Clinical trials: acne
Muscle Strength
Effect of Oral Isotretinoin on Muscle Strength in Patients With Acne Vulgaris: A Prospective Controlled Study
BACKGROUND: Musculoskeletal side effects related to isotretinoin are frequently reported. This study aimed to investigate the effect of oral isotretinoin treatment on muscle strength.
- Trial name
- NCT04626817
- Testing
- Isokinetic device (Biodex System 4)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cevriye Mülkoğlu
Acne Vulgaris
Clinical Study to Evaluate Tolerability and Safety of ARK-E021 Foam and to Monitor Clinical Effect in Acne Vulgaris Patients
This is a multicenter, randomized, double-blind, placebo-controlled, 3-arm, parallel-group, ambulatory safety and efficacy study of ARK-E021 topical foam of 5% and 10% in subjects with mild to moderate acne vulgaris.
- Trial name
- NCT01494285
- Testing
- ARK-E021 5%, ARK-E021 10%
- Where
- 3 sites in Israel
- Volunteers
- 157 people
- Sponsor
- M. Arkin 1999 Ltd.
Acne
Efficacy Study of Cosmetic Product RV3278AET0943 Versus Non-treated Group in Adults With Oily and Acne Prone Skin
The aim of this study is to evaluate, at different times, the RV3278A - ET0943 cosmetic product efficacy after 8 weeks of application on the face (twice-daily application).
- Trial name
- NCT04873089
- Testing
- Cosmetic product
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Acne Scars
Comparison of Picosecond Pulsed Nd:YAG Laser and Fractional Laser for the Treatment of Acne Scars
This study compares the application of a picosecond 1064-nm laser with a diffractive lens array with nonablative fractional laser for the treatment of acne scarring.
- Trial name
- NCT03850925
- Testing
- Laser therapy
- Where
- South Korea
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Dongtan Sacred Heart Hospital
Atrophic Acne Scar
SkinPen Efficacy on Acne Scars on the Face and/or Back
This single-center, clinical trial will take place over a 90 day course followed by 1-month and 6-month post treatment visits to assess the efficacy and tolerability of the SkinPen device when used on both men and women on the…
- Trial name
- NCT02646917
- Testing
- Aesthetic Microneedling Treatment
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Bellus Medical, LLC
Acne Vulgaris
To Evaluate the Therapeutic Equivalence and Safety of TRETINOIN CREAM, 0.05% and RLD in the Treatment of Acne Vulgaris
Bioequivalence study comparing Tretinoin Cream, 0.05% to RETIN-A®.
- Trial name
- NCT03433378
- Testing
- Tretinoin cream, 0.05%, RETIN-A® (tretinoin) cream, 0.05%, Vehicle of the test product
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Acne Rosacea
A Pilot Study on the Use of Seysara for Rosacea
This is a prospective, parallel group, randomized, investigator-blinded pilot study. Approximately 100 subjects will be randomized at a 3:1 ratio to Seysara (sarecycline) at a weight-based dose per label or Centrum Adult…
- Trial name
- NCT04555525
- Testing
- sarecycline, Centrum Adult Multivitamin
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Derm Research, PLLC
Acne Vulgaris
Effect of Systemic Isotretinoin on Serum Irisin Level in Acne Vulgaris Patients
Acne vulgaris is a chronic inflammatory skin disease affecting the pilosebaceous unit. It is clinically characterized by comedones, papules, pustules, nodules, cysts and scarring on the face and trunk.
- Trial name
- NCT05869188
- Testing
- Isotretinoin
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- South Valley University
Cutibacterium Acnes
Do Wound Protectors Reduce Contamination in Total Shoulder Arthroplasty?
Prosthetic joint infection is a devastating complication of shoulder arthroplasty. A relatively novel method of preventing PJI has been with the use of a wound protection device.
- Trial name
- NCT06513182
- Testing
- No Alexis orthopaedic protector, Alexis orthopaedic protector
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah
Acne
Phase 1 Study to Evaluate the Safety, Tolerability, PK, and PD of TVB-3567 in Healthy Participants With or Without Acne
This is a 4-part study. Part A will be a randomized, double-blind, placebo-controlled investigation of single ascending doses (SAD) to assess the safety, tolerability, pharmacokinetics (PK), and pharmacodynamic (PD) biomarkers of…
- Trial name
- NCT06989840
- Testing
- TVB-3567
- Where
- 6 sites in United States, Australia
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Sagimet Biosciences Inc.
