Clinical trials: acne
Acne Atrophica
Monopolar Radiofrequency Versus Pulsed Dye Laser for Treatment of Acne Scars
Background: The acne scar is a common disorder characterized by skin eruption or abnormalities on face, chest, and/or back in the adolescence which affect the cosmetic appearance.
- Trial name
- MRFPDL (NCT04461366)
- Testing
- Monopolar radiofrequency, Pulsed dye laser
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Hidradenitis Suppurativa
A Study to Evaluate the Efficacy and Safety of AVTX-009 in Patients With Moderate to Severe Hidradenitis Suppurativa
The main purpose of this study is to evaluate the efficacy and safety of AVTX-009 compared with placebo in patients with moderate to severe Hidradenitis Suppurativa (HS).
- Trial name
- LOTUS (NCT06603077)
- Testing
- AVTX-009 Regimen 1, AVTX-009 Regimen 2
- Where
- 89 sites in United States, Australia and 11 more
- Volunteers
- 253 people
- Sponsor
- Avalo Therapeutics, Inc.
Acne Scars
A Pilot Study Testing the Efficacy of a Needling Device for the Treatment of Acne Scars
The primary objective of this study is to determine the efficacy of a needling device for treatment of acne scars.
- Trial name
- NCT00974870
- Testing
- needling treatment
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Acne Vulgaris
Study to Evaluate the Safety, Tolerability and Pharmacokinetic of Single and 14 Day Repeat Topical Application of GSK1940029
The proposed indication for GSK1940029 is topical treatment of acne, the early clinical plan will evaluate the irritation potential of GSK1940029 (Study SCD117225 - 3 Part study); and safety, tolerability and pharmacokinetics of…
- Trial name
- NCT01938482
- Testing
- 0.3% GSK1940029 gel, 1% GSK1940029 gel, 0.3%/1% vehicle gel only
- Where
- Australia
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Acne Vulgaris
A Study to Evaluate the Pharmacokinetics of Benzoic Acid and Hippuric Acid After Topical Administration of GSK2585823 in Japanese Subjects With Acne Vulgaris
This is a Phase 1, single-center, open-label study to evaluate the pharmacokinetics of the BPO metabolites benzoic acid and hippuric acid with 7-day repeat application of GSK2585823 in subjects with acne vulgaris
- Trial name
- NCT01527123
- Testing
- GSK2585823
- Where
- Japan
- Volunteers
- 12 people
- Sponsor
- GlaxoSmithKline
Acne
A Clinical Trial to Investigate the Efficacy and Safety of GenLabs' Social Renew on Improving Acne Symptoms and Skin Repair Among Healthy Adults
The goal of this interventional clinical trial is to investigate the efficacy and safety of GenLabs' Social Renew on improving acne symptoms and skin repair among healthy adults.
- Trial name
- NCT07127523
- Testing
- Social Renew
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- GenCanna Acquisition Corp
Acne Vulgaris
A Study to Evaluate the Safety and Efficacy of Tazarotene Foam, 0.1%, in Subjects With Common Facial Acne - W0260-301
The purpose of this study is to assess safety and efficacy of a new foam formulation of tazarotene in subjects with acne vulgaris.
- Trial name
- NCT01017146
- Testing
- Tazarotene foam, Vehicle Foam
- Where
- 22 sites in United States, Canada
- Volunteers
- 744 people
- Sponsor
- Stiefel, a GSK Company
Acne Vulgaris
A Study Comparing Trifarotene Cream 0.005% to AKLIEF® Cream in the Treatment of Acne Vulgaris
To demonstrate therapeutic equivalence and safety of Trifarotene cream 0.005% (Taro Pharmaceuticals U.S.A., Inc.) and AKLIEF® cream in the treatment of acne vulgaris
- Trial name
- NCT06063473
- Testing
- Trifarotene Cream 0.005%, AKLIEF® Cream (Trifarotene 0.005%, Galderma Laboratories)
- Where
- United States
- Volunteers
- 762 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Acne Scars - Mixed Atrophic and Hypertrophic
Clinical Evaluation of the Safety and Performance of FRF for the Treatment and Reduction of Acne Scarring
Prospective, single centre, evaluator-blind study of the safety and performance of fractional radiofrequency (RF) for the treatment and reduction of acne scarring.
- Trial name
- NCT04827680
- Testing
- Venus Viva MD
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Acne Vulgaris
Excimer Light Versus Blue Light in Acne
The aim is to assess the efficacy and safety of Excimer Light versus blue light in the treatment of inflammatory acne.
