vehicle, 8% NVN1000 Topical Gel, 8% NVN1000 Topical Gel and moisturizer
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Novan, Inc.
Facial Acne, Local Adverse Effects
Dermatologists' Educational Demonstration for Epiduo Application
The purpose of this study is to evaluate the efficacy and tolerability of this combination gel compared with BPO monotherapy in Korean patients, and test clinical practicability of dermatologists' educational demonstration for…
- Trial name
- NCT02192632
- Testing
- Epiduo once daily with detailed instruction for how to apply it, Epiduo- once daily, simple instruction for application, BPO once daily
- Where
- South Korea
- Volunteers
- 85 people
- Sponsor
- Seoul National University Hospital
Acne Rosacea
DMT210 Topical Gel in the Treatment of Acne Rosacea
The study evaluates the safety, tolerability, and efficacy of DMT210 Gel, 5% when applied twice daily for 12 weeks in adult patients with moderate to severe acne rosacea.
- Trial name
- NCT03003104
- Testing
- DMT210 Topical Gel 5%, Vehicle Control
- Where
- 9 sites in United States
- Volunteers
- 107 people
- Sponsor
- Dermata Therapeutics
Acne Vulgaris
A Clinical In-Use Evaluation to Assess the Tolerability and Efficacy of a Moisturizer on Acne Prone Skin
The objective of this study is to evaluate the tolerance and efficacy of a facial moisturizer in subjects with mild to moderate acne vulgaris over a 4-week treatment period.
- Trial name
- NCT07224633
- Testing
- Use of Barrier Building Moisturizer
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Kenvue Brands LLC
Facial Acne Vulgaris
Retinyl Palmitate-loaded Ethosomes in Acne Vulgaris
Acne is a chronic inflammatory dermatosis of the pilosebaceous unit. Topical treatment is the first choice in mild and moderate cases of acne, especially topical retinoids.
- Trial name
- NCT04080869
- Testing
- retinyl palmitate, Tretinoin
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Assiut University
Acne Vulgaris
Patient-reported Outcomes for Sarecycline Effectiveness and Safety (PROSES)
The purpose of this study is to evaluate the patient-reported outcomes (PROs) in terms of health-related quality of life (HRQoL) and signs of Acne Vulgaris (AV) among patients with moderate to severe non-nodular AV who are…
- Trial name
- PROSES (NCT04820673)
- Testing
- Sarecycline
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Almirall, S.A.
Acne Vulgaris
Clinical Pharmacist Role in Adherence to Recommendations Among Isotretinoin Users
The objective of the study was to evaluate the role of clinical pharmacists in improving adherence to medication and the recommendations related to isotretinoin, awareness about proper use, dealing with the side effects, and…
- Trial name
- NCT05839223
- Testing
- Education
- Where
- Jordan
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Acne Vulgaris
A Phase 1 Study Assessing Local Cutaneous Effects of SB204
In this study, color (erythema) and pH will be measured on 3 consecutive days after application of 2 doses of SB204 to the cheeks of healthy volunteers.
- Trial name
- NCT02250430
- Testing
- SB204
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Novan, Inc.
Acne, Acne Scars
The Suitability of Tience® for Treating Acne Scars
This is an open-label, single-center, split-face, pseudo-randomized clinical trial designed to evaluate the efficacy and safety of a human-derived, cell-free adipose tissue derivative (Tience® ), for treating moderate to severe…
- Trial name
- NCT07368764
- Testing
- Intradermal injections
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Linio Biotech Oy
Acne
Bioequivalence Study of Tretinoin Gel 0.05% to Brand Tretinoin Gel
This was a double-blind, randomized, three-treatment, parallel study. Normal, healthy male and female children and adults (i.e., ages 12 to 40 years) with at least Grade 2 (i.e., mild severity) acne vulgaris were treated on the…
- Trial name
- NCT02249767
- Testing
- Tretinoin
- Volunteers
- 574 people, healthy volunteers welcome
- Sponsor
- Spear Pharmaceuticals
Cutibacterium Acnes Contamination
Wound Irrigation Comparative Effectiveness Study
The primary objective of this study is to compare the presence of C acnes in bacteriologic cultures taken from participant samples of subcutaneous and deep tissue prior to deep surgical irrigation using either Normal Saline…
- Trial name
- NCT06379919
- Testing
- Irrisept Irrigation, Saline Irrigation Solution Delivery
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Education and Research Institute (dba Hoag Orthopedics)
Acne Vulgaris
A Trial of Pulse Dyed Laser (Chromogenex Regenlite Transform) in the Treatment of Inflammatory Acne Vulgaris
A Randomized, Blinded, Single-Centered, Placebo-Controlled Trial of Pulse Dyed Laser (Chromogenex Regenlite Transform) in the Treatment of Inflammatory Acne Vulgaris
- Trial name
- Chromogenix (NCT02647528)
- Testing
- Chromogenix Regenlite Transform Treatment
- Where
- United States
- Sponsor
- Sadick Research Group
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