Clinical trials: asthma
Allergic Rhinitis
Efficacy Study of Sublingual Immunotherapy to Treat Ragweed Allergies
The purpose of this study is to determine an effective dose range for the administration of ragweed allergenic extract via the sublingual route of administration
- Trial name
- NCT00599872
- Testing
- Standardized Ragweed Allergenic Extract
- Where
- 30 sites in United States
- Volunteers
- 430 people
- Sponsor
- Greer Laboratories
Asthma, COPD
Prospective evAluatIon foR Inhalation Devices Study
ASTHMA: Asthma is a chronic inflammatory disorder of the airways in which many different types of cells, and various cellular components.
- Trial name
- PAIR (NCT01800994)
- Where
- 6 sites in Greece
- Volunteers
- 750 people
- Sponsor
- Elpen Pharmaceutical Co. Inc.
Coronary Artery Disease, Congestive Heart Failure
Prognostic Indicators as Provided by the EPIC ClearView
The objective of this study is to determine whether the finger tip images captured by the EPIC ClearView device, when analyzed via the ClearView software, produce a Response Scale that characterizes trends consistent with known…
- Conditions
- Coronary Artery Disease, Congestive Heart Failure, Valvular Heart Disease, Atrial Fibrillation
- Trial name
- GBMC (NCT01476995)
- Where
- United States
- Volunteers
- 353 people, healthy volunteers welcome
- Sponsor
- Epic Research & Diagnostics, Inc.
Moderate-to-Severe Asthma
Effect of KB003 in Subjects With Asthma Inadequately Controlled by Corticosteroids
This study will evaluate the safety, tolerability and efficacy of a single dose level of KB003 in subjects with inadequately controlled asthma.
- Trial name
- KB003-04 (NCT01603277)
- Testing
- Anti-GM-CSF Monoclonal Antibody 400mg
- Where
- 70 sites in United States, Australia and 4 more
- Volunteers
- 160 people
- Sponsor
- Humanigen, Inc.
Asthma
A 3-week Study Investigating Patient Use and Functionality of Formoterol in a Novel Inhalation Device in Patients With Asthma
This study is designed to investigate the ability of patients with asthma to properly use a new multi-dose dry powder inhaler (MDDPI) device in a real-life situation.
- Trial name
- NCT00130351
- Testing
- formoterol
- Where
- 12 sites in United States
- Volunteers
- 155 people
- Sponsor
- Novartis
Asthma
Efficacy of Symbicort Versus Its Monocomponents - SPRUCE 80/4.5
The purpose of this study is to compare Symbicort with its monocomponents budesonide and formoterol in the treatment of asthma in children and adults
- Trial name
- NCT00651651
- Testing
- budesonide/formoterol, budesonide, formoterol
- Volunteers
- 450 people
- Sponsor
- AstraZeneca
Asthma
Montelukast Asthmatic Smoker Study (0476-332)(COMPLETED)
This is a multicenter study to evaluate the efficacy and safety of MK0476 versus placebo in participants with chronic asthma who actively smoke cigarettes.
- Trial name
- NCT00284856
- Testing
- montelukast sodium, Comparator: fluticasone
- Volunteers
- 1,640 people
- Sponsor
- Organon and Co
Asthma
A Trial of SHR-1905 in Healthy Subjects and Subjects With Mild Asthma
This study is a phase 1 single dose escalation study of SHR-1905 in healthy subjects and subjects with mild asthma. The purpose of the study is to evaluate the safety, tolerability and pharmacokinetics of SHR-1905 in healthy…
- Trial name
- NCT04905602
- Where
- China
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Shanghai Hengrui Pharmaceutical Co., Ltd.
Asthma
Safety and Tolerability of Omalizumab in Poorly Controlled Moderate to Severe Asthma Patients
This study will assess the safety and tolerability of long-term treatment with omalizumab plus current asthma therapy in patients who participated in and successfully completed the treatment period of study CIGE025IA04E1.
- Trial name
- NCT00482508
- Testing
- Omalizumab
- Volunteers
- 95 people
- Sponsor
- Novartis
Asthma
Evaluating the Efficacy and Safety of Fluticasone Furoate in the Treatment of Asthma in Adults and Adolescents
A randomised, double-blind, multi-centre study to evaluate the efficacy and safety of two doses of inhaled fluticasone furoate in the treatment of persistent asthma in adults and adolescents currently receiving mid to high…
- Trial name
- NCT01431950
- Testing
- fluticasone furoate, albuterol/salbutamol
- Where
- 40 sites in United States, Argentina and 4 more
- Volunteers
- 238 people
- Sponsor
- GlaxoSmithKline
Asthma Chronic
Pilot Voice Sample Collection From People With Asthma
Human speech is as unique as a fingerprint and analysing speech had advanced so much that speech can now be used instead of PIN numbers in banking.
