Clinical trials: acne
SAPHO Syndrome
Characterizing SAPHO With 68Ga-FAPI PET/CT
68Ga-FAPI has been developed as a tumor-targeting agent as fibroblast activation protein is overexpressed in cancer-associated fibroblasts and some inflammation.
- Trial name
- NCT04596462
- Testing
- 68Ga-FAPI
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Peking Union Medical College Hospital
Acne Vulgaris
Open-Label, Randomized Study Evaluating the Absorption and Systemic Pharmacokinetics of Topically Applied IDP-126 Gel in Comparison With Control Gel
This will be an open-label study designed to assess the safety and plasma PK of topically applied IDP-126 Gel compared to Control Gel.
- Trial name
- NCT03653403
- Testing
- IDP-126 Gel, Control Gel
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Bausch Health Americas, Inc.
Acne Scars - Mixed Atrophic and Hypertrophic
Performance of PicoWayTM Picosecond Fractional Laser for Acne Scars
Open-label, prospective study. Up to 60 healthy adult volunteers seeking facial acne scars treatment, males or females of 18 to 75 years of age, from up to 3 investigational sites.
- Trial name
- NCT02592993
- Testing
- PicoWay device
- Where
- 3 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Acne Vulgaris
Six Months Evaluation of Next Science Acne Creams on Facial Acne in Adult Females.
To assess facial acne vulgaris clinical and psychological outcomes by measuring differences in lesions counts, investigator global assessment, and subjects quality of life scores over 6 months in adult females treated with Next…
- Trial name
- NCT03106766
- Testing
- Acne cream 2X, Acne cream 1X
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Next Science TM
Acne Vulgaris
Efficacy of Azadirachta Indica (Homoeopathic Medicine) in Treatment of Acne Vulgaris
Acne is one of the most common skin problems in teenagers and adolescents. There are many lesser known homoeopathic medicines which have been mentioned in the literature for treatment of acne but their potential has not been…
- Trial name
- NCT01321645
- Testing
- Azadirachta Indica
- Where
- India
- Volunteers
- 31 people
- Sponsor
- Miglani, Anjali
Atrophic Acne Scar
Fractional CO₂ Laser Combined With Topical Plant-Derived Exosomes Versus Non-Cross-Linked Hyaluronic Acid for Atrophic Acne Scars
Fractional CO₂ laser combined with topical exosomes and non-cross-linked hyaluronic acid both improve atrophic acne scars, but direct comparative evidence between these adjunctive therapies has been limited.
- Trial name
- NCT07868445
- Testing
- Fractional co2 laser, Exosomes, Hyaluronic Acid skin booster
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- October 6 University
Mild to Moderate Acne, Stiffness of Joint, Nec, Involving Ankle and Foot in MDR24_1
A Proof of Science, Dose-Response Study to Evaluate the Safety, Efficacy of Different Dosages of Test Treatments
A proof of science clinical study with randomized, four-arm, comparative, single-blind, within the arm - Dose-Response Study to evaluate the safety and efficacy of different collagen peptide-containing test treatments in adult…
- Conditions
- Mild to Moderate Acne, Stiffness of Joint, Nec, Involving Ankle and Foot in MDR24_1, Other Specified Diseases of Hair and Hair Follicles, Brittle Nails
- Trial name
- NCT05613660
- Testing
- Veg Collagen Peptide, Bovine Collagen Peptide, Fish | Marine Collagen Peptide
- Where
- India
- Volunteers
- 264 people
- Sponsor
- NovoBliss Research Pvt Ltd
Acne Rosacea
DMT310-005 Topical in the Treatment of Acne Rosacea
The objective is to evaluate the tolerability, safety, and efficacy of DMT310 topical powder mixed with diluent in male and female patients with moderate to severe facial acne rosacea.
- Trial name
- NCT05108025
- Testing
- Topical Powder
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Dermata Therapeutics
Acne Vulgaris
Oral Probiotics on the Microbiome and Lipidome in Acne Vulgaris
The purpose of this study is to determine how probiotics affect sebum production and gut health in those with acne vulgaris.
- Trial name
- NCT04596748
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Acne Vulgaris
Double-Blind, Placebo-Controlled Study to Evaluate 3 Doses of a Novel Tetracycline in the Treatment of Facial Acne Vulgaris
To evaluate the safety and effectiveness of 3 strengths of P005672-HCl compared to placebo for the treatment of moderate to severe facial acne vulgaris.
- Trial name
- NCT01628549
- Testing
- 50 mg P005672-HCl, 100 mg P005672-HCl
- Where
- 38 sites in United States
- Volunteers
- 285 people
- Sponsor
- Almirall, S.A.
