Clinical trials: and Renal Recovery
Childhood Choroid Plexus Tumor, Childhood Medulloblastoma
Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer
This randomized phase III trial studies flexible administration of filgrastim after combination chemotherapy to see how well it works compared to fixed administration of filgrastim in decreasing side effects of chemotherapy in…
- Conditions
- Childhood Choroid Plexus Tumor, Childhood Medulloblastoma, Childhood Pineoblastoma, Childhood Soft Tissue Sarcoma
- Trial name
- NCT01987596
- Testing
- filgrastim
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Kidney Transplantation, Acute Kidney Tubular Necrosis
Effect of BM-MSCs in DCD Kidney Transplantation
This study is designed to determine the efficacy and safety of allogeneic bone marrow-derived mesenchymal stem cells in kidney transplantation from Chinese donation after citizen's death (DCD).
- Trial name
- NCT02561767
- Testing
- bone marrow-derived mesenchymal stem cells, Saline, Induction therapy (ATG or Basiliximab)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
End Stage Renal Disease, AV Fistula
Safety and Efficacy Study of the Venous Window Needle Guide to Access Arteriovenous (AV)Fistulae
The SAVE Study will evaluate the safety and efficacy of the Venous Window Needle Guide in achieving access of a deep, un-cannulatable arteriovenous fistula to complete hemodialysis as prescribed.
- Conditions
- End Stage Renal Disease, AV Fistula, Kidney Failure
- Trial name
- SAVE (NCT01471041)
- Testing
- Venous Window Needle Guide
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- Vital Access Corp.
Acute Kidney Disease, Acute Kidney Injury
Impact of Different CRRT Modalities, Dosing Strategies, and Timing on Kidney Recovery and Prolonged Kidney Dysfunction
KARMA study is a hospital-based research study looking at how different ways of delivering kidney support therapy (CRRT) affect patients who are critically ill.
- Trial name
- KARMA (NCT07052617)
- Testing
- Continuos renal replacement therapy
- Volunteers
- 2,500 people
- Sponsor
- Croatian Society for Organ Support
Terminal Renal Insufficiency
Describe the Effect of the Optimized Hemodialysis Technique (HDx) With Medium Cut-Off Membrane on Recovery Time and Quality of Life
In this study, the effect of optimizing the dialytic technique using simple questionnaires carried out in clinical routine will be described.
- Trial name
- EHDXTRQV (NCT05689801)
- Testing
- Questionnaire "recovery time after a dialysis session"., SF-12 questionnaire, EQ-5D-5L Questionnaire
- Where
- France
- Volunteers
- 18 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Renal Tumor
A Comparison of Nefopam-propacetamol Combination and Propacetamol for Postoperative Quality of Recovery After Laparoscopic Nephrectomy
The multimodal analgesia for postoperative pain aims for optimal analgesia through additive or synergic drug effects. The multimodal analgesia results in the use of smaller doses of opioids and lowering opioid-related side…
- Trial name
- NCT01833728
- Testing
- nefopam-propacetamol combination, propacetamol alone
- Where
- South Korea
- Volunteers
- 16 people
- Sponsor
- Yonsei University
Acute Kidney Injury
Non-recovery of Kidney Function After AKI
One in five patients admitted to hospital suffer a sudden reduction in kidney function, termed acute kidney injury (AKI). Rather than kidney 'injury' being caused by physical trauma, the term describes reversible damage caused by…
- Trial name
- RECOVER-AKI (NCT05014022)
- Testing
- Multiparametric renal MRI
- Volunteers
- 50 people
- Sponsor
- University of Nottingham
Cardiorenal Syndrome
Dobutamaine Versus Milrinone in Cardiorenal Syndrome
Heart failure is recognized as one of the most common indications for hospitalization amongst adults aged >65 years in United States with estimated Medicare cost to be 17 billion or more.
- Trial name
- DOMICAS (NCT02644057)
- Testing
- Milrinone, Dobutamine
- Where
- United States
- Sponsor
- Maimonides Medical Center
Advanced Renal Cell Carcinoma
Study of Front Line Therapy With Nivolumab and Salvage Nivolumab + Ipilimumab in Patients With Advanced Renal Cell Carcinoma
Phase II trial of nivolumab in 120 treatment naïve patients with ccRCC.
