Clinical trials: asthma
Asthma
Efficacy and Safety Study of Reslizumab to Treat Poorly Controlled Asthma
The purpose of this study is to determine the effectiveness and safety of reslizumab in the treatment of subjects with poorly controlled asthma.
- Trial name
- NCT00587288
- Testing
- Reslizumab, Saline
- Where
- 30 sites in United States, Canada
- Volunteers
- 106 people
- Sponsor
- Ception Therapeutics
Asthma
Chronic Bronchiolitis or Resistant Asthma?
Chronic Bronchiolitis or Resistant Asthma? Testing a way to diagnosis and treatment
- Trial name
- NCT00368342
- Testing
- Erythromycin, Azithromycin , Clarithromycin
- Sponsor
- Baqiyatallah Medical Sciences University
Asthma, Airway Hyperresponsiveness
Small Airways Disease in Asymptomatic and Symptomatic Subjects With Airway Hyperresponsiveness (AHR)
The purpose of this study is to study differences in small airways (<2mm) parameters in asthma patients, subjects with asymptomatic airway hyperresponsiveness and healthy controls.
- Trial name
- ABHR (NCT01549483)
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Severe Asthma
Evaluate the Efficacy and Safety of TQC2731 Injection in Patients With Severe Asthma.
This is a phase II, multicenter, double-blind, randomized, parallel group, placebo-controlled clinical study to evaluate the effect of three doses of TQC2731 on Annualized Asthma Exacerbation Rates(AAER) in adult subjects with…
- Trial name
- NCT05472324
- Testing
- TQC2731 injection
- Where
- 2 sites in China
- Volunteers
- 205 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Asthma
A Pilot Study Into Health Pre and Post Treatment With Intravenous Aminophylline and Hydrocortisone in Severe Asthmatics
This study focuses on severe asthmatics and their asthma symptoms. 40% of asthma patients continue to experience symptoms and up to 5% of these have difficult-to-control asthma despite continually improving treatments.
- Trial name
- SARAH (NCT02270827)
- Testing
- Aminophylline, Hydrocortisone
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Agents, Anti Asthmatic, Asthma in Children
In Vivo Efficacy of Salbutamol (Sandoz) Versus Salbutamol Ventolin (GSK) in Children With Asthma
In this study, the investigators hypothesize that the reference product (SalbR/Ventolin) is more effective than SalbG (Salbutamol Sandoz) at improving the lung function in children with asthma, and that this difference increases…
- Trial name
- Salsa (NCT05884970)
- Testing
- "100 mcg Salbutamol Sandoz" and "300 mcg Salbutamol Sandoz", "100 mcg Salbutamol Sandoz" and "300 mcg Salbutamol Ventolin GSK", "100 mcg Salbutamol Ventolin GSK" and "300 mcg Salbutamol Sandoz"
- Where
- Netherlands
- Volunteers
- 80 people
- Sponsor
- Canisius-Wilhelmina Hospital
Allergic Bronchopulmonary Aspergillosis
Deflazacort Vs. Prednisolone in Acute-stage ABPA
Oral glucocorticoids are currently the treatment of choice for allergic bronchopulmonary aspergillosis (ABPA). They not only suppress the immune hyperfunction but are also anti-inflammatory.
- Trial name
- NCT04227483
- Testing
- Deflazacort, Prednisolone
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pediatric Asthma
The Puerto Rico Asthma Integrated Response Program ("PR-AIR")
The purpose of this study is to adapt and deliver an evidence-based multi-level intervention to reduce asthma disparities, and that promote and improve population health in the high-burden communities of San Juan, Puerto Rico.
- Trial name
- PR-AIR (NCT05999032)
- Testing
- CASE in person version (High Intensity Package), CASE-V remote version (Low Intensity Package), CASE and HARP in person (High Intensity package)
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 480 people
- Sponsor
- Rhode Island Hospital
Asthmatic Patients
Social-Economics Profile of the Asthmatic Patients Attended at Nucleus of Integrated Medical Care
This study had a descriptive, retrospective, transversal character with quantitative approach, which aimed to delineate the social-economics profile of the asthmatic patients that used the health service available at the Care…
- Trial name
- NCT00722657
- Volunteers
- 40 people
- Sponsor
- Fortaleza University
Asthma
Combined Effects of Inspiratory Muscles Training With Pilate Training in Asthma Patients
Asthma is a chronic (long-term) condition that affects the airways in the lungs. The airways are tubes that carry air in and out of your lungs. In asthma the airways can become inflamed and narrowed at times.