Acne Vulgaris
A Comparative Study of the Tolerability of Two Combination Therapies for the Treatment of Acne
The purpose of this study is to compare the tolerability of topical combination therapies in the treatment of facial acne.
- Trial name
- NCT00887484
- Testing
- BENZOYL PEROXIDE/ CLINDAMYCIN, BENZOYL PEROXIDE/ ADAPALENE
- Where
- 4 sites in Argentina
- Volunteers
- 50 people
- Sponsor
- Stiefel, a GSK Company
Helicobacter Pylori Infection, Acne Vulgaris
Prevalence of H.Pylori in Patients With Acne Vulgaris Acne Vulgaris
The objective of the study is to investigate prevalence of H.Pylori infection among acne vulgaris patients.
- Trial name
- NCT03411733
- Testing
- Blood and stool samples collection
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sohag University
Mild to Moderate Acne
Safety and Efficacy Comparison of Minocycline Microgranules Versus Lymecycline in the Treatment of Mild to Moderate Acne
This is a clinical trial to compare the benefits and possible adverse events of two antibiotic treatments for mild to moderate acne.
- Trial name
- MXMIN-001 (NCT00988026)
- Testing
- Minocycline vs Lymecycline
- Where
- Mexico
- Volunteers
- 168 people
- Sponsor
- Darier
Acne Vulgaris
A Long-term Safety and Efficacy Study of N-Acetyl-GED-0507-34-LEVO Gel 5%, in Subjects With Acne Vulgaris (GEDACNE-LT)
The clinical trial aims to test the long term safety of a new drug for acne vulgaris. The trial is performed to answer this question "Is it safe to apply the IMP daily for up to 52 weeks?".
- Trial name
- GEDACNE-LT (NCT07389109)
- Testing
- N-Acetyl-GED-0507-34-LEVO gel 5%
- Where
- 59 sites in Italy, Poland and 1 more
- Volunteers
- 400 people
- Sponsor
- PPM Services S.A.
Acne Vulgaris
Application of Poly-herbal Powder for Treating Acne Vulgaris
Acne is a common problem in adolescence to young adult. But there is no such remedy available for acne treatment which has no side effects.
- Trial name
- NCT04949932
- Testing
- Mixed powder of Lens culinaris, Curcuma longa, Mentha arvensis, Azadirachta indica, and Trigonella foenumgraecum., Cicer arietinum powder
- Where
- Bangladesh
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Dr. Md. Shahab Uddin
Acne
Apremilast in the Treatment of Moderate to Severe Acne
Acne is a chronic inflammatory disease of the pilosebaceous unit that affects 80-90% of the population, especially teenagers, although adult acne is a significant problem for 3-6 % of adult men and 5-12% of adult women.
- Trial name
- NCT01074502
- Testing
- apremilast
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Hyperpigmentation
Efficacy and Tolerability of the Tested Formula After 3 Months of Treatment of Facial Hyperpigmentation of 3 Origins
The objective of this study is to evaluate the efficacy, cosmetic acceptability and improvement of the stigmatization of the tested product (2039125 03) used bis in die (BID) for 3 months in adult patients suffering from mild to…
- Trial name
- NCT06234527
- Testing
- tested product
- Where
- Senegal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Acne Vulgaris
A Long-term Safety Study of Olumacostat Glasaretil Gel in Subjects With Acne Vulgaris
The objective of this study is to assess the long-term safety of Olumacostat Glasaretil gel, 5.0% in patients with acne vulgaris
- Trial name
- NCT03127956
- Testing
- Olumacostat Glasaretil Gel, 5.0%
- Where
- 94 sites in United States, Australia and 1 more
- Volunteers
- 748 people
- Sponsor
- Dermira, Inc.
Acne Vulgaris
Efficacy of Handheld Acne Heat Device
The aim of our study is to determine the time to resolution of individual acne lesions using a popular handheld heat based device in comparison to no treatment and to standard topical therapy with benzoyl peroxide in order to…
- Trial name
- NCT01613924
- Testing
- Split face: handheld acne heat based device (Zeno Hot Spot) and no treatment, Split face: handheld acne heat based device, Zeno Hot Spot, and topical benzoyl peroxide 4%
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of British Columbia
Atopic Dermatitis, Acne
Electrochemistry Measurement of Skin Hydration Parameters
To date measuring the effect of dermocosmetic products on the main identified factors of aging and alteration of the skin barrier is based on invasive and expensive experiments.
- Conditions
- Atopic Dermatitis, Acne, Skin Electrochemistry
- Trial name
- SKINBIOSENSE (NCT05071456)
- Testing
- Collects of skin's hydration
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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