Clinical trials: acne
Acne
Bioequivalence Study of Tretinoin Gel 0.05% to Brand Tretinoin Gel
This was a double-blind, randomized, three-treatment, parallel study. Normal, healthy male and female children and adults (i.e., ages 12 to 40 years) with at least Grade 2 (i.e., mild severity) acne vulgaris were treated on the…
- Trial name
- NCT02249767
- Testing
- Tretinoin
- Volunteers
- 574 people, healthy volunteers welcome
- Sponsor
- Spear Pharmaceuticals
Acne Vulgaris
Compare the Tolerance of Clindamycin 1% /Benzoyl Peroxide (BPO) 5% Gel to Clindamycin 1.2%/ BPO 2.5% Topical Medications
This is a single-blind (blinded expert grader) study that will enroll 25-30 healthy volunteers without facial acne. On 1 side of the face, the subject will apply 1 of the 2 test products, clindamycin and benzoyl peroxide 5% or…
- Trial name
- NCT01015638
- Testing
- Clindamycin and BPO 5% gel, Clindamycin phosphate and benzoyl peroxide 2.5% gel.
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Stiefel, a GSK Company
Acne
Study of the Use of Low Level Laser Therapy to Reduce Acne
The purpose of this study is to determine whether low level laser light therapy is effective in the treatment of acne blemishes.
- Trial name
- NCT01276535
- Testing
- Erchonia MLS + Erchonia THL
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Erchonia Corporation
Acne Vulgaris
A Study to Evaluate the Reduction in Sebum (Skin Oil) Induced by Clascoterone Cream 1% in Acne Patients
The etiology of acne is heavily dependent on the production of sebum by the sebaceous glands that results in the growth of the bacteria c. acnes. If no sebum is present, there is no nutritional source for the c.
- Trial name
- NCT06415279
- Testing
- Winlevi (clascoterone) 1% cream
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Sun Pharmaceutical Industries Limited
Atrophic Acne Scarring
The Use of Bellafill for Atrophic Acne Scar Correction in the Full Facial Area
This is an open-label, multicenter, prospective pilot study assessing the efficacy and safety of Bellafill for correction of distensible atrophic acne scars in the full facial area.
- Trial name
- NCT02642627
- Testing
- Bellafill
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Suneva Medical, Inc.
Acne Vulgaris
Efficacy and Safety Study of 2 Different Concentrations of CD1579 Gels Versus Vehicle in the Treatment of Acne Vulgaris.
This study is to assess the efficacy and safety of two concentrations of CD1579 (2.5% and 5%) versus vehicle in the treatment of acne vulgaris in the Japanese patients.
- Trial name
- NCT02073461
- Testing
- CD1579 2.5%, CD1579 5%, Vehicle
- Where
- 6 sites in Japan
- Volunteers
- 236 people
- Sponsor
- Galderma R&D
Acne Vulgaris
Aczone Gel 7.5% in the Treatment of Acne Vulgaris in Patients With Skin of Color
Acne vulgaris is a common skin disease characterized by inflammatory papules, pustules, and comedones that is prevalent in men and women of color.
- Trial name
- NCT03681470
- Testing
- Aczone Gel
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Acne
Efficacy and Safety of Aczone 7.5% Gel in the Treatment of Truncal Acne Vulgaris
To determine if Dapsone (Aczone) 7.5% gel is a safe and effective treatment for acne on the trunk
- Trial name
- NCT02944461
- Testing
- Dapsone 7.5 % gel
- Where
- 3 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Derm Research, PLLC
Acne Vulgaris
A Study Evaluating the Efficacy and Safety of Clascoterone Cream 1% in Skin of Color Patients With Acne
Acne vulgaris is the most common skin disease in patients with skin of color and second most common in Caucasian population. The global prevalence is thought to be as high as 60-80% in individuals 12-25 years of age.
- Trial name
- NCT06415305
- Testing
- Winlevi (clascoterone) 1% cream
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Sun Pharmaceutical Industries Limited
Acne
Adapalene BPO Gel Pump, Moisturizer SPF 30 and Foam Wash in Patients With Mild to Moderate Acne Vulgaris
This is an open-label, multi-center study to be conducted in the United States. The study will examine the change in lesion count in subjects using Epiduo® Gel Pump (once daily) in conjunction with Cetaphil® DermaControl™ Foam…
- Trial name
- NCT01951417
- Testing
- Adapalene/BPO Gel, Moisturizer SPF 30, Foam Wash
- Where
- 5 sites in United States
- Volunteers
- 81 people
- Sponsor
- Galderma R&D
Acne Vulgaris
"Clinical Trial to Determine the Efficacy of Vitamin D for Acne Therapy"
The purpose of this study is to study the effects of topical Vitamin D cream (Calcipotriene, also known as Dovonex) on acne. The information gained from this study may lead to new treatments for acne.
