Clinical trials: acne
Acne Vulgaris
EGCG Improves Acne by Modulating Molecular Targets
Epigallocatechin-3-gallate (EGCG) may improve acne vulgaris major polyphenolic constituent in green tea known as potent anti-carcinogenic, anti-inflammatory, anti-proliferative, and antimicrobial activities lipid-lowering and…
- Trial name
- EGCG (NCT01687556)
- Testing
- topical EGCG application on acne
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Seoul National University Hospital
Non-Cystic Acne
A Study to Evaluate the Efficacy and Safety of Clear Skin Formula on Mitigating Mild to Moderate Non-cystic Acne
The goal of this clinical trial is to compare Clear Skin Fomula Supplement to Placebo in healthy men and women ages 18-40 to mitigate mild to moderate non-cystic acne over the course of 12 weeks.
- Trial name
- NCT05879406
- Testing
- VitaMedica® Clear Skin Formula capsules
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ablon Skin Institute Research Center
Acne Scarring
Safety and Efficacy of the 4MD Micro Needling Device in the Treatment of Acne Scars
The objective of this post market clinical follow-up study is to assess the safety and effectiveness of the 4MD microneedling device in reducing scarring of atrophic acne scars.
- Trial name
- NCT05386732
- Testing
- Micro needling
- Where
- Spain
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Dermapenworld
Acne Vulgaris
De Novo Lipogenesis of Sebaceous Glands in Acne
There are two purposes of this study: 1. First, the investigators want to see what the differences are in de novo sebaceous lipid production of people with and without acne. 2.
- Trial name
- NCT02620813
- Testing
- Tretinoin, Isotretinoin
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Acne Vulgaris
Effectivity and Safety of Combination Cream of Salicylic Acid, Aqua Posae Filiformis, Niacinamide, Lipohydroxy Acid, Procerad and Zinc PCA
This clinical study will compare the effectivity and safety of combination cream of Salicylic Acid, Aqua Posae Filiformis, Niacinamide, Lipohydroxy Acid, Procerad, and Zinc PCA as adjuvant therapy for acne vulgaris patients.
- Trial name
- NCT05497323
- Testing
- Combination Cream, Adapalene 0,1% cream
- Where
- 5 sites in Indonesia
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Dr.dr.Irma Bernadette, SpKK (K)
Acne Vulgaris
Safety and Efficacy of Tazarotene Cream 0.1% Compared With Adapalene Gel 0.3% in the Treatment of Moderate to Severe Facial Acne Vulgaris
Comparison of the safety and efficacy of Tazarotene Cream 0.1% compared with Adapalene Gel 0.3% in treating moderate to severe facial acne vulgaris
- Trial name
- NCT00829049
- Testing
- Tazarotene Cream 0.1%, Adapalene
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Allergan
Acne Vulgaris
A Bioavailability Study of DFD-03 Compared to Tazorac® in Patients With Moderate Acne Vulgaris
This was a multicenter, randomized, multiple-dose, laboratory-blinded, open-label, 2-arm, parallel-arm study in subjects with moderate acne vulgaris.
- Trial name
- NCT03599193
- Testing
- Tazarotene Lotion, 0.1%, Tazarotene Cream, 0.1%
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Acne Vulgaris
A Study Comparing Trifarotene Cream 0.005% to AKLIEF® CREAM (US REFERENCE LISTED DRUG), AKLIEF™ CREAM (CANADIAN REFERENCE PRODUCT) in the Treatment of Acne Vulgaris
To demonstrate the efficacy, therapeutic equivalence and safety of Trifarotene Cream 0.005% (Taro Pharmaceuticals U.S.A., Inc.) and US Reference Listed Drug, Canadian Reference Product over the placebo control in the treatment of…
- Trial name
- NCT06733402
- Testing
- Trifarotene Cream 0.005%, AKLIEF® Cream (Trifarotene 0.005%) US REFERENCE LISTED DRUG, AKLIEF® Cream (Trifarotene 50 mcg/g) CANADIAN REFERENCE PRODUCT
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Acne Scar
TheTreatment of Acne Scar Using UltraPulse CO2 Laser
Purpose of the study is to assess the effect and evaluate topographic volume changes of UltraPulse at treating boxcar scars with different energy and the effect of UltraPulse at treating icepick scars.
- Trial name
- NCT04648995
- Testing
- High energy (UltraPulse), Low energy (UltraPulse)
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Haute Beauté Skin & Vein Clinic
Acne Rosacea
Determine the Effect of Administering Periostat(R) Twice Daily on Patients With Acne Rosacea
The purpose of this study is to determine whether Periostat(R), Doxycycline Hyclate 20 mg Tablets, taken twice daily is effective in reducing the red and white heads and overall redness associated with rosacea.