- Trial name
- NCT04799678
- Testing
- Recording voice samples
- Volunteers
- 75 people
- Sponsor
- Thomas Antalffy
Healthy, Asthma
A Pilot Study to Assess the Safety Profile of resB®
The study investigates the safety and tolerability of 4-week, twice daily supplementation of resB® Lung Support in asthma patients and healthy participants.
- Trial name
- NCT05173168
- Testing
- Probiotic Dietary Supplement
- Where
- Ireland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- ResBiotic Nutrition, Inc.
Asthma, Aspirin-Induced
Oral Ifetroban to Treat Aspirin Exacerbated Respiratory Disease (AERD)
The purpose of this phase 2 study is to assess the safety and efficacy of oral ifetroban for the treatment of aspirin-exacerbated respiratory disease (AERD).
- Trial name
- NCT03028350
- Testing
- Ifetroban Oral Capsule
- Where
- 16 sites in United States
- Volunteers
- 54 people
- Sponsor
- Cumberland Pharmaceuticals
Asthma
Post-marketing Surveillance (PMS) Study to Observe the Safety and Effectiveness of ARNUITY in Asthma Subjects in a Real World Setting
This is an open-label, multi-center, PMS study to observe the safety and effectiveness of ARNUITY administered in asthma subjects in a real world setting.
- Trial name
- NCT03595930
- Testing
- Arnuity
- Where
- South Korea
- Volunteers
- 668 people
- Sponsor
- GlaxoSmithKline
Asthma
A Study of Lebrikizumab (MILR1444A) in Adult Patients With Asthma Who Are Inadequately Controlled on Inhaled Corticosteroids
This is a randomized, double-blind, placebo-controlled study to evaluate the effects of lebrikizumab in patients with asthma who remain inadequately controlled while on chronic therapy with inhaled corticosteroids (ICS).
- Trial name
- MILLY (NCT00930163)
- Testing
- lebrikizumab (MILR1444A)
- Volunteers
- 218 people
- Sponsor
- Genentech, Inc.
Allergy, Asthma
A Study Investigating the Immunologic Effects and Safety of 60-day Treatment of the ALK HDM Tablets in Adult Subjects With HDM-Induced Allergic Rhinitis and/or Atopic Asthma
To demonstrate superiority of ALK HDM tablets versus placebo in immune response, measured as change of D.farinae specific immunoglobulin G4 (IgG4) from baseline to end of treatment with ALK HDM tablets given once daily over 60…
- Conditions
- Allergy, Asthma, Rhinitis
- Trial name
- NCT02596321
- Testing
- Mitizax
- Where
- 9 sites in Belarus, Russia
- Volunteers
- 112 people
- Sponsor
- Abbott
Asthma
Efficacy and Safety Evaluation of Budesonide/Formoterol SPIROMAX® Inhalation Powder Versus SYMBICORT® TURBOHALER®
The primary objective of the study is to establish whether budesonide/formoterol fumarate dihydrate (BF) Spiromax 160/4.5 micrograms (mcg) is as effective as Symbicort Turbohaler 200/6 mcg administered twice daily in participants…
- Trial name
- NCT01803555
- Testing
- Budesonide/Formoterol SPIROMAX®, SYMBICORT® TURBOHALER®
- Where
- 114 sites in Austria, Belgium and 14 more
- Volunteers
- 605 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Asthma,, Pharmacokinetics,
Phase I Study to Assess the Effect on Healthy Male Volunteers of Ketoconazole on the Pharmacokinetics of a Single Dose of AZD5069 Administered Orally.
The main purpose of the study is to compare the change of the AZD5069 Pharmacokinetic profile when administered with ketoconazole.
- Conditions
- Asthma,, Pharmacokinetics,, Cmax,, Tmax,
- Trial name
- NCT01735240
- Testing
- AZD5069, Ketoconazole
- Where
- United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Bronchial Asthma
Clinical Assessment Of GW815SF HFA MDI In Pediatric Patients With Bronchial Asthma
To evaluate the efficacy and safety of GW815SF HFA MDI 25/50µg 1 inhalation bid in comparison with concomitant treatment with salmeterol xinafoate DPI 25µg 1 inhalation bid plus fluticasone propionate DPI 50µg 1 inhalation bid in…
- Trial name
- NCT00448435
- Testing
- GW815SF HFA MDI, salmeterol and fluticasone propionate
- Where
- 8 sites in Japan
- Volunteers
- 51 people
- Sponsor
- GlaxoSmithKline
Asthma
A Safety and Efficacy Study of Inhaled R940343 in Patients With Mild to Moderate Asthma
The purpose of this study is to determine the safety, efficacy and tolerability of R940343 in the treatment of mild to moderate asthma.
- Trial name
- SITAR (NCT01591044)
- Testing
- R940343 1mg, R940343 2mg
- Where
- 59 sites in United States, Canada
- Volunteers
- 301 people
- Sponsor
- Rigel Pharmaceuticals
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