- Trial name
- NCT03117309
- Testing
- Nivolumab 240 mg, Ipilimumab 1mg/kg, Nivolumab 3mg/kg
- Where
- 12 sites in United States
- Volunteers
- 164 people
- Sponsor
- Michael B. Atkins, MD
Acute Kidney Injury
Automated Peritoneal Dialysis Versus Intermittent Hemodialysis in Acute Kidney Injury
This is a multi-center randomized clinical trial study. The purpose of this study is to examine safety, feasibility and efficacy of automated peritoneal dialysis as compared with intermittent hemodialysis for AKI patients with…
- Trial name
- SAFE-APD (NCT03598387)
- Testing
- Automated peritoneal dialysis, Intermittent hemodialysis
- Where
- 5 sites in China
- Volunteers
- 100 people
- Sponsor
- Limeng Chen
Acute Kidney Injury
Recovery After Dialysis-Requiring Acute Kidney Injury
The Recovery After Dialysis-Requiring Acute Kidney Injury (RAD-AKI) Pilot Study is a 2-arm randomized clinical trial of hospitalized patients with dialysis-requiring acute kidney injury (RAD-AKI), comparing conventional…
- Trial name
- RAD-AKI (NCT03305549)
- Testing
- Conservative dialysis strategy, TIW dialysis strategy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of California, San Francisco
Brain Metastases
Hippocampal Sparing Whole Brain Radiation Versus Stereotactic Radiation in Patients With 5-20 Brain Metastases: A Phase III, Randomized Trial
This research study is studying two different types of radiation as treatment for brain metastases (tumors in the brain that spread from a cancer that originated elsewhere in the body)
- Trial name
- NCT03075072
- Testing
- Whole brain radiation, Stereotactic radiation (SRS)
- Where
- 2 sites in United States
- Volunteers
- 196 people
- Sponsor
- Brigham and Women's Hospital
Renal Insufficiency, Acute, Renal Replacement Therapy
Intermittent Versus Continuous Renal Replacement Therapy for Acute Renal Failure
This multicentre SHARF4 (Stuivenberg Hospital Acute Renal Failure) study aims to investigate outcome in patients with acute renal failure (ARF), stratified according to severity of disease (SHARF score) and randomised to…
- Trial name
- NCT00322933
- Testing
- renal replacement therapy (intermittent or continuous)
- Where
- Belgium
- Volunteers
- 1,628 people
- Sponsor
- Ziekenhuis Netwerk Antwerpen (ZNA)
Acute Renal Failure, Acute Kidney Tubular Necrosis
Predictive Value of PIIINP and Urinary NGAL in Renal Function Recovery
Acute Renal Failure (ARF) is defined by a severe, and usually reversible, glomerular filtration rate decreasing. Acute Tubular Necrosis (ATN) remain the major cause of ARF involving distress and destruction of tubular cells.
- Conditions
- Acute Renal Failure, Acute Kidney Tubular Necrosis, Chronic Kidney Failure
- Trial name
- PIIINP-NGAL (NCT02889575)
- Where
- France
- Volunteers
- 287 people
- Sponsor
- Nantes University Hospital
Living Liver and Kidney Donors
Living Organ Donor Recovery Enhancement Program
The purpose of the study is to test if using these living donor-specific pre-transplant resources would lead to a better and faster recovery post-transplant.
- Trial name
- NCT03865264
- Testing
- Recovery Enhancement Program
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Markers in Plasma and Urine
MicroRNAs in Renal Recovery - Pilot Study
In this Pilot study, the potential of noncoding RNAs in renal recovery from acute kidney injury will be evaluated.
- Trial name
- NCT04381156
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Hydronephrosis
Clinical Significance of Supranormal Differential Renal Function in the Recovery of Hydronephrosis
The purpose of this study is to assess the clinical significance of supranormal differential renal function (DRF) in the recovery of unilateral hydronephrosis (HN) after surgery, pediatric patients who underwent pyeloplasty for…
- Trial name
- NCT01839006
- Testing
- dismembered pyeloplasty
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Seoul National University Hospital
Terlipressin Adverse Reaction, Ascites Hepatic
The Effect of Terlipressin on Recovery of Liver Function After Hepatectomy
Portal vein hypertension is associated with post-hepatectomy liver failure in patients with liver cirrhosis. Our previous study found that bolus injection of 1 mg terlipressin immediately after hepatectomy decreased portal vein…
- Conditions
- Terlipressin Adverse Reaction, Ascites Hepatic, Liver Failure, Acute Kidney Injury
- Trial name
- NCT04221672
- Testing
- Terlipressin plus standard care, Standard care
- Where
- 4 sites in China
- Volunteers
- 86 people
- Sponsor
- Shanghai Zhongshan Hospital
Circumcision, Hydrocelectomy
Enhanced Recovery After Urologic Surgery
This clinical trial aims to investigate the analgesic efficacy of several perioperative pain management strategies-specifically, epidural analgesia, paravertebral blockade, transversus abdominis plane (TAP) block, intravenous…
- Conditions
- Circumcision, Hydrocelectomy, Hernia, Renal Cyst
- Trial name
- NCT06789744
- Testing
- General Anesthesia (GA), Epidural Analgesia( 0.2% ropivacaine), Paravertebral block ( liposomal bupivacaine 133 mg or 0.2% ropivacaine)
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xiaguang Duan
Opioid Use, Kidney Diseases
Enhanced Recovery After Surgery in Kidney Transplant Donors
Enhanced recovery after surgery (ERAS) pathways are designed to optimize perioperative management, improving patient outcomes and satisfaction through multimodal techniques.
- Conditions
- Opioid Use, Kidney Diseases, Pain, Postoperative, Postoperative Complications
- Trial name
- NCT04110080
- Testing
- multimodal pain management, goal directed fluid management, preoperative carbohydrate loading
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University