- Trial name
- NCT00041977
- Testing
- doxycycline hyclate 20 mg twice daily
- Where
- 7 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- CollaGenex Pharmaceuticals
Acne Vulgaris
Gene Polymorphisms, Skin Barrier, and Inflammation in Acne
This study investigated the relationship between Matrix Metalloproteinase-2 (MMP-2) and Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) gene polymorphisms and acne pathogenesis.
- Trial name
- NCT07069075
- Testing
- MMP-2 Gene Polymorphism (rs243865) Analysis, TIMP-2 Gene Polymorphism (rs8179090) Analysis
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hong Zhang
Acne
Safety, Tolerability, and Clinical Effectiveness of Adapalene/Clindamycin Phosphate Gel (Klenzit®-C) in Vietnamese Patients With Mild to Moderate Acne Vulgaris
The CLEAN ACNE Study is a prospective, observational, Phase IV, open-label, multicenter, single-arm study at 3-5 sites in Vietnam.
- Trial name
- Clean Acne (NCT07918001)
- Testing
- Klenzit®-C (Adapalene/Clindamycin Phosphate Gel)
- Where
- 3 sites in Vietnam
- Volunteers
- 225 people
- Sponsor
- IR INNOVATE RESEARCH PRIVATE LIMITED
Osteoarthritis
Can Addition of Doxycycline Perioperatively Reduce Propionibacterium Acnes in Shoulder Arthroplasty?
The purpose of this study is to investigate antibiotic treatment to target bacteria about the shoulder. This bacteria, Propionibacterium acnes, is detected in many revision shoulder surgeries and is thought to contribute to…
- Trial name
- NCT03115177
- Testing
- Doxycycline, Cefazolin
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Rush University Medical Center
Acne Vulgaris
Comparing Sarecycline and Doxycycline Effects on the Skin and Gut Bacteria in Acne.
This study is being done to help better understand how the gut and skin bacteria of the body change when people with acne are treated with Sarecycline or Doxycycline.
- Trial name
- NCT07544251
- Testing
- Sarecycline, Doxycycline
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Acne Vulgaris
Adherence to Study Medication Compared to Generic Topical Clindamycin Plus Generic Topical Tretinoin in Subjects With Mild to Moderate Acne Vulgaris
The purpose of this research study is to evaluate the effectiveness of two different types of topical acne medication. This study will help to determine if one combined medication results in better acne improvement than two…
- Trial name
- NCT01047189
- Testing
- clindamycin phosphate 1.2% and tretinoin 0.025%, clindamycin 1% gel, tretinoin 0.025% cream
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Wake Forest University
Inflammatory Acne
Study to Assess the Efficacy and Safety of LYS006 in Patients With Moderate to Severe Inflammatory Acne
The main purpose of this study is to assess preliminary efficacy and safety of LYS006 in patients with moderate to severe inflammatory acne and to determine if LYS006 has an adequate clinical profile for further clinical…
- Trial name
- NCT03497897
- Testing
- LYS006 20 mg, LYS006 2 mg
- Where
- 17 sites in United States, Czechia and 4 more
- Volunteers
- 66 people
- Sponsor
- Novartis Pharmaceuticals
Acne, Melasma
The Use of Image-Based Computer Gradings in the Analysis of Acne, Rosacea, Melasma, and Seborrheic Dermatitis
The study is conducted to determine if image-based computer grading can of acne, melasma, rosacea and seborrheic dermatitis correlate well to expert based clinical severity grading.
- Conditions
- Acne, Melasma, Rosacea, Seborrheic Dermatitis
- Trial name
- NCT05942248
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Hidradenitis Suppurativa
An Alternative Dose Interval Study in Participants With Hidradenitis Suppurativa Receiving Brodalumab
Phase 0 Study of an alternative dosing interval of Brodalumab in patients with moderate to severe Hidradenitis Suppurativa to identify biomarkers of disease activity and clinical response.
- Trial name
- NCT04249713
- Testing
- Brodalumab
- Where
- United States
- Sponsor
- Rockefeller University
Acne
A Pilot Clinical Trial Investigating the Effect of Cutaneous Cooling on Sebum Production
To evaluate the safety and feasibility of reducing human sebum production using the ZELTIQ System.
- Trial name
- NCT01686841
- Testing
- The Zeltiq System
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Acne Vulgaris
The Treatment of Acne Vulgaris With Radiofrequency Device
Radiofrequency emmitting device, normaly used for thermage treatments will be used on 22 mild to moderate acne patients faces. The aim of the study is to check whether RF heating of subcutaneous and dermis will improve acne in…
- Trial name
- NCT00441805
- Testing
- Radio Frequency
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Alma Lasers
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.