Clinical trials: acne
Acne Vulgaris, Isotretinoin
Identifying the Genetic Predictors of Severe Acne Vulgaris and the Outcome of Oral Isotretinoin Treatment
The goal of this study is to enroll 250 participants that have joined the MURDOCK Study Horizon 1.5 (Duke IRB Pro00011196) with a current or prior diagnosis of severe acne AND current or prior treatment with oral isotretinoin.
- Trial name
- SA (NCT01727440)
- Where
- 6 sites in United States
- Volunteers
- 123 people
- Sponsor
- Duke University
Acne Vulgaris
A Clinical Trial Evaluating the Safety and Efficacy of IDP-110 in Patients With Acne Vulgaris
The purpose of this study is to assess the effectiveness of IDP-110 in treating patients with acne vulgaris.
- Trial name
- NCT00663286
- Testing
- IDP-110, Clindamycin, Benzoyl peroxide
- Where
- 33 sites in United States
- Volunteers
- 1,399 people
- Sponsor
- Dow Pharmaceutical Sciences
Acne Vulgaris
A Study Comparing Adapalene Gel 0.1% and to Differin Gel in the Treatment of Acne Vulgaris
To demonstrate therapeutic equivalence and safety of adapalene gel 0.1% (Taro Pharmaceuticals U.S.A., Inc.) and Differin® Gel (Adapalene Gel 0.1%, Galderma) in the treatment of acne vulgaris.
- Trial name
- NCT04797793
- Testing
- Adapalene Gel 0.1%, Differin® Gel (Adapalene 0.1%, Galderma)
- Where
- United States
- Volunteers
- 978 people, healthy volunteers welcome
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Acne Vulgaris
Clinical Study Between Two 1% Clindamycin/5% Benzoyl Peroxide Topical Gel Formulations
A randomized, double-blind, multiple-site, placebo-controlled, parallel-group clinical study conducted to evaluate the bioequivalence of two 1% Clindamycin/5% Benzoyl Peroxide Topical Gel formulations.
- Trial name
- NCT01044264
- Testing
- 1% Clindamycin/5% Benzoyl Peroxide Topical Gel
- Volunteers
- 602 people, healthy volunteers welcome
- Sponsor
- Padagis LLC
Acne Vulgaris, Acne
Study of NVN1000 Topical Gel and Topical Gel Vehicle in the Treatment of Moderate to Severe Acne Vulgaris
The primary objective of this study is to compare the tolerability, safety and efficacy of NVN1000 Topical Gel and Topical Gel Vehicle in the treatment of subjects with moderate to severe acne vulgaris.
- Trial name
- NCT01556698
- Testing
- NVN1000, Vehicle
- Where
- Dominican Republic
- Volunteers
- 70 people
- Sponsor
- Novan, Inc.
Acne Vulgaris
Intralesional Injections of Triamcinolone for Acne Vulgaris
This proof-of-concept study seeks to investigate the safety of intralesional injections of triamcinolone for acne vulgaris lesions using an Intradermal Needle Adapter.
- Trial name
- ATM-2201 (NCT06170593)
- Testing
- Triamcinolone Injection
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- ACOM Labs
Acne Vulgaris
Trial of Dapsone 5.0% Gel in the Treatment of Acne Vulgaris
Multi-center, double-blind, randomized, placebo-controlled trial of Dapsone 5.0% Gel in the treatment of acne vulgaris.
- Trial name
- NCT02865005
- Testing
- Dapsone 5.0% Gel (SEEGPharm), Dapsone 5.0% Gel (Allergan)
- Where
- 36 sites in United States, Belize
- Volunteers
- 2,361 people
- Sponsor
- Seegpharm S.A.
Acne Vulgaris
Efficacy and Tolerability of Nicotinamide Plus Cream for Moderate Acne Vulgaris in Indonesia
Acne vulgaris (AV) is a chronic inflammatory disease of the pilosebaceous unit that affects seborrheic areas such as the face, back and chest.
- Trial name
- NCT03626298
- Testing
- Adapalene, Nicotinamide, ABA and Zinc PCA
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Rumah Sakit Pusat Angkatan Darat Gatot Soebroto
Acne Vulgaris
Clinico-demographic Features of Patients With Acne Vulgaris
The Global Burden of Disease Study 2010 found that acne vulgaris is the eight most common skin disease, with an estimated global prevalence (for all ages) of 9.38%.(1) Furthermore .
- Trial name
- NCT05061615
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
Acne
Management of Side-Effects of Anti-Acne Treatment by a Cosmetic Routine
Retinoid-based topical acne treatment may induce local tolerance issues such as erythema, dryness, stinging and burning sensations that may reduce adherence and efficacy.
- Trial name
- NCT05486910
- Where
- Poland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Acne Vulgaris
A Safety, Tolerability and Preliminary Efficacy Study of DRM01B Topical Gel
This is a Phase 1/2a study. The purpose of Phase 1 was to evaluate the safety and tolerability of DRM01B Topical Gel in 6 healthy volunteers.