- Trial name
- NCT01694433
- Testing
- Calcipotriene
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Atrophic Acne Scars
A Pilot Study to Evaluate the Safety and Effectiveness of Microneedling and Bellafill to Treat Facial Acne Scars
This is an open-label, randomized, multicenter, prospective trial assessing the efficacy and safety of microneedling treatment alone vs.
- Trial name
- NCT02643628
- Testing
- Microneedling, Microneedling followed by Bellafill treatment
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Suneva Medical, Inc.
Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver Disease
Metformin for Ectopic Fat Deposition and Metabolic Markers in Polycystic Ovary Syndrome (PCOS)
This project, "A double-blind placebo-controlled randomized clinical trial assessing the efficacy of metformin for hepatic fat in adolescents and young adults with polycystic ovary syndrome", proposes exploring the use of novel…
- Conditions
- Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver Disease, Metabolic Syndrome
- Trial name
- NCT02500147
- Testing
- Metformin
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Columbia University
Acne Vulgaris
Subject Reported Outcomes With Use of Adapalene 0.3% - Benzoyl Peroxide (BPO) 2.5% in Dark Skin Acne
This is a multicenter open-label, prospective study in subjects with dark skin from one of the 3 ethnic/race backgrounds: Asian, Latin American and Black/African-American and with moderate to severe acne vulgaris on the face.
- Trial name
- EDeN (NCT02932267)
- Testing
- Adapalene 0.3% / BPO 2.5% gel
- Where
- 3 sites in United States, Mauritius and 1 more
- Volunteers
- 50 people
- Sponsor
- Galderma R&D
Acne Vulgaris
A Study That Evaluates the Decrease in Irritation When Using Additional Acne Treatment Products
This study is to see if there's any difference in the amount of facial irritation when two acne products are used together on one side of the face, compared to one acne treatment product used alone on the other side of the face.
- Trial name
- NCT01313728
- Testing
- Dapsone plus Tretinoin Gel, Tretinoin Gel
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Acne Vulgaris
A Phase 2 Dose Escalating Study to Evaluate the Safety and Efficacy of CB-03-01 Cream in Subjects With Facial Acne Vulgaris
CB-03-01 is being developed for the topical treatment of acne vulgaris, an androgen-dependent skin disorder. The purpose of this study is to compare the safety and efficacy of multiple concentrations of CB-03-01 to vehicle in the…
- Trial name
- NCT01631474
- Testing
- CB-03-01, Vehicle
- Where
- 13 sites in United States
- Volunteers
- 363 people
- Sponsor
- Intrepid Therapeutics, Inc.
Acne Vulgaris
A Study to Evaluate Tolerability of Two Topical Drug Products in the Treatment of Facial Acne
Multi-center, single-blind, randomized, comparative, split-face study. The duration of the study is 8 weeks. Commencing at baseline, subjects will apply once daily both clindamycin and benzoyl peroxide gel and benzoyl…
- Trial name
- NCT00964223
- Testing
- Clindamycin and benzoyl peroxide gel (Duac® Topical Gel), benzoyl peroxide and adapalene gel (EPIDUO™ Gel)
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Stiefel, a GSK Company
Acne Vulgaris
A Study of S6G5T3 in the Treatment of Acne Vulgaris
To assess the efficacy of S6G5T-3 compared to its vehicle when applied once daily for 12 weeks in participants with acne vulgaris.
- Trial name
- NCT03761810
- Testing
- S6G5T-3, S6G5T-8
- Where
- United States
- Volunteers
- 434 people
- Sponsor
- Sol-Gel Technologies, Ltd.
Acne Vulgaris
Dapsone Gel 5% and Tazarotene Cream 0.1% Versus Tazarotene Cream 0.1% Monotherapy for Facial Acne Vulgaris
A 12-week evaluation of the safety and efficacy of dapsone gel 5% when used with tazarotene cream 0.1% compared with tazarotene cream 0.1% monotherapy in treating moderate to severe facial acne vulgaris
- Trial name
- NCT00834210
- Testing
- Dapsone, Tazarotene
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- Allergan
Acne Vulgaris
A Study to Compare the Efficacy and Safety of Topical Administration of FMX-101 for Treatment of Moderate-to-Severe Acne
This is a Phase 3 study to evaluate the efficacy, safety and long-term safety of the topical administration of FMX-101, 4% minocycline foam for the treatment of moderate-to-severe acne vulgaris.
- Trial name
- NCT02815267
- Testing
- FMX-101, 4% minocycline foam, Vehicle Foam
- Where
- 31 sites in United States, Dominican Republic
- Volunteers
- 466 people
- Sponsor
- Vyne Therapeutics Inc.