Acne Vulgaris
Multi-center, Randomized, Double-blind Efficacy and Safety of CD0271 0.3%/CD1579 2.5 % Topical Gel in Acne Vulgaris
The study hypothesis are based on the assumption that : CD0271 0.3%/CD1579 2.5% Gel provides superior clinical efficacy compared with Topical Gel Vehicle in the overall population and in the subgroup of severe Subjects CD0271…
- Trial name
- NCT01880320
- Testing
- CD0271 0.3% / CD1579 2.5%, CD0271 0.1% / CD1579 2.5%, Topical Gel Vehicle
- Where
- 31 sites in United States, Canada
- Volunteers
- 503 people
- Sponsor
- Galderma R&D
Acne Vulgaris
An Evaluation of the Adrenal Suppression Potential and PK of CB-03-01 Cream in Pediatric Patients With Acne Vulgaris
This study is designed to determine the hypothalamic-pituitary-adrenal (HPA) axis suppression potential and pharmacokinetic (PK) properties of CB-03-01 Cream, 1%, applied every twelve hours for two weeks, in pediatric patients 9…
- Trial name
- NCT02720627
- Testing
- cortexolone 17α-propionate
- Where
- 10 sites in United States, Poland
- Volunteers
- 27 people
- Sponsor
- Cassiopea SpA
Acne Atrophica
The Efficacy and Safety of Dezocine Pretreatment for Pain Relief in Acne Scar Treatment of Fractional CO2 Laser
The Efficacy and Safety of Dezocine Pretreatment for Pain Relief in Acne Scar Treatment of Fractional CO2 Laser
- Trial name
- NCT05861063
- Testing
- Fractional CO2 laser, Dezocine
- Where
- China
- Volunteers
- 105 people
- Sponsor
- Xijing Hospital
Acne Vulgaris
A Study to Compare Efficacy and Safety of Trifarotene Cream When Used With an Oral Antibiotic for the Treatment of Severe Acne Vulgaris (AV)
The purpose of this study was to demonstrate that daily use of topical trifarotene (CD5789) 50 microgram per gram (mcg/g) cream when used in association with oral antibiotic is safe and effective for the treatment of severe AV.
- Trial name
- DUAL (NCT04451330)
- Testing
- Trifarotene cream, Doxycycline hyclate, Trifarotene Vehicle
- Where
- 26 sites in United States, Puerto Rico
- Volunteers
- 202 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Safety and Efficacy Study of Acnase Creme in the Treatment of Acne Vulgaris I and II
The objective of this study is to establish the safety in use of the topical drug Acnase Creme and its effectiveness in treatment of acne grade I (comedones) and II (comedones, papules, pustules).
- Trial name
- ACNASE (NCT00877409)
- Testing
- Benzoyl Peroxide 5% and Sulphur 2%, Vehicle of Acnase
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Zurita Laboratorio Farmaceutico Ltda.
Wrinkle, Photoaging
An Exploratory Investigation of a Novel Skincare Regimen
This trial will assess the effectiveness of the Aria Trio Complete Facial system in being able to reduce blemishes, lines, and wrinkles.
- Conditions
- Wrinkle, Photoaging, Acne, Skin Inflammation
- Trial name
- NCT05517720
- Testing
- Aria Trio complete Facial System
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Trophy Skin
Keloid, Scleroderma
UVA1 Light for Scleroderma and Similar Conditions
The purpose of this investigation is to evaluate the effectiveness of high-dose UVA1 irradiation in the treatment of fibrosing conditions of the skin, e.g., keloid (a thick scar from growth of fibrous tissue), scleroderma…
- Conditions
- Keloid, Scleroderma, Scars, Granuloma Annulare
- Trial name
- NCT00476697
- Testing
- German manufactured UVA1 emitting light system
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Michigan
Acne Vulgaris
Efficacy and Safety of CD5789 (Trifarotene) 50μg/g Cream Versus Vehicle Cream in Acne Vulgaris
Assessment of the efficacy and safety of CD5789 (trifarotene) 50μg/g cream applied once daily for 12 weeks in subjects with acne vulgaris.
- Trial name
- NCT02566369
- Testing
- CD5789 (trifarotene) 50μg/g cream
- Where
- 124 sites in United States, Canada and 3 more
- Volunteers
- 1,208 people
- Sponsor
- Galderma R&D
Acne Vulgaris
A Phase 3 Study to Compare the Safety and Efficacy of 5% Dapsone Topical Gel, (DTG) Twice Daily in Combination With Once Daily Vehicle Control, Adapalene Gel 0.1% or Benzoyl Peroxide Gel 4%
The purpose of this study is to compare the safety and efficacy of 5% Dapsone Topical Gel, (DTG) twice daily in combination with once daily vehicle control, adapalene gel 0.1% or benzoyl peroxide gel 4%.
- Trial name
- NCT00151541
- Testing
- Dapsone Topical Gel + adapalene gel 0.1%, Dapsone Topical Gel + benzoyl peroxide gel 4%, Dapsone Topical Gel + vehicle control
- Volunteers
- 301 people
- Sponsor
- Allergan
Acne Scarring of the Face
Safety and Efficacy Study of Autologous Fibroblasts in the Treatment of Severe Facial Acne Scarring
The purpose of this study is to evaluate the safety profile and the treatment effect of Isolagen TherapyTM and placebo when administered to facial acne scars.
- Trial name
- NCT00642642
- Testing
- Autologous Human Fibroblasts (azficel-T)
- Where
- 7 sites in United States
- Volunteers
- 122 people
- Sponsor
- Castle Creek Biosciences, LLC.
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