- Trial name
- NCT01936324
- Testing
- Olumacostat Glasaretil Gel, 7.5%, Olumacostat Glasaretil Gel, Vehicle
- Where
- 12 sites in Canada
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Dermira, Inc.
Acne
Efficacy and Safety of CD5024 1% in Acne Vulgaris
Exploratory, multi-center, randomised, investigator-blinded, vehicle controlled study using intra-individual comparison involving subjects with acne vulgaris on face to evaluate the efficacy of CD5024 1% cream over a 6-week…
- Trial name
- NCT03034460
- Testing
- CD5024 1% cream, CD0271/CD1579 gel
- Where
- 7 sites in Canada, France and 1 more
- Volunteers
- 70 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Evaluation of Irritation That Potentially Could be Caused by Two Facial Gels Applied to Opposite Sides of the Face
A study to compare the skin irritation potential of two marketed gels for acne treatment, each applied to half of the face of healthy volunteers.
- Trial name
- NCT00952523
- Testing
- Tretinoin Facial Gel, Adapalene/Benzoyl Peroxide Facial Gel
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Acne Vulgaris
Photodynamic Therapy of Acne Vulgaris - a Randomized Blinded Controlled Study
The purpose of the study is to evaluated the efficacy and tolerability of methyl aminolevulinate and 5-aminolevulinic acid photodynamic therapy in patients with moderate to severe facial acne vulgaris in a randomized controlled…
- Trial name
- NCT00206895
- Testing
- Photodynamic therapy
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Bispebjerg Hospital
Acne Vulgaris
Study STF115287, a Clinical Confirmation Study of GSK2585823 in the Treatment of Acne Vulgaris in Japanese Subjects
This is a multicenter, randomized, single-blinded (investigator's blinded), active-controlled (clindamycin [CLDM] 1% gel), parallel-group study in Japanese subjects with acne vulgaris to demonstrate the efficacy of GSK2585823…
- Trial name
- NCT01445301
- Testing
- GSK2585823(CLDM 1%-BPO 3% gel), CLDM 1% gel twice daily
- Where
- 26 sites in Japan
- Volunteers
- 800 people
- Sponsor
- GlaxoSmithKline
Chronic Spontaneous Urticaria (CSU), Hidradenitis Suppurativa (HS)
SKIN Disease Profiling by an Exploratory, pRospective, Biomarker Study in dermatoloGY Practice (SKINERGY)
The goal of this observational study is to comprehensively profile six immune-mediated inflammatory diseases, including atopic dermatitis (AD), plaque psoriasis (PSO), hidradenitis suppurativa (HS), cutaneous T-cell lymphoma…
- Conditions
- Chronic Spontaneous Urticaria (CSU), Hidradenitis Suppurativa (HS), Psoriasis (PsO), Atopic Dermatitis (AD)
- Trial name
- SKINERGY (NCT07021495)
- Where
- 8 sites in Netherlands
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Acne Vulgaris
Comparative Study of Metformin Versus Doxycycline in Moderate to Severe Adult Acne Vulgaris Patients.
The goal of this clinical trial is to compare the effect of doxycycline and metformin in treatment of acne vulgaris patients. The main question is aimed to answer is whether metformin is more effective than doxycycline in…
- Trial name
- NCT06252194
- Testing
- Metformin and doxycycline
- Where
- Bangladesh
- Volunteers
- 120 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Acne Vulgaris
Oral Baidi Quzhi Granule Combined With Ju Ying Cream for Acne Vulgaris
We designed the study as a double-blind,randomized,controlled clinical trial.The aim of this trial is to clarify the treatment efficacy, safety, and recurrence control of BaiDi QuZhi(BDQZ) granule combined with Ju Yin(JY) cream…
- Trial name
- NCT05035979
- Testing
- BaidI Quzhi granule, Ju Yin cream
- Volunteers
- 472 people
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Acne Vulgaris
Placebo Controlled Efficacy and Safety Study of CD2475/101 40 mg Tablets vs. Placebo and Doxycycline 100 mg Capsules Once Daily in the Treatment of Inflammatory Lesions of Acne Vulgaris
The primary objectives of the study is to show CD2475/101 40mg tablets taken once a day for 16 weeks is superior to the placebo in Change from baseline to Week 16(Last Observation Carry Forward, Intent To Treat) in inflammatory…
- Trial name
- NCT01320033
- Testing
- CD2475/101 40 mg, Doxycycline 100 mg
- Where
- 31 sites in United States
- Volunteers
- 662 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Randomized, Triple-Blind, Vehicle-Controlled Trial of Topical Dapsone Gel 7.5% in Patients With Acne Vulgaris
The goal of this randomized, triple-blind, vehicle-controlled clinical trial is to evaluate whether topical 7.5% dapsone gel is effective for treating mild-to-moderate acne vulgaris in adults.
- Trial name
- NCT07244887
- Testing
- Dapsone 7.5% gel, Vehicle gel
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Oya Helin Dundar
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