- Trial name
- NCT06762236
- Testing
- Pillatate Training
- Where
- Pakistan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Asthma
A Study on the Diagnostic Value of the Methacholine Choline Provocation Test in the Asthmatic Population
This study was a multicenter, open, observational study and was divided into two stages; Stage I study includes patients with suspected asthma to observe the diagnostic value and safety of Methacholine Choline Provocation Test.
- Trial name
- NCT05870436
- Testing
- Methacholine Choline Provocation Test
- Where
- 6 sites in China
- Volunteers
- 1,100 people
- Sponsor
- jingping Zheng
Asthma
Management of Asthma Patients Guided by Exhaled Nitric Oxide (eNO)
This study is designed to show that pharmacotherapy guided by eNO and clinical standard of care produces a superior outcome to trial-based therapy guided by clinical standard of care alone.
- Trial name
- Outcomes (NCT00739219)
- Testing
- Apieron Insight eNO monitor
- Where
- 12 sites in United States
- Volunteers
- 260 people
- Sponsor
- Apieron
Asthma
A Phase 1 Study of CNTO 3157 in Healthy Volunteers and Patients With Asthma
This is a phase 1, safety study of CNTO 3157 in healthy subjects and subjects with asthma.
- Trial name
- NCT01195207
- Where
- 4 sites in Belgium, Germany and 1 more
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Centocor, Inc.
Multimorbidity, Chronic Asthma
Impact of Multi-Component Intervention on Suspected Asthma Population
Study Participants: Suspected asthma population, defined as individuals whose score of asthma screening questionnaire used in ECRHS study exceeds 0 and whose age is 35 and above.
- Conditions
- Multimorbidity, Chronic Asthma, Population Medicine
- Trial name
- POPMIX-Asthma (NCT06457009)
- Testing
- Multi-component Intervention Package
- Where
- China
- Volunteers
- 9,194 people
- Sponsor
- Peking Union Medical College
Asthma
Safety Study in Adolescent and Adult Patients With Asthma
E004-C2 is a continuation of E004-C for safety evaluations with additional 3 months to be able to assess the 6-month safety profile for E004 (epinephrine inhalation) versus placebo in a double-blinded manner.
- Trial name
- NCT01476904
- Testing
- Primatene Mist, Epinephrine inhalation
- Where
- 27 sites in United States
- Volunteers
- 208 people
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Infant Conditions, Infant, Premature, Diseases
The Alberta BLOOM Premature Child Study
This is a prospective, observational clinical cohort study involving 405 children born premature (at less than 37 weeks gestation) and their mother/parent/guardian.
- Conditions
- Infant Conditions, Infant, Premature, Diseases, Asthma, Asthma in Children
- Trial name
- BLOOM-PCS (NCT05011071)
- Where
- Canada
- Volunteers
- 535 people
- Sponsor
- University of Calgary
Alopecia Areata, Depressive Episode
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata
This study series consists of four related studies and aims to explore and describe many important elements of alopecia areata over three key areas: (1) the current epidemiology of alopecia areata, (2) the prevalence and…
- Conditions
- Alopecia Areata, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04239521
- Testing
- Exposure of interest (studies 2 & 3).
- Where
- United Kingdom
- Volunteers
- 51,955 people
- Sponsor
- Momentum Data
Hypertension, Diabetes Mellitus, Type 2
ENCOMPASS: Expansion Study A, RCT
Some patients living with multiple long-term health conditions have difficulty accessing the services they need, despite available primary care and community resources.
- Conditions
- Hypertension, Diabetes Mellitus, Type 2, Chronic Kidney Diseases, Ischemic Heart Disease
- Trial name
- ENCOMPASS (NCT04790604)
- Testing
- Community Health Navigator Program
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- University of Calgary
Obesity, Asthma
Obesity and Asthma:a Specific Phenotype
Clinicians frequently observed that obese women referred for severe asthma do not respond to treatment. These patients, despite the presence of wheezing, often have normal expiratory flows and normal or "borderline" airway…
- Trial name
- ORPA (NCT00532363)
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Laval University
Rhinitis, Allergic, Asthma, Allergic
Food-specific IgG4-guided Elimination Diets Improve Allergy Symptoms in Children
Allergic diseases in children are major public health concerns due to their widespread and rising prevalence. The most classic pathway to trigger allergy is type I allergy mediated by immunoglobulin E(IgE), but the role of…
- Conditions
- Rhinitis, Allergic, Asthma, Allergic, Conjunctivitis, Allergic, Atopic Dermatitis
- Trial name
- NCT06063044
- Where
- China
- Volunteers
- 407 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
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