- Trial name
- NCT06725303
- Testing
- Excimer
- Volunteers
- 24 people
- Sponsor
- Cairo University
Acne Vulgaris
Clinical Trial to Compare Oral Isotretinoin to Standard of Care in Moderate Acne Skin of Color Patients
In Dermatology, assessment of people of color remains underrepresented in RCTs (<10%) and guidelines. Acne affects around 9% of the population worldwide and negatively affects quality of life and self-esteem with anxiety…
- Trial name
- ETHNIC (NCT06447480)
- Testing
- ISOtretinoin 5 MG, Topical cream
- Where
- 19 sites in France, French Guiana
- Volunteers
- 420 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Hidradenitis Suppurativa
An Investigation Into the Efficacy of Provodine Topical Cream as Compared to 10% Benzoyl Peroxide Wash for the Treatment of Hidradenitis Suppurativa.
The purpose of this study is to compare the efficacy of Provodine™ topical cream to 10% benzoyl peroxide topical body wash for the treatment of early stage hidradenitis suppurativa.
- Trial name
- NCT01818167
- Testing
- 10% Benzoyl Peroxide Topical Body Wash, Provodine Topical Cream
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Hyperpigmentation, Post-inflammatory Hyperpigmentation
The Effects of Cetyl Tranexamate Mesylate on the Appearance of Acne-Related Hyperpigmentation
The purpose of this study is to assess the effects of Cetyl Tranexamate Mesylate on acne-related hyperpigmentation through a specific delivery form known as TeraCeutic TXVector.
- Conditions
- Hyperpigmentation, Post-inflammatory Hyperpigmentation, Acne
- Trial name
- NCT06080035
- Testing
- Topical Cetyl Tranexamate Mesylate
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Acne Vulgaris
Bio-equivalence Study With Clinical Endpoints in the Treatment of Acne Vulgaris
This study is to evaluate the therapeutic equivalence and safety of Taro Product to RLD in the treatment of acne vulgaris.
- Trial name
- NCT04134273
- Testing
- CLPG Topical Gel 1%, Clindamycin
- Where
- United States
- Volunteers
- 1,260 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Sebum Production, Acne Scars
SMosE Safety and Efficacy Evaluation as a Skin Adaptogen
This study evaluates the biological activity, safety, and clinical efficacy of SMosE (Shiitake Mushroom Oil-Soluble Extract), a topical cosmetic ingredient developed to support skin barrier function, adaptogenic responses, and…
- Conditions
- Sebum Production, Acne Scars, Skin Barrier to Water Loss
- Trial name
- SMosE (NCT06338046)
- Testing
- Corthellus Shiitake(Mushroom) Extract
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federico II University
Acne Vulgaris
Efficacy, Safety Profile, and Post-Acne Sequelae of 0.025% Retinoic Acid Cream vs. 0.1% Adapalene Cream in Mild Acne Vulgaris in Fitzpatrick Skin Types III-V
The goal of this clinical trial is to compare the effectiveness, safety profile, and post-acne sequelae of 0.025% retinoic acid cream versus 0.1% adapalene cream for mild acne vulgaris in individuals with Fitzpatrick skin types…
- Trial name
- NCT07015931
- Testing
- retinoic acid cream 0.025%, adapalene cream 0.1%
- Where
- Indonesia
- Volunteers
- 23 people
- Sponsor
- Universitas Indonesia
Acne
Plant-based Dietary Intervention for Treatment of Acne
The purpose of this study is to determine if a low-fat, vegan diet affects the number of acne lesions, acne severity, and acne extent.
- Trial name
- NCT00900939
- Testing
- Low-fat, vegan diet, Control
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Physicians Committee for Responsible Medicine
Acne
Non-interventional Translational Study in Mild, Moderate and Severe Acne Patients
This study aims to uncover the specific immunopathology, microbiome and pathophysiology of acne vulgaris in people living in a tropical climate such as Singapore.
- Trial name
- VBE00011 (NCT07411638)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Skin Centre
Acne Vulgaris, Acne
A Clinical Study to Evaluate the Safety and Effectiveness of an Investigational Product Called CT Gel
The purpose of this study is to demonstrate the safety and effectiveness of CT Gel in subjects with acne vulgaris. The hypothesis is that CT Gel is superior to Clindamycin Gel, Tretinoin Gel and Vehicle Gel for the treatment of…
- Trial name
- NCT00689117
- Testing
- CT Gel, Clindamycin Gel (clindamycin ), Tretinoin Gel (tretinoin)
- Where
- 32 sites in United States, Belize and 1 more
- Volunteers
- 1,649 people
- Sponsor
- Stiefel, a GSK Company
Anterior Cutaneous Nerve Entrapment Syndrome (ACNES)
Nociceptive Processing in Acute Cutaneous Nerve Entrapment Syndrome
Rationale: Chronic abdominal pain is a frequently occurring condition. Although hardly ever considered, the abdominal wall is the primary cause in 10-30% of cases.
- Trial name
- NCT01920880
- Testing
- Quantitative Sensory Testing analysis
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Radboud University Medical Center
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